KR100604218B1 - 안티센스 올리고뉴클레오티드에 의한 사람의유두종바이러스의 억제 - Google Patents
안티센스 올리고뉴클레오티드에 의한 사람의유두종바이러스의 억제 Download PDFInfo
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- KR100604218B1 KR100604218B1 KR1020007002392A KR20007002392A KR100604218B1 KR 100604218 B1 KR100604218 B1 KR 100604218B1 KR 1020007002392 A KR1020007002392 A KR 1020007002392A KR 20007002392 A KR20007002392 A KR 20007002392A KR 100604218 B1 KR100604218 B1 KR 100604218B1
- Authority
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- South Korea
- Prior art keywords
- antisense
- cells
- delete delete
- seq
- oligonucleotides
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- Expired - Fee Related
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/312—Phosphonates
- C12N2310/3125—Methylphosphonates
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/34—Spatial arrangement of the modifications
- C12N2310/346—Spatial arrangement of the modifications having a combination of backbone and sugar modifications
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/929,140 US6084090A (en) | 1997-09-05 | 1997-09-05 | Human papilloma virus anti-sense oligonucleotides |
| US08/929,140 | 1997-09-05 | ||
| PCT/US1998/018320 WO1999013071A1 (en) | 1997-09-05 | 1998-09-03 | Human papilloma virus inhibition by anti-sense oligonucleotides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20010015573A KR20010015573A (ko) | 2001-02-26 |
| KR100604218B1 true KR100604218B1 (ko) | 2006-07-25 |
Family
ID=25457385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007002392A Expired - Fee Related KR100604218B1 (ko) | 1997-09-05 | 1998-09-03 | 안티센스 올리고뉴클레오티드에 의한 사람의유두종바이러스의 억제 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US6084090A (https=) |
| EP (2) | EP1595954A1 (https=) |
| JP (1) | JP2002509692A (https=) |
| KR (1) | KR100604218B1 (https=) |
| AU (1) | AU9218398A (https=) |
| CA (1) | CA2302148A1 (https=) |
| WO (1) | WO1999013071A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000061804A1 (en) * | 1999-04-14 | 2000-10-19 | Musc Foundation For Research Development | Tissue-specific and pathogen-specific toxic agents and ribozymes |
| EP1353935A4 (en) * | 2000-12-07 | 2005-02-23 | Penn State Res Found | SELECTION OF TARGET CATALYTIC NUCLEIC ACIDS ON INFECTIOUS AGENTS |
| DE10154831A1 (de) * | 2001-11-08 | 2003-06-05 | Deutsches Krebsforsch | PNA-Konjugat oder PNA-Konjugat-Gemisch zur Therapie von mit HPV in Zusammenhang stehenden Erkrankungen |
| US7704965B2 (en) * | 2002-06-26 | 2010-04-27 | The Penn State Research Foundation | Methods and materials for treating human papillomavirus infections |
| US20040248085A1 (en) * | 2002-11-29 | 2004-12-09 | Sang-Wha Lee | General primers and process for detecting diverse genotypes of human papillomavirus by PCR |
| GB0500999D0 (en) * | 2005-01-18 | 2005-02-23 | Glaxosmithkline Biolog Sa | Detection method and materials therefor |
| KR101197627B1 (ko) | 2010-01-18 | 2012-11-07 | (주)레퍼런스바이오랩 | Hpv 감염과 관련된 암의 치료용 조성물 |
| KR102129852B1 (ko) * | 2016-10-11 | 2020-07-24 | 주식회사 인코드젠 | Rna 간섭 유도 핵산 및 이를 포함하는 hpv 감염 유발 암의 치료용 약학 조성물 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993020095A1 (en) * | 1992-03-31 | 1993-10-14 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide inhibition of papillomavirus |
| WO1995031552A2 (en) * | 1994-05-13 | 1995-11-23 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Human papilloma virus inhibition by a hairpin ribozyme |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU687492B2 (en) * | 1993-11-16 | 1998-02-26 | Genta Incorporated | Synthetic oligomers having phosphonate internucleosidyl linkages of undefined chirality mixed with non-phosphonate internucleosidyl linkages |
| US5580967A (en) * | 1994-05-13 | 1996-12-03 | The Scripps Research Institute | Optimized catalytic DNA-cleaving ribozymes |
| US6509149B2 (en) * | 1995-06-06 | 2003-01-21 | Hybridon, Inc. | HPV-specific oligonucleotides |
-
1997
- 1997-09-05 US US08/929,140 patent/US6084090A/en not_active Expired - Fee Related
-
1998
- 1998-09-03 JP JP2000510858A patent/JP2002509692A/ja not_active Withdrawn
- 1998-09-03 CA CA002302148A patent/CA2302148A1/en not_active Abandoned
- 1998-09-03 WO PCT/US1998/018320 patent/WO1999013071A1/en not_active Ceased
- 1998-09-03 EP EP05009714A patent/EP1595954A1/en not_active Withdrawn
- 1998-09-03 EP EP98944709A patent/EP1009823A1/en not_active Withdrawn
- 1998-09-03 KR KR1020007002392A patent/KR100604218B1/ko not_active Expired - Fee Related
- 1998-09-03 AU AU92183/98A patent/AU9218398A/en not_active Abandoned
-
2000
- 2000-04-28 US US09/560,579 patent/US6277980B1/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993020095A1 (en) * | 1992-03-31 | 1993-10-14 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide inhibition of papillomavirus |
| WO1995031552A2 (en) * | 1994-05-13 | 1995-11-23 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Human papilloma virus inhibition by a hairpin ribozyme |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1009823A1 (en) | 2000-06-21 |
| AU9218398A (en) | 1999-03-29 |
| WO1999013071A1 (en) | 1999-03-18 |
| EP1595954A1 (en) | 2005-11-16 |
| CA2302148A1 (en) | 1999-03-18 |
| US6084090A (en) | 2000-07-04 |
| JP2002509692A (ja) | 2002-04-02 |
| KR20010015573A (ko) | 2001-02-26 |
| US6277980B1 (en) | 2001-08-21 |
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