JPWO2023027041A1 - - Google Patents
Info
- Publication number
- JPWO2023027041A1 JPWO2023027041A1 JP2023543913A JP2023543913A JPWO2023027041A1 JP WO2023027041 A1 JPWO2023027041 A1 JP WO2023027041A1 JP 2023543913 A JP2023543913 A JP 2023543913A JP 2023543913 A JP2023543913 A JP 2023543913A JP WO2023027041 A1 JPWO2023027041 A1 JP WO2023027041A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021135502 | 2021-08-23 | ||
| PCT/JP2022/031615 WO2023027041A1 (ja) | 2021-08-23 | 2022-08-22 | 部位特異的ヌクレアーゼ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023027041A1 true JPWO2023027041A1 (https=) | 2023-03-02 |
| JPWO2023027041A5 JPWO2023027041A5 (https=) | 2025-06-03 |
Family
ID=85323220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023543913A Pending JPWO2023027041A1 (https=) | 2021-08-23 | 2022-08-22 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240352436A1 (https=) |
| EP (1) | EP4394037A4 (https=) |
| JP (1) | JPWO2023027041A1 (https=) |
| WO (1) | WO2023027041A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113811608B (zh) | 2019-02-22 | 2024-10-29 | 合成Dna技术公司 | 毛螺菌科细菌nd2006 cas12a突变型基因和由其编码的多肽 |
| CN116096878A (zh) | 2020-05-01 | 2023-05-09 | 合成Dna技术公司 | 在非经典tttt前间区序列邻近基序处具有增强的切割活性的毛螺菌科菌种cas12a突变体 |
| US20240368571A1 (en) * | 2023-04-28 | 2024-11-07 | Integrated Dna Technologies, Inc. | Eubacterium rectale cas12a mutants |
| WO2025038872A1 (en) * | 2023-08-15 | 2025-02-20 | Bio-Techne Corporation | Compositions and methods related to crispr-associated enzymes |
| CN119264278B (zh) * | 2024-12-09 | 2025-04-11 | 中国水产科学研究院南海水产研究所 | 一种用于斑节对虾基因编辑的融合蛋白PmMAD7-NLS及其应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019504649A (ja) * | 2016-02-15 | 2019-02-21 | ベンソン ヒル バイオシステムズ，インコーポレイティド | ゲノムを改変するための組成物及び方法 |
| WO2021074191A1 (en) * | 2019-10-14 | 2021-04-22 | KWS SAAT SE & Co. KGaA | Mad7 nuclease in plants and expanding its pam recognition capability |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020086475A1 (en) * | 2018-10-22 | 2020-04-30 | Inscripta, Inc. | Engineered enzymes |
| EP4165180A4 (en) * | 2020-06-16 | 2024-10-23 | Bio-Techne Corporation | MODIFIED MAD7-DIRECTED ENDONUCLEASE |
| JP7113415B1 (ja) | 2022-01-28 | 2022-08-05 | 株式会社セツロテック | 変異型ｍａｄ７タンパク質 |
-
2022
- 2022-08-22 US US18/685,710 patent/US20240352436A1/en active Pending
- 2022-08-22 WO PCT/JP2022/031615 patent/WO2023027041A1/ja not_active Ceased
- 2022-08-22 EP EP22861329.5A patent/EP4394037A4/en active Pending
- 2022-08-22 JP JP2023543913A patent/JPWO2023027041A1/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019504649A (ja) * | 2016-02-15 | 2019-02-21 | ベンソン ヒル バイオシステムズ，インコーポレイティド | ゲノムを改変するための組成物及び方法 |
| WO2021074191A1 (en) * | 2019-10-14 | 2021-04-22 | KWS SAAT SE & Co. KGaA | Mad7 nuclease in plants and expanding its pam recognition capability |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4394037A4 (en) | 2026-01-28 |
| WO2023027041A1 (ja) | 2023-03-02 |
| US20240352436A1 (en) | 2024-10-24 |
| EP4394037A1 (en) | 2024-07-03 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
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| A521 | Request for written amendment filed |
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