KR100836861B1 - Feed composition for animal - Google Patents

Abstract

The present invention relates to an animal feed composition, the animal feed composition comprising minerals and nutrients, including Na ₂ O and K ₂ O. The content of Na ₂ O and K ₂ O is Na ₂ O 2 to 6% by weight, K ₂ O 2 to 10% by weight based on the weight of the mineral, Na ₂ O is 0.1 to 3% by weight based on the total animal feed weight, K ₂ O is 0.1 to 3% by weight. The animal feed composition can be used to culture mammals such as chickens, cattle or pigs as well as fish and shellfish such as flounder.

The animal feed composition is a non-specific immune response of the animal without adversely affecting growth and feed efficiency in the domestic aquaculture industry where productivity decreases and diseases frequently occur due to problems such as rapid aquaculture and breeding, and high density breeding. To increase productivity and prevent disease of shellfish wheat animals. In addition, since the feed composition of the present invention has a great effect on boosting immunity, it can be used more effectively as a particulate feed of a young animal. Therefore, the feed composition of the present invention can exhibit a great effect on improving the meat quality and disease resistance of animals such as shellfish and livestock, and can also have a great effect on the water purification action when used in aquaculture.

Animal Feed, Na2O, K2O

Description

Animal feed composition {FEED COMPOSITION FOR ANIMAL}

1 is a graph showing the disease resistance of the flounder cultured by administering the feed of Examples 1 to 3 and Comparative Example 1 of the present invention.

[Industrial use]

The present invention relates to an animal feed composition, and more particularly, to an animal feed composition that maintains cell vitality and regulates an immune enhancing effect by regulating biological growth and physiological function.

[Prior art]

Most of the domestic seafood industry is expanding rapidly. However, productivity problems and the incidence of numerous bacterial, viral and parasitic diseases due to problems such as high density breeding and nutritional imbalances in the production and cultivation of cultured fish and shellfish have become a huge problem, leading to enormous economic losses. It is causing.

In particular, as a countermeasure for aquaculture and shellfish, antibiotics and various types of chemicals are used after disease occurrence, rather than prevention, and the abuse of such drugs causes stress on fish and shellfish to reduce the immune response, as well as to reduce environmental pollution and pathogens. There are many problems such as increased resistance and the possibility of affecting the human body. In Korea, the demand for feed additives that can improve the productivity and prevent disease of farmed fish and shellfish is increasing rapidly by promoting growth and improving feed efficiency, or by enhancing the non-specific immune response and antioxidant capacity of fish and shellfish.

Biostones are being studied as such feed additives. Elvanite is a rock belonging to quartz rock among igneous rocks. It is composed mainly of silicic anhydride and aluminum oxide, and is composed of about 40 kinds of minerals such as ferric oxide, calcium, magnesium, germanium, and selenium which are necessary for human body and living organisms. Bioavailability of the elvan can be divided into three types. First, numerous micropores on the surface and inside of the elvan cause capillary action, which is effective in adsorbing, decomposing and removing harmful substances such as heavy metals such as cadmium and mercury. Second, it activates cells in vivo by releasing far-infrared rays, helping metabolism and blood circulation to facilitate the discharge of waste and harmful substances in the body. Thirdly, the mineral component (about 40 kinds) of elvan is sufficient to supply micronutrients (minerals) which are essential to the living body and are easily deficient, to promote growth, to regulate the growth and physiology of the human body and living organisms, and to maintain normal vitality. It also facilitates various metabolic reactions.

In addition, such feed additives have been actively researched not only for fish and shellfish farming but also for livestock feed such as chicken, cow, and pig.

The present invention is to solve the above problems, an object of the present invention is to provide an animal feed composition excellent in maintaining the cell vitality and excellent immunity enhancing effect by regulating the growth and physiological function.

In order to achieve the above object, the present invention is a mineral containing Na ₂ O and K ₂ O; And a nutrient source, wherein the content of Na ₂ O and K ₂ O provides animal feed compositions of Na ₂ O 2 to 6% by weight and K ₂ O 2 to 10% by weight based on the weight of the mineral.

Hereinafter, the present invention will be described in more detail.

The present invention relates to an animal feed composition, the feed composition comprises Na ₂ O and a mineral containing K ₂ O, Na ₂ content of O and K ₂ O are each 2 to 6% by weight based on the total mineral weight , 2 to 10% by weight is preferred, wherein the total content of Na ₂ O and K ₂ O is more than 4% by weight, preferably 15% by weight or less, and more preferably 6 to 12% by weight. In addition, the content of Na ₂ O is preferably 0.1 to 3% by weight, more preferably 0.2 to 1% by weight, most preferably 0.5% by weight, and K ₂ O based on the total weight of the animal feed composition. To 3% by weight is preferred, more preferably 0.2 to 1.2 and most preferably 0.1 to 0.5% by weight.

Na ₂ O and K ₂ O can impart effects to the animal feed such as disease prevention and treatment, bactericidal action, detoxification in the body, inhibition of the sympathetic nervous system, promotion of growth and increased yield. The minimum content of one of Na ₂ O and K ₂ O may be 2% by weight, but both Na ₂ O and K ₂ O are 2% by weight, and the total content is 4% by weight or less based on the total mineral weight. There is a problem of reduced yield, lower sterilization, lower treatment effect.

In addition, when the content of Na ₂ O exceeds 5% by weight relative to the total mineral weight, there is a problem in excessive sterilization, and when the content of K ₂ O exceeds 10% by weight based on the total mineral weight, There is a problem with the breakdown of balance due to increased yield.

Minerals used in the animal feed of the present invention include kaolin, diatomaceous earth, feldspar, illite or feldspar, which contain Na ₂ O and K ₂ O in an amount in the above-mentioned range and which do not have harmful toxicity to animals. The minerals include SiO ₂ , Al ₂ O ₃ , Fe ₂ O ₃ , CaO, MgO, etc. in addition to Na ₂ O and K ₂ O, and their contents are not important values in the present invention, so they need to be limited. none.

In the animal feed of the present invention, the nutrient source can be appropriately modified according to the type of each animal, which is obviously widely understood in the art. For example, when feeding fish and shellfish farming, the nutrient source may include white fish meal, gelatin, dehulled soybean meal as protein sources, and wheat flour as a carbohydrate source. ) And dextrin, and squid liver oil containing a large amount of polyunsaturated fatty acids may be included as a lipid source. In addition, ascorbic acid, dl-calcium pantothenate, choline bitatrate, inositol, menadione, niacin, pyridoxine / HCl, riboflavin, thiamine Vitamins such as mononitrate, dl-α-tocopherol acetate, retinyl acetate, biotin, folic acid, B _12, etc., NaCl, MgSO ₄ .7H ₂ O, NaH ₂ P ₄ 2H ₂ O, Ca (H ₂ PO ₄ ) ₂ · 2H ₂ O, KH ₂ PO ₄ , ZnSO ₄ · 7H ₂ O, Fe-citrate, Ca-lactate, MnSO ₄ , FeSO ₄ , CuSO ₄ , Calcium Iodate, MgO, NaSeO _3, etc. It may also contain the same minerals.

As used herein, the term "animal" is intended to include both seafood and livestock. The animal feed may be fed when farming seafood such as flounder or when breeding livestock such as pigs, cows, and chickens, but is not limited thereto.

Hereinafter, preferred examples and comparative examples of the present invention are described. However, the following examples are only one preferred embodiment of the present invention and the present invention is not limited to the following examples.

1) Experimental word

Olive flounder was pre-cultured for 2 weeks to adapt to the experimental environment in a 2 ton round tank. After preliminary breeding, the flounder, with an average weight of 5.0 ± 0.04 g (mean ± standard deviation), was randomly placed in three replicates of 25 animals in four 40 L square tanks. Each experimental tank was flow-through, and the flow rate was adjusted to 1 to 2 l / min. Airstone was installed for sufficient oxygen supply and the average water temperature during the experiment period was 17-22 ° C. dependent on the natural water temperature for the entire experiment period. The daily feeding amount was supplied at 4-5% (10 am, 4 pm) of fish weight twice a day during the entire experiment period, and the main breeding experiment was conducted for 8 weeks.

2) experimental feed and experimental design

The composition table of the experimental feed used in the experiment and the general components included in the feed are shown in Table 1. White fish meal, gelatin, and dehulled soybean meal were used as protein sources of the experimental feed.Wheat flour and dextrin were used as carbohydrate sources, and as lipid sources. Squid liver oil containing a large amount of polyunsaturated fatty acid (n-3 HUFA) was used.

Na ₂ O 3.5 wt%, K ₂ O 5.02 wt%, SiO ₂ 73.5 wt%, Al ₂ O ₃ 15.3 wt%, Fe ₂ O ₃ 0.5 wt%, CaO 0.56 wt%, MgO 0.06 wt%, Ignition loss (ignition loss) Minerals containing 1.09% by weight and the remaining trace components were respectively added to 0% by weight (Comparative Example 1), 0.5% by weight (Example 1), 1% by weight (Example 2) and 2% by weight (test Example 3) was added.

Crude protein content of experimental feed was 50.0%, and available energy was 16.7kJ / g (protein, 16.7kJ / g); Lipid, 37.7 kJ / g; Carbohydrates, 16.7 kJ / g) (NRC, 1993). The difference in available energy according to the amount of minerals added to each experimental feed was equally adjusted by adding cellulose. Minerals were prepared and used as fine powder. All experimental feeds were mixed with raw materials and then extruded and molded into a pellet maker, dried with a forced draft dryer (15 ° C. for 24 hours), and then particle size was 500 μm and 1,000 μm standard (sieve). ) And then evenly sealed, and used while being frozen and stored at -20 ° C.

Composition and general analysis of experimental feed (unit: wt% (dry weight basis)) feed Comparative Example 1 Example 1 Example 2 Example 3 White fish meal ¹ (%) 55.0 55.0 55.0 55.0 Gelatin ² (%) 4.5 4.5 4.5 4.5 Peeled Soybean Meal ³ (%) 7.0 7.0 7.0 7.0 Flour ⁴ (%) 14.0 14.0 14.0 14.0 Dextrin ⁵ (%) 5.6 5.6 5.6 5.6 Squid Liver Oil ⁷ (%) 7.9 7.9 7.9 7.9 Vitamin Blend ⁸ (%) 1.0 1.0 1.0 1.0 Mineral Blend ⁹ (%) 3.0 3.0 3.0 3.0 cellulose(%) 2.0 1.5 1.0 0 Mineral ¹⁰ (%) 0 0.5 1.0 2.0 Total composition (%) 100 100 100 100 General membership moisture(%) 20.1 20.4 21.0 21.0 Crude Protein (%) 52.1 52.3 52.1 52.0 Crude fat (%) 13.9 13.9 14.0 14.1 % Viewed 13.9 13.4 12.9 12.9 Total ingredient (%) 100 100 100 100

^{1, 2} strait

³ American Soybean Association

⁴ Youngnam Mills

^{5, 10} United States Biochemical, Cleveland, Ohio, 44122

⁷ Ewha Maintenance

⁸ ingredients, feed content (mg / kg): ascorbic acid, 300; dl-Calcium pantothenate, 150; Choline bitatrate, 3000; Inositol, 150; Menadione, 6; Niacin, 150, pyridoxine HCl, 15; Pyroflavin, 30; Thiamine mononitrate, 15; dl-α-tocopherol acetate, 201; Retinyl acetate, 6; Biotin, 1.5; Folic acid, 5.4; B ₁₂ , 0.06

⁹ ingredients, feed content (mg / kg): NaCl, 437.4; MgSO ₄ 7H ₂ O, 1379.8; NaH ₂ P ₄ 2H ₂ O, 877.8; Ca (H ₂ PO ₄ ) ₂ .2H ₂ O, 1366.7, KH ₂ PO ₄ , 2414; ZnSO ₄ 7H ₂ O, 226.4; Fe-citrate, 299; Ca-lactate, 3004; MnSO ₄ , 0.016; FeSO ₄ , 0.0378; CuSO ₄ , 0.00033; Calcium iodate, 0.0006; MgO, 0.00135; NaSeO ₃ , 0.00025

* Statistics processing

Statistical processing of all data was carried out by ANOVA test with the computer program Statisix 3.1 (Analytical Software, St. Paul MN. USA) and Least Significant Difference (LSD). (P <0.05) was assayed.

3) Experiment result

① Attack experiment

A. Materials and Methods

Toxic Edwardsiella tarda suspension (1 × 10 ⁶ cfu / ml) was incubated for 48 hours at 27 ° C. in trypticase soy agar (TSA) containing 1.5% NaCl. Ready. Death was recorded after intraperitoneal injection of 0.1 ml bacterial suspension per fish. To confirm the cause of mortality, kidneys were collected from the dead fish bodies and cultured in TSA to confirm the presence of E. tarda.

B. Results

After intraperitoneal injection with E. tarda FPC 799 strain, the cumulative survival rate of each experimental group was examined and the results are shown in FIG. 1 (P <0.05). As shown in FIG. 1, it can be seen that Examples 2 to 3 have a higher cumulative survival rate than Comparative Example 1. The mortality began to appear on day 4 after intraperitoneal injection, mortality spiked around 9-10 days, and no mortality occurred after 13 days. This means that Example 1, in which the mineral of the present invention was added, was further enhanced in disease resistance (disease resistance) when compared with Comparative Example 1. In addition, according to this result, it can be predicted that the mineral of the present invention promotes the health of fish by releasing far-infrared rays, activating cells in vivo, and helping metabolism and blood circulation to facilitate the discharge of waste harmful substances in the body. have.

Animal feed composition comprising Na ₂ O and K ₂ O of the present invention in a specific content has been applied to the domestic aquaculture industry, where productivity decreases and diseases frequently occur due to problems such as high density breeding with rapid expansion of aquaculture and breeding. Enhancement of nonspecific immune responses in animals without adversely affecting growth and feed efficiency can improve productivity and prevent disease in shellfish wheat animals. In addition, since the feed composition of the present invention has a great effect on boosting immunity, it can be used more effectively as a particulate feed of a young animal. Therefore, the feed composition of the present invention can exhibit a great effect on improving the meat quality and disease resistance of animals such as shellfish and livestock, and can also have a great effect on the water purification action when used in aquaculture.

Claims (5)

Mineral additives including Na ₂ O and K ₂ O; And Includes nutritional sources, The content of Na ₂ O and K ₂ O is Na ₂ O 2 to 6% by weight, K ₂ O 2 to 10% by weight based on the total weight of the mineral additive (where the total amount of Na ₂ O and K ₂ O is a mineral additive 6 to 12% by weight relative to the total weight), The mineral additive is contained in 0.5 to 1% by weight based on the total weight of the animal feed composition, The nutrient source is a protein source selected from the group consisting of white fish meal, gelatin and dehulled soybean meal; Carbohydrate source selected from the group consisting of wheat flour and dextrin; Lipid sources including squid liver oil containing a large amount of polyunsaturated fatty acids; Ascorbic acid, dl-calcium pantothenate, choline bitatrate, inositol, menadione, menadione, niacin, pyridoxineHCl, riboflavin, thiamine mononitrate Vitamins selected from the group consisting of latex, dl-α-tocopherol acetate, retinyl acetate, biotin, folic acid, and B ₁₂ ; NaCl, MgSO ₄ 7H ₂ O, NaH ₂ P ₄ 2H ₂ O, Ca (H ₂ PO ₄ ) ₂ 2H ₂ O, KH ₂ PO ₄ , ZnSO ₄ 7H ₂ O, Fe-citrate, Ca- An animal feed composition comprising a mineral selected from the group consisting of lactate, MnSO ₄ , FeSO ₄ , CuSO ₄ , calcium iodate, MgO, and NaSeO ₃ . delete delete delete The animal feed composition of claim 1, wherein the nutrient source is a nutrient source supplied to a mammal or a shellfish.

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