KR101122495B1 - 통증, 특히 통각과민의 치료를 위한스퐁고신（2-메톡시아데노세인）의 용도 - Google Patents

통증, 특히 통각과민의 치료를 위한스퐁고신（2-메톡시아데노세인）의 용도 Download PDF

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KR101122495B1
KR101122495B1 KR1020057010441A KR20057010441A KR101122495B1 KR 101122495 B1 KR101122495 B1 KR 101122495B1 KR 1020057010441 A KR1020057010441 A KR 1020057010441A KR 20057010441 A KR20057010441 A KR 20057010441A KR 101122495 B1 KR101122495 B1 KR 101122495B1
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pain
spongosine
treatment
medicament
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KR20050089815A (ko
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피터 리처드슨
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캠브리지 바이오테크놀로지 리미티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020057010441A 2002-12-09 2003-12-09 통증, 특히 통각과민의 치료를 위한스퐁고신（2-메톡시아데노세인）의 용도 Expired - Fee Related KR101122495B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0228723.3 2002-12-09
GBGB0228723.3A GB0228723D0 (en) 2002-12-09 2002-12-09 Treatment of pain
PCT/GB2003/005379 WO2004052377A1 (en) 2002-12-09 2003-12-09 Use of spongosine (2-methoxyadenosein) for the treatment of pain, in particular hyperalgesia

Publications (2)

Publication Number Publication Date
KR20050089815A KR20050089815A (ko) 2005-09-08
KR101122495B1 true KR101122495B1 (ko) 2012-03-15

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KR1020057010441A Expired - Fee Related KR101122495B1 (ko) 2002-12-09 2003-12-09 통증, 특히 통각과민의 치료를 위한스퐁고신（2-메톡시아데노세인）의 용도

Country Status (18)

Country Link
US (2) US8252766B2 (enExample)
EP (1) EP1581235B1 (enExample)
JP (2) JP4836454B2 (enExample)
KR (1) KR101122495B1 (enExample)
CN (2) CN101264097B (enExample)
AT (1) ATE430572T1 (enExample)
AU (1) AU2003288451B2 (enExample)
CA (1) CA2507918A1 (enExample)
CY (1) CY1109229T1 (enExample)
DE (1) DE60327557D1 (enExample)
DK (1) DK1581235T3 (enExample)
ES (1) ES2326532T3 (enExample)
GB (2) GB0228723D0 (enExample)
NO (1) NO20053042L (enExample)
NZ (1) NZ540353A (enExample)
PT (1) PT1581235E (enExample)
SI (1) SI1581235T1 (enExample)
WO (1) WO2004052377A1 (enExample)

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GB0305149D0 (en) * 2003-03-07 2003-04-09 Cambridge Biotechnology Ltd Compounds for the treatment of pain
WO2005084653A2 (en) * 2004-03-05 2005-09-15 Cambridge Biotechnology Limited Adenosine receptor agonists
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
US8603779B2 (en) 2004-12-01 2013-12-10 Syntaxin, Ltd. Non-cytotoxic protein conjugates
US8778634B2 (en) 2004-12-01 2014-07-15 Syntaxin, Ltd. Non-cytotoxic protein conjugates
US8512984B2 (en) 2004-12-01 2013-08-20 Syntaxin, Ltd. Non-cytotoxic protein conjugates
US8399400B2 (en) 2004-12-01 2013-03-19 Syntaxin, Ltd. Fusion proteins
GB0426394D0 (en) * 2004-12-01 2005-01-05 Health Prot Agency Fusion proteins
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
GB0610867D0 (en) 2006-06-01 2006-07-12 Syntaxin Ltd Treatment of pain
EP2081932A2 (en) 2006-06-27 2009-07-29 BIOVITRUM AB (publ) 2-o'-methyladenosine derivatives and their use as agonists or antagonists of an adenosine receptor
CA2657973A1 (en) 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Therapeutic compounds
JP2009541438A (ja) * 2006-06-27 2009-11-26 ビオヴィトルム・アクチボラゲット（プブリクト） 治療用化合物
US20090181920A1 (en) * 2008-01-09 2009-07-16 Pgxhealth, Llc Intrathecal treatment of neuropathic pain with a2ar agonists
US8221791B1 (en) 2008-12-10 2012-07-17 University Of Central Florida Research Foundation, Inc. Silica-based antibacterial and antifungal nanoformulation
CA2766937A1 (en) * 2009-07-09 2011-01-13 Cbt Development Limited Combined preparation for use as a medicament
WO2011143442A1 (en) * 2010-05-12 2011-11-17 Trovis Pharmaceuticals, Llc. A method of treating multiple sclerosis with adenosine receptor agonists
EP2631345B1 (en) * 2012-02-27 2019-09-04 Electrolux Home Products Corporation N.V. Washing tub unit and washing machine
US20140056870A1 (en) 2012-08-27 2014-02-27 Allergan, Inc. Fusion proteins
CN113999281A (zh) * 2016-02-04 2022-02-01 约翰霍普金斯大学 平衡型核苷转运蛋白1的抑制剂Rapadocin及其用途

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JPS5461195A (en) * 1977-10-21 1979-05-17 Takeda Chem Ind Ltd N2-substituted phenyl-2,6-diaminonebularin
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Also Published As

Publication number Publication date
CN101264097A (zh) 2008-09-17
GB0228723D0 (en) 2003-01-15
GB2396108A (en) 2004-06-16
CN100471503C (zh) 2009-03-25
CA2507918A1 (en) 2004-06-24
EP1581235A1 (en) 2005-10-05
SI1581235T1 (sl) 2009-10-31
AU2003288451A1 (en) 2004-06-30
DE60327557D1 (de) 2009-06-18
JP2011132229A (ja) 2011-07-07
KR20050089815A (ko) 2005-09-08
GB2396108B (en) 2005-08-03
US20070010475A1 (en) 2007-01-11
JP4836454B2 (ja) 2011-12-14
AU2003288451B2 (en) 2009-06-04
JP2006514638A (ja) 2006-05-11
WO2004052377A1 (en) 2004-06-24
CN101264097B (zh) 2011-10-05
ATE430572T1 (de) 2009-05-15
HK1086186A1 (zh) 2006-09-15
GB0328548D0 (en) 2004-01-14
CN1723026A (zh) 2006-01-18
PT1581235E (pt) 2009-07-07
DK1581235T3 (da) 2009-08-31
US8252766B2 (en) 2012-08-28
EP1581235B1 (en) 2009-05-06
US20110184065A1 (en) 2011-07-28
ES2326532T3 (es) 2009-10-14
NZ540353A (en) 2006-11-30
CY1109229T1 (el) 2013-09-04
NO20053042L (no) 2005-06-21

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