CN103146761B - Processing method for cephalosporin dreg - Google Patents
Processing method for cephalosporin dreg Download PDFInfo
- Publication number
- CN103146761B CN103146761B CN201310095797.3A CN201310095797A CN103146761B CN 103146761 B CN103146761 B CN 103146761B CN 201310095797 A CN201310095797 A CN 201310095797A CN 103146761 B CN103146761 B CN 103146761B
- Authority
- CN
- China
- Prior art keywords
- sediment
- anaerobic
- slag
- treatment
- cynnematin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
- Y02W10/00—Technologies for wastewater treatment
- Y02W10/20—Sludge processing
Landscapes
- Treatment Of Sludge (AREA)
- Fertilizers (AREA)
Abstract
The invention discloses a processing method for cephalosporin dreg. The processing method comprises the following process steps of: (A) thermal alkaline hydrolysis and separation treatment: uniformly mixing cephalosporin dreg, water and alkali, carrying out constant-temperature alkaline hydrolysis reaction, and carrying out solid-liquid separation at a certain temperature after the constant-temperature alkaline hydrolysis reaction, so as to obtain sediments to be standby; and (B) anaerobic digestion treatment: inoculating anaerobic activated sludge into an anaerobic fermentation tank, mixing the sediments obtained in the step (A) with excess sludge produced by utilizing wastewater biological treatment, injecting the mixture into the fermentation tank, carrying out constant-temperature stirring, and carrying out biogas residue discharging and feeding during fermentation. According to the processing method for the cephalosporin dreg, drug residues in the cephalosporin dreg can be completely removed, the problem that the anaerobic fermentation of single cephalosporin dreg cannot be effectively sustained is solved, and the reduction and innocent treatment to the cephalosporin dreg are realized; and biogas residues produced during the processing process can be used for preparing raw materials of organic fertilizers, the produced sewage gas can be used as clean fuels, and safe and effective disposition and resource utilization to the cephalosporin dreg are realized.
Description
Technical field
The present invention relates to a kind for the treatment of technology of antibiotic bacterium dregs, relate in particular to a kind for the treatment of process of cynnematin bacterium slag.
Background technology
Cynnematin is a class wide spectrum semisynthetic antibiotics, and first cynnematin came out in the sixties in 20th century, and the kind of going on the market has at present reached more than 60 plants, and its output accounts for the more than 60% of microbiotic output in the world.The basic structure of cynnematin is 7-amino-cephalosporanic acid (7-ACA), has beta-lactam feature, and its precursor is cephalosporin.β-lactam antibitics is that clinical use is maximum, most widely used, kind is the most complete, curative effect is best and evaluate a highest class microbiotic, in anti-infective medicine, occupies critical role.In production cynnematin process, when fermentation produces cephalosporin, can produce a large amount of solid waste and be bacterium slag, its water ratio is high, complicated component, not only contain the nutritive substances such as a large amount of tropina (accounting for the more than 40% of dry weight), abundant VITAMIN, somatomedin and substratum residue, and the various meta-bolitess that contain microorganism, comprise micro-cephalosporin.Mycelium in cynnematin bacterium slag is difficult for destroyed, cephalosporin is also comparatively stable, antimicrobial spectrum is also wider, if do not deal carefully with loss entered environment, likely suppress certain micro-organisms kind in environment and normal growth, the procreation of realm, the eubiosis that welding is intrinsic, produces potential harm to ecotope, when serious, may enter food chain, and then harm humans health.
For a long time, people are actively seeking a kind of economic, cynnematin bacterium slag treatment process efficiently and thoroughly always.At present, few about cynnematin bacterium slag method of disposal report both at home and abroad, mainly contain following several: 1) agricultural and livestock industry utilization: owing to containing a large amount of polysaccharide, protein and multiple amino acids and trace element in cynnematin bacterium slag, therefore from five sixties of last century, be widely used as feed, additive or fertilizer.But on August 1st, 2008, China clearly classifies antibiotic bacterium dregs as " Hazardous wastes ", forbid that antibiotic bacterium dregs is directly as feed, fertilizer; 2) burn: cynnematin bacterium slag incineration disposal can promptly make bacterium slag turn to dust and ashes and reach minimizing, innoxious object, it is the treatment process that meets laws and regulations requirement at present most, but because cynnematin bacterium slag has the features such as output is large, water ratio is high, calorific value is low, bacterium slag is dry need to consume a large amount of energy; And cynnematin bacterium slag also contains the more element such as sulphur and nitrogen, increase the burden that removes sulfurous gas and oxynitrides in incineration tail gas; Therefore, burn cost very high, and existing danger waste burning facility ability can not satisfy the demands far away, cynnematin bacterium slag incineration disposal is difficult to carry out; 3) landfill: landfill is the technology of a comparative maturity, this method of disposal simply, easily go, but because cynnematin bacterium slag water ratio is high, landfill need to shift to an earlier date predrainage, and the landfill of bacterium slag exist the large and transudate of addressing difficulty, shipment distance may polluted underground water etc. problem.In addition,, because the mycelium in cynnematin bacterium slag is difficult for destroyedly, cynnematin is also comparatively stable, and its antimicrobial spectrum is wide compared with penicillin, makes subduing of cynnematin seem more important and difficult.The antibiotic bacterium dregs innocent treatment technologies such as the penicillin of having developed at present are also not exclusively applicable to the harmless treatment of cynnematin bacterium slag.
CN201110409090 discloses a kind of method of disposing residues produced by fermentation of cephalosporin C through alkaline hydrolysis process.Concrete steps comprise: 1. cephalosporin is produced the pre-treatment of residue: cephalosporin is produced to residue and alkaline solution joins in mixing tank, make its pH of mixed between 9-11, cover sealing cover, electric stirring 20-30min, is pumped into the mixed solution stirring in hydrolytic reaction pot; 2. hydrolysis: hydrolytic process is used hydrolytic reaction pot, heat reactor with thermal oil and is incubated, and is 0.4-0.7Mpa in operating pressure, and hydrolysis temperature is that under the condition of 150 ℃-220 ℃, hydrolysis time is 1-3h, in hydrolytic process, is incubated and starts stirring simultaneously; 3. filter: after hydrolysis, the mixed solution after hydrolysis is carried out to solid-liquid separation with solid-liquid separating equipment, collect filtrate and filter residue.The drug residue of this invention in can basically eliminate cynnematin bacterium slag, has realized the harmless treatment of cynnematin bacterium slag, but unrealized minimizing and resource utilization to it; And the method need to provide elevated pressures and temperature, there is certain security risk in operating process, and energy consumption is large, cost is high, has limited to a certain extent its application.
Summary of the invention
The technical issues that need to address of the present invention are to provide a kind of method that can process cynnematin bacterium slag economic, efficiently, up hill and dale.
For solving the problems of the technologies described above, the technical solution used in the present invention is:
A treatment process for cynnematin bacterium slag, comprises following processing step:
A, thermokalite solution and separating treatment: cynnematin bacterium slag, water and alkali are evenly mixed, carry out the reaction of constant temperature alkaline hydrolysis, leave standstill at a certain temperature after completion of the reaction, solid-liquid separation processing, form supernatant liquor and sediment, supernatant liquor is introduced to conventional Waste Water Treatment and process, sediment is for subsequent use;
B, Anaerobic Digestion: first in anaerobic fermentation tank, inoculate anaerobic activated sludge, then the excess sludge sediment of steps A gained being produced with biological wastewater treatment mixes, obtain sediment mud mixture, and described sediment mud mixture is injected to anaerobic fermentation tank, finally under agitation carry out ferment at constant temperature, in fermenting process, arrange natural pond slag and feed operation.
Further improvement of the present invention is: the concrete reaction conditions of described steps A is that 1 part～4 parts, 300 parts～800 parts, 100 parts～200 parts of cynnematin bacterium slags, water, the sodium hydroxide counted is by weight joined in reactor; The temperature of alkaline hydrolysis reaction is 40 ℃～55 ℃, and the time of alkaline hydrolysis reaction is 3.0h～5.0h; After completion of the reaction reaction product is left standstill at 35 ℃～40 ℃, carry out solid-liquid separation processing, time of repose is 10h～14h; The solid content of gained sediment is 5%～8%.
Further improvement of the present invention is: in described step B, in anaerobic fermentation tank, the injection rate of anaerobic activated sludge is tank volume 50%～80%; In described sediment mud mixture, the sediment of steps A gained and the volume ratio of the excess sludge that wastewater treatment produces are 1:1～4:1; In anaerobic fermentation tank, the add-on of sediment mud mixture is 2%～6% of anaerobically fermenting tank volume; The intensity of described stirring is 80rpm～150rpm, and anaerobically fermenting temperature is 50 ℃～60 ℃; Described row natural pond slag and feed operation are intermittent type.
Further improvement of the present invention is: the timed interval of described intermittent type row's natural pond slag and feed operation is 6h～24h, and row natural pond slag total amount and the charging total amount of every 24h are 2%～6% of anaerobically fermenting tank volume.
Further improvement of the present invention is: by the biogas producing in described step B in order to produce steam, the heat source with this steam as thermokalite solution and anaerobic digestion.
Further improvement of the present invention is: the natural pond slag that step B is produced is collected also as the raw material of preparing fertilizer.
Owing to having adopted technique scheme, the obtained technical progress of the present invention is:
The treatment process of cynnematin bacterium slag of the present invention can realize the efficient, economic of cynnematin bacterium slag and thoroughly process, and has thoroughly solved cephalo mycelium and has been difficult to fragmentation, cephalosporin difficult degradation and the anaerobic digestion of single cynnematin bacterium slag and is difficult to the high-efficiency continuous problem such as carry out.The present invention has realized minimizing, the harmless treatment to cynnematin bacterium slag by thermokalite solution and separating treatment in conjunction with two processing steps of Anaerobic Digestion, easy and simple to handle, treatment effect is good, there is significant environmental and social benefits and certain economic benefit, thoroughly eliminated drug residue in cynnematin bacterium slag and the Pollution risk to environment thereof.The biogas that anaerobic digestion produces can be used as energy utilization, and natural pond slag can be used as raw material and prepares fertilizer, has realized the recycling of cynnematin bacterium slag, for safe disposal and reasonable utilization of antibiotic bacterium dregs provide effective way.
Thermokalite solution in the present invention and separating treatment technique, first by adding alkali number, temperature of reaction, isoparametric control of reaction times, microbiotic residual in cynnematin bacterium slag and triumphant nitrogen are tentatively subdued, making to enter the residual and triumphant nitrogen of cephalosporin in the cynnematin bacterium slag of anaerobic digestion significantly reduces, basically eliminate the residual impact on Anaerobic Digestion of cynnematin, effectively alleviate the impact of ammonia nitrogen on Anaerobic Digestion, created favorable conditions for anaerobic digestion is efficient, stable.After processing, thermokalite solution passes through separating treatment, at 35 ℃～40 ℃, leave standstill 10h～14h by thermokalite hydrolysis products, be separated into supernatant liquor and sediment, the solid content of sediment is 5%～8%, has significantly cut down the amount of solid of the cynnematin bacterium slag that enters Anaerobic Digestion.And due to after thermokalite solution is processed, the drug residue in the supernatant liquor of separating treatment gained is little, can realize the harmless treatment to it through conventional Waste Water Treatment.Therefore, only need separating treatment gained sediment to carry out anaerobic digestion, significantly cut down the amount of solid of the cynnematin bacterium slag that enters Anaerobic Digestion, reduction is greater than 47% after testing, thereby has reduced the processing cost of cynnematin bacterium slag.
Anaerobic digestion process in the present invention, first excess sludge cynnematin bacterium slag and biological wastewater treatment being produced mixes, further improve the nutritional condition of anaerobically fermenting matrix, reduce the restraining effect of ammonia nitrogen to anaerobically fermenting, and contribute to the maintenance of anaerobic fermentation system biomass, for favourable condition has been created in efficient, the lasting anaerobic digestion of cynnematin bacterium slag.Then by the control of the factor such as solid content and dosing ratio, stirring intensity, leavening temperature, the row natural pond quantity of slag and inlet amount to sediment mud mixture, realize stable, the efficiently operation of the anaerobic digestion of cynnematin bacterium slag, eliminate residual microbiotic completely, further subdued the solid masses of cynnematin bacterium slag.
In the present invention, the anaerobic digestion of cynnematin bacterium slag can steady running under high loading, high solid content condition, in the natural pond slag producing through anaerobic digestion, cephalosporin is residual extremely low, the residual < 0.05mg/kg of cephalosporin, and the residual of this dosage can not work the mischief to plant and human body, and owing to containing a large amount of polysaccharide, protein and multiple amino acids and trace element in the slag of natural pond, not containing heavy metal and toxic and harmful substance.Therefore, gained natural pond slag can be used as produces the raw material of fertilizer, cynnematin bacterium slag resource is obtained rationally, fully, effectively utilize, and reduce environmental pollution.
In anaerobic digestion process of the present invention, the product biogas amount of unit sediment mud mixture is greater than 420m
3/ ton (butt), the biogas producing can be in order to produce steam, and gained steam can be used as the thermal source of the reaction of thermokalite solution and anaerobically fermenting, has realized the recycle of resource.
Embodiment
Below in conjunction with embodiment, the present invention is explained in further detail, umber related in following embodiment is parts by weight.
Embodiment 1
A, thermokalite solution and separating treatment: 1 part, 200 parts of cynnematin bacterium slags, 300 parts, water and sodium hydroxide is joined in reactor, stir material is evenly mixed; Adopt steam heating mode to make reactor temperature rise to 40 ℃, isothermal reaction 3.0h; After completion of the reaction material in reactor is carried out to separating treatment, at 35 ℃, leave standstill 14h by reaction product, make it form supernatant liquor and sediment; Finally supernatant liquor is introduced to conventional Waste Water Treatment and processed, stay sediment for subsequent use, the solid content of gained sediment is 8%.
B, Anaerobic Digestion: first the anaerobic activated sludge for anaerobically fermenting tank volume 50% is seeded in anaerobic fermentation tank; The excess sludge simultaneously sediment of steps A gained being produced with the biological wastewater treatment by volume ratio of 3:1 evenly mixes, and obtains a kind of sediment mud mixture; Then the above-mentioned sediment mud mixture for anaerobically fermenting tank volume 2% is injected to anaerobic fermentation tank by the slag inlet on anaerobic fermentation tank, open whipping appts and heating unit on anaerobic fermentation tank simultaneously, stirring intensity is 150rpm, and controlled fermentation temperature is 50 ℃; In fermenting process, once arrange natural pond slag operation every 24h, every 24h, the natural pond slag of gained after Anaerobic Digestion that is anaerobically fermenting tank volume 2% is discharged from the slag-drip opening of anaerobic fermentation tank; After deslagging, carry out immediately one time feed operation, be about to inject anaerobic fermentation tank for the sediment mud mixture of anaerobically fermenting tank volume 2% from slag inlet.The biogas producing in anaerobic digestion process is discharged from the methane outlet of anaerobic fermentation tank, and enters methane boiler burning and make to produce steam in boiler, and gained steam is in order to heat alkaline hydrolysis reactor and anaerobic fermentation tank.
Get gained after cynnematin bacterium slag, thermokalite solution and the separating treatment in embodiment 1 sediment and supernatant liquor, after Anaerobic Digestion, the natural pond slag of gained detects analysis, result is as shown in table 1 below:
Table 1
| Material | Cephalosporin is residual | Triumphant nitrogen is residual | Amount of solid decrement |
| Cynnematin bacterium slag raw material | 2235mg/kg | 7843mg/L | ? |
| Thermokalite solution and separating treatment gained sediment | 0.45mg/kg | 4267?mg/L | 47.5% |
| Thermokalite solution and separating treatment gained supernatant liquor | 0.21mg/?kg | 1187?mg/L | ? |
| Anaerobic Digestion gained natural pond slag | ＜0.05mg/?kg | 3914?mg/L | 63.3% |
From upper table 1, the cynnematin bacterium slag raw material in embodiment 1 through thermokalite solution process after, cynnematin residue removal rate > 99.98%, solid decrement 47.5%, triumphant nitrogen subdues 45.4%; Cynnematin bacterium slag raw material in embodiment 1 through thermokalite solution process and Anaerobic Digestion after, cynnematin residue removal rate > 99.99%, solid decrement 63.3%.
Embodiment 2
A, thermokalite solution and separating treatment: 4 parts of 200 parts of cynnematin bacterium slags, 800 parts, water, sodium hydroxide are joined in reactor and joined in reactor, stir material is evenly mixed; Adopt steam heating mode to make reactor temperature rise to 55 ℃, isothermal reaction 5.0h; After completion of the reaction material in reactor is carried out to separating treatment, at 40 ℃ of standing 10h, make it form supernatant liquor and sediment by reaction product, finally supernatant liquor is introduced to conventional Waste Water Treatment and processed, stay sediment for subsequent use, the solid content of gained sediment is 5%.
B, Anaerobic Digestion: first the anaerobic activated sludge for anaerobically fermenting tank volume 80% is seeded in anaerobic fermentation tank; Then the sediment of steps A gained is produced with biological wastewater treatment excess sludge by volume 4:1 evenly mix, obtain a kind of sediment mud mixture; Then the above-mentioned sediment mud mixture for anaerobically fermenting tank volume 6% is divided and is injected in anaerobic fermentation tank by the slag inlet on anaerobic fermentation tank for four times in 24h, open whipping appts and heating unit simultaneously, stirring intensity is 100rpm, and controlled fermentation temperature is 55 ℃.During the fermentation, once arrange natural pond slag operation every 6h, each bed drain purge is 1.5% of anaerobically fermenting tank volume, divides four slag-drip openings from anaerobic fermentation tank to discharge at 6% the natural pond slag of gained after Anaerobic Digestion that in 24h by total amount is anaerobically fermenting tank volume; After each deslagging, carry out immediately feed operation one time, each inlet amount is 1.5% of anaerobically fermenting tank volume, in 24h, is that 6% sediment mud mixture of anaerobically fermenting tank volume divides and injects anaerobic fermentation tank from slag inlet four times by total amount.The biogas producing in Anaerobic Digestion process is discharged from the methane outlet of anaerobic fermentation tank, and enters methane boiler burning and make to produce steam in boiler, and gained steam is in order to heat hot alkaline hydrolysis reactor and anaerobic fermentation tank.
Get cynnematin bacterium slag in embodiment 2, through thermokalite solution and separating obtained sediment and supernatant liquor, after anaerobic digestion, the natural pond slag of gained detects analysis, result is as shown in table 2 below:
Table 2
| Material | Cephalosporin is residual | Triumphant nitrogen is residual | Amount of solid decrement |
| Cynnematin bacterium slag raw material | 2185mg/kg | 7486?mg/L | ? |
| Thermokalite solution and separating treatment gained sediment | ＜0.1mg/kg | 3556mg/L | 56% |
| Thermokalite solution and separating treatment gained supernatant liquor | ＜0.1mg/kg | 1020mg/L | ? |
| Anaerobic Digestion gained natural pond slag | ＜0.05mg/kg | 3167mg/L | 71.4% |
From upper table 2, the cynnematin bacterium slag raw material in embodiment 2 through thermokalite solution process after, cynnematin residue removal rate > 99.99%, solid decrement 56%, triumphant nitrogen subdues 54.5%; Cynnematin bacterium slag raw material in embodiment 2 through thermokalite solution process and Anaerobic Digestion after, cynnematin residue removal rate > 99.99%, solid decrement 71.4%.
Embodiment 3
A, thermokalite solution and separating treatment: 3 parts of 150 parts of cynnematin bacterium slags, 600 parts, water, sodium hydroxide are joined in reactor, stir material is evenly mixed; Adopt steam heating mode to make reactor temperature rise to 50 ℃, isothermal reaction 4.0h; After completion of the reaction material in reactor is carried out to separating treatment, at 37 ℃, leave standstill 13h by reaction product, make it form supernatant liquor and sediment; Finally supernatant liquor is introduced to conventional Waste Water Treatment and processed, stay sediment for subsequent use, the solid content of gained sediment is 6%.
B, Anaerobic Digestion: first the anaerobic activated sludge for anaerobically fermenting tank volume 70% is seeded in anaerobic fermentation tank; Then the excess sludge sediment of steps A gained being produced with biological wastewater treatment by volume 1:1 evenly mixes, and obtains a kind of sediment mud mixture; Then the above-mentioned sediment mud mixture for anaerobically fermenting tank volume 4% is injected in anaerobic fermentation tank by the slag inlet on anaerobic fermentation tank at twice in 24h, open whipping appts and heating unit simultaneously, stirring intensity is 120rpm, and controlled fermentation temperature is 60 ℃.During the fermentation, once arrange natural pond slag operation every 12h, each bed drain purge is 2% of anaerobically fermenting tank volume, discharges from the slag-drip opening of anaerobic fermentation tank at twice at 4% the natural pond slag of gained after Anaerobic Digestion that in 24h by total amount is anaerobically fermenting tank volume; After each deslagging, carry out immediately feed operation one time, each inlet amount is 2% of anaerobically fermenting tank volume, in 24h, is that 4% sediment mud mixture of anaerobically fermenting tank volume injects anaerobic fermentation tank from slag inlet at twice by total amount.The biogas producing in Anaerobic Digestion process is discharged from the methane outlet of anaerobic fermentation tank, and enters methane boiler burning and make to produce steam in boiler, and gained steam is in order to heat hot alkaline hydrolysis reactor and anaerobic fermentation tank.
Get cynnematin bacterium slag in embodiment 3, through sediment and the supernatant liquor of thermokalite solution and separating treatment gained, after Anaerobic Digestion, the natural pond slag of gained detects analysis, result is as shown in table 3 below:
Table 3
| Material | Cephalosporin is residual | Triumphant nitrogen is residual | Amount of solid decrement |
| Cynnematin bacterium slag raw material | 2290mg/kg | 7801?mg/L | ? |
| Thermokalite solution and separating treatment gained sediment | 0.31mg/kg | 3838mg/L | 52.1% |
| Thermokalite solution and separating treatment gained supernatant liquor | 0.1mg/kg | 991mg/L | ? |
| Anaerobic Digestion gained natural pond slag | ＜0.05mg/kg | 3729mg/L | 66.3% |
From upper table 3, the cynnematin bacterium slag raw material in embodiment 3 through thermokalite solution process after, cynnematin residue removal rate > 99.99%, solid decrement 52.1%, triumphant nitrogen subdues 50.8%; Cynnematin bacterium slag raw material in embodiment 3 after thermokalite solution and Anaerobic Digestion, cynnematin residue removal rate > 99.99%, solid decrement 66.3%.
Embodiment 4
A, thermokalite solution and separating treatment: 2 parts of 100 parts of cynnematin bacterium slags, 500 parts, water, sodium hydroxide are joined in reactor, stir material is evenly mixed; Adopt steam heating mode to make reactor temperature rise to 45 ℃, isothermal reaction 3.5h; After completion of the reaction material in reactor is carried out to separating treatment, at 40 ℃, leave standstill 12h by reaction product, make it form supernatant liquor and sediment; Finally supernatant liquor is introduced to conventional Waste Water Treatment and processed, stay sediment for subsequent use, the solid content of gained sediment is 7%.
B, Anaerobic Digestion: first the anaerobic activated sludge note for anaerobically fermenting tank volume 60% is seeded in anaerobic fermentation tank; The wastewater sludge simultaneously sediment of steps A gained being produced with wastewater treatment by volume 2:1 evenly mixes, and obtains a kind of sediment mud mixture; Then the above-mentioned sediment mud mixture for anaerobically fermenting tank volume 3% is divided and is injected in anaerobic fermentation tank by the slag inlet on anaerobic fermentation tank for three times in 24h, open whipping appts and heating unit simultaneously, stirring intensity is 80rpm, and controlled fermentation temperature is 60 ℃.In fermenting process, once arrange natural pond slag operation every 8h, each bed drain purge is 1% of anaerobically fermenting tank volume, divides three slag-drip openings from anaerobic fermentation tank to discharge at 3% the natural pond slag of gained after Anaerobic Digestion that in 24h by total amount is anaerobically fermenting tank volume; After each deslagging, carry out immediately feed operation one time, each inlet amount is 1% of anaerobically fermenting tank volume, in 24h, is that 3% sediment mud mixture of anaerobically fermenting tank volume divides and injects anaerobic fermentation tank from slag inlet three times by total amount.The biogas producing in Anaerobic Digestion process is discharged from the methane outlet of anaerobic fermentation tank, and enters methane boiler burning and make to produce steam in boiler, and gained steam is in order to heat hot alkaline hydrolysis reactor and anaerobic fermentation tank.
Get cynnematin bacterium slag in embodiment 4, through sediment and the supernatant liquor of thermokalite solution and separating treatment gained, after Anaerobic Digestion, the natural pond slag of gained detects analysis, result is as shown in table 4 below:
Table 4
| Material | Cephalosporin is residual | Triumphant nitrogen is residual | Amount of solid decrement |
| Cynnematin bacterium slag raw material | 2375mg/kg | 8290?mg/L | ? |
| Thermokalite solution and separating treatment gained sediment | 0.25mg/kg | 4137mg/L | 50.5% |
| Thermokalite solution and separating treatment gained supernatant liquor | 0.13mg/kg | 1510mg/L | ? |
| Anaerobic Digestion gained natural pond slag | ＜0.05mg/?kg | 4079mg/L | 68.4% |
From upper table 4, the cynnematin bacterium slag raw material in embodiment 4 through thermokalite solution process after, cynnematin residue removal rate > 99.99%, solid decrement 50.5%, triumphant nitrogen subdues 50.1%; Cynnematin bacterium slag in embodiment 4 after thermokalite solution and Anaerobic Digestion, cynnematin residue removal rate > 99.99%, solid decrement 68.4%.
The natural pond slag that the various embodiments described above are produced carries out Hazardous wastes discriminating, and the natural pond slag after accreditation can be for the preparation of the raw material of agriculture fertilizer.
Claims (1)
1. a treatment process for cynnematin bacterium slag, is characterized in that comprising following processing step:
A, thermokalite solution and separating treatment: cynnematin bacterium slag, water and alkali are evenly mixed, carry out the reaction of constant temperature alkaline hydrolysis, leave standstill at a certain temperature after completion of the reaction, solid-liquid separation processing, form supernatant liquor and sediment, supernatant liquor is introduced to conventional Waste Water Treatment and process, sediment is for subsequent use;
B, Anaerobic Digestion: first in anaerobic fermentation tank, inoculate anaerobic activated sludge, then the excess sludge sediment of steps A gained being produced with biological wastewater treatment mixes, obtain sediment mud mixture, and described sediment mud mixture is injected to anaerobic fermentation tank, finally under agitation carry out ferment at constant temperature, in fermenting process, arrange natural pond slag and feed operation;
The concrete reaction conditions of described steps A is that 1 part ~ 4 parts, 300 parts ~ 800 parts, 100 parts ~ 200 parts of cynnematin bacterium slags, water, the sodium hydroxide counted is by weight joined in reactor; The temperature of alkaline hydrolysis reaction is 40 ℃ ~ 55 ℃, and the time of alkaline hydrolysis reaction is 3.0h ~ 5.0h; After completion of the reaction reaction product is left standstill at 35 ℃ ~ 40 ℃, carry out solid-liquid separation processing, time of repose is 10h ~ 14h; The solid content of gained sediment is 5% ~ 8%;
In described step B, in anaerobic fermentation tank, the injection rate of anaerobic activated sludge is tank volume 50% ~ 80%; In described sediment mud mixture, the sediment of steps A gained and the volume ratio of the excess sludge that wastewater treatment produces are 1:1 ~ 4:1; In anaerobic fermentation tank, the add-on of sediment mud mixture is 2% ~ 6% of anaerobically fermenting tank volume; The intensity of described stirring is 80rpm ~ 150rpm, and anaerobically fermenting temperature is 50 ℃ ~ 60 ℃; Described row natural pond slag and feed operation are intermittent type;
The timed interval of described intermittent type row's natural pond slag and feed operation is 6h～24h, and row natural pond slag total amount and the charging total amount of every 24h are 2%～6% of anaerobically fermenting tank volume.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310095797.3A CN103146761B (en) | 2013-03-22 | 2013-03-22 | Processing method for cephalosporin dreg |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310095797.3A CN103146761B (en) | 2013-03-22 | 2013-03-22 | Processing method for cephalosporin dreg |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103146761A CN103146761A (en) | 2013-06-12 |
| CN103146761B true CN103146761B (en) | 2014-06-04 |
Family
ID=48545079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310095797.3A Active CN103146761B (en) | 2013-03-22 | 2013-03-22 | Processing method for cephalosporin dreg |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103146761B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103865791B (en) * | 2014-03-07 | 2016-01-20 | 河北科技大学 | A kind for the treatment of unit of Streptomycin sulphate bacterium slag and method thereof |
| CN103820315B (en) * | 2014-03-07 | 2015-09-02 | 河北科技大学 | A kind of device and method of cephalosporin dreg harmless treatment |
| CN103865790B (en) * | 2014-03-07 | 2016-02-10 | 河北科技大学 | The device of a kind of terramycin strain slag harmlessness process and technique |
| CN104212840B (en) * | 2014-09-03 | 2017-12-12 | 郑州大学 | A kind of processing method of antibiotic fermentation bacteria residue |
| CN105013797B (en) * | 2015-06-30 | 2017-05-31 | 河北省建筑材料工业设计研究院 | The method of the useless dregs of a decoction in the innoxious cooperative disposal pharmaceutical factory of cement kiln |
| CN106111664B (en) * | 2016-06-23 | 2018-10-12 | 浙江微技环境修复工程有限公司 | A kind of processing unit and its method of sulfuric acid polymyxin fermentation bacteria residue |
| CN107008734B (en) * | 2017-05-17 | 2019-11-05 | 成都德菲环境工程有限公司 | A kind of method of harmless resource processing antibiotic bacterium dregs |
| CN107119079B (en) * | 2017-07-03 | 2021-02-09 | 南京农业大学 | Method for mixed wet anaerobic digestion co-treatment of echinocandin bacterial residues and sludge |
| CN110090843A (en) * | 2018-01-29 | 2019-08-06 | 连云港润众制药有限公司 | A kind of processing method of microbial fermentation drug waste bacterial slag |
| CN112624537B (en) * | 2019-09-24 | 2023-05-05 | 中国石油化工股份有限公司 | Method and system for reducing biochemical excess sludge |
| CN113354490B (en) * | 2021-07-21 | 2022-10-04 | 清华大学 | Method for improving aerobic composting effect of cephalosporin fermentation bacteria residues by using electron beam irradiation |
| CN116251823A (en) * | 2023-02-23 | 2023-06-13 | 伊犁川宁生物技术股份有限公司 | Harmless treatment method for cephalosporin residues |
| CN119771896A (en) * | 2025-01-08 | 2025-04-08 | 中山大学 | A method and device for bioresource and harmless treatment of discarded cephradine drugs |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1394262A1 (en) * | 2002-08-30 | 2004-03-03 | Bioferma Murcia, S.A. | An enzymatic process for preparing beta-lactams |
| CN101624605A (en) * | 2008-07-08 | 2010-01-13 | 武汉烁森生态科技有限公司 | Biological method for processing spiramycin bacteria residue |
| CN101323862B (en) * | 2008-07-24 | 2011-01-12 | 南阳普康药业有限公司 | Processing process of albiotic residue |
| KR101105349B1 (en) * | 2008-10-17 | 2012-01-16 | 한국원자력연구원 | Decomposition of antibiotics using vacuum ultraviolet |
| CN101935682B (en) * | 2010-08-20 | 2012-07-18 | 石药集团中诺药业（石家庄）有限公司 | Application method for cephalosporin C bacterium residue |
| CN102488997B (en) * | 2011-12-09 | 2013-09-11 | 天津市裕川环境科技有限公司 | Method for disposing residues produced by fermentation of cephalosporin C through alkaline hydrolysis process |
-
2013
- 2013-03-22 CN CN201310095797.3A patent/CN103146761B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103146761A (en) | 2013-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103146761A (en) | Processing method for cephalosporin dreg | |
| CN103146762B (en) | Treatment method of penicillin mushroom dregs | |
| CN102234170B (en) | Method and device for rapidly reducing moisture content of sludge | |
| CN105855275B (en) | A kind of processing method of sludge and kitchen garbage | |
| CN102992559B (en) | Method for comprehensively utilizing anaerobic digestion and carbonization of municipal sludge | |
| CN105642652B (en) | A kind of recycling processing method of antibiotic bacterium dregs | |
| CN115069739A (en) | Bidirectional reinforced multi-source cooperative full-amount recycling treatment system and technology for kitchen waste | |
| CN102371266B (en) | Resource utilization method of kitchen waste | |
| CN101993181B (en) | Method for dehydration and recycling of continuous dyeing sludge | |
| CN103240264A (en) | Low-emission solid organic waste treatment system realizing methane and active carbon production | |
| CN102212561B (en) | Processing method of straw combined with dry method and wet method | |
| CN107460111A (en) | Organic solid castoff processing system and its method of disposal based on subcritical hydrolysis | |
| CN102336508A (en) | Rapid dehydration and resource treatment method and system for urban domestic sludge | |
| CN103451095A (en) | Method for preparing marsh gas through straw, excrement and kitchen waste | |
| CN104692847A (en) | Method for producing high-macroelement liquid organic special fertilizer | |
| CN104593433A (en) | Method and equipment for treating antibiotic mycelium residues | |
| CN1966166A (en) | Six-segment process for kitchen garbage to regenerate grease, bio-natural gas, medicinal fertilizer, feedstuff | |
| CN206262969U (en) | A kind of kitchen garbage, sludge and green garbage cooperative disposal system | |
| CN103820315A (en) | Device and method for harmless treatment of cynnematin germ dregs | |
| CN103553288A (en) | Method for preparing water treatment biological activity accelerant from winery wastewater treatment sludge | |
| CN104673629A (en) | Anaerobic fermentation system and method for producing biogas by carrying out sludge digestion reaction through anaerobic fermentation system | |
| CN103865790A (en) | Oxytetracycline mushroom residue harmless treatment device and technology | |
| CN202543012U (en) | Fluid sludge treatment device for generating clean combustible gas | |
| CN109503232A (en) | A kind of garbage fermentation system and method for garbage incinerating power plant | |
| CN113149734A (en) | High-reduction low-cost municipal sludge composting treatment method and system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 050015 Changan District East Road, Hebei, Shijiazhuang, No. 388 Applicant after: NORTH CHINA PHARMACEUTICAL GROUP, INSTITUTE OF ENVIRONMENTAL PROTECTION Address before: 050015 Changan District East Road, Hebei, Shijiazhuang, No. 388 Applicant before: North China Pharmaceutical Group, Institute of Environmental Protection |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: NORTH CHINA PHARMACEUTICAL GROUP INSTITUTE OF ENVIRONMENTAL PROTECTION TO: HEBEI HUAYAO ENVIRONMENTAL PROTECTION INSTITUTE CO., LTD. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |