KR100550470B1 - A heating and cooling exchange apparatus and method system using one exchange fluid in the chemical reactor - Google Patents

Abstract

The present invention is to install a temperature automatic control device in the reactor, to improve the yield of the reaction product by comprehensively precisely controlling the temperature deviation of the heat exchange medium flowing in and out to perform the heating and cooling of the material inside the reactor, the endothermic and exothermic reaction The present invention relates to a temperature control device and a method using a single medium for a chemical process reactor that can immediately cope with the back.

The present invention comprises a jacket having an inlet and an outlet and installed around the reactor for exchanging the reactant temperature charged therein with a heat exchange medium; A heat exchange medium circulation line connected to the jacket to provide a circulation path for circulation of the heat exchange medium; Heat exchange medium supply means for supplying a heat exchange medium to the jacket through the heat exchange medium circulation line; Heating means installed at a predetermined position on the heat exchange medium circulation line and configured to heat the heat exchange medium provided from the heat exchange medium supply means to a predetermined temperature and supply the same to the jacket side; First heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line, and configured to heat the circulating heat exchange medium to a desired normal temperature by a first refrigerant provided from an external cooling tower to supply to the jacket side; Second heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line and configured to heat the circulating heat exchange medium to a desired subzero temperature by a second refrigerant provided from an external refrigerator to supply to the jacket side; Moving path converting means installed in a heat exchange medium circulation line connecting the first heat exchanging medium cooling means and the second heat exchanging medium cooling means, respectively, to convert a moving path of the heat exchanging medium; And controlling means for controlling the temperature of the heat exchanging medium circulated to the heat exchanging medium circulation line and controlling the operation of each of the various devices.

Heat exchanger, heat exchange medium, reactor, temperature control unit, electric heater, 3-way valve

Description

Temperature control apparatus and method using a single medium for chemical process reactors {A heating and cooling exchange apparatus and method system using one exchange fluid in the chemical reactor}             

1 is a schematic diagram showing the configuration of a heat exchange system for a chemical process reactor according to the prior art.

Figure 2 is a schematic process diagram showing an embodiment of a temperature control device using a single medium for a chemical process reactor according to the present invention.

* Explanation of symbols for the main parts of the drawings

1: jacket 2: expansion container

3: oil circulation line 4: motor pump

5: electric heater 6, 7: first and second heat exchanger

8: 3-way valve 9, 10: 1st and 2nd oil temperature sensor

11: Temperature control unit 12: Cooling medium line

13: quenching medium line 14: solenoid valve

15: temperature control valve 16, 17: first and second valve

100: reactor

The present invention relates to a heat exchange system used in a chemical process reactor, and more specifically, a single fluid for a chemical process reactor, which uses only a single fluid as a heat exchange medium, and can heat exchange the temperature in the reactor to an optimized state through a temperature control unit. It relates to a temperature control device and a method using a medium.

In general, the flow of the synthesis reaction in a pharmaceutical plant or a fine chemical plant, etc., generally goes from the manual operation of the equipment to semi-automation to the automation stage. This is essential to increase the efficiency of production in pilot production and mass production.

Therefore, in the chemical process reactor, it is necessary to precisely control the reaction temperature in order to produce a uniform product, increase production efficiency, and stabilize quality. These reactors are somewhat different depending on the reaction process, but usually take a heat exchange method to control the internal temperature, heat exchange equipment for temperature control, such as steam (hot water), cooling water (cooling water), cooling oil ( brine) facilities as basic equipment.

Then, a brief description of the heat exchange system for a chemical process reactor according to the prior art with reference to FIG.

As shown in the figure, a jacket 101 is provided around the reactor 100 to circulate the heat exchange medium to heat or cool the reactants in the reactor. The jacket 101 is provided with a refrigerant, steam, cooling water, and the like. The main transfer line 102 for flowing in and out the heat exchange medium is connected. The main transfer line (102) has a cooling tower (111) for supplying general industrial water as a cooling medium, a freezer (112) for cooling oil (brine) as a freezing medium, and a steam generator for converting and supplying ground water to steam ( 113 are each connected. In addition, the main transfer line 102 and the branch line is provided with a manual valve 115 for controlling the supply of the heat exchange medium. Temperature sensors 116 are respectively installed in the main transfer line 102, and signals output from these temperature sensors 116 are input to the main control room 120.

In the conventional reactor temperature control device configured as described above, the reactor 100 and the heat exchange medium supply device are installed far from each other, and the heat exchange medium supplied to the reactor 100 according to the temperature detection signal input to the main control room 120. After checking the temperature, the skilled person manually manipulates the manual valve 115 installed in each main transfer line 102 and the branch line to control the supply of the heat exchange medium to control the temperature of the reactor that exchanges heat with the heat exchange medium. .

As such, the conventional reactor temperature controller includes various problems as described below.

Firstly, the temperature in the reactor is controlled within the range of ± 10 ° C by controlling the supply of heat exchange medium by manual operation of a valve by a skilled worker. Therefore, the experience value of opening and closing the manual valve is different for each skilled person, and the control ability can vary greatly according to the control procedure, so that the temperature in the reactor cannot be uniformly controlled. This makes it difficult to realize the same reproducibility of the reaction product, which greatly affects the yield and precision of the reaction product.

Secondly, continuous manual control for the reaction temperature is required, so a skilled worker must always be present at the site, which requires a lot of maintenance cost, and regular replacement of cooling oil is necessary to change thermal characteristics and maintain optimal operating conditions. This incurs environmental treatment costs.

Third, when the manual valve is operated, a sudden temperature change may cause a temperature shock, which may cause damage to the reactor.

Fourth, the heat exchange medium such as cooling oil, cooling water, steam, etc. should be used according to the reaction materials in the reactor, and the usable range is limited to -52 ° C to 150 ° C. In addition, since the vapor pressure (normally 10㎏ / ㎠) at 250 ℃ is large, there is a high risk, and since the oxidizing material is contained in the heat exchange medium greatly affects the corrosion of the pipe, should be replaced every two years.

Fifth, since various types of heat exchange media are used, these heat exchange media contain toxic substances and thus cannot be used in food manufacturing or clinical laboratory pharmaceutical manufacturing processes, and are only limited to reaction processes that produce unrelated or harmless reactants. Can be applied as

Therefore, the present invention has been proposed to solve the above problems, and install a temperature automatic control device in the reactor, the overall temperature deviation of the heat exchange medium flows in and out to perform the heating and cooling function of the material inside the reactor The purpose of the present invention is to provide a temperature control device and a method using a single medium for a chemical process reactor that can improve the yield of the reaction product and immediately cope with endothermic and exothermic reactions by precise control.

In addition, the present invention can form a wide range of reaction temperature than conventional by using a single fluid, such as alkylbenzene or silicone oil, which is harmless to the human body as a heat exchange medium, regardless of the reactants in the reactor to obtain a variety of reaction products, food Another object of the present invention is to provide a temperature control device and a method using a single medium for a chemical process reactor that can be applied to a manufacturing process or a clinical product experiment manufacturing process.

The present invention for achieving the above object, the inlet and outlet having a jacket installed around the reactor for filling the inside of the reactant temperature exchanged with the heat exchange medium; A heat exchange medium circulation line connected to the jacket to provide a circulation path for circulation of the heat exchange medium; Heat exchange medium supply means for supplying a heat exchange medium to the jacket through the heat exchange medium circulation line; Heating means installed at a predetermined position on the heat exchange medium circulation line to heat the heat exchange medium provided from the heat exchange medium supply means to a predetermined temperature and supply the same to the jacket side; First heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line, and configured to heat the circulating heat exchange medium to a desired normal temperature by a first refrigerant provided from an external cooling tower to supply to the jacket side; Second heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line and configured to heat the circulating heat exchange medium to a desired subzero temperature by a second refrigerant provided from an external refrigerator to supply to the jacket side; Moving path converting means installed in a heat exchange medium circulation line connecting the first heat exchanging medium cooling means and the second heat exchanging medium cooling means, respectively, to convert a moving path of the heat exchanging medium; And it provides a temperature control apparatus using a single medium for a chemical process reactor including a control means for controlling the temperature of the heat exchange medium circulated to the heat exchange medium circulation line, and controls the operation of each of the various equipment.

In addition, the present invention is a first step of supplying a heat exchange medium filled in the expansion vessel to the jacket side installed around the reactor through a heat exchange medium circulation line; It detects the temperature of the heat exchange medium flowing on the heat exchange medium circulation line and inputs it to the temperature control unit, and selects a 3-way valve by controlling the temperature of the heat exchange medium flowing in the outlet line of the input heat exchange medium circulation line and the temperature deviation in the reactor. A second step of opening and closing with; When the reactant in the reactor is to be maintained at a high temperature, the heater is operated by a control signal of a temperature control unit, the heat exchange medium flowing through the heat exchange medium circulation line is heated to a predetermined temperature, and then supplied to the jacket to supply the reactant in the reactor. A third step of heat exchange with; A fourth step of stopping the operation of the heater by a control signal of a temperature control unit and converting the opening / closing path of the three-way valve to the first heat exchanger line side path when the reactant in the reactor is to be maintained at room temperature; A fifth step of performing a fourth step, introducing a heat exchange medium circulating through the jacket into the first heat exchanger, exchanging heat with the refrigerant at room temperature provided by the cooling tower, and then sending the heat exchange medium to the jacket; A sixth step of quenching the reactants in the reactor, stopping the operation of the heater by a control signal of a temperature control unit, and converting an opening / closing path of the three-way valve to a second heat exchanger line side path; And after performing the sixth step, introducing a heat exchange medium circulating through the jacket into the second heat exchanger to exchange heat with the sub-zero refrigerant provided by the freezer, and then sending the heat exchange medium to the jacket. Provide temperature control method.

The above objects, features and advantages will become more apparent from the following detailed description taken in conjunction with the accompanying drawings. Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

Temperature control device and method using a single medium for a chemical process reactor according to the present invention to automatically control the reaction temperature in the reactor to heat exchange within a predetermined temperature difference range to improve the yield of the reaction product and to extend the life of the reactor It is an implementation.

In the embodiment of the present invention, a single heat exchange medium is used. In other words, in the present invention, a heat exchange medium that converts groundwater into steam as a high temperature medium, a cooling medium using general industrial water as a cooling medium, and a cooling oil quenched in a freezer as a quenching medium are used. A structure using a selected one of alkylbenzene and silicon (hereinafter referred to as "oil") capable of heat exchange in the range of -100 ° C to 360 ° C as a heat exchange medium is disclosed.

In the present invention, as shown in Figure 2, having an inlet (1a) and an outlet (1b) is installed around the reactor 100 and the jacket (1) for heat-exchanging the reactant temperature charged therein with the oil temperature; ; An expansion container (2) for supplying the oil to the jacket (1) inherently; An oil circulation line (3) for supplying the oil provided from the expansion container (2) to the jacket (1) and providing a circulation path for the oil discharged from the jacket to circulate and re-introduce into the jacket; A motor pump 4 installed on the oil circulation line 3 for delivering oil supplied from the expansion vessel 2; An electric heater (5) installed on the oil circulation line (4) on one side of the motor pump (4) to heat oil to a predetermined temperature and to send it to the jacket (1) side; First and second heat exchangers (6, 7) connected to the other oil circulation lines (5) of the motor pump (4) in parallel and heat-exchanging the circulated oil at a desired temperature to be discharged to the jacket side; It is installed on the oil circulation line 3 between the motor pump 4 and the first and second heat exchangers 6, 7, and the electric heater 5, the first and second heat exchangers 6, 7. A three-way valve 8 for selectively controlling a movement path of the oil having passed through; First and second oil temperature sensors 9 and 10 installed on the inlet line and the outlet side line of the oil circulation line 3 to sense the temperature of the circulating oil; And a temperature control unit 11 for controlling the operation of the electric heater 5 and the opening and closing of the three-way valve 8 by receiving the detection signals of the first and second oil temperature sensors 9 and 10.

The first heat exchanger 6 is connected with a cooling medium line 12 for supplying cooling water from a cooling tower (not shown), and the second heat exchanger 7 supplies a refrigerant from a freezer (not shown). Quench medium line 13 is connected. The flow of the cooling water through the cooling medium line 12 and the quench medium line 13 is discharged after passing through the first and second heat exchangers 6 and 7, respectively. Heat exchange with oil passing through groups (6, 7).

In addition, on the line section connecting the first and second heat exchangers 6 and 7 and the three-way valve 8, the first and second valves 16 and 17 to open and close the heat exchanged oil so as to control the supply. ) Is installed.

In the present exemplary embodiment, general cooling water or industrial water is used as the cooling medium passing through the cooling medium line 12, and cooling oil (brine) is used as the quenching medium passing through the quenching medium line 13. . On the inlet side line of the cooling medium line 12, a solenoid valve 14 which is opened and closed by an external control signal is provided, and on the inlet side line of the quench medium line 13 by an external control operation. An operating temperature control valve 15 is installed. Here, the solenoid valve 14 and the temperature control valve 15 may be automatically opened and closed operation by the control signal of the temperature control unit (11).

As described above, since the cooling medium provided in the cooling tower and the quenching medium provided in the freezer are discharged after passing through only the first and second heat exchangers 6 and 7, the oil circulation line 3 may be scaled or corroded. As a result, the pipe replacement cycle can be lengthened, and the oil temperature can be controlled reliably.

Referring to the working state of the present invention configured as described above are as follows.

First, in the expansion container 2, oil, which is a heat exchange medium for heating or cooling, is embedded. The oil is supplied through the oil circulation line 3 by the operation of the motor pump 4. It is supplied to the jacket 1 side.

When the reactant in the reactor 100 is to maintain a high temperature state, the electric heater 5 is operated by the control signal of the temperature control unit 11, the oil flowing through the oil circulation line 3 is the electric heater It is heated at (5) and flows into the inlet 1a of the jacket 1. The oil heated in the electric heater 5 is detected by the first temperature sensor 9, and this detection signal is applied to the temperature control unit 1 to control the operation of the electric heater 5. That is, the electric heater until the temperature control unit 11 reaches the desired heat exchange target temperature by controlling the temperature according to the operation of the electric heater 5 in order to heat exchange the reactant temperature in the reactor 1 to a desired high temperature. It is to control the operation of (5).

The oil heated in the electric heater (5) is introduced into the jacket (1) to heat exchange with the endothermic reaction to the reactants in the reactor (1), and then through the outlet (1b) of the jacket (1) oil circulation line (3) Circulation to the outlet line. The oil flowing through the outflow line of the oil circulation line 3 is sensed by the second temperature sensor 10, and this detection signal is applied to the temperature control unit 11.

The oil circulating in the oil circulation line 3 is controlled through a three-way valve 8. That is, while the electric heater 5 is operating, all of the lines connected to the first heat exchanger 6 side and the second heat exchanger 7 side are shielded, and are heated only by the operation of the electric heater 5. Only oil is circulated to the jacket (1).

Next, in the case of cooling the reactant temperature in the reactor 100 to room temperature state, that is, to cool the temperature of the reactant heated by the electric heater 5 to maintain a high temperature state at room temperature, the temperature control unit The oil temperature on the outflow line inputted in (11) and the temperature deviation in the reactor are controlled. At this time, the operation of the electric heater (5) is stopped, the three-way valve (8) shields the heating oil supply line path, and at the same time open the cooling oil supply line path, thereby the oil flowing to the outflow circulation line Is introduced into the first heat exchanger and the second heat exchanger.

In addition, a solenoid valve 12 installed on a cooling medium line connecting the cooling tower and the first heat exchanger 6 and a first installed on a line connecting the first heat exchanger 6 and the three-way valve 8. The valve 16 is opened by the control signal of the temperature control unit 11. On the other hand, since the temperature control valve 15 and the second valve 17 connected on the quench medium line remain shielded, the oil flowing into the second heat exchanger 7 does not exchange heat, and the three-way valve 8 It will not flow to the side.

As such, the coolant flows into the first heat exchanger 6 by opening the solenoid valve 12 to perform heat exchange with oil, and the heat-exchanged oil passes through the three-way valve 8 to the jacket 1. The reactant is maintained at room temperature by being sent out and heat exchanged with the reactant in the reactor 100.

In the case of quenching the reactant temperature in the reactor 100, the temperature control unit 11 controls the oil temperature on the input outflow line and the temperature deviation in the reactor 100. At this time, the operation stop of the electric heater (5) and the cooling oil supply line path open state of the three-way valve (8) continues to be maintained. The solenoid valve 12 and the first valve 16 are shielded, and the temperature control valve 13 and the second valve 17 are opened. Accordingly, the oil flowing into the outlet circulation line flows into the first heat exchanger and the second heat exchanger, but the oil passing through the first heat exchanger does not flow to the three-way valve side by the shielding of the first valve 16, and only the second heat exchanger ( Only the oil having passed through 7) flows to the three-way valve 8 side.

As such, the cooling oil, which is a quenching medium, flows into the second heat exchanger 6 by opening the temperature control valve 13 to perform heat exchange with the oil, and the heat exchanged oil is a three-way valve 8. It is sent to the jacket (1) through the heat exchange to quench the reactants in the reactor (100).

As can be seen in the above operation, only a single oil is used as the medium for heating or cooling the reactants in the reactor 100. The heating and cooling of the oil is performed by the electric heater 5 and the first and second heat exchangers 6 , Precisely controlled by operation of 7).

The present invention described above is not limited to the above-described embodiment and the accompanying drawings, and will be apparent to those skilled in the art without departing from the technical spirit of the present invention.

As described above, according to the present invention, by controlling the temperature deviation of the heat exchange medium by the temperature control unit installed in the reactor, it is possible to match the resultant product during repeated production, so that the yield of the reaction product during the test production or mass production It can improve the performance, minimize the errors that can occur during production, and have the effect of dealing with the endothermic and exothermic reactions immediately.

In addition, the present invention can perform a reaction process in the reaction temperature range of -100 ℃ to 360 ℃ irrespective of the reactants in the reactor to obtain a variety of reaction products, food by using only a single heat exchange medium harmless to the human body Not only can be applied to the manufacturing process or clinical product manufacturing process, but also to maintain the steam pressure range at high temperature lower than before to ensure the stability and have other effects without affecting the environment.

In addition, the present invention not only reduces maintenance costs because of controlling a single fluid temperature by the temperature control unit, but also has another effect of extending the periodic replacement cycle of the reactor.

In addition, the present invention can control the heat exchange medium heated by the electric heater at a low pressure (usually 4.21kg / ㎠) has another effect that can be operated stably.

Claims (12)

A jacket installed around the reactor with an inlet and an outlet for exchanging the reactant temperature charged therein with the heat exchange medium; A heat exchange medium circulation line connected to the jacket to provide a circulation path for circulation of the heat exchange medium; Heat exchange medium supply means for supplying a heat exchange medium to the jacket through the heat exchange medium circulation line; Heating means installed at a predetermined position on the heat exchange medium circulation line and configured to heat the heat exchange medium provided from the heat exchange medium supply means to a predetermined temperature and supply the same to the jacket side; First heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line, and configured to heat the circulating heat exchange medium to a desired normal temperature by a first refrigerant provided from an external cooling tower to supply to the jacket side; Second heat exchange medium cooling means installed at a predetermined position on the heat exchange medium circulation line and configured to heat the circulating heat exchange medium to a desired subzero temperature by a second refrigerant provided from an external refrigerator to supply to the jacket side; Moving path converting means installed in a heat exchange medium circulation line connecting the first heat exchanging medium cooling means and the second heat exchanging medium cooling means, respectively, to convert a moving path of the heat exchanging medium; And Control means for controlling the temperature of the heat exchange medium circulated in the heat exchange medium circulation line, and controls the operation of each machine Temperature control device using a single medium for a chemical process reactor comprising a. The method of claim 1, Temperature control device using a single medium for a chemical process reactor, characterized in that the heat exchange medium has a temperature range of -100 ℃ ~ 360 ℃. The method of claim 2, Temperature control device using a single medium for a chemical process reactor, characterized in that the heat exchange medium is made of one selected from alkyl benzene or silicone oil. The method of claim 1, Temperature control device using a single medium for a chemical process reactor, characterized in that the heating means is an electric heater. The method according to any one of claims 1 to 4, The control means A temperature sensor installed at each of the inlet line and the outlet line of the heat exchange medium circulation line to sense the temperature of the heat exchange medium; Receives a sensing signal output from the temperature sensor, controls the start and stop of the heating means according to the heat exchange temperature required by the reactor, controls the opening and closing path of the movement path conversion means, supply the first and second heat exchange medium Temperature control unit for controlling the supply of heat exchange medium through the means Temperature control apparatus using a single medium for a chemical process reactor comprising a. The method according to any one of claims 1 to 4, The first heat exchange medium supply means  A first heat exchanger connected to a cooling medium line for supplying a first refrigerant from an external cooling tower to heat exchange between the first refrigerant and the heat exchange medium; A solenoid valve installed on the cooling medium line and opened / closed by an external control signal to supply a first refrigerant to a first heat exchanger; And a first valve installed on a line section connecting the first heat exchanger and the movement path converting means to control the supply of the heat exchanged heat exchange medium. The second heat exchange medium supply means includes a second heat exchanger connected to a rapid cooling medium line for supplying the second refrigerant from the freezer to heat exchange between the second refrigerant and the heat exchange medium; A temperature control valve installed on the quenching medium line and opened and closed by an external control signal to supply a second refrigerant to the second heat exchanger; And a second valve installed on a line section connecting the second heat exchanger and the movement path converting means to control the supply of the heat exchanged heat exchange medium. The method of claim 6, The first refrigerant is made of cooling water for maintaining the heat exchange medium at room temperature, and the second refrigerant is a cooling oil (brine) for maintaining the heat exchange medium at sub-zero temperature. Thermostat. The method according to any one of claims 1 to 4, Temperature control device using a single medium for the chemical process reactor, characterized in that the moving direction conversion means is a three-way valve. A first step of supplying a heat exchange medium filled in the expansion container to a jacket side installed around the reactor through a heat exchange medium circulation line; It detects the temperature of the heat exchange medium flowing on the heat exchange medium circulation line and inputs it to the temperature control unit, and selects a 3-way valve by controlling the temperature of the heat exchange medium flowing in the outlet line of the input heat exchange medium circulation line and the temperature deviation in the reactor. A second step of opening and closing with; When the reactant in the reactor is to be maintained at a high temperature, the heater is operated by a control signal of a temperature control unit, the heat exchange medium flowing through the heat exchange medium circulation line is heated to a predetermined temperature, and then supplied to the jacket to supply the reactant in the reactor. A third step of heat exchange with; A fourth step of stopping the operation of the heater by a control signal of a temperature control unit and converting the opening / closing path of the three-way valve to the first heat exchanger line side path when the reactant in the reactor is to be maintained at room temperature; A fifth step of performing a fourth step, introducing a heat exchange medium circulating through the jacket into the first heat exchanger, exchanging heat with the refrigerant at room temperature provided by the cooling tower, and then sending the heat exchange medium to the jacket; A sixth step of quenching the reactants in the reactor, stopping the operation of the heater by a control signal of a temperature control unit, and converting an opening / closing path of the three-way valve to a second heat exchanger line side path; And After performing the sixth step, the heat exchange medium circulating the jacket is introduced into the second heat exchanger to heat exchange with the sub-zero refrigerant provided in the freezer, and then sent to the jacket Temperature control method using a single medium for a chemical process reactor comprising a. The method of claim 9, The third step is When the heater is in operation, a three-way valve in a path communicating with these lines is shielded to prevent the heat exchange medium from flowing through the lines connected to the first heat exchanger side and the second heat exchanger side, and the target heat exchange target temperature in the reactor is desired. Temperature control method using a single medium for a chemical process reactor, characterized in that for operating the heater until it reaches. The method of claim 9, The fifth step is And opening the solenoid valve installed on the cooling medium line connecting the cooling tower and the first heat exchanger and the first valve installed on the line connecting the first heat exchanger and the three-way valve by a control signal of a temperature control unit. Temperature control method using a single medium for a chemical process reactor. The method of claim 9, The seventh step Opening the temperature control valve valve installed on the quench medium line connecting the refrigerator and the second heat exchanger and the second valve installed on the line connecting the second heat exchanger and the three-way valve by a control signal of the temperature control unit; Temperature control method using a single medium for a chemical process reactor comprising a.

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