KR100526944B1 - Dandelion granular tea and process for preparing the same - Google Patents

Abstract

The present invention relates to a dandelion granule tea comprising a dandelion leaf extract, dandelion root extract, lettuce extract and sugar extract and a method for producing the same. Method for producing dandelion granulated tea of the present invention (i) 100 parts by weight of glucose, 9 to 12 parts by weight of dandelion leaf hot water extract of 50 to 70 Brix, 3 to 4 parts by weight of dandelion root hot water extract of 50 to 70 Brix, 50 to 70 Brix Mixing 2 to 4 parts by weight of hot water extract and 2 to 4 parts by weight of 50 to 70 Brix of sugar ginseng hot water extract; (Ii) concentrating and granulating the mixture to obtain granules; And (iii) drying the obtained granules. Dandelion granule tea of the present invention is not only excellent dementia prevention effect, but also excellent palatability, it can be widely used as a functional food for preventing dementia.

Description

Dandelion Granular Tea and Process for Preparing the Same

The present invention relates to a dandelion granulated tea and a method of manufacturing the same. More specifically, the present invention relates to a dandelion granule tea comprising a dandelion leaf extract, dandelion root extract, lettuce extract and sugar extract and a method for producing the same.

Geriatric dementia is known to be caused by β-amyloid peptides in the brain of the patient to form neurofibrillary bundles with the senile plaques and to advance degenerative lesions of various nervous systems such as the choline nervous system. Currently, about 10% of the elderly aged 65 or older, about 25% of the aged 75 or older, and about 50% of the aged aged 85 or older are suffering from senile dementia. As expected, dementia disease is emerging as the biggest health problem facing humanity. When senile dementia develops, it has been confirmed that neurotransmitters such as acetylcholine in the brain are reduced, and is developed to alleviate symptoms of senile dementia by promoting choline function in the brain. Although tacrine and ENA 713, which are commercially available inhibitors of acetylcholine esterase (AChE), have been used as treatments for dementia, the effectiveness of these drugs in the clinical practice and the development of severe symptoms of dementia are low. The situation is being used to delay.

Given that the damage to the central nervous system caused by dementia is irreversible, the most effective way to treat dementia is to inhibit the production of beta amyloid plaques that are characteristic of the brains of dementia patients. It is to prevent neuronal death by beta amyloid. Since electric plaques are known to induce neuronal cell loss and expression of dementia, it may be possible to prevent the development and progression of dementia by inhibiting the production of beta amyloid plaques or reducing their accumulation in the brain. It is expected to be. Accordingly, studies are actively conducted to find a substance that can inhibit the formation of beta amyloid plaques. As a result, a vaccine using attenuated beta amyloid has been reported to be effective, but side effects such as brain damage and immune rejection reactions have been reported. This fatal issue has emerged

Therefore, it is possible to prevent the development and progression of dementia by inhibiting the formation of beta amyloid plaques in the brain, and to feed on foods containing substances that can be common sense without side effects, thereby preventing dementia without side effects. Although it is expected to be expected, no results have been reported so far.

Therefore, the necessity to develop a substance that can suppress the onset and progress of dementia, and ensure safety and common sense without side effects has emerged constantly.

Thus, the present inventors can suppress the development and progression of dementia, and as a result of earnest research to develop a substance that can secure common sense without side effects as a result of safety, dandelion commercially available as a herbal medicine from whales in β-amyloid peptide It shows the effect of inhibiting the damage of nerve cells caused by, and when the extract obtained from baekryepi and ginseng used as a medicinal herb was found to double the effect of the electric dandelion, utilizing the effects of electric dandelion, baekryepi and sugar ginseng In order to produce a dandelion granule tea comprising a dandelion extract, an extract of lettuce and extract of Dangsam, it was confirmed that the electric dandelion granule tea can suppress the onset and progression of dementia without side effects, and completed the present invention.

After all, the main object of the present invention is to provide a dandelion granule tea, including dandelion extract, lettuce extract, and ginseng extract, exhibiting a dementia prevention effect.

Another object of the present invention is to provide a method for producing an electric dandelion granular tea.

Method for producing dandelion granulated tea of the present invention (i) 100 parts by weight of glucose, 9 to 12 parts by weight of dandelion leaf hot water extract of 50 to 70 Brix, 3 to 4 parts by weight of dandelion root hot water extract of 50 to 70 Brix, 50 to 70 Brix Mixing 2 to 4 parts by weight of hot water extract and 2 to 4 parts by weight of 50 to 70 Brix of sugar ginseng hot water extract; (Ii) concentrating and granulating the mixture to obtain granules; And (iii) drying the obtained granules.

Dandelion ( Taraxacum herba ) is a perennial herb belonging to the genus Apothecara, also known as Pogongyoung, and is widely distributed throughout Korea from early spring to late autumn. From ancient times, dandelion has been known as one of the few herbs that can medicinal all the plants, such as roots, leaves, flowers, stems.

In oriental medicine, the taste of dandelion is bitter and salty, and the property is flat and it is evaluated that it is not poisonous. Dongbogam describes dandelion as a fever, detoxification, diuresis, and the most effective effect, it is used for the treatment of liver and gallbladder disease, to relieve the ulcers and to relieve inflammation or boil. ) Dandelion juice continued to darken the hair and to strengthen the stomach and bones. It is possible to use both externally and externally, and the effect is stated to be very large. In addition, according to folk remedies, dandelion has been used in tonic, antipyretic, diuretic, healthy, expectorant, antidote, etc., and is also used in the West as a drug for promoting bile secretion, antirheumatic, diuretic and the like.

The present inventors have been studying to develop a substance that can suppress the development and progression of dementia without side effects in the body, and the effect of dandelion, which has been commonly used as a medicinal herb from whales, suppresses the damage of nerve cells by β-amyloid peptide. Effect of dandelion on inhibiting neuronal cell damage caused by β-amyloid peptides of lettuce and red ginseng, which are herbal medicines showing inhibitory activity against acetylcholine esterase (AChE), which is known to be related to the progression of dementia symptoms It could be confirmed that hungry.

From the above results, the present inventors have been found that the use of dandelion, baekryepi and ginseng showed dementia-preventing effect, as a result of trying to prepare them in the form of various foods that can be common sense without side effects, dandelion leaves Dandelion granulated tea comprising the extract, dandelion root extract, lettuce extract, and ginseng extract was prepared, and it was confirmed that the dandelion granulated tea, which was previously prepared, can effectively inhibit neuronal damage caused by β-amyloid peptide: The content of the dandelion leaf extract added to the dandelion granule tea is not particularly limited thereto, but is preferably added in an amount of 9 to 12 parts by weight based on 100 parts by weight of sugar, and the content of the dandelion root extract is not particularly limited thereto, but is 100 parts by weight of sugar. It is preferably added in an amount of 3 to 4 parts by weight, The content of the liquid is not particularly limited thereto, but is preferably added in an amount of 2 to 4 parts by weight based on 100 parts by weight of sugar, and the content of the extract is not particularly limited thereto, but is added in an amount of 2 to 4 parts by weight based on 100 parts by weight of sugar. Is preferred.

Dandelion granular tea of the present invention can effectively inhibit the damage of neurons by β-amyloid peptide, and also has excellent palatability, and thus can be widely used as a functional food for preventing dementia.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, it will be apparent to those skilled in the art that the scope of the present invention is not limited to these examples.

Example 1 Preparation of Dandelion Extract and Analysis of Dementia Prevention Effect

Example 1-1 Preparation of Dandelion Extract

Extracts were prepared using methanol to lyophilized powder for each part of the dandelion. That is, 5 g of the powders (leaves and roots) of the white and yellow dandelions were suspended in 100 mL of 75% (v / v) aqueous methanol solution, respectively, and then refluxed at 80 ° C. for 3 hours and filtered to obtain liquid components. Was concentrated in a vacuum concentrator at 45 ℃, and then lyophilized to prepare a dandelion extract.

Example 1-2 : Dementia Prevention Effect Analysis of Dandelion Extract

Cerebral nerve cancer-derived cell line SK-N-SH (MedXBio Inc., USA) was cultured in neuronal cell culture medium (10% (v / v) FBS, 1 mM sodium pyruvate, 1% penicillin-streptomycin, Dulbecco modified Eagle's minimum essential medium (DMEM)). The cells were divided into 5 × 10 ⁵ cells / mL, and cultured in a single layer, replacing the medium twice a week in a 37 ° C., 5% (v / v) CO ₂ incubator. The cultured cells were treated with 40 μM of β-amyloid peptide _1-42 (βA, American Peptide Company, USA), and each of the dandelion extracts prepared at the concentrations of 0.01, 0.05, 0.1, 0.25 and 0.5 mg / ml. After treatment, the survival rate of neurons was measured. At this time, βA and dandelion extract were treated as a negative control neuron, and a positive control was used as a dandelion extract untreated neuron.

In addition, the survival rate of the electric neurons was measured by counting the number of viable cells according to the MTT (3- (4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazoliumbromide) assay: that is, each of the cultured cells The cells were crushed to obtain a cell suspension, 100 μL of MTT solution (2.5 mg / mL H ₂ O) was added to the suspension and reacted at 37 ° C. for 4 hours, followed by centrifugation at 1500 rpm to obtain a precipitate. 100 μL of dimethyl sulfoxide (DMSO) was added to the precipitate to dissolve the precipitate and the absorbance was measured at 540 nm (see Table 1).

Dandelion extract and survival rate of neurons according to its concentration (%) Dandelion extract 0.01mg / ml 0.05mg / ml 0.1mg / ml 0.25mg / ml 0.5mg / ml Negative control 100 100 100 100 100 Positive control 60 60 60 60 60 White dandelion leaf 68 72 65 67 100 White dandelion root 61 61 62 68 78 Yellow dandelion leaf 61 71 75 82 100 Yellow dandelion root 61 65 68 73 100

As shown in Table 1, in the case of leaves of white dandelion and yellow dandelion, even if the extract of very low concentration of 0.5mg / mL was added to the cell survival rate was restored to the normal control level, even at a concentration of 0.05mg / mL lower than this high Survival was shown. However, it was found that yellow dandelions showed higher survival rates than white dandelions.

Example 2 Screening of Herbal Medicines Having Inhibitory Activity of Acetylcholine Esterase (AChE)

Example 2-1 : Search for herbal medicines having AChE inhibitory activity

5 g of 20 herbal medicines were suspended in 100 mL of 75% methanol, refluxed at 80 ° C. for 3 hours, the filtrate was concentrated in a 45 ° C. vacuum concentrator, and lyophilized to obtain each extract.

AChE inhibitory activity was determined by the following methods: 170 uL of 0.1 M phosphate buffer (pH 8.0), 20 uL of 2 mM dithiobisnitrobenzoic acid, 0.5, 1, 2.5 and 5 mg / ml of the extract obtained above. 20 uL of a solution dissolved in 1 ml of methanol and 230 uL of a mixture of 20 uL of AChE (0.2 unit) was pretreated at 37 ° C. for 10 minutes, 20 uL of 3.75 mM acetylcholine iodide was added, and then 30 minutes at 37 ° C. The reaction was carried out and the absorbance (A) was measured at 410 nm. In addition, the absorbance (B) was measured at 410 nm of a mixed solution of 20 M of a solution in which 0.1 M phosphate buffer (pH 8.0) and the previously obtained extract were dissolved in 1 ml of methanol at concentrations of 0.5, 1, 2.5 and 5 mg / ml. In addition, as a control, using the absorbance measured in methanol 410nm, AChE inhibitory activity was measured by the following formula (see Table 2).

AChE Inhibitory Activity of Various Medicinal Herb Extracts (Unit:%) Herbal medicine 0.5mg / ml 1mg / ml 2.5mg / ml 5mg / ml Donkey - 5.5 10.1 18.7 Dangsam 0.4 10.7 31.1 62.1 Poisonous - - 3.9 13.0 Tofu - - 11.5 14.6 Macmundong 11.1 13.3 12.9 8.0 Earl - 7.0 33.5 60.2 Whiteness - - - 6.5 Ghost - - - 5.5 Sansa - - 11.5 30.6 Mountain lion - - 2.9 15.3 White skin 56.2 76.3 81.9 85.9 Sesin - - - - Hungjiwang - 1.8 6.8 8.3 Paper - - - - Phosphoric Acid - - 1.5 16.2 dermis 11.1 - - 11.9 Cheongung - 2.9 12.8 28.9 Gardenia - - 8.0 20.0 Tosa - - 2.3 9.2 enjoyment - - 1.9 18.7

As shown in Table 2, it was found that the extracts of Ginseng extract, Baekjak extract, and the extract of Morus alba showed excellent AChE inhibitory activity.

Example 2-2 : Synergy Analysis of AChE Inhibitory Activity in the Mixing of Ginseng Extract, Baekjak Extract, and Cereal Bark Extract

To determine whether synergistic effect on AChE inhibitory activity was obtained when the Ginseng extract, Baekjak extract and Epidermis extract obtained in Example 2-1 were mixed with each other, these extracts were prepared at the extract concentrations of 1 mg / mL and 5 mg / mL. After mixing at the same ratio (1: 1), the inhibitory activity against AChE was measured (see Table 3). At this time, in order to compare synergistic effects, the inhibitory activity against each component's own AChE was used as a control. It was.

Synergistic effect of AChE inhibitory activity of various herbal extract mixtures (%) ingredient 1mg / ml 5mg / ml Dangsam 10.7 62.1 Earl 7.0 60.2 White skin 76.3 85.9 Cereal Skin: Dangsam 79.3 97.8 White pear skin: Earl 39.5 85.1 Dangsam: White Peony 8.3 59.6

As shown in Table 3, the synergistic effect was shown when mixed with the extract of baekbaekpi and sugar extract, but it was found that the inhibitory activity is reduced when mixing the extract of Baekjak, in order to show the AChE inhibitory activity , It was found that it is preferable to use a mixture of lettuce extract and Dangsam extract.

Example 2-3 : Synergy Analysis of AChE Inhibitory Activity in Mixing Dandelion Extract, Ginseng Extract, and Morus Cortex Extract

When adding dandelion extract to the mixture of the extracts of the extract from the former extract and the ginseng extract, it was confirmed whether the synergistic effect on the AChE inhibitory activity: ie 1mg / ml and 5mg of the dandelion extract obtained in Example 1-1 dissolved in methanol at a concentration of / ml, and mixed with the same concentrations of the extracts of the extract of baekhyeol and ginseng in various mixing ratios (10: 0, 7: 3, 5: 5, 3: 7 and 0:10 (v / v)) Then, its AChE inhibitory activity was measured (see Table 4a, Table 4b, Table 4c).

Synergistic Effect on AChE Inhibitory Activity According to the Mixing Ratio of Dandelion Extract and Morus Cortex Extract (Unit:%) Mixed ratio (dandelion: baekbaekpi) 1mg / ml 5mg / ml 10: 0 -5.1 -9.5 7: 3 73.0 90.8 5: 5 85.9 96.3 3: 7 78.0 95.6 0:10 76.3 85.9

Synergistic Effect on AChE Inhibitory Activity According to the Mixing Ratio of Dandelion Extract and Ginseng Extract (Unit:%) Mixed ratio (dandelion: Dangsam) 1mg / ml 5mg / ml 10: 0 -5.1 -9.5 7: 3 13.4 70.7 5: 5 16.3 77.8 3: 7 11.1 64.3 0:10 10.7 62.1

Synergistic Effect on AChE Inhibitory Activity According to the Mixing Ratio of Morus bark Extract and Ginseng Extract (Unit:%) Mixing ratio (Skin white: Ginseng) 1mg / ml 5mg / ml 10: 0 76.3 85.9 7: 3 89.1 100.7 5: 5 79.3 97.8 3: 7 78.1 94.3 0:10 10.7 62.1

As shown in Tables 4a to 4c, using the dandelion extract alone, the inhibition rate at concentrations of 1 mg / mL and 5 mg / mL was -5.1% and -9.5%, respectively, indicating that the dandelion extract had inhibitory activity against AChE. Turned out to be absent. However, when the dandelion extract is mixed with the extract of the lettuce extract or the sugar extract, it can be seen that the inhibition rate is similar to or higher than that of the original extract of the extract. In addition, it was found that the synergistic effect was obtained even when the extract of Morus alba extract and Ginseng extract.

Example 3 Analysis of Dandelion Granule Tea Containing Medicinal Herbs and its Dementia Prevention Effects

As shown in the result of Example 2-3, when the dandelion extract, lettuce extract and sugar extract were mixed, respectively, it was confirmed that the synergistic effect on the AChE inhibitory activity, to prepare a granule tea based on dandelion In addition, it was confirmed whether the dandelion granule tea prepared by the addition of the baekbaekpi extract and the ginseng extract, respectively, can exhibit a dementia prevention effect.

Example 3-1 Preparation of Dandelion Granulated Tea

1 kg of washed yellow dandelion leaves were cut to an appropriate size, dried at 65 ° C., and then ground to a size of about 0.3 cm. The pulverized product was wrapped in a 60-mesh cloth, and 6 times the weight of the pulverized material was added, followed by extraction at 90 ° C. for 6 hours. The extract was filtered through a 200-mesh sieve, and the filtrate was heated to 60 ° Brix. Concentration gave a Dandelion leaf extract of 60 ° Brix. Subsequently, 100 parts by weight of glucose and 15 parts by weight of the dandelion leaf extract were mixed to obtain a mixture, which was then hot-air dried at 45 ° C. to prepare respective dandelion granulated tea, which was used as a control.

Subsequently, except for 1 kg of baekryepi, using the same method as the method of obtaining the dandelion leaf extract, after extracting the extract of 60 ° Brix, 100 parts by weight of electric glucose and dandelion leaf extract 15 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, and 20 parts by weight were added to the mixture by weight, respectively, to obtain dandelion granule tea (Experimental groups 1-1 to 1-12) containing baekbaekpi. Each was prepared.

Also, except for 1 kg of ginseng, the same method as that of the dandelion leaf extract was obtained, and then 60 g Brix sugar extract was obtained, followed by 100 parts by weight of electric glucose and the dandelion leaf extract 15. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, and 20 parts by weight were added to the mixture by weight, respectively, to prepare dandelion granule tea (Experimental group 2-1 to 2-12) containing ginseng. Each was prepared.

In addition, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, and 20 weights of the previously obtained extracts from the extracts of baekhyeolpi and the ginseng extract were mixed with 100 parts by weight of electric glucose and 15 parts by weight of dandelion leaf extract, respectively. Simultaneous addition was performed to prepare dandelion granule tea (Experimental Group 3-1 to 3-12) each containing lettuce and red ginseng.

Example 3-2 Analysis of Prevention of Dementia of Dandelion Granulated Tea

Survival rate of neurons was measured using the method of Example 1-2, except that 5 mg of dandelion granulated tea of each experimental group obtained in Example 3-1 was dissolved in 50 ml of water and used. (See Table 5). In this case, the first control group used neurons without βA and dandelion granular tea, the second control group used neurons treated with only βA, and the third control group with βA and the previous Example 3-1 Neurons treated with the prepared control dandelion granule tea were used.

Survival rate of neurons treated with each dandelion granule tea (%) Experimental group Survival rate Experimental group Survival rate Experimental group Survival rate 1st control group 1-1 Experiment group 1-2 Experiment group 1-3 Experiment group 1-4 Experiment group 1-5 Experiment group 1-6 Experiment group 1-7 Experiment group 1-8 Experiment group 1-9 Experiment group 1-10 Experiment group 1-11 Experiment group 1- 12 100656768727578838891939393 2nd control group 2-1 Experiment group 2-2 Experiment group 2-3 Experiment group 2-4 Experiment group 2-5 Experiment group 2-6 Experiment group 2-7 Experiment group 2-8 Experiment group 2-9 Experiment group 2-10 Experiment group 2-11 Experiment group 2- 12 60656769727476808486888888 3rd control group 3-1 Experiment group 3-2 Experiment group 3-3 Experiment group 3-4 Experiment group 3-5 Experiment group 3-6 Experiment group 3-7 Experiment group 3-8 Experiment group 3-9 Experiment group 3-10 Experiment group 3-11 Experiment group 3- 12 63697366798184889295989898

As shown in Table 5, the dandelion granule tea can improve the survival rate of the neurons even by itself (third control), when synergistic extract or the extract of Ginseng extract shows a synergistic effect to increase the overall survival rate of neurons And it was found. In addition, when the extracts of the extracts of baekbaekpi and ginseng were added in an amount of 10 parts by weight or more (experimental groups 1-11, 1-12, 2-11, 2-12, 3-11 and 3-12), the survival rate was further improved. It did not appear.

Example 3-3 : Sensory test of dandelion granulated tea

200 mg of each dandelion granulated tea prepared in Example 3-1 was dissolved in 100 ml of hot water at 70 ° C., and 20 sensory inspectors were scored 9 points (one point: worst, two points: very bad, three points). : Poor, 4 points: Poor, 5 points: Normal, 6 points: Good, 7 points: Good, 8 points: Very good, 9 points: Best) The sensory test was performed (see Table 6a, table). 6b, Table 6c): At this time, the control dandelion granule tea prepared in Example 3-1 was used as a control.

Sensory Evaluation of Dandelion Granulated Tea Added with Morus alba L. Extract Experimental group Color flavor General Symbol Control group 1-2 Experiment group 1-4 Experiment group 1-6 Experiment group 1-8 Experiment group 1-10 Experiment group 1-12 6.66.06.33.02.92.72.6 6.66.85.14.84.64.23.7 6.86.75.04.43.83.63.6

As shown in Table 6a, the dandelion granule tea of the control group is clear and yellow, but becomes opaque as the amount of the extract added to the extract, the color of the granule tea is changed to a dark brown color. In addition, the irritating irritant smell and astringent taste were increased, the taste and overall preference tended to decrease. However, in the experimental groups 1-1 to 1-4, there was no significant decrease overall.

Sensory Evaluation of Dandelion Granulated Tea Added with Ginseng Extract Experimental group Color flavor General Symbol Control group 2-2 Experiment group 2-4 Experiment group 2-6 Experiment group 2-8 Experiment group 2-10 Experiment group 2-12 6.67.07.15.04.94.74.6 6.67.87.05.34.64.24.0 6.87.77.15.54.84.64.0

As shown in Table 6b, even when the added amount of the extract was increased, the color was changed, but unlike when the extract was added, turbidity was not increased, only the color was changed to dark brown. . In addition, when the added amount of the extract was increased, the irritating smell was increased, but unlike when the extract was added, the astringent taste did not increase, the taste and overall preference tended to decrease slowly. However, for the experimental groups 2-1 to 2-4, there was no significant decrease overall.

Sensory Test Results of Dandelion Granule Tea Added with Extracts of Morus alba L. Experimental group Color flavor General Symbol Control group 3-1 Experiment group 3-2 Experiment group 3-3 Experiment group 3-4 Experiment group 3-5 6.66.76.45.45.34.1 6.67.67.36.96.45.1 6.87.37.06.65.94.6

As shown in Table 6c, even when added to the extract extract and the extract of Ginseng, the same aspect as in Tables 6a and 6b.

However, it was found that the palatability of the dandelion granule tea of each experimental group including the control group was low, because the dandelion leaf's own fishy smell, grass smell, and slight burniness appeared.

Example 3-4 Preparation of Dandelion Granulated Tea Containing Dandelion Root Extract and Its Sensory Evaluation

In the above Example 3-3, as described above, the dandelion granulated tea including dandelion leaf extract, lettuce extract, glucose extract and glucose showed inherent fishy smell, grassy smell and slight burniness, and thus, dandelion root. To improve the palatability by the addition of the extract obtained in.

That is, a dandelion root extract of 60 ° Brix was obtained using the method described in Example 3-1, except that 1 kg of washed yellow dandelion roots were used. Subsequently, 100 parts by weight of glucose, 2 parts by weight of the extract of lettuce extract, 2 parts by weight of ginseng extract, and 15 parts by weight of the dandelion extract mixture of dandelion leaf extract and dandelion root extract were mixed to obtain a mixture, which was obtained at 45 ° C. Each dandelion granulated tea was prepared by hot air drying, and 30 g of each granulated tea was dissolved in warm water at 70 ° C., and 20 sensory test personnel carried out a sensory test using a nine-point scoring method. At this time, the dandelion extract mixture of leaf extract and root extract 1: 1 (experimental group a), 2: 1 (experimental group b), 3: 1 (experimental group c), 4: 1 (experimental group d) and 5: 1 (experimental group), respectively. e) a mixture of (w / w) was used, and as a control, a granular tea was used without adding the dandelion mixture (see Table 7a).

Sensory Test Results of Dandelion Granule Tea with Mixture Ratio of Dandelion Extract Mixtures Experimental group Color flavor General Symbol Control group a Experiment group b Experiment group c Experiment group d Experiment group e 1.64.75.07.67.16.8 1.64.64.87.76.86.1 1.84.66.17.96.96.6

As shown in Table 7a, the mixing ratio of the dandelion leaf extract and the dandelion root extract was found to be the most excellent sensory properties when the 3: 1 (experimental group c) (w / w).

Subsequently, the addition amount of the dandelion extract mixture mixed at the selected ratio was varied to determine the composition of the dandelion granule tea showing the best sensory properties. That is, in the mixture of 100 parts by weight of glucose, 2 parts by weight of the extract of the lettuce extract, and 2 parts by weight of the ginseng extract, 10 parts by weight of the dandelion mixture each having a dandelion leaf extract and a root extract of 3: 1 (w / w) Experimental group f), 12 parts by weight (experimental group g), 14 parts by weight (experimental group h), 16 parts by weight (experimental group i), 18 parts by weight (experimental group j) and 20 parts by weight (experimental group k) were added, which was 45 ° C. Each dandelion granule tea was prepared by hot air drying at 200 mg, and 200 mg of each granulated tea was dissolved in 100 ml of hot water at 70 ° C., and 20 sensory test personnel performed sensory tests using a nine-point scoring method. At this time, as a control, a granular tea was used without adding the dandelion mixture (see Table 7b).

Sensory Test Results of Dandelion Granulated Tea by Contents of Dandelion Mixture Experimental group Color flavor General Symbol Control group Experiment group f Experiment group g Experiment group h Experiment group i Experiment group j Experiment group k 1.65.77.08.48.47.16.9 1.65.68.29.78.77.16.9 1.85.68.18.98.47.16.8

As shown in Table 7b, when the dandelion extract mixture of the dandelion leaf extract and the root extract is mixed 3: 1 (w / w) is added to 12 parts by weight to 16 parts by weight, it can be seen that the sensory properties are the best there was.

Therefore, when the results of Tables 7a and 7b were combined, it was found that the content of the dandelion leaf extract showing the best sensory properties was 9 to 12 parts by weight, and the content of the dandelion root extract was 3 to 4 parts by weight.

Based on the above results, dandelion granule tea having an effect of preventing dementia is 100 parts by weight of saccharides, 9 to 12 parts by weight of dandelion leaf extract, 3 to 4 parts by weight of dandelion root extract, 2 to 4 parts by weight of lettuce extract and sugar extract 2 To 4 parts by weight was confirmed to include.

As described and demonstrated in detail above, the present invention provides a dandelion granule tea comprising the dandelion leaf extract, dandelion root extract, lettuce extract and sugar extract and a method for producing the same. Dandelion granule tea of the present invention is not only excellent dementia prevention effect, but also excellent palatability, it can be widely used as a functional food for preventing dementia.

Claims (2)

(Iii) 100 parts by weight of glucose, 9 to 12 parts by weight of dandelion leaf hot water extract of 50 to 70 Brix, 3 to 4 parts by weight of dandelion root hot water extract of 50 to 70 Brix, 2 to 4 parts by weight of hot water extract of 50 to 70 Brix Mixing 2 to 4 parts by weight of the sugar ginseng hot water extract of 70-Brix; (Ii) concentrating and granulating the mixture to obtain granules; And, (Iii) A method for producing a dandelion granule tea, comprising the step of drying the granules obtained previously. Prepared by the method of claim 1, comprising 100 parts by weight of sugar, 9 to 12 parts by weight of dandelion leaf extract, 3 to 4 parts by weight of dandelion root extract, 2 to 4 parts by weight of lettuce extract and 2 to 4 parts by weight of sugar extract, dementia Dandelion granulated tea with a protective effect.