KR100841021B1 - Apparatus and method for microparticle manipulation using flat display and condenser lens - Google Patents

Abstract

An apparatus and a method for driving micro-particles using a flat panel display and a lens are provided to remove dispersion caused by diffraction of light by condensing and applying an image irradiated from the flat panel display by using the lens and form light, applied through an arbitrary pattern, as a clear driving image with high resolution on a photoconductive layer. A flat panel display(10) irradiates light. A lens(20) condenses light outputted from the flat panel display. A photoconductive layer(30) applies voltage to an area where the light is condensed by the lens. A ground layer(40) forms an electric field in the photoconductive layer. A micro-fluid channel(50) moves solid particles within micro-fluid through the voltage applied to the condensed area of the photoconductive layer.

Description

Apparatus and Method for Microparticle Manipulation Using Flat Display and Condenser Lens}

1 is a perspective view schematically showing a fine particle driving apparatus using a flat panel display and a lens according to the present invention.

Figure 2 is a perspective view schematically showing the optical refraction of the microparticle drive device using a flat panel display and a lens according to the present invention.

Figure 3 is a perspective view schematically showing the movement of microparticles by electrophoresis in the microparticle drive apparatus using a flat panel display and a lens according to the present invention.

Figure 4 is a perspective view schematically showing the movement of the fine particles by the negative electrophoresis in the microparticle drive apparatus using a flat panel display and a lens according to the present invention.

Figure 5 is a perspective view schematically showing the movement of the microparticles by positive electrophoresis in the microparticle drive device using a flat panel display and a lens according to the present invention.

6A is a perspective view schematically illustrating a shape in which a pattern is incident in a microparticle driving apparatus using a flat panel display according to the related art.

6B is a perspective view schematically illustrating a shape in which a pattern is incident on a microparticle driving device using a flat panel display and a lens according to the present invention;

Figure 7 is a graph showing the microparticle drive speed according to the microparticle radius of the microparticle drive device and the prior art microparticle drive device using a flat panel display and a lens according to the present invention.

8 is a flow chart schematically showing a method for driving fine particles using a flat panel display and a lens according to the present invention.

        <Brief description of reference numerals for the main parts of the drawings>

1: Fine particle driving device using flat panel display and lens

10: flat panel display 20: lens

30: photoconductive layer 40: ground layer

50: microfluidic flow path 60: power source

The present invention relates to a microparticle driving device and a driving method using a flat panel display and a lens, and more particularly, by collecting and incident an image irradiated from the flat panel display using a lens, thereby eliminating dispersion due to diffraction of light. Therefore, the light incident in an arbitrary pattern forms a driving image with distinct and high resolution on the photoconductive layer, thereby moving the microparticles inside the microfluid at a desired position, and having a high numerical aperture and a short focal length. The present invention relates to a microparticle driving apparatus and a driving method using a flat panel display and a lens that can be manufactured to have high portability and high efficiency compared to a manufacturing cost by using a condensing lens having a.

In general, Dielectrophoresis (DEP) is a method in which dielectric particles exhibit inductive dipoles in a non-uniform electric field, and use them to move the dielectric particles.

In addition, the dielectrophoresis is a method of freely controlling solid particles in the fluid, and the movement of the particles due to the electrophoresis is changed according to the frequency of the applied alternating voltage, the type of the fluid, and the type of the solid particles. It is composed of negative (-) dielectric movement in the weak direction and positive (+) dielectric movement in which the particles move in the strong direction of the electric field.

Here, the microparticle driving device is a method of moving fine grains and living cells by using the above-mentioned electrophoresis, and applying a voltage only to a specific region to which the pattern is irradiated using a photoconductive layer and a light source, thereby applying a voltage to the pattern. Accordingly, the particles can be moved, and include a ground layer as ground for generating a potential difference and a photoconductive layer to which a voltage according to a pattern is applied.

However, when the light irradiated from the light source reaches the photoconductive layer spaced by a certain distance, the pattern cannot be clearly irradiated with the scattered blur image due to the diffraction of the light, and thus the driving image with low resolution As well as difficult to drive the microparticles in the microfluidic at the desired position, there was a problem that the driving performance is significantly reduced.

The present invention has been made to solve the above problems, by collecting and incident the image irradiated from the flat panel display using a lens, thereby eliminating the dispersion phenomenon due to the diffraction of light, and thus the light incident in an arbitrary pattern The photoconductive layer can be formed into a driving image with clear and high resolution, and can move microparticles inside the microfluid at a desired position, and it has high portability by using a condenser lens having a high numerical aperture and a short focal length. It is an object of the present invention to provide a microparticle driving device and a driving method using a flat panel display and a lens that can be manufactured to have high efficiency with respect to manufacturing cost.

The present invention to achieve the object as described above is a flat panel display for irradiating light; A lens for condensing light output from the flat panel display; A photoconductive layer to which a voltage is applied to a region focused by the lens; A ground layer for forming a potential in the photoconductive layer; A microfluidic flow path for moving solid particles in the microfluid at a voltage applied to the focused region of the photoconductive layer; It includes.

Here, the lens is made of a condenser lens for injecting any pattern of light incident from the flat panel display into the photoconductive layer, wherein the focal point of any pattern is optimal for condensing on the photoconductive layer. It is characterized in that provided in the position.

In addition, the lens is characterized in that provided between the flat panel display and the photoconductive layer.

And, when the solid particles in the microfluidic charge is characterized in that the movement by electrophoresis.

In addition, when the solid particles in the microfluid do not have a charge, the microparticles are characterized in that they are moved by dielectrophoresis.

Here, the microfluidic and the microelectrophoresis of the microparticles in the microfluidic can be changed by the frequency of the applied alternating voltage.

And, the solid particles in the microfluidic can be moved to the fluid flow by the alternating electrical osmosis (Electroosmosis).

In addition, the flat panel display includes a light and light pattern forming apparatus capable of forming an arbitrary pattern to irradiate light to apply a voltage to the pattern region with the photoconductive layer and to adjust the contrast of the arbitrary pattern; Characterized in that it comprises a.

In addition, the flat panel display is characterized by applying one of LCD, PDP or OLED.

Here, the photoconductive layer is characterized in that the voltage is applied by the photo transistor in the area irradiated with the light output from the flat panel display.

In addition, the voltage applied to the photoconductive layer is characterized in that the AC voltage.

In this case, the photoconductive layer and the ground layer are transparent electrodes formed of indium tin oxide (ITO), which is a transparent electrode on a glass substrate; Amorphous silicon deposited on the transparent electrode; Silicon nitride deposited on the amorphous silicon; Characterized in that comprises a.

Here, the amorphous silicon is characterized in that the intrinsic hydrogenated amorphous silicon intrinsic a-Si: H is deposited on the n + a-Si: H hydrogenated n-type amorphous silicon.

On the other hand, condensing light emitted from the flat panel display forming an arbitrary pattern using a lens; Applying a voltage by a ground layer provided to form a photo transistor and a potential of the photoconductive layer in a region irradiated with light refracted and collected by the lens; Moving solid particles in the microfluid in a region to which the voltage of the photoconductive layer is applied; It includes.

Here, when the solid particles in the microfluidic charge is characterized in that the movement by electrophoresis.

In this case, when the solid particles in the microfluid do not have a charge, the microparticles may be moved by dielectrophoresis.

In addition, the dielectric fluid of the microfluid and the microparticles in the microfluid may be changed at a frequency of an applied AC voltage.

In addition, the solid particles in the microfluidic is characterized in that can be moved to the fluid flow by alternating electrical osmosis (Electroosmosis).

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a perspective view schematically showing a fine particle driving apparatus using a flat panel display and a lens according to the present invention. As shown in the drawings, the microparticle driving apparatus 1 using the flat panel display and the lens according to the present invention includes a flat panel display 10, a lens 20, a photoconductive layer 30, and a ground layer (GND, 40). ) And the microfluidic flow path 50 and the power supply 60.

Here, the flat panel display 10 further includes a contrast pattern forming apparatus (not shown) for forming a contrast in a region and a shape desired by a user. The lens 20, the photoconductive layer 30, and the ground layer 40 may be formed. The patterns are arranged in parallel to each other so that the patterns formed in the light and dark pattern forming apparatus (not shown) are incident on the light shining area.

To this end, the flat panel display 10 may be applied to a liquid crystal display (LCD), a plasma display panel (PDP), an organic light emitting diode (OLED), or the like, and forms a pattern desired by a user with a predetermined signal. It is also preferable to replace it with a device capable of injecting light into the illuminated part, and forming a light in the area where the pattern shines and a dark part in the other part.

For example, the flat panel display 10 may irradiate light to a region and a pattern desired by a user by a light source or a self-luminous light, and the region and the pattern may be a microparticle driving apparatus using a flat panel display and a lens 1. ), The user wants a pattern called 'KAIST', and thus forms a pattern called 'KAIST', so that light having a shape having the pattern of 'KAIST' It is made to be irradiated with the lens 20, the photoconductive layer 30, the ground layer 40, which may be variously modified according to the purpose.

The flat panel display 10 according to the present invention is described by applying a liquid crystal display (LCD).

Here, the flat panel display 10, which is the liquid crystal display (LCD), is a device that changes and transmits an electrical signal to visual information by using a change in liquid crystal transmittance according to an applied voltage. However, when the power consumption is low and easy to carry, and the voltage according to the signal desired by the user is applied to the liquid crystal, the arrangement of the liquid crystal is changed. Accordingly, when the light source is transmitted, diffraction occurs and transmitted through the polarizer to obtain a desired image. have.

In addition, the plasma display panel (PDP) applicable to the flat panel display 10 includes a plurality of small cells disposed between two thin glass plates, and generates ultraviolet rays such as neon and argon between electrodes mounted above and below. It can be applied to the present invention because it can be obtained by self-luminescence to obtain an image, and easy to carry.

In addition, the OLED (Organic Light Emitting Diodes) applicable to the flat panel display 10 is a self-luminous type organic diode using an electroluminescence phenomenon that irradiates light by inputting a current to a fluorescent organic compound, and with low manufacturing cost and flexibility. It is easy to manufacture and carry, and can be applied to the present invention because the user can output a desired image according to the input current.

It is possible to implement an imaging device integrating the light source 10 and the contrast pattern forming apparatus 20, and to use a device capable of forming a contrast of a specific pattern in addition to the LCD, PDP, and OLED, and irradiating a light source. desirable.

When the light is irradiated to a pattern and an area desired by the user, the lens 20 is provided to be focused and irradiated to the photoconductive layer 30 and the ground layer 40 without being dispersed according to the diffraction of the light. .

To this end, the lens 20 is made of a condenser lens, which is not intended to form an image for the light irradiated to the pattern and the area desired by the user, but rather to transmit light to the photoconductive layer 30. ) And is used to concentrate the ground layer 40, and can increase the resolution of light irradiated to a pattern and an area desired by a user, and can refract the light.

Therefore, the diffusion phenomenon due to the diffraction of light, and thus the blur (Blur) is provided to prevent, for example, a pattern of 'KAIST' having a width of 30μm in the flat panel display 10, the lens 20 When irradiated without passing through, the photoconductive layer 30 has a width of 300 μm, that is, a blur image is dispersed more than twice the width of the original image so that a blur image is formed on the photoconductive layer 30 and the ground layer. The image is irradiated to (40), and the image of 'KAIST' having a blurred 300 μm width is irradiated instead of the pattern of 'KAIST' having a width of 30 μm desired by the user. Accurate driving may not be possible, and light below a threshold light quantity that may drive the photodiode included in the photoconductive layer 30 may be incident to prevent a voltage from being applied thereto. Area As it is not clear, the electric field slope is greatly lowered, which may drastically reduce the driving performance of the fine particles.

Accordingly, the lens 20 is configured to irradiate stronger light by condensing the original image, and the size of the pattern can be irradiated with a pattern of 'KAIST' having a smaller width by the magnification of the lens. The voltage can be applied to light above a threshold light quantity that can drive the photodiode included in the photoconductive layer 30, and the boundary of the region to which the voltage is applied is increased to increase the slope of the electric field. It enables to drive the fine particles smoothly.

In addition, the lens 20 includes a lens 20 having a high numerical aperture that determines the resolution, and as the numerical aperture increases, more light beams are used, so that a user desires an area and a pattern. The light irradiating the light becomes brighter, and the resolution for identifying two adjacent points is also increased, and the lens 20 is provided to have a short focal length so that the lens 20 includes the flat panel display 10 and the photoconductive layer ( Even if it is inserted between 30) the overall size of the microparticle drive device 1 using the flat panel display and the lens according to the present invention does not become large, so that it is easy to carry.

The photoconductive layer 30 includes a photo transistor (not shown) to apply a voltage to the pattern and the region where the light is incident when the light of the pattern and the region desired by the user is incident through the lens 20. It is done by

The photo transistor is a transistor in which a base-emitter junction is used for a PN junction of a photodiode. The photo transistor includes a case formed of glass so as to respond to external light, and a predetermined amount of light is irradiated. If so, a voltage can be applied.

In addition, the photoconductive layer 30 is made of amorphous silicon, a transparent electrode formed of indium tin oxide (ITO) which is a transparent electrode on a glass substrate, amorphous silicon deposited on the transparent electrode, Silicon nitride (Silicon Nitride) deposited on the amorphous silicon is sequentially formed.

In addition, the amorphous silicon is n + a-Si: H, which is a hydrogenated n-type amorphous silicon (n + Doped Hydrogenated Amorphous Silicon) deposited on the transparent electrode at a predetermined thickness, and the hydrogenated n-type amorphous silicon (Intrinsic Hydrogenated Amorphous Silicon) ) And intrinsic a-Si: H which is intrinsic hydrogenated amorphous silicon deposited on n + a-Si: H.

In addition, the ground layer 40 is provided to serve as a ground (GND) so that a potential is formed in the photoconductive layer 30, and has the same configuration as the photoconductive layer 30.

Here, an AC power source 50 is provided to apply an AC voltage to the photoconductive layer 30 and the ground layer 40 to form a potential desired by the user. The frequency of the AC power source is included in the microfluid. It can be adjusted according to the size and type of solid particles.

In addition, when a voltage is applied to the photoconductive layer 30, the ground layer 40 is configured to play a role of ground (GND). On the contrary, when a voltage is applied to the ground layer 40, the photoconductive layer is applied. 30 may be modified to perform the role of ground GND.

In addition, the microfluidic flow path 50 is formed between the photoconductive layer 30 and the ground layer 40 so that the microparticles or solid particles in the microfluid can be moved and aligned.

As described above, the light is irradiated into a region and a pattern to which voltage is applied by using an imaging device such as the flat panel display 10 (1), and the light is emitted from the lens 20 to condense the photoconductive layer 30. (2), the power is supplied so that the voltage of the power source 50 is conducted in the pattern and the region of the photoconductive layer 30 and the ground layer 40 by using the light irradiated to the desired pattern and the region. When the photo transistor of the photoconductive layer 30 converts the light into a voltage, the solid particles in the microfluidic fluid are solidified in accordance with the applied voltage and the shadow of the irradiated light pattern. And aligned in the microfluidic flow path between the ground layer 40 is moved in the direction desired by the user (④).

Figure 2 is a perspective view schematically showing the optical refraction of the microparticle drive device using a flat panel display and a lens according to the present invention. As shown in the figure, the microparticle drive device 1 using the flat panel display and the lens according to the present invention outputs the light of the greatest intensity at the right end of the flat panel display 10, It is assumed that the light of the weakest intensity is output at the left end, and the light of the medium intensity is output at the center of the flat panel display 10.

Here, since the lens 20 uses a condenser lens, light of a pattern and a region desired by a user is collected and refracted, respectively, and incident on the photoconductive layer 30.

That is, when light is irradiated to a region and a pattern to which voltage is applied using an imaging device such as the flat panel display 10 (①), the light emitted from the lens 20 is concentrated and output to the photoconductive layer 30. At this time, the light of the greatest intensity output from the right end is refracted and irradiated to the left end of the photoconductive layer 30, and the light of the weakest intensity output from the left end is the photoconductive layer 30. It is refracted to the right end of) and irradiated.

In this way, the lens 20 can clearly form an image of the flat panel display 1 for driving microparticles and solid particles in the microfluid by removing dispersion and blur due to diffraction of light. As a result, a large electric field gradient can be formed, and thus a large force can be applied to the microparticles.

In addition, the amount of light irradiated from the flat panel display 10 may be transmitted to the photoconductive layer 30 without loss, thereby increasing the voltage change of amorphous silicon inside the phototransistor (not shown) layer in response to the amount of light. Therefore, it is possible to effectively control the microparticles and solid particles in the microfluid.

In addition, the image pattern irradiated from the flat panel display 10 may be adjusted in size by the magnification of the lens 20, and thus the microparticles and the solid particles in the microfluid may be effectively controlled by the condensed and reduced image patterns. .

In addition, the height of the lens 10 may be adjusted to adjust the focus of the image pattern emitted from the flat panel display 10.

3 is a perspective view schematically showing the movement of microparticles by electrophoresis in the microparticle driving apparatus using a flat panel display and a lens according to the present invention. As shown in the drawing, the microparticle driving apparatus 1 using the flat panel display and the lens according to the present invention irradiates light into an area and a pattern to which voltage is applied using an imaging apparatus such as the flat panel display 10. (①).

When the light emitted from the lens 20 is collected and output to the photoconductive layer 30 (②), the photoconductive layer 30 and the ground layer are formed by using light irradiated in a pattern and an area desired by a user. Power is applied to conduct the voltage of the power source 50 in the pattern and region of 40 (3), and when the phototransistor of the photoconductive layer 30 changes the light to voltage, the applied voltage and irradiated light The solid particles in the microfluid are aligned between the photoconductive layer 30 and the ground layer 40 according to the shading according to the pattern of (4).

Here, assuming that a positive voltage is formed in the photoconductive layer 30, and the microparticles and the solid particles in the microfluidic state have a positive charge, the repulsive force causes repulsion. The fine particles and the solid particles in the microfluid are moved in the direction of the ground layer 40.

Figure 4 is a perspective view schematically showing the movement of the microparticles by the negative electrophoresis in the microparticle drive apparatus using a flat panel display and a lens according to the present invention. As shown in the figure, the microparticle drive device 1 using the flat panel display and the lens according to the present invention moves the solid particles in the microfluidic to the negative electrophoresis.

Here, the light irradiated from the flat panel display 10 is irradiated in a pattern or a region desired by a user, and the light is irradiated into a region and a pattern to apply voltage from the photoconductive layer 30 and the ground layer 40 (①). .

When the light emitted from the lens 20 is collected and output to the photoconductive layer 30 (②), the photoconductive layer 30 and the ground layer are formed by using light irradiated in a pattern and an area desired by a user. Power is applied to conduct the voltage of the power source 50 in the pattern and region of 40 (3), and when the phototransistor of the photoconductive layer 30 changes the light to voltage, the applied voltage and irradiated light The microfluidic particles or the solid particles in the microfluid are aligned between the photoconductive layer 30 and the ground layer 40 according to the shading according to the pattern of (4).

Here, if (+) voltage is formed in the photoconductive layer 30, and the microparticles and the solid particles in the microfluid are not charged, the microparticles and the solid particles in the microfluid are caused by the electric dipole induction phenomenon. Is formed in the form of an electric dipole, and the microparticles and the solid particles in the microfluid are formed by a negative dielectric action that moves to the ground layer 40 having a weak electric field, that is, a relatively weak electric potential. It moves in the direction of the ground layer 40 (⑤).

Figure 5 is a perspective view schematically showing the movement of the fine particles by the positive electrophoresis in the microparticle drive apparatus using a flat panel display and a lens according to the present invention. As shown in the figure, the microparticle drive device 1 using the flat panel display and the lens according to the present invention moves the microparticles and the solid particles in the microfluidic to positive dielectrophoresis.

Here, the light irradiated from the flat panel display 10 is irradiated in a pattern or a region desired by a user, and the light is irradiated into a region and a pattern to apply voltage from the photoconductive layer 30 and the ground layer 40 (①). .

When the light emitted from the lens 20 is collected and output to the photoconductive layer 30 (②), the photoconductive layer 30 and the ground layer are formed by using light irradiated in a pattern and an area desired by a user. The power is applied to conduct the voltage of the power supply 50 in the pattern and region of 40 (③), and when the phototransistor of the photoconductive layer 30 changes the light to voltage, the applied voltage and irradiated light The solid particles in the microfluid are aligned between the photoconductive layer 30 and the ground layer 40 according to the shading according to the pattern of (4).

Here, if (+) voltage is formed in the photoconductive layer 30, and the microparticles and the solid particles in the microfluid are not charged, the microparticles and the solid particles in the microfluid are caused by electric dipole induction. Is formed in the form of an electric dipole, and the microparticles and the solid particles in the microfluid are formed by positive electrophoretic movement to the ground layer 40 having a strong electric field, that is, a relatively strong electric potential. It moves to the region where voltage is applied to the photoconductive layer (⑤).

In addition, the properties of the electrophoresis may vary depending on the type of fluid, the type of microparticles, and the frequency of the AC voltage signal.

For example, if the degree of polarization of the fluid is greater than the degree of polarization of the microparticles, the direction of the dielectrophoretic force acting on the microparticles is formed in the direction opposite to the inclination of the electric field. You move to the weak side. On the contrary, if the degree of polarization of the microparticles is greater than that of the fluid, the dielectrophoretic force is formed in the direction of the inclination of the electric field, and thus the microparticles move toward the strong field.

This degree of polarization is an inherent characteristic of microparticles and fluids and varies depending on the frequency of the AC voltage. Most cells show positive genetic phenomena, and most polymer particles show negative genetic phenomena.

In addition, since the dielectrophoretic force is proportional to the cube of the particle size and the square of the slope of the electric field, the larger the particle is and the larger the electric field is, the stronger the force acts and the faster the movement speed of the fine particles. . In the present invention, by clearly forming a shadow, a distinct virtual electrode may be formed in the photoconductive layer, thereby increasing the electric field slope, thereby making the dielectric force stronger.

In addition, it is also preferable to use the electroosmotic (Electroosmosis) that can be driven by the flow of fluid by the electroosmotic nanoparticles (Nano Particles) small in size due to the relatively low electrophoretic force.

For example, when a voltage is applied to a particular region of the photoconductive layer, the fluid forms the interfacial double layer by the voltage on the photoconductive surface, which is moved by the electric field and flow occurs. The strength of this flow depends on the strength of the electric field, the viscosity of the fluid, and the concentration of the electrolyte, which causes the microparticles to move. In general, the particles are collected by the light irradiated to the photoconductive layer.

6A is a perspective view schematically illustrating a shape in which a pattern is incident on a microparticle driving apparatus using a flat panel display according to the related art, and FIG. 6B is a pattern entering in a microparticle driving apparatus using a flat panel display and a lens according to the present invention. It is a perspective view schematically showing the shape.

As shown in the drawings, the image of the image output to the microparticle drive device 1 using the flat panel display and the lens according to the present invention is formed on the photoconductive layer 30 and the ground layer 40 according to the prior art It appears more clearly than the fine particle driving device using the display, and the amount of incident light also increases by more than 10 times.

Accordingly, the lens 20 may clearly form an image of the flat panel display 1 for driving solid particles in the microfluid by removing dispersion and blur due to diffraction of light.

In addition, the amount of light irradiated from the flat panel display 10 may be transmitted to the photoconductive layer 30 without loss, thereby increasing the voltage change of amorphous silicon inside the phototransistor (not shown) layer in response to the amount of light. Therefore, it is possible to effectively control the solid particles in the microfluid.

In addition, the image pattern irradiated from the flat panel display 10 may be adjusted in size by the magnification of the lens 20, thereby effectively condensing and reducing the solid particles in the microfluid with the reduced image pattern.

7 is a graph showing the microparticle velocity according to the microparticle radius of the microparticle drive device using the flat panel display and the lens and the microparticle drive device of the prior art according to the present invention. As shown in the figure, both the microparticle driving apparatus using the flat panel display and the lens and the microparticle driving apparatus of the prior art increase the driving speed in proportion to the size of the microparticles.

However, the speed according to the fine particle radius is higher when the fine particle driving apparatus using the flat panel display and the lens according to the present invention is used.

Therefore, it is possible to confirm that the driving performance of the fine particles is improved by condensing light by the lens and removing the dispersion of light due to the diffraction phenomenon.

In the microparticle driving apparatus using the flat panel display and the lens according to the present invention, the light emitted from the flat panel display is eliminated by diffraction to form a more distinct and fine virtual electrode in a pattern and area desired by the user. Accordingly, by applying a voltage, it is possible to effectively control the microparticles and the solid particles in the microfluid using one of electroosmosis, electrophoresis, and dielectrophoresis, and to display an image output from a flat panel display. Because of the user's control, it is possible to use the microparticle driving function to selectively move the microparticles and solid particles in the microfluid, and to perform medical, biological and chemical experiments on the chip (Lab-on-a). -chip), miniaturization, low power consumption and throughput can be improved. .

8 is a flow chart schematically showing a method for driving fine particles using a flat panel display and a lens according to the present invention. As shown in the drawing, the method for flowing fine particles using a flat panel display and a lens according to the present invention is performed in a flat panel display. It starts while irradiating light of an arbitrary pattern with a lens (S10).

The lens condenses the light and projects the light onto the photoconductive layer and the ground layer in a desired pattern and area (S20).

In addition, a voltage is applied to light to form a fine virtual electrode in a predetermined region of the photoconductive layer and the ground layer, that is, a pattern and region desired by the user (S30).

In addition, depending on whether the microparticles and the solid particles in the microfluidic are electromagnetically induced by the applied voltage to form an electric dipole (Dipole) is divided into dielectric and electrophoresis (S40). If the particles are charged, they follow electrophoresis, and if they are dielectric materials that induce electric dipoles without charge, they follow the electrophoresis. This also includes the case of electroosmosis in which a flow occurs in the fluid.

In the step S40, when the solid particles in the microfluid are electromagnetically induced by the applied voltage to not form an electric dipole, the microparticles and the solid particles in the microfluid are charged. The electrophoretic and repulsive force causes the solid particles in the microfluid to move in the direction desired by the user (S80).

In the step S40, when the solid particles in the microfluid are electromagnetically induced by the applied voltage to form an electric dipole, the microparticles and the solid particles in the microfluid are not charged. The electrophoresis causes the solid particles in the microfluid to move in the direction desired by the user.

Herein, when the solid particles in the microfluid are moved in a relatively strong electric field direction, the microparticles and the solid particles in the microfluid are moved by positive dielectric motion (S50, S60), on the contrary, in the microparticles and the microfluid. When the solid particles move in a relatively weak electric field, the microparticles and the solid particles in the microfluid are moved due to negative dielectric action (S50 and S70).

Finally, when the microparticles and the solid particles in the microfluid are completed according to the region and pattern desired by the user, the process ends. When the microparticles and the solid particles in the microfluid are not moved according to the region and pattern desired by the user, Go to step S10.

The method of driving fine particles using a flat panel display and a lens according to the present invention removes a phenomenon in which light emitted from a flat panel display is dispersed by diffraction, thereby forming a more distinct and fine virtual electrode in a pattern and an area desired by a user. Accordingly, by applying a voltage, it is possible to effectively control the solid particles in the microfluid using one of electroosmosis, electrophoresis, and dielectrophoresis, and to adjust the image output from the flat panel display. Due to this, it is possible to use the microparticle driving function to selectively move the solid particles in the microfluid, and in the development of a lab-on-a-chip that performs medical, biological and chemical experiments on the chip. , Miniaturization, low power consumption, and increased throughput are possible.

In the above description of the preferred embodiments of the present invention by way of example, the scope of the present invention is not limited only to these specific embodiments and those skilled in the art are appropriate within the scope described in the claims of the present invention. It will be possible to change.

As described above, the present invention having the configuration as described above collects and injects an image irradiated from a flat panel display using a lens, thereby eliminating dispersion phenomenon due to diffraction of light, and thus light incident in an arbitrary pattern. In the photoconductive layer to form a clear and high resolution driving image, thereby moving microparticles inside the microfluid at a desired position, and using a condenser lens having a high numerical aperture and a short focal length, This high, and can be produced such that the production efficiency is high compared to the production cost.

Claims (18)

A flat panel display for illuminating light; A lens for condensing light output from the flat panel display; A photoconductive layer to which a voltage is applied to a region focused by the lens; A ground layer for forming a potential in the photoconductive layer; A microfluidic flow path for moving solid particles in the microfluid at a voltage applied to the focused region of the photoconductive layer; Microparticle drive device using a flat panel display and a lens comprising a. The method of claim 1, The lens is made of a condenser lens for injecting light of any pattern incident from the flat panel display into the photoconductive layer, wherein the focus of any pattern is in an optimal position so as to form the photoconductive layer. Microparticle drive device using a flat panel display and a lens, characterized in that provided. The method of claim 1, The lens is a microparticle drive device using a flat panel display and a lens, characterized in that provided between the flat panel display and the photoconductive layer. The method of claim 1, If the solid particles in the microfluidic charge is a microparticle drive device using a flat panel display and a lens, characterized in that for moving by electrophoresis. The method of claim 1, The microparticle drive device using a flat panel display and a lens, characterized in that when the solid particles in the microfluidics do not carry a charge, it is moved by dielectric action. The method of claim 1, A fine particle driving device using a flat panel display and a lens, characterized in that the dielectric change of the solid particles in the microfluid can be changed by the frequency of the applied alternating voltage. The method of claim 1, The microparticle drive device using a flat panel display and a lens, characterized in that the solid particles in the microfluidic can be moved to the fluid flow by the alternating electrical osmosis (Electroosmosis). The method of claim 1, The flat panel display An intensity pattern forming apparatus capable of forming an arbitrary pattern to irradiate light to apply a voltage to the pattern region with the photoconductive layer and to adjust the contrast of the arbitrary pattern; Microparticle drive device using a flat panel display and a lens comprising a. The method of claim 1, The flat panel display is a fine particle driving apparatus using a flat panel display and a lens, characterized in that to apply one of the LCD or PDP or OLED. The method of claim 1, The photoconductive layer is a microparticle drive device using a flat panel display and a lens, characterized in that the voltage is applied by the photo transistor in the region irradiated with the light output from the flat panel display. The method of claim 1, The voltage applied to the photoconductive layer is a microparticle drive device using a flat panel display and a lens, characterized in that the alternating voltage. The method of claim 1, The photoconductive layer and the ground layer A transparent electrode formed of indium tin oxide (ITO), which is a transparent electrode on a glass substrate; Amorphous silicon deposited on the transparent electrode; Silicon nitride deposited on the amorphous silicon; Microparticle drive device using a flat panel display and a lens comprising a. The method of claim 12, The amorphous silicon is a microparticle driving device using a flat panel display and a lens characterized in that the intrinsic hydrogenated amorphous silicon intrinsic a-Si: H is deposited on the hydrogenated n-type amorphous silicon n + a-Si: H . Condensing light emitted from the flat panel display forming an arbitrary pattern using a lens; Applying a voltage by a phototransistor of a ground layer provided to form a photoconductive layer and a potential in a region to which light refracted and collected by the lens is irradiated; Moving the microparticles or solid particles in the microfluid in a region to which the voltage of the photoconductive layer is applied; Fine particle driving method using a flat panel display and a lens comprising a. The method of claim 14, If the microparticles or solid particles in the microfluidic charges, the microparticle drive method using a flat panel display and a lens, characterized in that for moving by electrophoresis. The method of claim 14, If the microparticles or solid particles in the microfluidic is not charged, the microparticles driving method using a flat panel display and a lens, characterized in that the movement to the electrophoresis. The method of claim 14, A method for driving microparticles using a flat panel display and a lens, characterized in that dielectric change of microparticles or solid particles in a microfluid may be changed at a frequency of an applied alternating voltage. The method of claim 14, The microparticles or the solid particles in the microfluidic can be moved to the fluid flow by the alternating electrical osmosis (Electroosmosis) characterized in that the microparticle drive method using a flat panel display and lens.

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