KR100980286B1 - Antimicrobial plastics and antimicrobial oil paint - Google Patents

Abstract

The present invention provides an antimicrobial plastic comprising a synthetic resin, 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one, and 5-chloro-2- (2,4-chlorophenoxy) phenol. to provide. The 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one is included in an amount of 0.01 to 5.0 wt% based on the total weight of the antibacterial plastic, and the 5-chloro-2- (2,4- Chlorophenoxy) phenol is included in an amount of 0.01 to 5.0% by weight based on the total weight of the antibacterial plastic.

The antimicrobial plastics have an excellent antimicrobial activity to gram positive bacteria, gram negative bacteria, and fungi, while containing a smaller amount of antimicrobial agents than before, and the antimicrobial activity is maintained for a long time even in the presence of a large amount of water, and excellent antimicrobial activity against bacterial strains. And less harmful to human body.

Antibacterial product, Antibacterial drainage, Antibacterial air conductor, Antibacterial hose, Antibacterial pipe, Antibacterial waste container, Antibacterial plastic, Oil paint, Antibacterial oil paint

Description

Antibacterial plastic and antibacterial oil paint {ANTIMICROBIAL PLASTICS AND ANTIMICROBIAL OIL PAINT}

The present invention relates to an antimicrobial plastic and an antimicrobial oil paint, and more particularly, to include gram-positive bacteria, gram-negative bacteria, and fungi, all of which contain a smaller amount of antimicrobial agents, and have excellent antimicrobial activity even in an environment where a large amount of water is present. This is maintained for a long time, excellent antimicrobial activity against bacterial strains, and less harmful to human body antibacterial plastic and antibacterial oil paint.

In general, the drain is a place where water is drained or drained, and is provided in various facilities where water is drained, such as a sink, a bathroom, a veranda building, or a factory, to discharge sewage generated after various work to the outside. Used.

The sewage remains various food nutrients and various suspended nutrients used in human sebum, factories, or buildings, and becomes a nutrient source for bacteria and fungi to inhabit the drains. Sludge is formed around the drain hole by metabolites such as bacteria or fungi, and odors are generated, and bacteria and molds harmful to various human bodies are multiplied and propagated to the outside, thereby causing a problem.

In addition, drains are associated with sewers that process various sewage, causing various types of bacteria and fungi to live in the sewers, causing odors in the drains, and flies and mosquitoes that propagate harmful bacteria to humans. There is a problem that causes various pollution.

In order to remove various bacteria and molds, a sterilization method has been used by chemical decomposition of bacteria or molds using a chlorine bleach such as trichloro isocyanuric acid powder or an aqueous solution of sodium hypochlorite. However, chlorine bleach, such as trichloro isocyanurine, has a strong oxidizing power and there is a risk of corroding the sink and the metal around it, and generates toxic chlorine gas. In particular, the reaction with acidic substances such as vinegar significantly increases the generation of chlorine gas, and if inhaled by humans have a harmful effect on the human body.

In addition, a method of sterilization using an oxygen-based bleach such as sodium percarbonate powder or hydrogen peroxide solution has also been used. However, the oxygen-based bleach has a high solubility, so that it dissolves quickly when it comes in contact with water, and thus has a problem in terms of persistence.Therefore, the oxygen-based bleach has a problem in that the oxidizing power is very weak compared to the chlorine-based bleach, so that bacteria or molds causing mucus cannot be sterilized. .

On the other hand, as a method of including the sterilizing material in the drain in the drain production process in order to sterilize bacteria and fungi, a method of adding the sterilizing material to the synthetic resin material injected in liquid form or powder form is mainly used. However, sterilization materials are highly concentrated and usually toxic, so handling is extremely dangerous, and when added in powder form, they are scattered and spread to the outside, which contaminates workers and machines. Therefore, the production is difficult.

In addition, when added in a liquid form does not cause the problem of scattering like powder form, but the liquid itself is toxic, it may cause loss of sight when contacting the eyes of the operator, and rash occurs when contacted with the skin. Accordingly, the work must be carried out while wearing rubber gloves and protective glasses at all times, thereby reducing production efficiency and threatening worker safety.

In addition, various antimicrobial products that have been advertised to prevent infection by bacteria or fungi that proliferate on the surface thereof, as well as the drains, have been antimicrobial only to any one type of bacteria or fungi, There is a problem that the antimicrobial activity disappears in a short time. Accordingly, there is a need for an antimicrobial product that continuously maintains a broad and effective antimicrobial activity against various bacteria and fungi.

On the other hand, there is always a lot of moisture in a damp basement, a wall with cabinets or objects, and the walls of an apartment's veranda. This moisture causes the fungus to multiply and the multiplying fungus spores into the air, causing asthma. In addition, mold destroys wallpaper or painted surfaces, shortening the lifespan of buildings, which is not good for aesthetics.

In the case of buildings made of wood, during the rainy season the wood contains a lot of moisture. Accordingly, even if the wood is preservative treatment, bacteria and fungi fermenting fungi, algae and cellulose, which is a wood component, are multiplied, which shortens the life of the wood building. Therefore, it is necessary to increase the life of the building and keep the exterior of the building clean by suppressing the growth of mold, algae and bacteria.

In addition, in the industrial aspect, sludge generated in manufacturing facilities such as paper mills, leather manufacturing plants, etc. is an important factor for reducing product quality and reducing productivity. Therefore, the demand for improving the quality and increasing the productivity by suppressing the generation of sludge in the manufacturing facility is increasing.

The purpose of the present invention is to include an antimicrobial agent of less than the existing content while having excellent antimicrobial activity to all gram positive bacteria, gram negative bacteria, and fungi, the antimicrobial activity is maintained for a long time even in the presence of a large amount of water, It is to provide an excellent antimicrobial plastics and antimicrobial oil paints less harmful to the human body.

In order to achieve the above object, according to one embodiment of the present invention, a synthetic resin, 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one (4,5-dichloro-2-n- octyl-4-isothiazoline-3-one, DCOIT), and 5-chloro-2- (2,4-chlorophenoxy) phenol (5-chloro-2- (2,4-dichlorophenoxy) phenol, triclosan) To provide antibacterial plastic. The 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one is included in an amount of 0.01 to 5.0 wt% based on the total weight of the antibacterial plastic, and the 5-chloro-2- (2,4- Chlorophenoxy) phenol is included in an amount of 0.01 to 5.0% by weight based on the total weight of the antibacterial plastic.

The antimicrobial plastic is an antimicrobial master comprising 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one, 5-chloro-2- (2,4-chlorophenoxy) phenol, and synthetic resin May contain a master batch. In this case, the 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one is contained in 0.01 to 5.0% by weight based on the total weight of the antibacterial plastic, the 5-chloro-2- (2, 4-chlorophenoxy) phenol is included at 0.01 to 5.0% by weight based on the total weight of the antibacterial plastic.

According to another embodiment of the present invention, an oil paint, 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one, and 5-chloro-2- (2,4-chlorophenoxy ) Provides an antibacterial oil paint containing phenol. The 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one is included in an amount of 0.01 to 5.0 wt% based on the total weight of the antibacterial oil paint, and the 5-chloro-2- (2,4 -Chlorophenoxy) phenol is contained in an amount of 0.01 to 5.0% by weight based on the total weight of the antibacterial oil paint.

Antimicrobial plastics and antimicrobial oil paints of the present invention have an excellent antimicrobial activity to gram positive bacteria, gram negative bacteria, and molds, while containing a smaller amount of antimicrobial agents than before, and the antimicrobial activity is maintained for a long time even in the presence of a large amount of water. Excellent antibacterial activity against strains, less harmful to human body.

In addition, according to the manufacturing method of the antimicrobial plastics according to an embodiment of the present invention, it is easy to handle the antimicrobial agent and mixing with the synthetic resin, there is no problem of scattering dust to improve the productivity.

Hereinafter, the present invention will be described in more detail.

Antibacterial plastic according to an embodiment of the present invention is a synthetic resin, 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one (4,5-dichloro-2-n-octyl-4-isothiazoline -3-one, DCOIT), and 5-chloro-2- (2,4-chlorophenoxy) phenol (5-chloro-2- (2,4-dichlorophenoxy) phenol, triclosan).

The antimicrobial plastic includes a synthetic resin and an antibacterial master batch including DCOIT, triclosan and synthetic resin, wherein the DCOIT is contained in an amount of 0.01 to 5.0% by weight based on the total weight, and the triclosan is 0.01% by weight. To 5.0 wt%.

Antibacterial oil paint according to another embodiment of the present invention includes an oil paint, DCOIT, and triclosan. The antimicrobial oil paint includes DCOIT in an amount of 0.01 to 5.0 wt% based on the total weight, and triclosan in an amount of 0.01 to 5.0 wt% based on the total weight.

The DCOIT and triclosan have non-polar hydrophobic properties due to their chemical structural properties, so they are easily mixed with oil-based paints using the same hydrophobic plastic and hydrophobic organic solvents, and are uniformly dispersed to provide uniform antimicrobial activity on the surface of plastics or oil paints. To show. In addition, the DCOIT and triclosan are not easily eluted by moisture, etc., even when incorporated into plastics and oil paints to maintain a continuous antibacterial activity.

The antimicrobial plastic and the antimicrobial oil paint include the DCOIT in an amount of 0.01 to 5.0% by weight based on the total weight, and the triclosan in an amount of 0.01 to 5.0% by weight based on the total weight. .

Many antimicrobial products have been released in the past to attract the attention of consumers, but did not show the actual antimicrobial power as consumers feel. Antimicrobial products should kill all fungi, gram-positive bacteria, and gram-negative bacteria and exhibit sustained antimicrobial activity. However, most antimicrobial products act specifically on certain fungi and do not exhibit extensive antimicrobial activity on all microorganisms. Each microorganism survives through its own specific metabolic process, and one antimicrobial agent is unlikely to work on all microorganisms.

In addition, most of the antimicrobial agents are almost all water-soluble, so that the antimicrobial component is dissolved in water and eluted out of the injection molding where it is wet, and thus the antimicrobial activity is lost within a relatively short time.

However, the antimicrobial plastic and the antimicrobial oil paint have broad antimicrobial activity by using DCOIT having excellent antimicrobial activity against mold and gram positive bacteria and triclosan having excellent antimicrobial activity against gram positive bacteria and gram negative bacteria. In addition, since the DCOIT and triclosan are insoluble in water, the antimicrobial plastic and the antimicrobial oil paint are particularly useful when used in an environment in which a large amount of water is present, and the antimicrobial activity is maintained for a long time.

The DCOIT (CAS No .: 64359-81-5) is the molecular weight 282.2274g / mol, molecular formula is C ₁₁ H ₁₇ C _l2 NOS. Since the cell walls of bacteria or fungi carry active transport using adenosine triphosphate (ATP) energy when absorbing the DCOIT, DCOIT is rapidly absorbed and exhibits rapid antimicrobial activity.

1 shows that DCOIT is brewer's yeast ( Saccharomyces) cerevisiae ) is a graph showing the amount absorbed by the cell wall over time. Referring to Figure 1, DCOIT is quickly absorbed into the cell wall is present in a large amount inside the cells of the microorganisms within a short time, and inhibits the growth of the microorganisms to quickly exhibit the antibacterial power that the antimicrobial plastic or antimicrobial oil paint should have. Can be.

DCOIT absorbed through the cell wall inhibits microbial oxygen respiration, inhibits microbial growth, inhibits ATP production, and inactivates various enzymes to kill microorganisms. Figure 2 is Escherichia coli after the addition of DCOIT coli ) is a graph showing the extent to which oxygen respiration is suppressed. Referring to FIG. 2, it can be seen that the oxygen breathing of E. coli rapidly decreases within a few minutes after administration of DCOIT, thereby rapidly killing E. coli.

In addition, DCOIT reacts with thiol groups of dehydrogenases to destroy and inactivate dehydrogenases. Dehydrogenases are essential enzymes for the metabolism of microorganisms after nutrients. Thus, inactivation of dehydrogenase inhibits the energy metabolism of microorganisms and thus inhibits ATP energy production in cells. As a result, the energy in the cells is depleted and the microorganisms are killed. Figure 3 is a graph showing the change in activity after the addition of DCOIT to alcohol dehydrogenase. Referring to Figure 3, it can be seen that the activity of the alcohol dehydrogenase is rapidly reduced after the addition of DCOIT.

In addition, DCOIT increases the free radicals in the cell, destroying the cell's components, and killing microorganisms by losing the cell's self-regulation ability.

The triclosan (CAS No .: 3380-34-5) has a molecular weight of 289.53 g / mol, and a molecular formula is C ₁₂ H ₇ Cl ₃ O ₂ . The triclosan inactivates Enoyl-acyl carrier protein reductase. The enoyl-acyl carrier protein reductase is a key enzyme for producing fatty acids of microbial cells and fatty acids are the main components of cell membranes. The triclosan binds 1: 1 with the anoyl-acyl carrier protein reductase to permanently inactivate the anoyl-acyl carrier protein reductase, thereby inhibiting the production of fatty acids. As a result, cell membrane formation becomes impossible and the cells die. Since the enoyl-acyl carrier protein reductase is present in all microorganisms, the triclosan shows antimicrobial activity against a wide range of bacterial species.

Synthetic resin included in the antimicrobial plastics can be used as long as it can be injection molded, polyethylene (PE), polypropylene (PP), polystyrene (PS), styrene / acrylonitrile / butadiene (ABS), polyamide ( PA), polyoxymethylene (POM), polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate (PMMA), polycarbonate (PC), PC alloy, etc. can be used. However, the present invention is not limited thereto.

In addition, the synthetic resin included in the antimicrobial masterbatch polyethylene (PE), polypropylene (PP), polystyrene (PS), styrene / acrylonitrile / butadiene (ABS), polyamide (PA), polyoxymethylene (POM) , Polyethylene terephthalate (PET), polybutylene terephthalate (PBT), polymethyl methacrylate (PMMA), polycarbonate (PC), PC alloy (PC Alloy) and the like, but the present invention is not limited thereto. no.

Synthetic resin included in the antimicrobial plastic and synthetic resin included in the antimicrobial masterbatch may use the same synthetic resin. In this case, the antimicrobial masterbatch and the synthetic resin have the same physical properties, thereby facilitating mixing.

The oil paints included in the antimicrobial oil paints include oil paints, oil enamels, alkyd resins, amino alkyd resins, acrylic resins, phenol resins, epoxy resins, unsaturated polyester resins, polyurethane resins, and the like. Although it may be used, the present invention is not limited thereto.

The antimicrobial plastic and the antimicrobial oil paint have high antimicrobial activity through the action of DCOIT destroying dehydrogenase in microbial cells and the action of triclosan inhibiting the activity of the anoyl-acyl carrier protein reductase to inhibit fatty acid production. Including DCOIT in an amount of 0.01 to 5.0% by weight based on the total weight of the antimicrobial plastics, and incorporating the triclosan in an amount of 0.01 to 5.0% by weight, based on the total weight of the antimicrobial plastics, the DCOIT and triclosan are synergistic to be sufficient even at a lower concentration than before. It shows antibacterial activity.

All microorganisms are often resistant to at least one antimicrobial agent. In addition, when one antimicrobial agent is used for a long time, a strain with resistance necessarily appears, and in this case, the antimicrobial activity begins to decrease rapidly. However, the antimicrobial plastic and antimicrobial oil paint can solve this problem by using DCOIT and triclosan in the content range. That is, since the occurrence of strains that are resistant to two antimicrobial agents at the same time is extremely difficult, there is little concern about resistance expression even when using the antimicrobial plastic for a long time.

In addition, securing a wide range of antimicrobial properties is an essential requirement for antimicrobial products. The DCOIT shows a strong antimicrobial activity mainly on fungi and algae, triclosan mainly shows a strong antimicrobial activity against gram positive and gram negative bacteria. However, unusual fungi and algae are more easily killed by triclosan than DCOIT, and unusual gram positive and gram negative bacteria are more easily killed by DCOIT than triclosan. Therefore, the antimicrobial plastic and the antimicrobial oil paint can secure the effect of killing a wider range of microorganisms by using DCOIT and triclosan in the content range.

Antimicrobial products should maintain long-term antimicrobial activity. In particular, in order to maintain the long-term antimicrobial activity in the environment where there is a lot of moisture, it is possible that the leaching of the antimicrobial agent contained in the antimicrobial product is extremely weak. If a water-soluble antimicrobial agent is used in an environment where there is a lot of water, the antimicrobial agent will soon elute and disappear. However, DCOIT has a solubility in water of about 2 ppm at room temperature and triclosan of about 5 to 10 ppm, so that it is insoluble in water. The antimicrobial plastic and the antimicrobial oil paint contain the DCOIT and triclosan in the above contents, thereby maintaining the antimicrobial activity for a long time even when used in a wet environment.

In addition, the antimicrobial plastics and the antimicrobial oil paint includes DCOIT and triclosan in the above contents, thereby having excellent antimicrobial activity and excellent safety. The DCOIT and triclosan itself are not only safe substances, but also less harmful to the human body when used in the content range. The DCOIT is an antimicrobial agent approved by the US Food and Drug Administration (FDA) for use in food packaging, and triclosan is a quasi-drug that is generally used in toothpaste, cosmetics, or skin ointment, and is a relatively safe antibacterial agent to the human body.

The antimicrobial plastic may be molded in various forms, and may be used as an antimicrobial drain, an antibacterial bin, an antibacterial air duct, an antibacterial hose, or an antibacterial pipe, but the present invention is not limited thereto.

The antimicrobial plastics may be prepared by mixing synthetic resin raw materials with DCOIT and triclosan, followed by polymerization, and the antimicrobial oil paint may be prepared by adding DCOIT and triclosan to an oil paint.

In addition, the antimicrobial plastic is put into the reaction vessel and pulverized synthetic resin and DCOIT and triclosan and stirred at 60 to 80 ℃, to prepare an antimicrobial masterbatch in the form of pellets, after adding the prepared antimicrobial masterbatch to the synthetic resin, It can be produced by molding. As the molding method, any plastic molding method can be used, and compression molding, injection molding, extrusion molding, air blow molding, thermoforming, hot melt molding, foam molding, roll molding, or reinforced plastic molding may be used. Although it may be used, the present invention is not limited thereto.

The content of DCOIT and triclosan in the preparation of the antimicrobial masterbatch and the content of the antimicrobial masterbatch when the antimicrobial masterbatch is added to the synthetic resin are controlled so that the content of DCOIT and triclosan in the final antimicrobial plastic is 0.01 to 5.0% by weight, respectively. can do.

According to the manufacturing method of the antimicrobial plastics, by preparing and mixing the antimicrobial agent in a master batch, it is easy to mix and handle with the synthetic resin, there is no problem of scattering dust to improve the productivity.

Hereinafter, preferred examples and comparative examples of the present invention are described. However, the following examples are only preferred embodiments of the present invention and the present invention is not limited to the following examples.

(Production of antibacterial oil paint)

The antimicrobial activity of DCOIT, Triclosan, and antimicrobial paints using DCOIT and Triclosan were measured by the paper disk method. At this time, the strain is Escherichia coli which is a gram negative bacteria coli ) was used.

( Reference Example  One)

30 wt% of an oily acrylic binder, 35 wt% of xylene, 34.5 wt% of toluene, 0.2 wt% of an acrylic dispersant, 0.1 wt% of a viscosity modifier, and 0.2 wt% of DCOIT were mixed and stirred for 30 minutes to prepare an antimicrobial oil paint. The antimicrobial oil paint prepared above was adsorbed on a paper disk. Meanwhile, after adding a bacterial culture solution (100-fold dilution) to nutrient agar (NA) medium, 2ml each was inoculated into the medium. The paper disks were placed on nutrient agar medium and incubated in a 30 ° C. incubator for 3 days.

( Reference Example  2)

Triclosan was replaced with DCOIT in Reference Example 1, except that the total content of the antimicrobial agent was 0.2% by weight.

( Example  One)

In Reference Example 1, DCOIT was used at 0.1 wt%, and triclosan was used at 0.1 wt%, except that the total content of the antimicrobial agent was 0.2 wt%.

(Antimicrobial Activity Test Result of Antibacterial Oil Paint)

The growth results of the microorganisms cultured in Reference Example 1, Reference Example 2, and Example 1 are shown in FIGS. 4 to 6. 4 to 6, it can be seen that in the case of Example 1, a wider low band was formed than in Reference Examples 1 and 2. In addition, in the case of Example 1, the total content of the antimicrobial agent is 0.2% by weight, which is the same as the total content of the antimicrobial agents of Reference Examples 1 and 2, but it can be seen that a lower zone is formed wider than that of Reference Examples 1 and 2. That is, it can be seen that the antimicrobial activity was enhanced by using DCOIT and triclosan together.

(Manufacture of antibacterial plastic)

( Reference Example  3)

The crushed ABS resin and DCOIT were put in a reaction vessel and mixed at a temperature of 60 ° C., and then molded into pellets to prepare an antibacterial masterbatch. The prepared antimicrobial masterbatch was added to the crushed ABS resin, and the ABS resin including the antimicrobial masterbatch was injection molded to prepare an antimicrobial plastic. At this time, the content of the DCOIT was adjusted to 0.3% by weight relative to the total weight of the antibacterial plastic.

( Reference Example  4)

An antimicrobial plastic was prepared in the same manner as in Reference Example 3 except that triclosan was used instead of DCOIT as the antimicrobial agent in Reference Example 3. At this time, the content of the triclosan was adjusted to 0.3% by weight relative to the total weight of the antibacterial plastic.

( Example  2)

An antimicrobial plastic was prepared in the same manner as in Reference Example 3 except that DCOIT and triclosan were used as the antimicrobial agents in Reference Example 3. At this time, the content of the DCOIT was adjusted to 0.1% by weight relative to the total weight of the antimicrobial plastic, the content of the triclosan was adjusted to 0.1% by weight relative to the total weight of the antimicrobial plastic.

(Antibacterial activity test result of antibacterial plastic)

Reference Example 3, Reference Example 4, and Example 2 Staphylococcus aureus of the prepared antimicrobial plastic (S. aureus), Escherichia coli, and fungi (Asp. Niger) were measured through a low-lying areas to form the antimicrobial activity of each test bacteria in.

Staphylococcus aureus or Escherichia coli culture (100-fold dilution) was added to the nutrient agar medium, and then 2 ml each was inoculated into the medium. The prepared antimicrobial plastics were placed on nutrient agar medium, and then cultured in a 30 ° C. incubator for 3 days. In the case of mold, the same procedure was performed as in the case of Staphylococcus aureus or Escherichia coli, except that potato agar (potato dextrose agar, PDA) medium was used instead of nutrient agar medium.

The bacterial low zone formation test results of Reference Example 3 are shown in FIGS. 7 to 9, the bacterial low zone formation test results of Reference Example 4 are shown in FIGS. 10 to 12, and the bacterial low zone formation test results of Example 2 are shown in FIGS. 13 to 15. Shown in

7 to 9, the antimicrobial plastics of Reference Example 3 showed antibacterial activity against Staphylococcus aureus and mold, but did not show antibacterial activity against Escherichia coli.

10 to 12, it can be seen that the antimicrobial plastic of Reference Example 4 showed antibacterial activity against Staphylococcus aureus and Escherichia coli but no antibacterial activity against mold.

13 to 15, the antimicrobial plastics of Example 2 showed even antibacterial activity against all bacteria and molds, although the total antimicrobial content was less than Reference Examples 3 and 4. That is, by using a mixture of DCOIT and triclosan, it was possible to secure a strong antimicrobial activity against a wide range of microorganisms with a smaller amount of antimicrobial agent.

All simple modifications or changes of the present invention can be easily carried out by those skilled in the art, and all such modifications or changes can be seen to be included in the scope of the present invention.

1 is a graph showing the amount of DCOIT absorbed to the cell wall of brewer's yeast over time.

Figure 2 is a graph showing the extent to which oxygen breathing of E. coli is suppressed after DCOIT.

Figure 3 is a graph showing the change in activity after injecting DCOIT to alcohol dehydrogenase.

Figure 4 is a photograph showing the growth results of the microorganisms cultured in Reference Example 1.

5 is a photograph showing growth results of microorganisms cultured in Reference Example 2. FIG.

Figure 6 is a photograph showing the growth results of the microorganisms cultured in Example 1.

7 to 9 are photographs showing the bacterial low zone formation test results for Staphylococcus aureus, Escherichia coli, and mold of the antibacterial plastic prepared in Reference Example 3.

10 to 12 are photographs showing the bacterial low zone formation test results for Staphylococcus aureus, Escherichia coli, and mold of the antibacterial plastic prepared in Reference Example 4.

Figures 13 to 15 are photographs showing the bacterial low zone formation test results for Staphylococcus aureus, Escherichia coli, and mold of the antibacterial plastic prepared in Example 2.

Claims (3)

delete delete Oil paint, 4,5 dichloro-2-n-octyl-4-isothiazoline-3-one, and 5-chloro-2- (2,4-chlorophenoxy) phenol; The 4,5-dichloro-2-n-octyl-4-isothiazoline-3-one is contained in an amount of 0.01 to 5.0 wt% based on the total weight, and the 5-chloro-2- (2,4-chlorophenoxy C) an antimicrobial oil-based paint comprising 0.01 to 5.0% by weight of phenol.

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