KR100838104B1 - Device for the promotion of in vitro cell embryo culture - Google Patents

Device for the promotion of in vitro cell embryo culture Download PDF

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KR100838104B1
KR100838104B1 KR1020070075149A KR20070075149A KR100838104B1 KR 100838104 B1 KR100838104 B1 KR 100838104B1 KR 1020070075149 A KR1020070075149 A KR 1020070075149A KR 20070075149 A KR20070075149 A KR 20070075149A KR 100838104 B1 KR100838104 B1 KR 100838104B1
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shelf
groove
hole
rotating body
center
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Korean (ko)
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최선호
한만희
조상래
김현종
최창용
손동수
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대한민국
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/10—Petri dish
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/10—Apparatus for enzymology or microbiology rotatably mounted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/14—Rotation or movement of the cells support, e.g. rotated hollow fibers

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Abstract

A device for promoting development of a cell is provided to make environment similar to the interior body of an animal by moving fertilized eggs contained in a culture dish in all directions using a rotation motor, thereby promoting development of the in vitro cultured fertilized eggs. A device for promoting in vitro cell embryo culture comprises: a motor case(100) and a shelf(D); a rotating body(102) which consists of a motor shaft-inserted opening at a center and a rod groove(104) from the center to the edge direction and is installed on the upper part of the motor case to be rotated by rotation of a motor shaft; a shelf plate(101) having a groove on the center of a lower part of shelf; a body deriving left and right movement of the shelf(103) which consists of a groove bearing(b) inserted into the rod groove of the rotating body, a spherical plane(s1) inserted into an insertion groove of the shelf plate, and a shaft(a) installed at the spherical plane by insertion; and a plurality of shelf holding portions(105) which consists of a pair of brackets(k) and spherical planes(s2) installed at each edges of the motor case and the shelf and a lifting guide(g) connected to a first spherical plane of the pair. Further, the device additionally contains a through hole, an inserting groove, a hook having a fixing hole, and a moving bar installed at the through hole, the hook and a groove bearing.

Description

세포 발달 촉진 기기{Device for the promotion of in vitro cell embryo culture}Device for the promotion of in vitro cell embryo culture

본 발명은 동물의 체내와 유사한 환경을 조성하여 체외 배양되는 수정란을 질적으로 향상시키고, 그의 발달을 촉진시키는 세포 발달 촉진 기기에 관한 것이다.The present invention relates to a cell development promoting device for qualitatively improving the fertilized egg cultured in vitro and promoting its development by creating an environment similar to the body of an animal.

종래는 체외 배양시, 동물 수정란이 담긴 배양 접시를 탄산가스 배양기 내의 고정된 선반 위에 놓고 체외 발달을 유도해 왔으나, 그 수정란이 기형(예: 찌그러진 형상)적으로 발달되거나, 발달율이 저하되는 문제점이 발생되었다. Conventionally, in vitro culture, a culture dish containing animal fertilized eggs was placed on a fixed shelf in a carbon dioxide incubator to induce in vitro development. Occurred.

본 발명은 이러한 문제점을 해결하기 위하여 개발된 것으로, 움직임이 있는 동물의 체내와 유사한 환경을 조성하기 위한 세포 발달 촉진 기기를 제공하는데 그 목적이 있다.The present invention was developed to solve this problem, and an object thereof is to provide a cell development promoting device for creating an environment similar to the body of a moving animal.

상기 목적에 따른 본 발명의 세포 발달 촉진 기기는Cell development promoting device of the present invention according to the above object

선반(즉, 동물 수정란)의 좌우 움직임 발생을 위해, 모터 수용함과 선반, 상기 모터 수용함 상부에 설치된 중심에 모터 축 삽입구와 중심에서 가장자리 방향으로 로드홈이 구성된 회전체, 상기 선반 하부에 접합된 중심에 홈을 가진 선반 받침판, 상기 회전체 로드홈에 삽입된 홈 베어링과 상기 선반 받침판 삽입홈에 삽입된 스페리컬 플레인, 그 홈 베어링과 스페리컬 플레인에 삽입 설치된 중심 축으로 된 선반의 좌우 움직임 유도체, 모터 수용함과 선반의 각 가장자리에 설치된 한 쌍의 브라켓과 스페리컬 플레인, 그 한 쌍의 제1 스페리컬 플레인에 연결된 승강 가이드로 된 다수의 선반 홀딩부를 포함하여 이루어진 것을 특징으로 한다.In order to generate the left and right movement of the shelf (ie, the fertilized egg), a motor housing and a shelf, a rotating body having a motor shaft insertion hole and a rod groove in a center-to-edge direction installed at the center of the motor housing, and joined to the bottom of the shelf Left and right movements of a shelf support plate with a groove in the center, a groove bearing inserted into the rotating rod groove and a spherical plane inserted into the shelf support plate insertion groove, and a center axis inserted into the groove bearing and the spherical plane And a plurality of shelf holding parts comprising a derivative, a motor housing and a pair of brackets and spherical planes installed at each edge of the shelf, and a lifting guide connected to the pair of first spherical planes.

선반의 좌우 움직임 폭 조절을 위해, 상기 회전체 외면 일단부터 로드홈과 접촉하는 부위까지 구성된 관통구, 상기 선반의 좌우 움직임 유도체의 홈 베어링에 구성된 끼움홈, 상기 홈 베어링에 접합되고, 접합시 상기 끼움홈과 대향하는 부위에 걸림구를 가진 훅, 상기 회전체 관통구, 훅 걸림구, 홈 베어링의 끼움홈에 끼움 설치된 이동바를 더 포함하여 이루어진 것을 특징으로 한다.To adjust the left and right movement width of the shelf, a through hole formed from one end of the outer surface of the rotating body to the contact with the rod groove, a fitting groove formed in the groove bearing of the left and right movement derivatives of the shelf, bonded to the groove bearing, It characterized in that it further comprises a hook having a hook on the portion opposite to the fitting groove, the rotating body through hole, hook hooking hole, the mounting bar fitted in the fitting groove of the groove bearing.

선반의 상하 움직임 발생 및 그 폭 조절을 위해, 상기 선반 받침판의 측면에 상호 이격 설치된 다수의 바퀴, 상기 회전체 상부에 안착된 중심에서 가장자리 방향으로 상기 선반 좌우 움직임 유도체의 중심축 이동구를 가진 바퀴받침판, 상기 회전체 가장자리에 구성되고 그 바닥면은 경사면으로 된 수용홈, 상기 회전체 외면 타단부터 상기 수용홈과 접촉하는 부위까지 구성된 제2 관통구, 상기 수용홈에 수용된, 탄성부재가 결합된 선반 상하 움직임의 폭 조절체, 상기 회전체 제2 관통구를 관통 상기 선반 상하 움직임의 폭 조절체를 밀어 주는 푸쉬바를 더 포함하여 이루어진 것을 특징으로 한다.In order to generate the up and down movement of the shelf and to adjust the width thereof, a plurality of wheels spaced apart from each other on the side of the shelf support plate, the wheel having a central axis moving hole of the shelf left and right movement derivatives from the center seated on the top of the rotating body to the edge direction Support plate, the bottom surface is formed on the edge of the rotating body is the receiving groove of the inclined surface, the second through hole configured from the other end of the outer surface of the rotating body to the contact with the receiving groove, the receiving member, the elastic member is coupled Width adjuster of vertical movement of the shelf, push bar for pushing the width of the vertical movement of the shelf through the rotating through the second through hole characterized in that it further comprises.

본 발명은 체외 배양되는 수정란의 발달을 촉진시킬 수 있고, 수정란을 이상형(예:둥근 구 모양)에 가까운 형상이 되게 하여 질적으로 향상시킬 수 있는 효과가 있다. The present invention can promote the development of fertilized eggs to be cultured in vitro, and has the effect of improving the quality by making the fertilized egg into a shape close to an ideal type (for example, round sphere).

이하, 첨부된 도면을 참조하여 본 발명을 설명한다.Hereinafter, with reference to the accompanying drawings will be described the present invention.

① 선반의 좌우 움직임 발생을 위한 구성(참조 도면 : 도 1)① Configuration for generating the left and right movement of the shelf (reference drawing: Fig. 1)

도 1의 본 발명은 선반의 좌우 움직임을 위해, 모터 수용함(100), 선반 받침판(101), 회전체(103), 선반의 좌우 움직임 유도체(104), 다수의 선반 홀딩부(105)가 구성된 것이다. 수정란은 선반(D) 위에 놓여지는 배양 접시에 담긴다.In the present invention of Figure 1 for the left and right movement of the shelf, the motor housing 100, the shelf support plate 101, the rotating body 103, the left and right movement derivatives 104 of the shelf, a plurality of shelf holding portion 105 It is composed. The fertilized egg is placed in a culture dish placed on a shelf (D).

모터 수용함(100)은 플라스틱 재질의 직육면체 구조로 된 것으로 DC 모터, 배터리가 수용된다.The motor housing 100 is a rectangular parallelepiped structure made of plastic and accommodates a DC motor and a battery.

선반 받침판(101)은 원판형이고 하부 중심에 홈이 구성된 것으로, 선반(D) 하면에 접합된다. Shelf base plate 101 is a disk-shaped, the groove is formed in the lower center, is bonded to the bottom surface of the shelf (D).

회전체(102)는 원판형이고 중심에 모터 축 삽입구와 중심에서 가장 자리 방향으로 로드홈(104)이 구성된 것으로 모터 수용함(100) 상부에 설치되어, 모터 축 회전에 따라 회전된다. Rotating body 102 is a disk-shaped and is formed in the center of the motor shaft insertion hole and the center of the rod groove 104 in the direction of the edge is installed on the upper side of the motor housing 100, and rotates in accordance with the rotation of the motor shaft.

선반의 좌우 움직임 유도체(103)는 선반 받침판(101)의 삽입홈에 삽입된 스페리컬 플레인(s1), 회전체(102) 로드홈(104)에 삽입된 홈베어링(b), 그 스페리컬 플레인(s1)과 홈 베어링(b)에 삽입 설치된 중심 축(a)으로 된 것이다. 그 중심 축(a)이 모터 축과 일치하지 않는 로드홈(104) 상에 위치된 경우, 회전체(102) 회전시 선반(D)의 좌우 움직임이 발생된다. The left and right motion derivatives 103 of the lathe are spherical plains s1 inserted into the insertion grooves of the shelf supporting plate 101, groove bearings b inserted into the rod 102 of the rotating body 102, and spherical plains thereof. (s1) and a center shaft (a) inserted into the groove bearing (b). When the central shaft a is located on the rod groove 104 which does not coincide with the motor shaft, the left and right movement of the shelf D occurs when the rotating body 102 is rotated.

다수의 선반 홀딩부(105)는 모터 수용함(100)과 선반(D)의 각 가장자리에 설치된 한 쌍의 브라켓(k)과 스페리컬 플레인(s2), 그 한 쌍의 제1 스페리컬 플레인에 설치된 승강 가이드(g)로 된 것으로, 회전체(102) 회전시 선반(D)을 잡아 회전되지 않고 좌우로 소정 폭만큼 움직이게 한다. 승강 가이드(g)는 결합가능하게 분리되는 구조로 된 것이다.The plurality of shelf holding portions 105 may include a pair of brackets (k) and a spherical plane (s2) installed at each edge of the motor holder (100) and the shelf (D), and a pair of first spherical planes. It is made of the lifting guide (g) provided to hold the shelf (D) at the time of rotation of the rotating body 102 to move to the left and right by a predetermined width without rotating. Lifting guide (g) is of a structure that is separably separated.

②선반의 좌우 움직임 폭 조절을 위한 구성(참조 도면:도 1,2)② Configuration for adjusting the left and right movement width of the shelf (reference drawings: FIGS.

도 1의 본 발명은 선반(D)의 좌우 움직임 폭 조절을 위해 훅(106), 이동바(107), 회전체에 관통구(h1), 선반의 좌우 움직임 유도체의 홈 베어링(b)에 끼움홈이 구성된 것이다.1 of the present invention, the hook 106, the moving bar 107, the through-hole (h1) to the rotating body, the groove bearing (b) of the left and right movement derivative of the shelf for adjusting the left and right movement width of the shelf (D) The groove is configured.

훅(예: 'ㄷ'자형 금속체)(106)은 회전체(102)의 로드홈(104)에 삽입되는 선반의 좌우 움직임 유도체(103)의 홈 베어링(b)에 접합되며, 접합시 그 홈 베어링(b)의 끼움홈과 대향하는 부위에 걸림구(h2)가 구성된 것이다. The hook (eg 'c' shaped metal body) 106 is joined to the groove bearing b of the left and right moving derivative 103 of the lathe inserted into the rod groove 104 of the rotating body 102, A locking hole h2 is formed at a portion of the groove bearing b that faces the fitting groove.

이동바(107)는 회전체(102)의 관통구(h1)를 관통 상기 훅(106)의 걸림구(h2)에 걸리고 상기 선반 좌우 움직임 유도체(103)의 홈 베어링(b) 끼움홈까지 끼움 설치된 것이다.The moving bar 107 is hooked through the through hole h1 of the rotating body 102 to the locking hole h2 of the hook 106 and fits into the groove bearing (b) fitting groove of the shelf left and right movement derivative 103. It is installed.

그래서, 도 2와 같이, 이동바(107)는 사용자 조작에 따라 체결된 선반의 좌우 움직임 유도체(103)를 로드홈(104)을 따라 소정 위치로 이동시키게 된다. 선반(D)의 좌우 움직임 폭은 그 선반 좌우 움직임 유도체(103)의 위치가 회전체(102)의 중심(C)으로부터 멀수록 커지게 된다.Thus, as shown in Figure 2, the movement bar 107 is to move the left and right movement derivative 103 of the shelf fastened in accordance with the user operation to the predetermined position along the rod groove 104. The left and right movement width of the shelf D becomes larger as the position of the shelf left and right movement derivative 103 is farther from the center C of the rotating body 102.

③선반의 상하 움직임 발생 및 그 폭 조절을 위한 구성(참조 도면:도 1,3,4)③ Configuration for the vertical movement of the shelf and its width adjustment (reference drawings: FIGS. 1, 3, 4)

도 1의 본 발명은 선반(D)의 상하 움직임을 위해, 바퀴(w), 바퀴받침판(108), 선반의 상하 움직임 폭 조절체(109), 푸쉬바(110), 회전체(102)에 수용홈(111)과 제2관통구(h3)가 구성된 것이다.1 of the present invention for the vertical movement of the shelf (D), the wheel (w), the wheel support plate 108, the vertical movement width adjusting body 109 of the shelf, push bar 110, the rotating body 102 The receiving groove 111 and the second through hole (h3) is configured.

푸쉬바(110)는 회전체(102)의 제2관통구(h3)를 관통, 회전체(102) 수용홈(111)에 삽입된 선반의 상하 움직임 폭 조절체(106)를 밀어 준다.The push bar 110 penetrates through the second through hole h3 of the rotating body 102 and pushes the vertical movement width adjusting member 106 of the shelf inserted into the receiving body 111 of the rotating body 102.

선반의 상하 움직임 폭 조절체(106)는 탄성부재(예: 용수철)가 결합된 금속체로 된 것으로, 수용홈(111)의 경사진 바닥면을 따라 상기 푸쉬바(110)에 의해 승강된다.The vertical movement width adjusting member 106 of the shelf is made of a metal body to which an elastic member (for example, a spring) is coupled, and is lifted by the push bar 110 along the inclined bottom surface of the receiving groove 111.

바퀴(예: 베어링)(w)는 여러 개가 선반 받침판(101) 측면에 상호 이격되어 설치된다. Wheels (for example, bearings) (w) are installed on the shelf base plate 101 side spaced apart from each other.

바퀴받침판(108)은 원판형으로 중심에 돌출구(h4)와 중심에서 가장자리 방향으로 이동구(h5)가 구성된 것이며, 회전체(102) 상부에 삽입 안착된다. The wheel support plate 108 is a disk-like protrusion (h4) in the center and the moving hole (h5) is configured in the center to the edge direction, and is inserted and seated on the upper portion of the rotating body (102).

그래서, 도 3,4와 같이, 푸쉬바(110)에 의해 밀려진 선반의 상하 움직임 폭 조절체(109)가 수용홈(111)의 경사진 바닥면 상부로 올라가 바퀴받침판(108)을 위로 밀어 돌출되게 하고 하부에서 받쳐 준다. 그래서, 회전체(102) 회전시, 그 위로 돌출된 바퀴받침판(108)과 바퀴(101)가 접촉되어 선반(D)이 기울어져 선반(D)의 상하 움직임이 발생된다. 선반(D)의 상하 움직임 폭은 바퀴받침판(108)이 높이 돌출될수록 커지게 된다.Thus, as shown in FIGS. 3 and 4, the vertical movement width adjusting body 109 of the shelf pushed by the push bar 110 rises to the top of the inclined bottom surface of the receiving groove 111 and pushes the wheel support plate 108 upward. Let it protrude and support from the bottom. Thus, when the rotating body 102 rotates, the wheel support plate 108 and the wheel 101 protruding therefrom are in contact with the shelf D so that the vertical movement of the shelf D occurs. The vertical movement width of the shelf D becomes larger as the wheel support plate 108 protrudes higher.

부가적으로, 상기 바퀴받침판(108)의 돌출구(h4)는 그의 직경이 선반의 좌우 움직임 유도체(103)의 홈 베어링(b) 직경보다 약간 큰 것이고, 이동구(h5)는 그의 직경이 선반의 좌우 움직임 유도체(103)의 중심 축(a) 직경보다 약간 큰 것이다.In addition, the protrusion h4 of the wheel support plate 108 is such that its diameter is slightly larger than the diameter of the groove bearing b of the left and right moving derivative 103 of the shelf, and the movable hole h5 has a diameter thereof of the shelf. It is slightly larger than the diameter of the central axis (a) of the left-right motion derivative (103).

④본 발명의 사용 상태 설명(참조 도면 : 도 5)④ Explanation of the use state of this invention (reference drawing: FIG. 5)

도 5a와 같이 정지된 본 발명은 도 5b와 같이, 선반의 좌우 움직임 유도체(103)가 그의 중심 축(a)이 모터 축과 일치하지 않는 로드홈 상으로 이동되고, 바퀴받침판(108)이 선반의 상하 움직임 폭 조절체(109)에 의해 위로 돌출되고 받쳐진 상태에서 회전체(102)가 회전된 경우, 선반(D) 위에 놓여진 배양 접시(500) 내 의 동물 수정란은 동물의 체내와 유사한 상하, 좌우 움직임을 가질 수 있게 된다. In the present invention, as shown in FIG. 5A, the left and right motion derivatives 103 of the shelf are moved onto a rod groove whose center axis a does not coincide with the motor axis, and the wheel support plate 108 is shelf. When the rotating body 102 is rotated in a state of being projected upward and supported by the vertical movement width adjusting body 109 of the animal, the fertilized egg in the culture dish 500 placed on the shelf D is placed up and down similar to the body of the animal. It will be able to move left and right.

도 1은 본 발명의 세포 발달 촉진 기기의 분해 사시도1 is an exploded perspective view of the cell development promoting device of the present invention

도 2는 도 1의 선반의 좌우 움직임 폭 조절을 위한 실시예의 구성을 보인 부분 결합 사시도Figure 2 is a perspective view of a partially combined showing the configuration of the embodiment for adjusting the left and right movement width of the shelf of Figure 1

도 3은 도 1의 선반의 상하 움직임 발생 및 폭 조절을 위한 실시예의 구성을 보인 부분 결합 사시도Figure 3 is a perspective view of the part combination showing the configuration of the embodiment for the vertical movement generation and width adjustment of the shelf of Figure 1

도 4는 도 1의 선반의 상하 움직임 발생 및 폭 조절을 위한 실시예의 구성을 보인 부분 단면도Figure 4 is a partial cross-sectional view showing the configuration of an embodiment for the vertical movement generation and width adjustment of the shelf of Figure 1

도 5a, 5b는 본 발명의 사용 상태도Figure 5a, 5b is a state diagram of use of the present invention

* 도면의 주요 부분에 대한 부호의 설명 *Explanation of symbols on the main parts of the drawings

100 : 모터 수용함 101 : 선반 받침판100: motor housing 101: shelf support plate

102 : 회전체 103 : 선반의 좌우 움직임 유도체102: rotating body 103: left and right movement derivative of the shelf

104 : 로드홈 105 : 선반 홀딩부104: rod groove 105: shelf holding part

106 : 훅 107 : 이동바106: hook 107: moving bar

108 : 바퀴 받침판 109 : 선반의 상하 움직임 조절체 108: wheel support plate 109: vertical movement control of the shelf

110 : 푸쉬바 111 : 수용홈110: push bar 111: accommodation home

D : 선반 s1, s2 : 스페리컬 플레인D: Shelf s1, s2: Spherical Plain

a : 중심축 b : 홈 베어링a: central axis b: groove bearing

k : 브라켓 w : 바퀴k: bracket w: wheel

h1 : 관통구 h2 : 걸림구h1: through hole h2: locking hole

h3 : 제2 관통구 h4 : 돌출구h3: second through hole h4: protrusion

h5 : 이동구 C : 회전체 중심 h5: moving hole C: center of rotation body

500 : 배양 접시500: Petri Dish

Claims (3)

모터 수용함과 선반;Motor housing and shelves; 상기 모터 수용함 상부에 설치된 중심에 모터 축 삽입구와 중심에서 가장자리 방향으로 로드홈이 구성된 회전체;A rotating body including a motor shaft insertion hole and a rod groove in the center from the center to the center of the motor housing; 상기 선반 하부에 접합된 중심에 홈을 가진 선반 받침판;Shelf support plate having a groove in the center bonded to the lower shelf; 상기 회전체 로드홈에 삽입된 홈 베어링과 상기 선반 받침판 삽입홈에 삽입된 스페리컬 플레인, 그 홈 베어링과 스페리컬 플레인에 삽입 설치된 중심 축으로 된 선반의 좌우 움직임 유도체; 및Left and right movement derivatives of a shelf having a groove bearing inserted into the rotating rod groove and a spherical plain inserted into the shelf support plate inserting groove, and a center axis inserted into the groove bearing and the spherical plain; And 모터 수용함과 선반의 각 가장자리에 설치된 한 쌍의 브라켓과 스페리컬 플레인, 그 한 쌍의 제1 스페리컬 플레인에 연결된 승강 가이드로 된 다수의 선반 홀딩부를 포함하여 이루어진 세포 발달 촉진 기기.A cell development facilitation device comprising a motor holder and a pair of brackets and spherical planes mounted at each edge of the shelf, and a plurality of shelf holding portions of lifting guides connected to the pair of first spherical planes. 제 1 항에 있어서, The method of claim 1, 상기 회전체 외면 일단부터 로드홈과 접촉하는 부위까지 구성된 관통구; A through hole configured from one end of the outer surface to a portion in contact with the rod groove; 상기 선반의 좌우 움직임 유도체의 홈 베어링에 구성된 끼움홈;Fitting grooves formed in the groove bearings of the left and right moving derivatives of the shelf; 상기 홈 베어링에 접합되고, 접합시 상기 끼움홈과 대향하는 부위에 걸림구를 가진 훅; A hook joined to the groove bearing and having a locking hole at a portion facing the fitting groove when joined; 상기 회전체 관통구, 훅 걸림구, 홈 베어링의 끼움홈에 끼움 설치된 이동바를 더 포함하여 이루어진 세포 발달 촉진 기기.Cell rotation promoting device further comprises a moving bar installed in the insertion hole of the rotating body through hole, hook locking hole, groove bearing. 제 1 항에 있어서,The method of claim 1, 상기 선반 받침판의 측면에 상호 이격 설치된 다수의 바퀴;A plurality of wheels spaced apart from each other on the side of the shelf support plate; 상기 회전체 상부에 안착된 중심에서 가장자리 방향으로 상기 선반 좌우 움직임 유도체의 중심축 이동구를 가진 바퀴받침판; A wheel support plate having a central axis moving hole of the shelf left and right movement derivatives from the center seated on the rotating body to the edge direction; 상기 회전체 가장자리에 구성되고 그 바닥면은 경사면으로 된 수용홈;A receiving groove formed at an edge of the rotating body, the bottom surface of which is an inclined surface; 상기 회전체 외면 타단부터 상기 수용홈과 접촉하는 부위까지 구성된 제2 관통구;A second through hole configured from the other end of the outer surface of the rotating body to a portion in contact with the receiving groove; 상기 수용홈에 수용된, 탄성부재가 결합된 선반 상하 움직임의 폭 조절체;Width adjusting body of the vertical movement of the shelf accommodated in the receiving groove, the elastic member is coupled; 상기 회전체 제2 관통구를 관통 상기 선반 상하 움직임의 폭 조절체를 밀어 주는 푸쉬바를 더 포함하여 이루어진 세포 발달 촉진 기기.The cell development promoting device further comprises a push bar for pushing the width adjusting body of the vertical movement of the shelf penetrating the second through-hole of the rotating body.
KR1020070075149A 2007-07-26 2007-07-26 Device for the promotion of in vitro cell embryo culture KR100838104B1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024019195A1 (en) * 2022-07-21 2024-01-25 포항공과대학교 산학협력단 Cell culture device and cell culture system comprising same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01124379A (en) * 1987-11-06 1989-05-17 Shimadzu Corp Culture apparatus
JPH0799962A (en) * 1993-10-06 1995-04-18 Nec Corp Apparatus for arranging and culturing cell and method therefor
KR0129833B1 (en) * 1994-11-09 1998-04-04 박성수 Method of orgna culture and apparatus thereof
KR100431114B1 (en) 2001-10-29 2004-05-12 김정희 A device for shaker the cultivation body in Culture vessel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01124379A (en) * 1987-11-06 1989-05-17 Shimadzu Corp Culture apparatus
JPH0799962A (en) * 1993-10-06 1995-04-18 Nec Corp Apparatus for arranging and culturing cell and method therefor
KR0129833B1 (en) * 1994-11-09 1998-04-04 박성수 Method of orgna culture and apparatus thereof
KR100431114B1 (en) 2001-10-29 2004-05-12 김정희 A device for shaker the cultivation body in Culture vessel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024019195A1 (en) * 2022-07-21 2024-01-25 포항공과대학교 산학협력단 Cell culture device and cell culture system comprising same

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