KR100504322B1 - Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof - Google Patents

Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof

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Publication number
KR100504322B1
KR100504322B1 KR10-2004-0060593A KR20040060593A KR100504322B1 KR 100504322 B1 KR100504322 B1 KR 100504322B1 KR 20040060593 A KR20040060593 A KR 20040060593A KR 100504322 B1 KR100504322 B1 KR 100504322B1
Authority
KR
South Korea
Prior art keywords
alphavirus
preparation
expression vectors
tumor suppressor
based expression
Prior art date
Application number
KR10-2004-0060593A
Other languages
English (en)
Other versions
KR20040077600A (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to KR10-2004-0060593A priority Critical patent/KR100504322B1/ko
Publication of KR20040077600A publication Critical patent/KR20040077600A/ko
Application granted granted Critical
Publication of KR100504322B1 publication Critical patent/KR100504322B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR10-2004-0060593A 2004-07-30 2004-07-30 Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof KR100504322B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR10-2004-0060593A KR100504322B1 (en) 2004-07-30 2004-07-30 Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR10-2004-0060593A KR100504322B1 (en) 2004-07-30 2004-07-30 Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR10-2001-0008201A Division KR100457791B1 (ko) 2001-02-19 2001-02-19 암억제 단백질을 발현하는 알파바이러스계 발현 벡터, 이의 제조 방법 및 용도

Publications (2)

Publication Number Publication Date
KR20040077600A KR20040077600A (ko) 2004-09-04
KR100504322B1 true KR100504322B1 (en) 2005-07-28

Family

ID=37363355

Family Applications (1)

Application Number Title Priority Date Filing Date
KR10-2004-0060593A KR100504322B1 (en) 2004-07-30 2004-07-30 Alphavirus-based expression vectors expressing tumor suppressor proteins, the preparation and the use thereof

Country Status (1)

Country Link
KR (1) KR100504322B1 (ko)

Also Published As

Publication number Publication date
KR20040077600A (ko) 2004-09-04

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