JPWO2023010073A5 - - Google Patents

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Publication number
JPWO2023010073A5
JPWO2023010073A5 JP2024505066A JP2024505066A JPWO2023010073A5 JP WO2023010073 A5 JPWO2023010073 A5 JP WO2023010073A5 JP 2024505066 A JP2024505066 A JP 2024505066A JP 2024505066 A JP2024505066 A JP 2024505066A JP WO2023010073 A5 JPWO2023010073 A5 JP WO2023010073A5
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JP
Japan
Prior art keywords
cells
cell
engineered
receptor
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024505066A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024527997A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/074251 external-priority patent/WO2023010073A1/en
Publication of JP2024527997A publication Critical patent/JP2024527997A/ja
Publication of JPWO2023010073A5 publication Critical patent/JPWO2023010073A5/ja
Pending legal-status Critical Current

Links

JP2024505066A 2021-07-28 2022-07-28 T細胞持続性及び機能を改善するための組成物及び方法 Pending JP2024527997A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163226559P 2021-07-28 2021-07-28
US63/226,559 2021-07-28
PCT/US2022/074251 WO2023010073A1 (en) 2021-07-28 2022-07-28 Compositions and methods for improving t cell persistence and function

Publications (2)

Publication Number Publication Date
JP2024527997A JP2024527997A (ja) 2024-07-26
JPWO2023010073A5 true JPWO2023010073A5 (enExample) 2025-08-04

Family

ID=85087331

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024505066A Pending JP2024527997A (ja) 2021-07-28 2022-07-28 T細胞持続性及び機能を改善するための組成物及び方法

Country Status (5)

Country Link
US (1) US20240327826A1 (enExample)
EP (1) EP4376858A4 (enExample)
JP (1) JP2024527997A (enExample)
CN (1) CN117813102A (enExample)
WO (1) WO2023010073A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024173916A1 (en) * 2023-02-17 2024-08-22 Dana-Farber Cancer Institute, Inc. Compositions and methods of preventing t cell exhaustion
CN118345080B (zh) * 2024-06-17 2024-09-24 江苏柯菲平医药股份有限公司 一种抗耗竭t细胞及其制备方法、应用
CN119120385B (zh) * 2024-11-14 2025-03-14 四川大学华西医院 一种具有长效抑瘤效果的嵌合抗原受体t细胞及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3701039A4 (en) * 2017-10-27 2021-11-17 The Trustees of The University of Pennsylvania IDENTIFICATION OF EPIGENETIC AND TRANSCRIPT TARGETS TO PREVENT AND REVERSE T-LYMPHOCYTE DEPLETION
MX2020006015A (es) * 2017-12-15 2020-10-12 Univ Leland Stanford Junior Composiciones y procedimientos para inhibir el agotamiento de celulas t.
CN118325839A (zh) * 2018-03-27 2024-07-12 宾夕法尼亚大学董事会 具有增强功能的修饰的免疫细胞及其筛选方法
CN110904045A (zh) * 2018-09-17 2020-03-24 中国科学院动物研究所 经修饰的t细胞、其制备方法及用途
US20220354889A1 (en) * 2019-03-26 2022-11-10 The Trustees Of The University Of Pennsylvania Dnmt3a knockout car t cells for adoptive immunotherapy
US20220226380A1 (en) * 2019-04-24 2022-07-21 St. Jude Children's Research Hospital, Inc. Gene knock-outs to improve t cell function

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