KR101329261B1 - Functional non-woven fabric using chitosan and manufacturing method therof - Google Patents

Functional non-woven fabric using chitosan and manufacturing method therof Download PDF

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KR101329261B1
KR101329261B1 KR1020120051933A KR20120051933A KR101329261B1 KR 101329261 B1 KR101329261 B1 KR 101329261B1 KR 1020120051933 A KR1020120051933 A KR 1020120051933A KR 20120051933 A KR20120051933 A KR 20120051933A KR 101329261 B1 KR101329261 B1 KR 101329261B1
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chitosan
nonwoven fabric
acid
fibers
functional
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Korean (ko)
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이창헌
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(주)태봉
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    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4382—Stretched reticular film fibres; Composite fibres; Mixed fibres; Ultrafine fibres; Fibres for artificial leather
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45D—HAIRDRESSING OR SHAVING EQUIPMENT; EQUIPMENT FOR COSMETICS OR COSMETIC TREATMENTS, e.g. FOR MANICURING OR PEDICURING
    • A45D44/00—Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
    • A45D44/002—Masks for cosmetic treatment of the face
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01G—PRELIMINARY TREATMENT OF FIBRES, e.g. FOR SPINNING
    • D01G13/00—Mixing, e.g. blending, fibres; Mixing non-fibrous materials with fibres
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01G—PRELIMINARY TREATMENT OF FIBRES, e.g. FOR SPINNING
    • D01G15/00—Carding machines or accessories; Card clothing; Burr-crushing or removing arrangements associated with carding or other preliminary-treatment machines
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/425—Cellulose series
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4266—Natural fibres not provided for in group D04H1/425
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/44—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties the fleeces or layers being consolidated by mechanical means, e.g. by rolling
    • D04H1/46—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties the fleeces or layers being consolidated by mechanical means, e.g. by rolling by needling or like operations to cause entanglement of fibres
    • D04H1/492—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties the fleeces or layers being consolidated by mechanical means, e.g. by rolling by needling or like operations to cause entanglement of fibres by fluid jet
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H13/00—Other non-woven fabrics
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2401/00—Physical properties
    • D10B2401/13—Physical properties anti-allergenic or anti-bacterial
    • D—TEXTILES; PAPER
    • D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
    • D10B2509/00—Medical; Hygiene

Abstract

The present invention relates to a functional non-woven fabric using chitosan and a manufacturing method thereof. A chitosan fiber and a cotton fiber are formed into a non-woven fabric, followed by acid treatment. As a result, the chitosan contained in the non-woven fabric is gelled, and thus the gelled chitosan can directly react with the skin. Specifically, the chitosan fiber and the cotton fiber are mixed with each other, and the mixture is subjected to carding and water punching, thereby manufacturing the non-woven fabric. An acid solution of pH 2.2 to 2.9 is input onto the non-woven fabric to gel the chitosan contained in the non-woven fabric.

Description

키토산을 이용한 기능성 부직포 및 그 제조방법{FUNCTIONAL NON-WOVEN FABRIC USING CHITOSAN AND MANUFACTURING METHOD THEROF}Functional nonwoven fabric using chitosan and its manufacturing method {FUNCTIONAL NON-WOVEN FABRIC USING CHITOSAN AND MANUFACTURING METHOD THEROF}

본 발명은 키토산을 이용한 기능성 부직포 및 그 제조방법에 관한 것으로, 키토산 섬유와 면 섬유로 부직포를 성형한 후, 이를 산처리하여 부직포에 포함된 키토산을 겔화함으로써, 겔화된 키토산이 피부에 직접적으로 반응할 수 있도록 한 것이다.The present invention relates to a functional nonwoven fabric using chitosan and a method for manufacturing the same, and after forming the nonwoven fabric with chitosan fiber and cotton fiber, acid treatment is performed to gel the chitosan contained in the nonwoven fabric so that the gelated chitosan reacts directly to the skin. It is to be done.

팩이란 피부에 영향을 줄 수 있는 물질을 원하는 부위에 사용하여 일정시간 방치함으로써 피부에 원하는 효과를 볼 수 있도록 한 것이다. 팩은 피부에 수분을 공급 유지시키는 보습작용, 피부오염물질을 흡착, 제거하는 청정작용 및 혈액순환 촉진작용 등을 수행하므로써 피부를 건강하고 아름답게 가꾸어주는 주요 화장품으로 오래 전부터 사용해 오고 있다. 이러한 팩 화장품은 얼굴뿐만 아니라 목, 어깨, 팔, 다리 등의 국소용 또는 신용으로 사용될 수 잇는데, 젤리상, 페이스트상, 분말상으로 사용되는 필 오프 타입(peel-off type), 크림상, 점토상, 젤리상, 에어졸로 사용되는 티슈오프타입(tissue-off type) 및 워시 오프 타입(wash- off type), 고화 후 벗겨내는 박리타입, 부직포 젤, 부직포 함침형 도포타입 등의 형태로 다양하게 제조되고 있다.Pack is to use the material that can affect the skin in the desired area and leave it for a certain time to see the desired effect on the skin. The pack has been used for a long time as a major cosmetic product that keeps skin healthy and beautiful by moisturizing, maintaining moisture, and adsorbing and removing skin pollutants, and promoting blood circulation. These pack cosmetics can be used for topical or credit not only the face but also the neck, shoulders, arms and legs. Peel-off type, cream and clay , Jelly, Tissue-off type and wash-off type used as aerosol, peel-off type after solidification, nonwoven gel, nonwoven fabric impregnated coating type, etc. It is becoming.

이들 각각은 서로 장단점을 가지고 있기 때문에 제품을 제형화하는 연구자들은 다양한 소비자의 기호에 따라 적당한 형태의 제형을 선정하여 이들의 단점을 보완하고 있다.Each of these has advantages and disadvantages, and researchers formulating products compensate for their shortcomings by choosing the right type of formulation according to various consumer preferences.

한편, 키틴은 식물의 셀룰로오스(섬유소)와 유사한 구조를 갖는 분자량 2만 이상의 천연 다당류이며 새우 등의 갑각류 및 균류나 조류 등의 고등 식물 세포벽에 존재하는 천연 고분자 물질이다. 그리고 키토산은 키틴을 강알칼리로 탈아세틸화하여 얻어지는 물질로, 저농도 산성 용액에 잘 용해되는 특징을 가지고 있다.On the other hand, chitin is a natural polysaccharide having a molecular weight of 20,000 or more having a structure similar to that of cellulose (fibrin) of plants, and is a natural high molecular substance present in shell cells of shellfish such as shrimp and higher plant cells such as fungi and algae. Chitosan is a substance obtained by deacetylating chitin with strong alkali, and has a characteristic of being dissolved in a low concentration acidic solution.

이러한 키틴과 키토산은 무독성, 환경 친화성, 생분해성 및 생체 적합성이 우수하여 여러 의료용 분야에 많이 활용되고 있는데 특히 Prudden 등은 상기 키틴 및 키토산 제제가 상처 치유를 촉진시키는 효과가 있음을 보고한 바 있으며(L. L. Balassa 및 J. F. Prudden, Proc. 1st International Conference Chitin/Chitosan, MIT (1977) 296∼297쪽), 또 이들은 어떤 성분이 상처치유 효과에 기여하는가를 연구한 결과, 키틴의 구성단위인 N-아세틸글루코스아민과 키토산의 구성단위인 글루코스아민이 상처치유에 관여한다는 결론을 얻었다.Such chitin and chitosan are widely used in various medical fields because of their high toxicity, environmental friendliness, biodegradability, and biocompatibility. In particular, Prudden et al. Reported that the chitin and chitosan preparations promote wound healing. (LL Balassa and JF Prudden, Proc. 1st International Conference Chitin / Chitosan, MIT (1977) pp. 296-297), and they also studied which components contribute to the wound healing effect. It was concluded that glucoseamine, a structural unit of glucoseamine and chitosan, is involved in wound healing.

더욱이 키토산은 인간, 동물, 식물 등의 조직이나 체내에서 우수한 생체 적합성을 나타내고, 쉽게 분해되어 환경친화적이며 독성이 거의 없어 소재로서, 안전하고, 분말, 섬유, 막, 스폰지형 구조체 등 성형성이 우수하고, 점성, 보습성, 금속흡착성, 항균, 항곰팡이활성 등의 기능을 보유하고 있다. 키토산을 섭취시 체내에서 약 40% 정도가 흡수되며 나머지 60%는 체외배설전까지 세포를 활성화시켜 노화를 억제하고 면역력을 강화하여 항암작용, 탈콜레스테롤 작용, 간기능 개선작용, 체내 중금속 및 오염물질 배출 등 인체의 생체조절기능에 중요한 역할을 수행한다.Furthermore, chitosan shows excellent biocompatibility in tissues and bodies of humans, animals, plants, etc., and is easily decomposed, environmentally friendly, and almost non-toxic. It possesses functions such as viscosity, moisture retention, metal adsorption, antibacterial activity and antifungal activity. When ingesting chitosan, about 40% is absorbed in the body, and the remaining 60% activates the cells before ex vivo excretion, inhibits aging and strengthens immunity, thereby improving anti-cancer, decholesterol, liver function, and release of heavy metals and contaminants in the body. It plays an important role in the body's bioregulatory function.

따라서 상기한 키토산을 팩, 거즈 등의 직물에 적용하기 위하여 많은 연구가 거듭되었는 바, 일본공개특허 소 57-1435008호에서는 키틴섬유로부터 제조되는 거즈가 제안되었는데 거즈의 물리적 특성만을 제시하고 있으며, 일본특허 제 8211258에서는 단지 여러종류의 재료를 복합하는 과정에서 키틴성분이 단지 접착성능을 발휘하는 용도로만 사용되었다. Therefore, many studies have been conducted to apply the above-described chitosan to fabrics such as packs and gauze. Japanese Laid-Open Patent Publication No. 57-1435008 proposes a gauze made from chitin fibers, and shows only physical properties of the gauze. In patent 8211258, the chitin component is used only for the purpose of exerting adhesive performance in the process of compounding various kinds of materials.

또한 국내특허 제2001-19732호는 키토산을 함유하는 기능성 섬유의 제조방법을; 국내 특허 제10-0589958호에는 키토산 및 무기염을 혼합 사용하여 필름의 인장강도를 높이고 항균력이 있는 팩용 화장료 조성물이 개시되어 있으나, 국내특허 제2000-66617호는 키틴으로부터 얻은 분자량이 높은 고순도의 키토산을 사용하여 피복능을 획기적으로 향상시키는 무정형 수용성 키토산 필름 제조방법을 개시하고 있다. In addition, Korean Patent No. 2001-19732 discloses a method for producing a functional fiber containing chitosan; Korean Patent No. 10-0589958 discloses a cosmetic composition for packs having a high tensile strength and antibacterial effect by mixing chitosan and inorganic salts, but Korean Patent No. 2000-66617 discloses a high-purity chitosan having a high molecular weight obtained from chitin. Discloses a method for producing an amorphous water-soluble chitosan film that significantly improves the coating ability by using a.

그러나 이러한 제품들은 키토산이 소량만이 첨가되어 키토산의 기능발현이 미미할 뿐 아니라, 필름은 기공이 전혀 형성되지 않아 피부의 수분을 빼앗는 역할을 하는 단점이 있으며, 필름을 건조하여야 하나 필름의 건조 속도가 늦어 생산성 등이 좋지 못한 문제점이 있었다.However, these products have only a small amount of chitosan, so that the functional expression of chitosan is insignificant, and the film does not form pores at all, which deprives the skin of moisture. There was a problem that productivity is not good late.

또한 일반적으로 키토산의 성형 가공성이 우수한 것으로 알려져 있으나 이는 기존의 주성분에 키토산을 소량의 첨가제로 사용하였을 경우이며 키토산을 주 성분으로 사용하는 경우에는 섬유, 막, 시트형 구조체가 부드럽지 못한 특성을 보유함에 따라 거즈, 붕대, 마스크 팩 등으로의 활용이 제한되는 문제점이 있었다.In addition, it is generally known that chitosan has excellent molding processability, but this is when the chitosan is used as a small amount of additive in the existing main component, and when the chitosan is used as the main component, the fiber, membrane, and sheet-like structures have a soft property. Accordingly, there was a problem that the utilization of gauze, bandages, mask packs, etc. is limited.

따라서 본 발명은 상기한 종래의 키토산 팩 또는 필름 등이 갖는 제반 문제점을 해결하기 위한 것으로, 키토산 섬유와 면 섬유로 부직포를 성형한 후, 이를 산처리하여 부직포에 포함된 키토산을 겔화함으로써, 부직포에 함유된 겔화된 키토산이 피부에 직접적으로 반응할 수 있도록 하는 것을 목적으로 한다.Accordingly, the present invention is to solve the above problems of the conventional chitosan pack or film, and by forming a nonwoven fabric with chitosan fibers and cotton fibers, and then acid-treated to gel the chitosan contained in the nonwoven fabric, It is aimed at allowing the contained gelled chitosan to react directly to the skin.

또한 부직포에 포함된 키토산이 겔화됨으로써, 키토산의 함량을 높이더라도 부직포가 부드러운 특성을 갖도록 하여 화장품용 마스크 팩은 물론, 거즈, 붕대, 창상치료제 등의 의약외품으로의 활용이 가능하도록 하는 것을 목적으로 한다.In addition, the chitosan contained in the nonwoven fabric is gelated, so that the nonwoven fabric has a soft characteristic even if the chitosan content is increased, so that it can be used as a non-medicinal product such as gauze, bandage, and wound treatment as well as a cosmetic mask pack. .

본 발명의 키토산을 이용한 기능성 부직포는 키토산 섬유와 면 섬유가 혼합되어 이루어지되, 상기 키토산 섬유의 키토산은 겔화된 상태인 것을 특징으로 한다.Functional nonwoven fabric using chitosan of the present invention is made of a mixture of chitosan fiber and cotton fiber, the chitosan of the chitosan fiber is characterized in that the gelled state.

여기서 상기 키토산은 산에 의해 겔화된 것을 특징으로 한다.Wherein the chitosan is gelled by acid.

여기서 상기 산은 아스코르브산 또는 구연산인 것을 특징으로 한다.Wherein the acid is ascorbic acid or citric acid.

여기서 상기 부직포는 키토산 섬유 20~60중량%와 면 섬유 40~80중량%가 혼합되어 이루어지는 것을 특징으로 한다.Here, the nonwoven fabric is characterized in that the mixture of 20 to 60% by weight of chitosan fibers and 40 to 80% by weight of cotton fibers.

여기서 상기 부직포는 마스크 팩, 거즈, 붕대, 창상치료제 중 어느 하나로 사용되는 것을 특징으로 한다.Wherein the non-woven fabric is characterized in that it is used as any one of a mask pack, gauze, bandages, wound treatment.

본 발명의 제조방법은, 키토산 섬유와 면 섬유를 혼합하는 단계와, 상기 혼합된 키토산 섬유와 면 섬유를 카딩 및 워터펀칭하여 부직포로 제조하는 단계와, 상기 부직포에 pH 2.2~2.9의 산용액을 투입하여 상기 부직포 내에 포함된 키토산을 겔화하는 단계를 포함하여 이루어지는 것을 특징으로 한다.The manufacturing method of the present invention comprises the steps of mixing the chitosan fibers and cotton fibers, and manufacturing the nonwoven fabric by carding and water punching the mixed chitosan fibers and cotton fibers, acid solution of pH 2.2 ~ 2.9 in the nonwoven fabric It characterized in that it comprises a step of gelling chitosan contained in the nonwoven by the input.

여기서 상기 산용액은 물 또는 마스크 팩용 에센스에 아스코르브산 또는 구연산을 투입하여 이루어지는 것을 특징으로 한다.The acid solution is characterized in that the ascorbic acid or citric acid is added to the essence for water or mask pack.

여기서 상기 부직포는 키토산 섬유 20~60중량%와 면 섬유 40~80중량%가 혼합되어 이루어지는 것을 특징으로 한다.Here, the nonwoven fabric is characterized in that the mixture of 20 to 60% by weight of chitosan fibers and 40 to 80% by weight of cotton fibers.

여기서 상기 키토산을 겔화하는 단계 후, 이를 중화제로 pH 5.5~6.0으로 중화하는 단계를 더 포함하는 것을 특징으로 한다.Here, after the step of gelling the chitosan, characterized in that it further comprises the step of neutralizing it to pH 5.5 ~ 6.0 with a neutralizing agent.

본 발명에 따르면 부직포 내에 키토산이 겔화되어 포함됨으로써, 다량의 키토산을 부직포 내에 포함시키더라도 부직포가 뻣뻣해지지 않아, 화장품용 마스크 팩, 붕대, 거즈, 창상치료제 등의 의약외품으로의 활용이 가능하게 되는 효과가 있다.According to the present invention, the chitosan is gelled and included in the nonwoven fabric, so that the nonwoven fabric does not become stiff even when a large amount of chitosan is contained in the nonwoven fabric, so that it can be used as a non-medicinal product such as a cosmetic mask pack, a bandage, a gauze, and a wound treatment agent. There is.

또한 키토산의 함량을 종래에 비해 늘릴 수 있어 항균성 및 재생성, 보습성이 우수한 부직포의 제조가 가능하게 되는 효과가 있다. In addition, it is possible to increase the content of chitosan compared to the conventional has the effect that it is possible to manufacture a non-woven fabric excellent in antibacterial and reproducible, moisturizing.

이하 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.

먼저 본 발명의 부직포는 마스크 팩 등의 화장품, 붕대, 거즈, 창상치료제 등의 의약외품에 사용될 수 있는 것으로, 항균, 보습, 재생 등을 목적으로 하는 제품에의 활용을 제한하지 않는다.First, the nonwoven fabric of the present invention can be used in cosmetics, such as mask packs, bandages, gauze, wound and other quasi-drugs, etc., and does not limit the use of the product for the purpose of antibacterial, moisturizing, regenerating, and the like.

본 발명의 부직포는 키토산 섬유와 면 섬유가 혼합되어 이루어지는 데, 상기 부직포 내, 즉 상기 키토산 섬유의 키토산은 겔화된 상태인 것이 특징이다.The nonwoven fabric of the present invention is a mixture of chitosan fibers and cotton fibers, characterized in that the chitosan in the nonwoven fabric, that is, the chitosan fibers is in a gelled state.

이는 상기 키토산의 겔화를 통해 키토산이 피부에 직접적으로 작용하도록 하는 것은 물론, 부직포의 제조시 키토산의 함량이 많을 경우 겔화 후 제품의 형태가 유지되지 않고 변형되는 등의 문제점을 해결하기 위한 것이다.This is intended to solve the problem that the chitosan directly acts on the skin through the gelation of the chitosan, as well as the form of the product is not maintained after gelation when the chitosan content is high when the nonwoven fabric is manufactured.

상기 키토산의 겔화를 위하여 본 발명에서는 상기 제조된 부직포 섬유를 산처리하는 것으로, 상기 산처리를 통해 면은 그 형태를 그대로 유지하고, 키토산은 섬유상태에서 겔처럼 녹아 마치 그 형상에 겔(Gel)원단과 유사하게 되는 것이다. In the present invention for the gelatinization of the chitosan, the prepared nonwoven fabric is acid-treated, the surface is maintained as it is through the acid treatment, chitosan is melted like a gel in the fiber state as if the gel (Gel) It will be similar to the fabric.

따라서 상기한 겔화된 키토산을 포함하는 부직포를 마스크 팩은 물론, 창상치료제 및 피부질환치료제 등에 적용시켜, 키토산의 항균성, 재생성, 보습성, 피부주름개선 등의 다양한 기능을 활용토록 하는 것이다.Therefore, the nonwoven fabric containing the gelled chitosan is applied to a wound pack and skin disease treatment, as well as a mask pack, to utilize various functions such as antibacterial, regenerating, moisturizing, and wrinkle improvement of chitosan.

이때 상기 산처리는 물 또는 화장용 에센스에 아스코르브산(L-Ascorbic Acid) 또는 구연산을 혼합하여 pH를 2.2~2.9의 산용액을 만든 후 이를 부직포와 함께 투입하여 부직포 내의 키토산이 겔화되도록 하는 것이다.At this time, the acid treatment is a mixture of ascorbic acid (L-Ascorbic Acid) or citric acid in water or cosmetic essence to make an acid solution of pH 2.2 ~ 2.9 and put it together with the non-woven fabric to allow the chitosan in the non-woven fabric to gel.

본 발명에서는 산으로서 아스코르브산 또는 구연산을 활용하였지만, 이외에도 식약청에 등재되어 있는 안전한 산이라면 어떠한 것이라도 활용할 수 있다.
In the present invention, ascorbic acid or citric acid is used as the acid, but any acid can be used as long as it is a safe acid listed by the KFDA.

이하 본 발명의 기능성 부직포의 제조방법에 대해 설명하면서 본 발명의 부직포에 대해서도 좀더 상세히 설명한다.Hereinafter, the nonwoven fabric of the present invention will be described in more detail with reference to the manufacturing method of the functional nonwoven fabric of the present invention.

기능성 부직포의 제조방법은 먼저, 재료를 칭량하는 것인데 본 발명에서의 재료란 키토산 섬유와 면 섬유이다.The manufacturing method of a functional nonwoven fabric is first weighing a material, but the material in this invention is chitosan fiber and cotton fiber.

그리고 상기 재료의 칭량이 끝나면 상기 키토산 섬유와 면 섬유를 혼합하는 바, 그 혼합비는 키토산 섬유 20~60중량%와 면 섬유 40~80중량%가 되는 것이 바람직하다. 이는 상기 키토산 섬유가 20중량% 미만으로 투입되게 되면 종래 기술들의 팩제 또는 거즈와 마찬가지로 키토산의 함량이 적어 그 기능성이 미미하게 되고, 키토산 섬유가 60중량%를 초과할 경우 가격이 상승되어 가격경쟁력이 저하될 뿐 아니라 면 섬유의 함량이 줄어 키토산 섬유를 겔화할 경우 부직포의 형태 유지가 어렵게 되는 등의 문제가 있기 때문이다.When the weighing of the material is finished, the chitosan fiber and the cotton fiber are mixed, and the mixing ratio is preferably 20 to 60% by weight of the chitosan fiber and 40 to 80% by weight of the cotton fiber. When the chitosan fiber is less than 20% by weight, the content of the chitosan is small, as is the case of the prior art packs or gauze, and its functionality is insignificant. This is because not only the content of cotton fibers is reduced, but also the difficulty of maintaining the shape of the nonwoven fabric when the chitosan fibers are gelled.

또한 본 발명의 키토산 섬유란 종래 기술들을 통해 충분히 공지된 것으로, 그 종류를 제한하지 않는 바 시중에서 판매되고 있는 어떠한 것이라도 활용이 가능하다.In addition, the chitosan fiber of the present invention is well known through the prior art, it is possible to utilize any commercially available bar without limiting its kind.

상기와 같이 재료가 혼합되면, 상기 혼합된 키토산 섬유와 면 섬유를 카딩 및 워터펀칭하여 부직포로 제조한다. 상기 카딩이란 원료의 성형(부직포화)을 위한 준비 공정으로 원료 상태를 가지런히 정리해 주는 단계이며, 워터펀칭이란 고압의 물을 섬유 사이로 통과시켜 섬유가 서로 얽히게 함으로써 부직포로서 성형하는 단계이다. 상기 카딩과 워터펀칭은 부직포를 제조하는 분야에서 이미 공지된 사항이므로 그 상세한 설명은 생략한다.When the materials are mixed as described above, the mixed chitosan fibers and cotton fibers are carded and waterpunched to prepare a nonwoven fabric. The carding is a step of uniformly arranging the raw material state in a preparation process for forming a raw material (nonwoven fabric), and water punching is a step of forming a nonwoven fabric by passing high-pressure water through the fibers to entangle the fibers. The carding and water punching are well known in the field of producing a nonwoven fabric, so that a detailed description thereof will be omitted.

상기와 같이 부직포가 제조되면, 이를 롤링, 규격에 맞게 슬리팅하고, 타공, 폴딩 등의 가공을 실시한다. 이때 롤링, 슬리팅, 가공 등의 공정은 필요에 따라 실시하는 것으로, 생략가능한 공정이다.When the nonwoven fabric is manufactured as described above, it is subjected to rolling, slitting according to the standard, and processing such as perforation and folding. At this time, processes such as rolling, slitting, processing, etc. are carried out as necessary, and may be omitted.

다음으로, 상기 부직포에 pH 2.2~2.9의 산용액을 투입하여 상기 부직포 내에 포함된 키토산을 녹임으로써 겔화한다. 이때 상기 부직포를 1차 포장한 후 산용액을 투입할 수도 있고, 포장이 아닌 별도의 용기에 투입 후 산용액을 투입한 후, 최종 단계에서 포장할 수도 있다. 그리고 상기 산용액의 투입량은 제한하지 않는 데, 부피비로서 부직포와 산용액의 비가 1:1~20 정도로 할 수 있으나, 이를 반드시 제한하는 것은 아니다.Next, an acid solution having a pH of 2.2 to 2.9 is added to the nonwoven fabric to gel the chitosan contained in the nonwoven fabric. At this time, the acid solution may be added after the primary packaging of the nonwoven fabric, or after the acid solution is added to a separate container, the packaging may be packaged in a final step. The amount of the acid solution is not limited, but the ratio of the nonwoven fabric and the acid solution may be about 1: 1-20 as the volume ratio, but is not necessarily limited thereto.

여기서 상기 pH 2.2~2.9의 산용액은 원료의 칭량 또는 혼합, 부직포의 성형단계 시 먼저 제조해두는 것이 공정의 순서상 바람직하나, 이를 제한하지 않는다.Wherein the acid solution of pH 2.2 ~ 2.9 is preferably prepared in the step of weighing or mixing the raw material, the first step of forming the nonwoven fabric in the process, but not limited thereto.

상기 산용액의 제조는 물 또는 마스크 팩용 에센스에 아스코르브산 또는 구연산을 투입하여 그 pH가 2.2~2.9가 되도록 하는 것이다. 상기 액상의 선택은 제조되는 제품의 활용에 따라 달라지는 데, 붕대, 거즈 등으로 사용할 경우 물에 아스코르브산 또는 구연산을 투입하고, 마스크 팩으로 사용할 경우 마스크 팩용 에센스(통상 사용되는 것)에 산을 투입하여 제조한다. 또한 이외에도 창상치료제 등으로 사용될 경우 치료액에 산을 투입하여 제조할 수도 있음은 물론이다.The acid solution is prepared by adding ascorbic acid or citric acid to an essence for water or mask pack so that its pH is 2.2 to 2.9. The choice of the liquid phase depends on the utilization of the product to be prepared. In case of use as a bandage, gauze, etc., ascorbic acid or citric acid is added to water, and when used as a mask pack, an acid is added to an essence for a mask pack (usually used). To prepare. In addition, when used as a wound treatment, etc., it can also be prepared by adding acid to the treatment solution.

이때 상기 pH를 2.2~2.9가 되도록 하는 이유는 상기 pH가 2.9를 초과할 경우 키토산의 겔화가 진행되지 않고 pH가 2.2 미만일 경우 산이 필요 이상으로 과다 투입되기 때문에 경제성 등이 좋지 못하기 때문이다.The reason for the pH to be 2.2 to 2.9 is because the gelation of chitosan does not proceed when the pH exceeds 2.9, and when the pH is less than 2.2, since the acid is excessively added, the economy is not good.

상기 산의 투입량은 pH를 측정하면서 결정하는 데, 일실시 예로서 본 발명에서 정제수에 산을 첨가하면서 pH를 측정한 결과는 하기 표 1과 같았다.The amount of the acid was determined while measuring the pH. As an example, the result of measuring the pH while adding the acid to the purified water was as shown in Table 1 below.

산의 농도별 pH값PH value by acid concentration L-Ascorbic AcidL-Ascorbic Acid 구연산 Citric acid 농도density pHpH 농도density pHpH 0.2% SOL0.2% SOL 2.88 2.88 0.08% SOL0.08% SOL 2.602.60 0.5% SOL0.5% SOL 2.702.70 0.1% SOL0.1% SOL 2.51 2.51 1% SOL1% SOL 2.52 2.52 0.5% SOL0.5% SOL 2.202.20

상기 표 1은 순수 정제수와 SOL반응을 나타낸 것으로 에센스나 액상의 종류에 따라 농도별 pH값은 변할 수 있다. 따라서 에센스 및 액상 종류에 따라 투입량을 조절 pH값을 적절히 조절하도록 한다.Table 1 shows the pure water and the SOL reaction, the pH value of each concentration may vary depending on the type of essence or liquid. Therefore, according to the essence and type of liquid, the adjusted pH value to be adjusted appropriately.

다음으로 상기 키토산을 겔화한 후, 필요에 따라 이를 중화제로 중화할 수 있다. 상기 중화는 본 발명의 부직포가 적용되는 분야에 따라 결정할 사항으로서 생략가능함은 당연하다. 이때 사용되는 중화제 원료로는 무수탄산칼륨(potassium carbonate)을 사용하도록 하고 의약(외)품, 화장품, 식품에 안정되게 사용되어 지는 어떠한 염기성 중화제여도 상관이 없다. 중화방법은 제품별 특성에 따라 방법에 제한을 두지 않는다.Next, after gelling the chitosan, it may be neutralized with a neutralizing agent if necessary. Naturally, the neutralization may be omitted as a matter to be determined according to the field to which the nonwoven fabric of the present invention is applied. At this time, as an ingredient of the neutralizing agent, anhydrous potassium carbonate may be used, and any basic neutralizing agent which is stably used in pharmaceuticals, cosmetics, and foods may be used. The neutralization method does not limit the method depending on the characteristics of each product.

여기서, 상기 중화단계는 앞서 산에 의해 키토산이 충분히 녹을 수 있을 정도의 시간을 부여한 후 적용하는 것으로, 적어도 산처리 후 5분이 지나면 실시한다.In this case, the neutralization step is applied after giving a time enough to dissolve the chitosan sufficiently by the acid, at least 5 minutes after the acid treatment.

또한 상기 중화를 통한 pH는 5.5~6.0가 되는 것이 바람직하나 이를 반드시 제한하는 것은 아니다. In addition, the pH through the neutralization is preferably 5.5 to 6.0, but is not necessarily limited thereto.

그리고, 최종적으로 제조된 부직포를 실링 및 포장한다.Then, the finally produced nonwoven fabric is sealed and packaged.

본 발명에서 상기와 같이 제조된 기능성 부직포는, 부직포 내에 키토산이 겔화된 상태로 있기 때문에 키토산으로 인하여 부직포의 질감이 뻣뻣해지는 것을 방지할 수 있고, 이로 인해 키토산을 종래의 방법에 비하여 다량 투입할 수 있게 되는 것이다.In the present invention, the functional nonwoven fabric prepared as described above can prevent the stiffness of the nonwoven fabric due to chitosan because the chitosan is gelled in the nonwoven fabric, so that chitosan can be added in a large amount compared to the conventional method. Will be.

따라서 많은 량의 키토산을 투입할 수 있고, 겔화된 키토산이 피부에 직접적으로 작용할 수 있게 되므로, 키토산의 재생력, 보습력, 항균력, 상처치유력 등의 기능을 충분히 활용할 수 있게 된다.Therefore, a large amount of chitosan can be added, and the gelled chitosan can act directly on the skin, thereby fully utilizing the functions of the regeneration, moisturizing, antibacterial, and wound healing of chitosan.

그리고, 앞서 설명한 바와 같이 본 발명의 부직포는 마스크팩, 의약외품 등에 사용될 수 있을 뿐 아니라, 부직포가 적용될 수 있는 모든 분야에 활용할 수 있는 제품으로서, 그 활용을 제한하지 않는다.In addition, as described above, the nonwoven fabric of the present invention may be used in mask packs, quasi-drugs, and the like, and is a product that can be used in all fields to which the nonwoven fabric can be applied.

본 발명은 상술한 특정의 실시예 및 설명에 한정되지 아니하며, 청구범위에서 청구하는 본 발명의 요지를 벗어남이 없이 당해 발명이 속하는 기술 분야에서 통상의 지식을 가진 자라면 누구든지 다양한 변형 실시가 가능하며, 그와 같은 변형은 본 발명의 보호 범위 내에 있게 된다.The present invention is not limited to the above-described specific embodiments and descriptions, and various modifications can be made to those skilled in the art without departing from the gist of the present invention claimed in the claims. And such modifications are within the scope of protection of the present invention.

Claims (9)

부직포를 구성함에 있어서,
상기 부직포는 키토산 섬유와 면 섬유가 혼합되어 이루어지되,
상기 키토산 섬유의 키토산은 겔화된 상태인 것을 특징으로 하는 키토산을 이용한 기능성 부직포.In constructing the nonwoven fabric,
The nonwoven fabric is made of a mixture of chitosan fibers and cotton fibers,
Functional nonwoven fabric using chitosan, characterized in that the chitosan of the chitosan fiber is in a gelled state. 제 1항에 있어서,
상기 키토산은 산에 의해 겔화된 것을 특징으로 하는 키토산을 이용한 기능성 부직포.The method of claim 1,
The chitosan is a functional nonwoven fabric using chitosan, characterized in that gelled with acid. 제 2항에 있어서,
상기 산은 아스코르브산 또는 구연산인 것을 특징으로 하는 키토산을 이용한 기능성 부직포.The method of claim 2,
Functional acid nonwoven fabric using chitosan, characterized in that the acid is ascorbic acid or citric acid. 제 1항 내지 제 3항 중 어느 한 항에 있어서,
상기 부직포는 키토산 섬유 20~60중량%와 면 섬유 40~80중량%가 혼합되어 이루어지는 것을 특징으로 하는 키토산을 이용한 기능성 부직포.4. The method according to any one of claims 1 to 3,
The nonwoven fabric is a functional nonwoven fabric using chitosan, characterized in that 20 to 60% by weight of chitosan fibers and 40 to 80% by weight of cotton fibers are mixed. 제 4항에 있어서,
상기 부직포는 마스크 팩, 거즈, 붕대 및 창상치료제 중 어느 하나에 사용되는 것을 특징으로 하는 키토산을 이용한 기능성 부직포.5. The method of claim 4,
The nonwoven fabric is a functional nonwoven fabric using chitosan, characterized in that used in any one of a mask pack, gauze, bandages and wound treatment. 키토산 섬유와 면 섬유를 혼합하는 단계와,
상기 혼합된 키토산 섬유와 면 섬유를 카딩 및 워터펀칭하여 부직포로 제조하는 단계와,
상기 부직포에 pH 2.2~2.9의 산용액을 투입하여 상기 부직포 내에 포함된 키토산을 겔화하는 단계를 포함하여 이루어지는 것을 특징으로 하는 키토산을 이용한 기능성 부직포의 제조방법.Mixing chitosan fibers and cotton fibers,
Carding and water punching the mixed chitosan fibers and cotton fibers to produce a nonwoven fabric;
Method of producing a functional nonwoven fabric using chitosan, comprising the step of gelling chitosan contained in the nonwoven fabric by adding an acid solution of pH 2.2 ~ 2.9 to the nonwoven fabric. 제 6항에 있어서,
상기 산용액은 물 또는 마스크 팩용 에센스에 아스코르브산 또는 구연산을 투입하여 이루어지는 것을 특징으로 하는 키토산을 이용한 기능성 부직포의 제조방법.The method according to claim 6,
The acid solution is a method for producing a functional nonwoven fabric using chitosan, characterized in that ascorbic acid or citric acid is added to the essence for water or mask pack. 제 6항에 있어서,
상기 부직포는 키토산 섬유 20~60중량%와 면 섬유 40~80중량%가 혼합되어 이루어지는 것을 특징으로 하는 키토산을 이용한 기능성 부직포의 제조방법.The method according to claim 6,
The nonwoven fabric is a method for producing a functional nonwoven fabric using chitosan, characterized in that 20 to 60% by weight of chitosan fibers and 40 to 80% by weight of cotton fibers are mixed. 제 6항 내지 제 8항 중 어느 한 항에 있어서,
상기 키토산을 겔화하는 단계 후, 이를 중화제로 pH 5.5~6.0으로 중화하는 단계를 더 포함하는 것을 특징으로 하는 키토산을 이용한 기능성 부직포의 제조방법.9. The method according to any one of claims 6 to 8,
After the step of gelling the chitosan, neutralizing it to pH 5.5 ~ 6.0 with a neutralizing agent further comprising the step of producing a functional nonwoven fabric using chitosan.
KR1020120051933A 2012-05-16 2012-05-16 Functional non-woven fabric using chitosan and manufacturing method therof KR101329261B1 (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101736124B1 (en) * 2015-06-19 2017-05-18 (주)케이엘코퍼레이션 Manufacturing method of non woven fabric using chitosan, and use of thereof
KR101747674B1 (en) * 2015-07-03 2017-06-15 윤용만 A mask-pack sheet with bamboo carbon fiber and chitosan fiber
US20180014975A1 (en) * 2015-01-27 2018-01-18 Medtrade Products Limited Composition for a wound dressing
KR101936879B1 (en) 2017-02-06 2019-01-11 주식회사 인코아 Medical fibrous structure comprising chitosan and Manufacturing method of medical fibrous structure thereby
KR102052921B1 (en) * 2018-09-13 2020-01-08 조석형 Anti-bacterial chitosan non-woven fabric and maskpack

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010097226A (en) * 2000-04-20 2001-11-08 이신희 A method of preparing chitosan non-woven fabric of softness and flexibility for medical care
US20090287130A1 (en) 2008-05-08 2009-11-19 Convatec Technologies Inc.. Wound dressing
KR20110074006A (en) * 2009-12-24 2011-06-30 한국생산기술연구원 Surgical nonwoven material and manufacturing method thereof
KR20120033393A (en) * 2010-09-30 2012-04-09 (주)크론바이오 Hydrogel pack using chitosan and method of preparing the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010097226A (en) * 2000-04-20 2001-11-08 이신희 A method of preparing chitosan non-woven fabric of softness and flexibility for medical care
US20090287130A1 (en) 2008-05-08 2009-11-19 Convatec Technologies Inc.. Wound dressing
KR20110074006A (en) * 2009-12-24 2011-06-30 한국생산기술연구원 Surgical nonwoven material and manufacturing method thereof
KR20120033393A (en) * 2010-09-30 2012-04-09 (주)크론바이오 Hydrogel pack using chitosan and method of preparing the same

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180014975A1 (en) * 2015-01-27 2018-01-18 Medtrade Products Limited Composition for a wound dressing
US10561533B2 (en) * 2015-01-27 2020-02-18 Medtrade Products Limited Composition for a wound dressing
US20200197225A1 (en) * 2015-01-27 2020-06-25 Medtrade Products Limited Composition for a wound dressing
US10973691B2 (en) 2015-01-27 2021-04-13 Medtrade Products Limited Composition for a wound dressing
KR101736124B1 (en) * 2015-06-19 2017-05-18 (주)케이엘코퍼레이션 Manufacturing method of non woven fabric using chitosan, and use of thereof
KR101747674B1 (en) * 2015-07-03 2017-06-15 윤용만 A mask-pack sheet with bamboo carbon fiber and chitosan fiber
KR101936879B1 (en) 2017-02-06 2019-01-11 주식회사 인코아 Medical fibrous structure comprising chitosan and Manufacturing method of medical fibrous structure thereby
KR102052921B1 (en) * 2018-09-13 2020-01-08 조석형 Anti-bacterial chitosan non-woven fabric and maskpack

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