JPWO2023145812A1 - - Google Patents

Info

Publication number
JPWO2023145812A1
JPWO2023145812A1 JP2023576973A JP2023576973A JPWO2023145812A1 JP WO2023145812 A1 JPWO2023145812 A1 JP WO2023145812A1 JP 2023576973 A JP2023576973 A JP 2023576973A JP 2023576973 A JP2023576973 A JP 2023576973A JP WO2023145812 A1 JPWO2023145812 A1 JP WO2023145812A1
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023576973A
Other languages
Japanese (ja)
Other versions
JPWO2023145812A5 (https=
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPWO2023145812A1 publication Critical patent/JPWO2023145812A1/ja
Publication of JPWO2023145812A5 publication Critical patent/JPWO2023145812A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2023576973A 2022-01-31 2023-01-26 Pending JPWO2023145812A1 (https=)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022013048 2022-01-31
PCT/JP2023/002409 WO2023145812A1 (ja) 2022-01-31 2023-01-26 グルコセレブロシダーゼ活性を有する糖鎖付加タンパク質

Publications (2)

Publication Number Publication Date
JPWO2023145812A1 true JPWO2023145812A1 (https=) 2023-08-03
JPWO2023145812A5 JPWO2023145812A5 (https=) 2024-09-26

Family

ID=87471497

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023576973A Pending JPWO2023145812A1 (https=) 2022-01-31 2023-01-26

Country Status (3)

Country Link
US (1) US20250145978A1 (https=)
JP (1) JPWO2023145812A1 (https=)
WO (1) WO2023145812A1 (https=)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008431A1 (en) * 2001-06-19 2003-01-30 Otsuka Chemical Co.,Ltd. Process for producing sugar chain asparagine derivative
WO2005010053A1 (ja) * 2003-07-28 2005-02-03 Otsuka Chemical Co., Ltd. アミノ化複合型糖鎖誘導体及びその製造方法
JP2014500722A (ja) * 2010-11-08 2014-01-16 カリダス・バイオファーマ,インコーポレーテッド 増加した安定性および増加した保持触媒活性を有する変異型組換えβ−グルコセレブロシダーゼタンパク質
WO2014157107A1 (ja) * 2013-03-29 2014-10-02 株式会社糖鎖工学研究所 シアリル化糖鎖が付加されたポリペプチド
WO2020157248A1 (en) * 2019-02-01 2020-08-06 Oxyrane Uk Ltd Glucocerebrosidase polypeptides
WO2021048034A1 (en) * 2019-09-09 2021-03-18 F. Hoffmann-La Roche Ag Glucocerebrosidase mutants
WO2021199039A1 (en) * 2020-03-29 2021-10-07 Yeda Research And Development Co. Ltd. Variants of beta-glucocerebrosidase for use in treating gaucher disease

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003008431A1 (en) * 2001-06-19 2003-01-30 Otsuka Chemical Co.,Ltd. Process for producing sugar chain asparagine derivative
WO2005010053A1 (ja) * 2003-07-28 2005-02-03 Otsuka Chemical Co., Ltd. アミノ化複合型糖鎖誘導体及びその製造方法
JP2014500722A (ja) * 2010-11-08 2014-01-16 カリダス・バイオファーマ,インコーポレーテッド 増加した安定性および増加した保持触媒活性を有する変異型組換えβ−グルコセレブロシダーゼタンパク質
WO2014157107A1 (ja) * 2013-03-29 2014-10-02 株式会社糖鎖工学研究所 シアリル化糖鎖が付加されたポリペプチド
WO2020157248A1 (en) * 2019-02-01 2020-08-06 Oxyrane Uk Ltd Glucocerebrosidase polypeptides
WO2021048034A1 (en) * 2019-09-09 2021-03-18 F. Hoffmann-La Roche Ag Glucocerebrosidase mutants
WO2021199039A1 (en) * 2020-03-29 2021-10-07 Yeda Research And Development Co. Ltd. Variants of beta-glucocerebrosidase for use in treating gaucher disease

Also Published As

Publication number Publication date
WO2023145812A1 (ja) 2023-08-03
US20250145978A1 (en) 2025-05-08

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