KR101105349B1 - Method of decomposing antibacterial agents by vacuum ultraviolet - Google Patents
Method of decomposing antibacterial agents by vacuum ultraviolet Download PDFInfo
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- KR101105349B1 KR101105349B1 KR1020080101931A KR20080101931A KR101105349B1 KR 101105349 B1 KR101105349 B1 KR 101105349B1 KR 1020080101931 A KR1020080101931 A KR 1020080101931A KR 20080101931 A KR20080101931 A KR 20080101931A KR 101105349 B1 KR101105349 B1 KR 101105349B1
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- 239000003242 anti bacterial agent Substances 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 title claims abstract description 35
- 229940088710 antibiotic agent Drugs 0.000 claims abstract description 41
- 239000002351 wastewater Substances 0.000 claims abstract description 32
- 230000003115 biocidal effect Effects 0.000 claims abstract description 29
- 238000000354 decomposition reaction Methods 0.000 claims abstract description 24
- 239000006227 byproduct Substances 0.000 claims abstract description 15
- 239000010794 food waste Substances 0.000 claims abstract description 15
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- -1 servings Substances 0.000 claims abstract description 14
- 230000005855 radiation Effects 0.000 claims abstract description 10
- 239000010842 industrial wastewater Substances 0.000 claims abstract description 8
- 238000009264 composting Methods 0.000 claims abstract description 7
- 230000001678 irradiating effect Effects 0.000 claims abstract description 7
- 239000010802 sludge Substances 0.000 claims abstract description 7
- 238000003912 environmental pollution Methods 0.000 claims abstract description 4
- OJMMVQQUTAEWLP-UHFFFAOYSA-N Lincomycin Natural products CN1CC(CCC)CC1C(=O)NC(C(C)O)C1C(O)C(O)C(O)C(SC)O1 OJMMVQQUTAEWLP-UHFFFAOYSA-N 0.000 claims description 5
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 claims description 5
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 claims description 5
- OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 claims description 5
- 229960005287 lincomycin Drugs 0.000 claims description 5
- 239000002361 compost Substances 0.000 claims description 4
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims description 2
- 229910052753 mercury Inorganic materials 0.000 claims description 2
- 239000010801 sewage sludge Substances 0.000 abstract description 7
- 231100000419 toxicity Toxicity 0.000 abstract description 4
- 230000001988 toxicity Effects 0.000 abstract description 4
- 229910019142 PO4 Inorganic materials 0.000 abstract description 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract description 3
- 239000010452 phosphate Substances 0.000 abstract description 3
- 231100000614 poison Toxicity 0.000 abstract description 3
- 239000003440 toxic substance Substances 0.000 abstract description 3
- 230000035800 maturation Effects 0.000 abstract description 2
- 239000003344 environmental pollutant Substances 0.000 description 9
- 230000015556 catabolic process Effects 0.000 description 8
- 238000006731 degradation reaction Methods 0.000 description 8
- 239000007864 aqueous solution Substances 0.000 description 7
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- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 4
- 239000004098 Tetracycline Substances 0.000 description 4
- 239000004599 antimicrobial Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000010865 sewage Substances 0.000 description 4
- 229960002180 tetracycline Drugs 0.000 description 4
- 229930101283 tetracycline Natural products 0.000 description 4
- 235000019364 tetracycline Nutrition 0.000 description 4
- 150000003522 tetracyclines Chemical class 0.000 description 4
- 238000006065 biodegradation reaction Methods 0.000 description 3
- 230000002070 germicidal effect Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 244000144972 livestock Species 0.000 description 3
- 229960005404 sulfamethoxazole Drugs 0.000 description 3
- JLKIGFTWXXRPMT-UHFFFAOYSA-N sulphamethoxazole Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 JLKIGFTWXXRPMT-UHFFFAOYSA-N 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
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- 239000011941 photocatalyst Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- IEDVJHCEMCRBQM-UHFFFAOYSA-N trimethoprim Chemical compound COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 IEDVJHCEMCRBQM-UHFFFAOYSA-N 0.000 description 2
- 229960001082 trimethoprim Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- WZRJTRPJURQBRM-UHFFFAOYSA-N 4-amino-n-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine Chemical compound O1C(C)=CC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1.COC1=C(OC)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 WZRJTRPJURQBRM-UHFFFAOYSA-N 0.000 description 1
- 229930186147 Cephalosporin Natural products 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 229910010413 TiO 2 Inorganic materials 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 229940126575 aminoglycoside Drugs 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 229940124587 cephalosporin Drugs 0.000 description 1
- 150000001780 cephalosporins Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical class ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 150000004678 hydrides Chemical class 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 239000003120 macrolide antibiotic agent Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000001089 mineralizing effect Effects 0.000 description 1
- 238000007539 photo-oxidation reaction Methods 0.000 description 1
- 238000006552 photochemical reaction Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000013341 scale-up Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
- 238000004065 wastewater treatment Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/30—Treatment of water, waste water, or sewage by irradiation
- C02F1/32—Treatment of water, waste water, or sewage by irradiation with ultraviolet light
- C02F1/325—Irradiation devices or lamp constructions
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F3/00—Biological treatment of water, waste water, or sewage
- C02F3/02—Aerobic processes
- C02F3/12—Activated sludge processes
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
- C02F2201/002—Construction details of the apparatus
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
- C02F2201/32—Details relating to UV-irradiation devices
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- Water Supply & Treatment (AREA)
- Hydrology & Water Resources (AREA)
- Engineering & Computer Science (AREA)
- Environmental & Geological Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Health & Medical Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- Microbiology (AREA)
- Treatment Of Sludge (AREA)
- Physical Water Treatments (AREA)
Abstract
본 발명은 진공자외선을 이용한 항생제의 분해방법에 관한 것으로, 더욱 상세하게는 항생제가 함유된 하폐수, 하폐수 슬러지, 제약 폐수, 산업 폐수, 인분, 가축분뇨 및 음식물 쓰레기로 이루어지는 군으로부터 선택되는 환경 오염처리 부산물에 진공자외선을 조사하는 단계를 포함하는 진공자외선을 이용한 항생제의 분해방법에 관한 것이다. 본 발명에 따른 항생제 분해방법은 항생제가 가지고 있는 독성뿐 아니라 생물체에 유발되는 내성을 제거할 수 있으며, 난분해성 유기독성물질로 알려진 항생제를 진공자외선 조사 기술을 이용하여 분해시킴으로써 하폐수, 제약폐수, 산업폐수의 생물학적 처리 효율을 극대화시킬 수 있으며, 또한 축산분뇨, 인분, 하폐수 슬러지 또는 음식물 쓰레기의 퇴비화 및 사료화 과정에서 생물학적 부숙을 가능하게 한다.The present invention relates to a method for decomposing antibiotics using vacuum ultraviolet rays, and more specifically, to environmental pollution treatment selected from the group consisting of antibiotic-containing wastewater, wastewater sludge, pharmaceutical wastewater, industrial wastewater, servings, livestock manure and food waste. The present invention relates to a method for decomposing antibiotics using vacuum ultraviolet radiation, comprising irradiating vacuum by-products to vacuum by-products. The antibiotic decomposition method according to the present invention can remove not only the toxicity of antibiotics, but also the resistance caused to organisms, and decomposes antibiotics known as non-degradable organic toxic substances by using vacuum ultraviolet irradiation technology to treat wastewater, pharmaceutical wastewater, and industry. It is possible to maximize the biological treatment efficiency of wastewater, and also to enable biological maturation in the composting and feeding process of livestock manure, phosphate, sewage sludge or food waste.
진공자외선, 항생제, 항균제, 항생제 분해 Ultraviolet rays, antibiotics, antibacterial agents, antibiotic decomposition
Description
본 발명은 자연생태계 및 환경오염물질 처리 부산물 중에 존재하는 다양한 항생제를 진공자외선 조사를 통하여 분해하는 방법에 관한 것이다.The present invention relates to a method for decomposing various antibiotics present in natural ecosystems and by-products of environmental pollutants through vacuum ultraviolet irradiation.
최근 항생제는 인체에 투여하는 것뿐만 아니라 가축 사료 등에 포함되어 다량이 공급되고 있어서, 항생제가 함유된 하폐수, 하폐수 슬러지, 인분, 가축분뇨 또는 음식물 쓰레기들이 자연 생태계에 그대로 노출되고 있으며, 특히 노출된 항생제에 의해서 유발된 항생제 내성 유전자가 각종 미생물에 전이가 되어 결과적으로 인간에게 치명적인 위협이 되기 때문에 사회적 문제로 대두되고 있는 상황이다. Recently, antibiotics are not only administered to the human body, but are also supplied in large quantities in livestock feeds, so that wastewater containing sewage, sewage sludge, serving, livestock manure or food waste containing antibiotics are exposed to natural ecosystems. Antibiotic-resistant genes caused by E. coli are transferred to various microorganisms, resulting in a fatal threat to humans.
그러나 자연생태계에 최종 배출되는 항생제는 국내외에서 방류수 기준항목에 포함되어 있지 않은바, 그 제거 기술의 개발은 극히 미미한 수준이며, 또한 항생제 등은 그 화학적 구조가 안정하여 분해하기도 어려울 뿐만 아니라 분해한다 하여도 각종 독성 물질로 전환될 가능성이 있기 때문에 분해의 어려움이 있다.However, antibiotics that are finally discharged into the natural ecosystem are not included in the effluent standard items at home and abroad, and the development of their removal technology is very minimal. Also, antibiotics are difficult to decompose due to their stable chemical structure and decompose. In addition, since there is a possibility of conversion to various toxic substances, there is a difficulty in decomposition.
특히 국내에서는 특정 항생제 처리에 관한 연구는 거의 이루어 지지 않고 있으며, 국외에서도 자연생태계에 잔류하는 항생제를 측정하고 기존 하수처리장의 생물학적 분해에 미치는 영향과 자연적인 광화학반응을 연구하는 정도이며, 특히 인분, 가축분뇨 또는 음식물 쓰레기 등은 퇴비화 및 사료화 과정에서 항생제의 독성으로 인하여 생물학적 부숙이 어렵기 때문에 자원의 재활용이라는 측면에서도 한계가 있는 상황이다.In particular, there is little research on the treatment of specific antibiotics in Korea, and it is the degree to measure the antibiotics remaining in the natural ecosystem and study the effects on the biodegradation of existing sewage treatment plants and natural photochemical reactions. Livestock manure or food waste is also limited in terms of recycling resources because it is difficult to biologically mature due to the toxicity of antibiotics during composting and feed.
종래 항생제 또는 항균제 분해방법에 있어서는 일본공개공보 제2004-74119호에서 의약품 및 의약외품에 오염된 물에 방사선을 오존의 존재하에 직접 조사하는 것에 의하여 이들을 분해 처리하는 것을 특징으로 하는 방법이 개시되어 있으나, 상기 방법은 방사선에 의하여 발생한 라디칼이 항균제를 무해한 화합물로 분해하기 보다는 라디칼이 화학결합을 촉진하여 올리고머 또는 고분자량의 폴리머를 형성하는 반응이 더 우세하게 진행되는 단점이 있어 상용화에는 한계가 있다.In the conventional method for decomposing antibiotics or antimicrobials, Japanese Laid-Open Patent Publication No. 2004-74119 discloses a method of decomposing these substances by directly irradiating water contaminated with medicines and quasi-drugs in the presence of ozone. The method has a disadvantage in that the radicals generated by the radiation decompose the antimicrobial agent into harmless compounds, so that the radicals promote the chemical bonds to form oligomers or high molecular weight polymers, and thus the commercialization is limited.
이를 개선하기 위하여, 대한민국 특허등록 제601113호에서는 항균제가 함유된 환경오염물질 처리 부산물에 N2O를 첨가한 후 방사선을 조사하여 항균제를 분해하는 방법이 개시되어 있다. 그러나 방사선 기술을 사용하기 위해서는 차폐를 해야 하는데, 이때 초기 설치비용이 많이 들며 설치가 용이하지 않은 문제가 있다.In order to improve this, Korean Patent Registration No. 601113 discloses a method of decomposing an antimicrobial agent by irradiating with radiation after adding N 2 O to an environmental pollutant by-product containing an antimicrobial agent. However, in order to use radiation technology, shielding is required, and there is a problem that the initial installation cost is high and the installation is not easy.
이에, 본 발명자들은 자연생태계 및 환경오염물질 처리 부산물 중에 존재하 는 항생제를 용이하게 분해시킬 수 있으며, 설치가 용이하고 경제적인 방법을 연구하던 중, 진공자외선 조사를 이용할 때 상기 문제를 해결할 수 있음을 알아내고 본 발명을 완성하였다.Accordingly, the present inventors can easily decompose antibiotics present in natural ecosystems and environmental pollutant treatment by-products, and can solve the above problems when using vacuum ultraviolet irradiation while studying an easy and economical method. The present invention was completed.
본 발명의 목적은 진공자외선 조사방법을 이용하여 자연 생태계에 잔류하거나 기존의 환경처리기술 적용 후 존재할 수 있는 항생제를 분해 및 무기화(無機化, mineralization) 시키거나 독성을 제거하여 기존 하폐수 처리 시설의 생물학적 분해 효율을 극대화 시키는 방법을 제공하는 데 있다. It is an object of the present invention to decompose and mineralize antibiotics that may remain in a natural ecosystem or to exist after application of existing environmental treatment techniques using vacuum ultraviolet irradiation, and to remove toxicities, thereby removing the biological effects of existing wastewater treatment facilities. It is to provide a method for maximizing the decomposition efficiency.
본 발명의 다른 목적은 진공자외선 조사에 의하여 항생제를 분해함으로써 하폐수, 제약폐수 및 여타 산업폐수의 생물학적 분해공정과, 축산분뇨, 인분, 하폐수 슬러지 및 음식물 쓰레기의 퇴비화 및 사료화 과정에서 생물학적 부숙이 가능하도록 하는 방법을 제공하는 데 있다.It is another object of the present invention to decompose antibiotics by vacuum ultraviolet radiation so that biodegradation of wastewater, pharmaceutical wastewater and other industrial wastewater and biological composting of livestock manure, phosphate, sewage sludge and food waste are possible. To provide a way.
본 발명의 또 다른 목적은 상기 항생제의 분해방법에 의해 처리된 퇴비 및 사료를 제공하는 데 있다.Another object of the present invention is to provide a compost and feed treated by the decomposition method of the antibiotic.
상기 목적을 달성하기 위하여 본 발명은 항생제가 함유된 하폐수, 하폐수 슬러지, 인분, 가축분뇨 또는 음식물 쓰레기에 진공자외선(VUV)을 조사하는 단계를 포함하는 진공자외선을 이용한 항생제의 분해방법을 제공한다.In order to achieve the above object, the present invention provides a method for decomposing antibiotics using vacuum ultraviolet rays, which comprises irradiating vacuum ultraviolet (VUV) to wastewater, wastewater sludge, servings, livestock manure or food waste containing antibiotics.
또한 본 발명은 하폐수, 하폐수 슬러지, 인분, 가축분뇨 또는 음식물 쓰레기를 상기 항생제의 분해방법에 의해 처리하고, 생물학적 처리에 의하여 퇴비화 및 사료화하는 방법을 제공한다.The present invention also provides a method for treating sewage, sewage sludge, serving, livestock manure or food waste by the decomposition method of the antibiotic, composting and feed by biological treatment.
나아가, 본 발명은 상기 항생제의 분해방법에 의해 처리된 퇴비 및 사료를 제공한다.Furthermore, the present invention provides a compost and feed treated by the decomposition method of the antibiotic.
본 발명에 따른 항생제 분해방법은 항생제가 가지고 있는 독성뿐 아니라 생물체에 유발되는 내성을 제거할 수 있으며, 난분해성 유기독성물질로 알려진 항생제를 진공자외선 조사 기술을 이용하여 분해시킴으로써 하폐수, 제약폐수, 산업폐수의 생물학적 처리 효율을 극대화시킬 수 있으며, 또한 축산분뇨, 인분, 하폐수 슬러지 또는 음식물 쓰레기의 퇴비화 및 사료화 과정에서 생물학적 부숙을 가능하게 한다.The antibiotic decomposition method according to the present invention can remove not only the toxicity of antibiotics, but also the resistance caused to organisms, and decomposes antibiotics known as non-degradable organic toxic substances by using vacuum ultraviolet irradiation technology to treat wastewater, pharmaceutical wastewater, and industry. It is possible to maximize the biological treatment efficiency of wastewater, and also to enable biological maturation in the composting and feeding process of livestock manure, phosphate, sewage sludge or food waste.
이하, 본 발명을 상세하게 설명한다.EMBODIMENT OF THE INVENTION Hereinafter, this invention is demonstrated in detail.
본 발명은 자연생태계 및 환경오염물질 처리 부산물 중에 존재하는 다양한 항생제를 진공자외선 조사를 통하여 분해하는 방법을 제공한다.The present invention provides a method for decomposing various antibiotics present in natural ecosystems and environmental pollutant treatment by-products by vacuum ultraviolet irradiation.
본 발명에 따른 항생제 분해방법에 있어서, 상기 환경오염물질 처리 부산물로는 하폐수, 하폐수 슬러지, 제약 폐수, 산업 폐수, 인분, 가축분뇨, 음식물 쓰레기 등을 들 수 있으나, 이에 제한되지 않는다. 이러한 환경오염 물질 처리 부산물 내에 포함된 항생제는 진공자외선을 조사함으로써 분해 및 무기화(mineralization) 되거나 독성이 제거되어 생물학적 분해를 극대화시킬 수 있다.In the antibiotic decomposition method according to the present invention, the environmental pollutant treatment by-products include, but are not limited to, sewage, sewage sludge, pharmaceutical wastewater, industrial wastewater, serving, livestock manure, food waste. Antibiotics contained in these by-products of environmental pollutant treatment can be decomposed, mineralized, or toxic removed by irradiation with vacuum ultraviolet rays to maximize biological degradation.
본 발명에 따른 항생제 분해방법에 있어서, 사용되는 진공자외선은 200 nm 이하의 파장을 갖는 것이 바람직하며, 100~200 nm의 파장을 갖는 것을 사용하는 것이 더욱 바람직하다.In the antibiotic decomposition method according to the present invention, it is preferable that the vacuum ultraviolet ray to be used has a wavelength of 200 nm or less, and more preferably, one having a wavelength of 100 to 200 nm.
자외선은 파장에 따라서 UV-A, UV-B, UV-C 및 진공자외선(VUV)로 나눌 수 있다. UV-A는 일반적으로 320~400 nm의 파장을 가지는 자외선을 말하며, 실내에서 선태닝을 하거나 푸른 조명을 할 때 사용된다. 또한 최근에는 TiO2 등의 광촉매가 활성화될 수 있는 에너지원으로 사용할 수 있어 광촉매를 이용한 수처리, 대기처리에 사용되고 있다. UV-B는 일반적으로 280~320 nm의 파장을 가지는 자외선이며, 비타민 D를 형성하거나 피부에 홍반작용을 일으키는 자외선이다. UV-C는 일반적으로 200~280 nm의 파장을 갖는 자외선으로서 살균자외선이라고도 하며, DNA, 단백질 및 오존이 잘 흡수하는 파장이다. 따라서 오존을 잘 분해하기 때문에 최근에는 오존파괴용 및 소독용으로 사용되고 있다. Ultraviolet rays can be divided into UV-A, UV-B, UV-C and vacuum ultraviolet (VUV) depending on the wavelength. UV-A generally refers to ultraviolet rays having a wavelength of 320 to 400 nm, and are used for sun tanning or blue lighting indoors. In addition, recently, photocatalysts such as TiO 2 can be used as energy sources that can be activated, and thus they are used for water treatment and atmospheric treatment using photocatalysts. UV-B is generally ultraviolet rays having a wavelength of 280-320 nm, ultraviolet rays that form vitamin D or cause erythema on the skin. UV-C is generally called ultraviolet rays with a wavelength of 200-280 nm, also called germicidal ultraviolet rays, and is a wavelength absorbed well by DNA, protein and ozone. Therefore, since ozone decomposes well, it has recently been used for ozone depletion and disinfection.
진공자외선은 100~200 nm의 파장을 갖는 자외선으로서 공기에 의해 세게 흡수되기 때문에 진공 속에서만 취급할 수가 있어서 진공자외선이라 한다. 상기 진공자외선은 공기뿐만 아니라 거의 물질에 의해 강하게 흡수되어 물질 속의 전자를 들뜨게 하거나 물질에서 전자를 방출시키기도 한다. 진공자외선을 수용액에 조사하였을 때 직접적인 광산화 반응과 반응식 (1) 및 (2)와 같이 간접적인 수화학적 분해에 의하여 하이드록실 라디칼, 수소 원자, 수화전자 등의 이온성 물질이 생성 되게 되며, 상기 이온성 물질 가운데 하이드록실 라디칼이 처리대상 물질을 무기화하는 데 매우 효과적인 것으로 알려져 있다.Vacuum ultraviolet rays are ultraviolet rays having a wavelength of 100 to 200 nm, and are absorbed strongly by air, so they can only be handled in a vacuum, so vacuum ultraviolet rays are called. The vacuum ultraviolet ray is strongly absorbed by the material as well as air, and may excite electrons in the material or release electrons from the material. When irradiated with vacuum ultraviolet rays in an aqueous solution, ionic substances such as hydroxyl radicals, hydrogen atoms, and hydride electrons are generated by direct photo-oxidation reactions and indirect hydrochemical decomposition as shown in Schemes (1) and (2). Among the active substances, hydroxyl radicals are known to be very effective in mineralizing the material to be treated.
(1) H2O(l) + hv(VUV) → [e-, H2O+] + (H2O)(1) H 2 O (l) + hv (VUV) → [e − , H 2 O + ] + (H 2 O)
(2) [e-, H2O+] + (H2O) → eeq - + HO· + H3O+ (2) [e -, H 2 O +] + (H 2 O) → e eq - + HO · + H 3 O +
본 발명에 따른 항생제 분해방법에 있어서, 방사선 조사 시간은 하폐수, 하폐수 슬러지, 제약 폐수, 산업 폐수, 인분, 가축분뇨, 음식물 쓰레기 등의 환경오염처리 부산물 내에 포함되어 있는 항생제의 함량에 따라 적절하게 조절할 수 있다. 항생제 농도가 낮고 조사선량을 스케일-업(scale-up)시키면 진공자외선에서 생성되는 에너지가 커지므로 5분 이내에서도 항생제의 분해가 가능하다.In the antibiotic decomposition method according to the present invention, the irradiation time is appropriately adjusted according to the amount of antibiotics contained in environmental pollution treatment by-products such as wastewater, wastewater sludge, pharmaceutical wastewater, industrial wastewater, serving, livestock manure, food waste, etc. Can be. Low antibiotic concentrations and scale-up of the radiation dose increase the energy generated by vacuum ultraviolet radiation, enabling antibiotic degradation within 5 minutes.
본 발명에 따른 항생제 분해방법에 있어서, 상기 진공자외선은 수은로부터 발생되는 것을 사용할 수 있다.In the antibiotic decomposition method according to the present invention, the vacuum ultraviolet ray may be generated from mercury.
본 발명에 따른 항생제 분해방법에 있어서, 분해되는 항생제는 가축에 가장 많이 쓰이는 테트라사이클린 계열, 사람 및 가축에 많이 쓰이는 설파제 계열, 세팔로스포린 계열, 클로람페니콜 계열, 마크로라이드 계열 또는 아미노글라이코사이드 계열 등을 포함하며, 구체적으로는 클로로테트라사이클린, 설파메톡사졸, 트리메소프림, 린코마이신 등을 들 수 있다. 이때 항생제의 농도는 100 ppm 이하인 것이 바람직하다.In the antibiotic decomposition method according to the present invention, the antibiotic to be degraded is tetracycline series most used in livestock, sulfase series, cephalosporin series, chloramphenicol series, macrolide series or aminoglycoside series, etc. And chlorotetracycline, sulfamethoxazole, trimesoprim, lincomycin and the like. At this time, the concentration of the antibiotic is preferably 100 ppm or less.
상기 진공자외선을 이용한 방법은 종래 방사선 이용에 필요한 차폐의 번거로움이 없고, 설치가 용이하며 설치 비용도 경제적이고 항생제 분해율도 우수하므로(표 1~3, 도 1~2 참조), 방사선을 대신하여 하폐수 슬러지, 인분, 가축분뇨, 음식물 쓰레기 등의 환경오염 물질 처리 부산물 내에 포함된 항생제를 효과적으로 분해시켜 생물학적 부숙을 극대화시킬 수 있다.Since the method using the vacuum ultraviolet ray does not have the shielding hassle required for conventional radiation use, is easy to install, the installation cost is economical, and the antibiotic decomposition rate is excellent (see Tables 1 to 3 and 1 to 2 ). The biodegradation can be maximized by effectively breaking down antibiotics contained in by-products of environmental pollutants such as sewage sludge, serving, livestock manure and food waste.
또한, 본 발명은 하폐수, 하폐수 슬러지, 제약 폐수, 산업 폐수, 인분, 가축분뇨, 음식물 쓰레기 등으로 이루어지는 환경오염물질 처리 부산물을 상기 진공방사선을 이용한 항생제의 분해방법에 의해 처리하고, 생물학적 처리에 의하여 퇴비화 및 사료화하는 방법을 제공한다.In addition, the present invention is to treat by-products of environmental pollutant treatment consisting of wastewater, wastewater sludge, pharmaceutical wastewater, industrial wastewater, serving, livestock manure, food waste, etc. by the decomposition method of antibiotics using the vacuum radiation, and by biological treatment Provide methods for composting and forageing.
나아가, 본 발명은 하폐수, 하폐수 슬러지, 제약 폐수, 산업 폐수, 인분, 가축분뇨, 음식물 쓰레기 등으로 이루어지는 환경오염물질 처리 부산물을 상기 진공자외선을 이용한 항생제의 분해방법에 의해 처리하고, 생물학적 처리함으로써 제조된 퇴비 또는 사료를 제공한다.Furthermore, the present invention is produced by treating the environmental pollutant by-products consisting of wastewater, wastewater sludge, pharmaceutical wastewater, industrial wastewater, serving, livestock manure, food waste, etc. by the decomposition method of antibiotics using the vacuum ultraviolet ray, and by biological treatment Feed compost or feed.
이하, 본 발명을 실시예에 의해 더욱 상세히 설명한다. 단, 하기의 실시예는 본 발명의 내용을 예시하는 것일 뿐, 본 발명의 내용의 하기의 실시예에 의해 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail by way of examples. However, the following examples are merely illustrative of the contents of the present invention and are not limited by the following examples of the contents of the present invention.
<< 실시예Example 1> 진공자외선을 이용한 항생제 분해 1> Degradation of antibiotics using vacuum ultraviolet
본 발명에 따른 진공자외선을 이용한 항생제 분해효과를 알아보기 위하여 다음과 같은 실험을 수행하였다.In order to determine the antibiotic degradation effect using vacuum ultraviolet rays according to the present invention was carried out the following experiment.
인간과 가축에 많이 투여되는 항생제인 클로로테트라사이클린(chlorotetracycline), 설파메톡사졸(sulfamethoxazole) 또는 트리메소프림(trimethoprim)을 30 mg/L 농도의 수용액으로 제조한 후 상기 수용액에 진공자외선(파장: 185 nm + 254 nm)을 5분, 10분, 15분, 20분, 30분, 50분, 70분, 90분 및 120분 동안 조사하여 항생제 분해율 변화를 수용액 중 항생제 농도(mg/L)의 변화량으로 측정하고, 그 결과를 표 1에 나타내었다.Chlorotetracycline, sulfamethoxazole, or trimethoprim, which are antibiotics that are frequently administered to humans and livestock, are prepared in an aqueous solution of 30 mg / L concentration and then vacuum ultraviolet (wavelength: 185) is applied to the aqueous solution. nm + 254 nm) for 5 minutes, 10 minutes, 15 minutes, 20 minutes, 30 minutes, 50 minutes, 70 minutes, 90 minutes and 120 minutes to determine the change in the rate of antibiotic degradation in the amount of antibiotic concentration (mg / L) in the aqueous solution. Was measured, and the results are shown in Table 1.
(분)time
(minute)
C0: 조사전 농도C: concentration after irradiation
C 0 : concentration before irradiation
표 1에 나타낸 바와 같이, 클로로테트라사이클린의 경우 5분 동안 진공자외선을 조사하였을 경우 50% 이상이 제거되고, 설파메톡사졸은 90% 이상이 제거되며, 70분 후에는 두 물질 모두 완전하게 분해되는 것을 알 수 있다. 또한 트리메소프림은 70분 후에 50% 이상 분해됨을 알 수 있다.As shown in Table 1, when chlorotetracycline is irradiated with vacuum ultraviolet rays for 5 minutes, at least 50% is removed, and sulfamethoxazole is removed at 90%, and after 70 minutes, both substances are completely decomposed. It can be seen that. It can also be seen that trimethoprim decomposes more than 50% after 70 minutes.
따라서, 본 발명에 따라 진공자외선을 조사함으로써 하폐수 내의 항생제를 유의하게 분해시킬 수 있다.Therefore, according to the present invention, by irradiating vacuum ultraviolet rays, antibiotics in the wastewater can be significantly decomposed.
<< 실시예Example 2> 자외선 종류에 따른 항생제 분해효율 2> Degradation efficiency of antibiotics according to ultraviolet rays
자외선 종류에 따른 항생제 분해효율을 알아보기 위하여 다음과 같은 실험을 수행하였다.The following experiment was conducted to determine the antibiotic degradation efficiency according to the type of UV light.
항생제인 린코마이신(lincomycin) 또는 테트라사이클린(tetracycline)을 약 30 mg/L 농도의 수용액으로 제조한 후 상기 수용액에 진공자외선(파장: 185 nm + 254 nm) 또는 살균자외선(UV-C)(파장: 254 nm)을 1~60분 동안 조사하여 항생제 분해율 변화를 수용액 중 항생제 농도(mg/L)의 변화량으로 측정하고, 그 결과를 표 2~3 및 도 1~2에 나타내었다.After preparing antibiotics lincomycin or tetracycline in an aqueous solution of about 30 mg / L concentration, the aqueous solution was vacuum ultraviolet (wavelength: 185 nm + 254 nm) or sterile ultraviolet (UV-C) (wavelength). : 254 nm) was irradiated for 1 to 60 minutes, and the change in the rate of antibiotic degradation was measured by the amount of change in the concentration of antibiotics (mg / L) in the aqueous solution, and the results are shown in Tables 2-3 and FIGS .
상기 표 2 및 도 1은 진공자외선을 조사하였을 때의 항생제의 분해율 변화를 나타내며, 표 3 및 도 2는 살균자외선을 조사하였을 때의 항생제의 분해율 변화를 나타낸다.Table 2 and Figure 1 shows the change in the decomposition rate of antibiotics when irradiated with vacuum ultraviolet rays, Table 3 and Figure 2 shows the change in the decomposition rate of antibiotics when irradiated with ultraviolet rays.
(분)time
(minute)
C0: 조사전 농도C: concentration after irradiation
C 0 : concentration before irradiation
(분)time
(minute)
C0: 조사전 농도C: concentration after irradiation
C 0 : concentration before irradiation
표 2~3 및 도 1~2에 나타낸 바와 같이, 진공자외선을 조사하였을 때에는 항생제가 분해되어 항생제의 농도가 유의적으로 감소하였으나, 살균자외선을 조사하였을 때에는 항생제의 분해 효과가 거의 나타나지 않았다. As shown in Tables 2 to 3 and FIGS. 1 and 2 , when the ultraviolet rays were irradiated, the antibiotics were decomposed and the concentration of the antibiotics was significantly decreased. However, when the germicidal ultraviolet rays were irradiated, the decomposition effect of the antibiotics was hardly observed.
따라서 본 발명에 따른 항생제 분해방법은 진공자외선을 조사함으로써 하폐수 내의 항생제를 유의하게 분해시킬 수 있다.Therefore, the antibiotic decomposition method according to the present invention can significantly decompose antibiotics in the wastewater by irradiating vacuum ultraviolet rays.
도 1은 본 발명의 일실시예에 따른 진공자외선(VUV)을 이용한 항생제 분해효과를 나타내는 그래프이다. 1 is a graph showing the decomposition of antibiotics using vacuum ultraviolet (VUV) according to an embodiment of the present invention.
도 2는 본 발명의 일실시예에 따른 살균자외선(UV-C)을 이용한 항생제 분해효과를 나타내는 그래프이다. Figure 2 is a graph showing the antimicrobial decomposition effect using ultraviolet light (UV-C) according to an embodiment of the present invention.
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| KR20000063389A (en) * | 2000-07-05 | 2000-11-06 | 김용성 | The process of compost and forage from high concentration organic waste water |
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