KR100792658B1 - Device for dissolving thrombus in blood vessel by magnetostrictive vibrator - Google Patents

Device for dissolving thrombus in blood vessel by magnetostrictive vibrator Download PDF

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KR100792658B1
KR100792658B1 KR1020060067204A KR20060067204A KR100792658B1 KR 100792658 B1 KR100792658 B1 KR 100792658B1 KR 1020060067204 A KR1020060067204 A KR 1020060067204A KR 20060067204 A KR20060067204 A KR 20060067204A KR 100792658 B1 KR100792658 B1 KR 100792658B1
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magnetostrictive vibrator
magnetic field
magnetostrictive
generating mechanism
alternating magnetic
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Korean (ko)
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성 현 김
성 권 강
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주식회사 에스앤지바이오텍
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/08Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
    • A61B18/082Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345Vascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0218Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement
    • A61H2023/0227Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement with magnetostrictive elements

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Abstract

A device for dissolving thrombus in blood vessels using a magnetostrictive vibrator is provided to effectively and safely treat diseases caused by a vascular occlusion such as an ischaemic stroke by the use of an ultrasonic resonance generated by an external magnetic field. A device for dissolving thrombus in blood vessels using a magnetostrictive vibrator(1) includes the magnetostrictive vibrator, a guide wire pusher(2), an alternating current magnetic field generating mechanism(3), and a vibration generator(4). The magnetostrictive vibrator is formed by fitting cylindrical bars(1a) made of magnetostrictive materials into wires(1c). The guide wire pusher extends at one side of the magnetostrictive vibrator. The alternating current generating mechanism generates an alternating current magnetic field outside a human body to transfer the alternating current magnetic field to the magnetostrictive vibrator. The vibration generator transmits a vibration signal to the alternating current generating mechanism. The alternating current generating mechanism is an electromagnet.

Description

자왜진동자를 이용한 혈관내 혈전 용해 기구 {Device for dissolving thrombus in blood vessel by magnetostrictive vibrator}Device for dissolving thrombus in blood vessel by magnetostrictive vibrator

도 1은 본 발명에 따른 혈관내 혈전 용해 기구의 모식도.1 is a schematic diagram of the vascular thrombolytic mechanism according to the present invention.

도 2는 본 발명을 구성하는 자왜진동자(1) 일례의 단면 개략도.2 is a schematic cross-sectional view of an example of a magnetostrictive vibrator 1 constituting the present invention.

도 3은 본 발명을 구성하는 교류 자장 발생기구(3)의 사용형태 일례를 나타내는 사진.Fig. 3 is a photograph showing an example of the use mode of the alternating magnetic field generating mechanism 3 constituting the present invention.

*도면중 주요 부분에 대한 부호 설명* Description of symbols on the main parts of the drawings

1: 자왜진동자 2: 가이드 와이어 푸셔1: magnetostrictive oscillator 2: guide wire pusher

3: 교류 자장 발생기구 4: 진동발생기3: AC magnetic field generating mechanism 4: Vibration generator

1a : 자왜물질의 원통형 막대 1b : 구상 자석 1c : 와이어1a: cylindrical rod of magnetostrictive material 1b: spherical magnet 1c: wire

본 발명은 자왜진동자를 이용한 혈관내 혈전 용해 기구에 관한 것으로서, 보다 구체적으로는 인체 외부에 위치하는 교류 자장 발생기구에서 발생되는 외부 교류자장을 전달받아 자왜진동자가 생성하는 초음파를 이용한 혈관내 혈전 용해 기구 에 관한 것이다.The present invention relates to an intravascular blood clot dissolving mechanism using a magnetostrictive vibrator, and more specifically, to an intravascular blood clot dissolving method using an ultrasonic wave generated by the magnetostrictive vibrator by receiving an external alternating magnetic field generated by an alternating magnetic field generating mechanism located outside the human body. It is about an appliance.

최근, 대표적인 혈관질환인 뇌혈관 질환은 단일 질환 사망원인 1위에 해당될 만큼 치료가 어려운 질환으로 대두되고 있다.Recently, cerebrovascular disease, which is a representative vascular disease, has emerged as a disease that is difficult to treat as it corresponds to the number one cause of death of a single disease.

뇌혈관 질환 중에서도 뇌동맥이 혈전에 의해 막혀 발생되는 허혈성 뇌졸중은 현재 완치율이 25∼30%에 불과하며, 치명율이 약 25%에 달하고, 치료 후 반신불수, 실어증 등의 장애가 남는 비율이 50% 이상으로 높아 각 가정의 부담은 물론 심각한 사회적 부담이 되고 있다.Among the cerebrovascular diseases, ischemic strokes caused by clots of the cerebral arteries are currently at cure rate of 25-30%, fatality rate is about 25%, and more than 50% of patients with dysentery and aphasia remain after treatment. As a result, the burden on each family is, of course, a serious social burden.

그럼에도 불구하고, 현재까지는 허혈성 뇌졸중을 효과적으로 치료하는 기구가 개발되지 않은 실정이다.Nevertheless, to date, no mechanism for effectively treating ischemic stroke has been developed.

지금까지는 뇌동맥을 막고 있는 혈전을 제거해 주기 위해서 동맥내 또는 정맥내에 혈전용해제를 투여하는 방법이 주로 사용되고 있다.Until now, the method of administering thrombolytics to arteries or veins has been mainly used to remove clots that are blocking the cerebral arteries.

그러나 동맥 또는 정맥 내에 혈전용해제를 투여하는 방법의 경우에는 완치율이 약 30% 수준으로 낮고, 뇌 내 출혈이 발생할 확률이 10배 정도 높아지는 문제점이 있었다.However, in the case of administering thrombolytics in arteries or veins, there is a problem that the cure rate is low to about 30%, and the probability of bleeding in the brain increases by about 10 times.

한편, 심근경색 질환의 치료시 에는 초음파 발생기를 관상동맥에 삽입하여 초음파를 이용하여 관상동맥을 막고 있는 혈전을 용해하는 방법이 이미 사용되어 왔다.Meanwhile, in the treatment of myocardial infarction disease, a method of dissolving a blood clot blocking the coronary artery has been already used by inserting an ultrasonic generator into the coronary artery.

그러나, 심근경색의 치료에 사용되는 초음파 이용 치료기구는 직경이 3mm 이상으로 크고 유연성이 높지 않아 평균 굵기가 2∼3mm이고 그 도달경로의 굴곡이 심한 뇌동맥 내로 삽입이 불가능하여 허혈성 뇌졸중 치료에는 적용될 수 없었다.However, the ultrasound-applied therapeutic apparatus used for the treatment of myocardial infarction is more than 3mm in diameter and not very flexible, so the average thickness is 2-3mm and it is impossible to be inserted into the cerebral artery with its curved path. There was no.

본 발명의 목적은 이와 같은 종래의 문제점들을 해결할 수 있도록 외부 자장에 의해 발생되는 자왜진동자를 이용한 혈관내 혈전 용해 기구를 제공하기 위한 것이다.An object of the present invention is to provide an intravascular thrombi lysis apparatus using a magnetostrictive oscillator generated by an external magnetic field to solve such conventional problems.

본 발명은 가는 뇌동맥 내에도 삽입이 가능하도록 자왜진동자(1)의 직경을 2mm 이하로 하기 위해서 교류 자장을 발생시키는 교류 자장 발생기구(3)를 수술시 인체 외부에 위치하도록 자왜진동자(1)와 분리한 후 외부 자장에 의해 발생되는 초음파를 이용하여 혈관내의 혈전을 용해시키는 기구를 제공하고자 한다.According to the present invention, the magnetostrictive vibrator 1 and the magnetostrictive vibrator 1 for generating an alternating magnetic field generator 3 for generating an alternating magnetic field so as to be inserted into the narrow cerebral artery are located outside the human body during surgery. The present invention provides a mechanism for dissolving blood clots in blood vessels by using ultrasonic waves generated by an external magnetic field after separation.

또한, 본 발명은 초음파가 효과적으로 발생할 수 있도록 혈관 속에 삽입되는 자왜진동자(1)가 자왜물질로 이루어진 원통형 막대들이 와이어에 끼워져 있는 형태인 자왜진동자를 이용한 혈관내 혈전 용해 기구를 제공하고자 한다.In addition, the present invention is to provide an intravascular thrombi lysis apparatus using a magnetostrictive vibrator in which a cylindrical rod made of magnetostrictive material is inserted into a wire so that the magnetostrictive vibrator 1 inserted into a blood vessel can effectively generate ultrasonic waves.

이와 같은 과제들을 달성하기 위한 본 발명의 자왜진동자를 이용한 혈관내 혈전 용해 기구는, 자왜물질로 이루어진 원통형 막대(1a)들이 와이어(1c)에 끼워져 있는 형태인 자왜진동자(1), 상기 자왜진동자(1)의 일측에 연장되어 있는 가이드 와이어 퓨셔(2), 이들과 별도로 분리되어 인체외부에서 교류 자장을 발생시켜 상기 자왜진동자에 전달해 주는 교류 자장 발생기구(3) 및 상기 교류 자장 발생기구(3)에 진동 신호를 보내 주는 진동발생기(4)로 구성됨을 특징으로 한다.The vascular thrombolysis device using the magnetostrictive vibrator of the present invention for achieving the above object is a magnetostrictive vibrator (1), the magnetostrictive vibrator (shaped) in which the cylindrical rod (1a) made of magnetostrictive material is fitted to the wire (1c) A guide wire pusher (2) extending on one side of 1), an alternating magnetic field generating mechanism (3) and the alternating magnetic field generating mechanism (3) which are separated from these and generate an alternating magnetic field outside the human body and transmit the alternating magnetic field to the magnetostrictive vibrator. It is characterized by consisting of a vibration generator (4) for sending a vibration signal to.

이하, 첨부한 도면 등을 통하여 본 발명을 상세하게 설명한다.Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

먼저, 본 발명은 도 1과 같이 자왜진동자(1), 가이드와이어 푸셔(2),이들과 별도로 분리되어 인체외부에서 교류 자장을 발생시켜 상기 자왜진동자에 전달해 주는 교류 자장 발생기구(3) 및 상기 교류 발생 기구에 진동 신호를 보내 주는 진동발생기(4)로 구성되어 외부 자장에 의해 발생되는 초음파를 이용하여 혈관내 혈전을 용해시킨다.First, the present invention, as shown in Figure 1 magnetostrictive vibrator (1), guide wire pusher (2), separated from these, alternating magnetic field generating mechanism (3) for generating an alternating magnetic field outside the human body and transmitting to the magnetostrictive vibrator and the It is composed of a vibration generator (4) for sending a vibration signal to the alternating current generation mechanism to dissolve the blood clots in the blood vessel using ultrasonic waves generated by an external magnetic field.

도 1은 본 발명에 따른 자왜진동자를 이용한 혈관내 혈전 용해 기구의 모식도이다.1 is a schematic diagram of an intravascular thrombi lysis apparatus using a magnetostrictive vibrator according to the present invention.

상기의 자왜진동자(1)는 도 2에 도시된 바와 같이 자왜물질로 만들어진 작은 원통형 막대(1a)가 연속적으로 와이어(1c)에 의해 조립되어 있는 구조를 갖는다.The magnetostrictive vibrator 1 has a structure in which a small cylindrical rod 1a made of magnetostrictive material is continuously assembled by the wire 1c, as shown in FIG.

구체적으로, 자왜진동자(1)는 자왜물질로 만들어진 원통형 막대(1a)의 가운데 뚫린 구멍으로 와이어(1c)를 통과시켜 여러개의 원통형 막대들이 와이어에 조립끼워져 있는 구조이다.Specifically, the magnetostrictive vibrator 1 has a structure in which a plurality of cylindrical rods are assembled to the wire by passing the wire 1c through a hole drilled in the center of the cylindrical rod 1a made of magnetostrictive material.

자왜물질로 이루어진 원통형 막대(1a) 각각의 길이가 길어질수록 자왜 효과에 의한 변위가 커지지만 긴 막대형태의 자왜진동자는 굴곡이 심한 혈관내에는 삽입할 수 없기 때문에 본 발명에서는 짧은 막대형태의 자왜물질 여러개를 와이어에 끼워 조립함으로써 충분한 자왜막대의 길이를 얻고 동시에 혈관내에 삽입할 수 있도록 유연성을 부여한다. As the length of each of the cylindrical rods 1a made of magnetostrictive material increases, the displacement due to the magnetostrictive effect increases. However, the long rod-shaped magnetostrictive vibrator cannot be inserted into a blood vessel with a high curvature. Assembling several pieces of wires together gives sufficient magnetostrictive bar length and flexibility in inserting them into blood vessels at the same time.

자왜진동자(1)의 직경은 뇌동맥 내에 삽입이 가능하도록 2mm 이하인 것이 바람직하다. 상기 직경이 2mm를 초과하는 경우에는 뇌동맥 내에 자왜진동자(1)의 삽 입이 어렵게 된다.The diameter of the magnetostrictive vibrator 1 is preferably 2 mm or less to allow insertion into the cerebral artery. If the diameter exceeds 2mm, it is difficult to insert the magnetostrictive vibrator 1 into the cerebral artery.

한편, 자왜진동자(1)는 자왜물질로 만들어진 짧은 막대(1a)와 짧은 막대형태 또는 구(球)형태의 자석을 교대로 와이어(1c)에 끼워 조립하여 자왜현상의 효율성을 높이는 자기 바이어스를 부여할 수 있다.On the other hand, the magnetostrictive vibrator 1 alternately assembles a short rod 1a made of a magnetostrictive material and a magnet in the form of a short rod or a sphere into the wire 1c to impart a magnetic bias to increase the efficiency of magnetostriction. can do.

또한 자왜물질로 만들어진 원통형 막대(1a)의 가운데 형성되어 있는 구멍을 통하여 와이어(1c)를 통과시켜 조립하는 과정에 와이어(1c)의 장력을 이용하여 자왜 막대에 자왜 현상의 효율성을 높이는 외부 응력을 인가할 수 있다.In addition, by using the tension of the wire (1c) in the process of assembling the wire (1c) through the hole formed in the center of the cylindrical rod (1a) made of magnetostrictive material to the external stress to increase the efficiency of the magnetostrictive phenomenon in the magnetostrictive rod Can be authorized.

다음으로, 가이드와이어 푸셔(2)는 자왜진동자(1)를 혈관내에 삽입 하는 지지대 역할을 동시에 수행한다.Next, the guide wire pusher 2 simultaneously serves as a support for inserting the magnetostrictive vibrator 1 into the blood vessel.

다음으로, 교류 자장 발생기구(3)는 교류 전원을 인가 받아 교류 자기장을 자왜진동자(1)에 인가하여 자왜효과에 의한 자왜진동자의 진동을 만들어 내는 역할을 하는 솔레노이드 코일 또는 전자석이고, 이들은 자석밀도가 0.1∼1T 수준인 것이 바람직하다.Next, the AC magnetic field generating mechanism 3 is a solenoid coil or an electromagnet which acts to generate the vibration of the magnetostrictive vibrator due to the magnetostrictive effect by applying the AC power to the magnetostrictive vibrator 1 by applying an AC power source, and these are magnet densities. Is preferably 0.1 to 1T.

다음으로, 진동발생기(4)는 교류 자장 발생기구(3)에 진동신호를 보내는 역할을 하며, RF 발생기 또는 소리 발생기(Audio Generator)등 이다.Next, the vibration generator 4 serves to send a vibration signal to the AC magnetic field generating mechanism (3), and is an RF generator or a sound generator.

도 3은 교류 자장 발생기구(3)의 사용 형태 중 일례를 나타내는 사진이다. 3 is a photograph showing an example of a use form of the alternating magnetic field generating mechanism 3.

상기의 교류 자장 발생기구(3)은 혈관내 혈전용해시 환자 인체의 외부에 위치하고 높은 자석밀도를 갖기 때문에 교류 자장 발생기구(3) 주변의 금속체를 잡아당겨 수술 환경이 위험하게 될 수 있다.Since the alternating magnetic field generating mechanism 3 is located outside the patient's body during vascular thrombolysis and has a high magnetic density, the surgical environment may be dangerous by pulling a metal body around the alternating magnetic field generating mechanism 3.

따라서, 도 3과 같이 교류 자장 발생기구(3)를 보호 커버로 감싸주는 것이 바람직하다.Therefore, it is preferable to surround the AC magnetic field generating mechanism 3 with a protective cover as shown in FIG. 3.

본 발명을 구성하는 자왜진동자(1)와 가이드와이어 푸셔(2)는 일체로 연결되어 있으며, 교류 자장 발생기구(3)와 진동발생기(4)는 이들과 분리되어 체외에 있다.The magnetostrictive vibrator 1 and the guide wire pusher 2 constituting the present invention are integrally connected, and the alternating magnetic field generating mechanism 3 and the vibration generator 4 are separated from them and are in vitro.

혈관내 혈전용해 치료시 자왜진동자(1)는 혈관 내에 혈전이 있는 부분까지 삽입되며 교류 자장 발생기구(3)는 인체의 외부, 보다 구체적으로는 자왜진동자가 삽입된 인체 주변에 위치하면서 외부 자장을 발생시켜 이를 자왜진동자(1)에 전달하게 된다.During intravascular thrombolysis treatment, the magnetostrictive vibrator 1 is inserted into the blood clot in the blood vessel, and the alternating magnetic field generating mechanism 3 is located outside the human body, more specifically, around the human body in which the magnetostrictive vibrator is inserted. It is generated and delivered to the magnetostrictive vibrator (1).

혈관내에 삽입된 자왜진동자(1)는 교류 자장 발생기구(3)에서 보내주는 외부자장에 의해 초음파를 발생시켜 혈관을 막고 있는 혈전을 용해하게 된다.The magnetostrictive vibrator 1 inserted into the blood vessel generates ultrasonic waves by an external magnetic field sent from the alternating magnetic field generating mechanism 3 to dissolve the blood clots blocking the blood vessel.

본 발명은 혈관 내에 자왜진동자를 삽입한 후 외부 자장에 의해 발생되는 초음파 공진을 이용하여 혈관내의 혈전을 용해시키기 때문에 허혈성 뇌졸중 등과 같이 혈관폐색에 의한 질환을 효과적이고도 안전하게 치료하는 것이 가능하다.The present invention dissolves blood clots in blood vessels by using ultrasonic resonance generated by an external magnetic field after inserting a magnetostrictive vibrator into blood vessels, thereby effectively and safely treating diseases caused by vascular occlusion, such as ischemic stroke.

또한, 본 발명에서는 외부 자장을 일으키는 교류 자장 발생기구가 자왜진동자와 분리되기 때문에 자왜진동자의 직경을 최소화할 수 있어서 상기 자왜진동자를 직경이 2∼3mm로 작고 도달경로의 굴곡이 심한 뇌동맥 안으로도 삽입하기 용이하며, 자왜진동자에 전원이 인가되지 않기 때문에 열이 나지 않으며 전류나 열에 의한 혈관 손상의 염려가 없다.In addition, in the present invention, since the alternating magnetic field generating mechanism causing the external magnetic field is separated from the magnetostrictive vibrator, the diameter of the magnetostrictive vibrator can be minimized, so that the magnetostrictive vibrator is also inserted into the cerebral artery having a small diameter of 2 to 3 mm and having a large bend of the arrival path. It is easy to do it, and since no power is applied to the magnetostrictive vibrator, it does not generate heat and there is no fear of blood vessel damage caused by current or heat.

Claims (6)

자왜물질로 이루어진 원통형 막대(1a)들이 와이어(1c)에 끼워져 있는 형태인 자왜진동자(1), 상기 자왜진동자(1)의 일측에 연장되어 있는 가이드 와이어 퓨셔(2), 이들과 별도로 분리되어 인체외부에서 교류 자장을 발생시켜 상기 자왜진동자에 전달해 주는 교류 자장 발생기구(3) 및 상기 교류 자장 발생기구(3)에 진동 신호를 보내 주는 진동발생기(4)로 구성됨을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The magnetostrictive vibrator 1 in which cylindrical rods 1a made of magnetostrictive material are fitted to the wire 1c, a guide wire pusher 2 extending to one side of the magnetostrictive vibrator 1, and are separated from the human body Using a magnetostrictive vibrator, characterized in that it consists of an alternating magnetic field generating mechanism (3) for generating an alternating magnetic field from the outside and transmitting it to the magnetostrictive vibrator and a vibration generator (4) for transmitting a vibration signal to the alternating magnetic field generating mechanism (3). Vascular thrombolytic mechanism. 제1항에 있어서, 상기의 교류 자장 발생기구(3)가 전자석인 것을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The vascular thrombolysis device using a magnetostrictive vibrator according to claim 1, wherein the alternating magnetic field generating mechanism (3) is an electromagnet. 제1항에 있어서, 상기의 교류 자장 발생기구(3)가 솔레노이드 코일인 것을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The vascular thrombolysis device using a magnetostrictive vibrator according to claim 1, wherein said alternating magnetic field generating mechanism (3) is a solenoid coil. 제1항에 있어서, 상기의 교류 자장 발생기(3) 및 진동발생기(4)는 상기의 자왜진동자(1) 및 가이드 와이어 푸셔(2)와 분리되어 인체 외부에 위치하는 것을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The magnetostrictive vibrator according to claim 1, wherein the alternating magnetic field generator (3) and the vibration generator (4) are located outside the human body separately from the magnetostrictive vibrator (1) and the guide wire pusher (2). Intravascular thrombi lysis apparatus. 제1항에 있어서, 상기의 자왜진동자(1)는 자왜물질로 이루어진 원통형 막대(1a)들과 구상 또는 원통형 막대 자석(1b)들이 교대로 와이어에 끼워져 있는 형태인 것을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The magnetostrictive vibrator according to claim 1, wherein the magnetostrictive vibrator 1 has a shape in which cylindrical rods 1a made of magnetostrictive material and spherical or cylindrical rod magnets 1b are alternately fitted to a wire. Vascular thrombolytic mechanism. 제2항 또는 제3항에 있어서, 상기의 전자석 및 솔레노이드 코일은 자석밀도가 0.1∼1.0T인 것을 특징으로 하는 자왜진동자를 이용한 혈관내 혈전 용해 기구.The vascular thrombolysis mechanism using a magnetostrictive vibrator according to claim 2 or 3, wherein the electromagnet and the solenoid coil have a magnet density of 0.1 to 1.0T.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003030751A1 (en) 2001-10-05 2003-04-17 Omnisonics Medical Technologies, Inc. Method and apparatus for removing plaque from blood vessels using ultrasonic energy
KR20030036137A (en) * 2000-02-09 2003-05-09 스펜서 테크놀러지스 인크 Method and apparatus combining diagnostic ultrasound with therapeutic ultrasound to enhance thrombolysis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030036137A (en) * 2000-02-09 2003-05-09 스펜서 테크놀러지스 인크 Method and apparatus combining diagnostic ultrasound with therapeutic ultrasound to enhance thrombolysis
WO2003030751A1 (en) 2001-10-05 2003-04-17 Omnisonics Medical Technologies, Inc. Method and apparatus for removing plaque from blood vessels using ultrasonic energy

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