JPWO2022204670A5 - - Google Patents
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- Publication number
- JPWO2022204670A5 JPWO2022204670A5 JP2023558125A JP2023558125A JPWO2022204670A5 JP WO2022204670 A5 JPWO2022204670 A5 JP WO2022204670A5 JP 2023558125 A JP2023558125 A JP 2023558125A JP 2023558125 A JP2023558125 A JP 2023558125A JP WO2022204670 A5 JPWO2022204670 A5 JP WO2022204670A5
- Authority
- JP
- Japan
- Prior art keywords
- aav
- capsid
- itr
- chromatography
- capsids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163164206P | 2021-03-22 | 2021-03-22 | |
| US63/164,206 | 2021-03-22 | ||
| PCT/US2022/071245 WO2022204670A2 (en) | 2021-03-22 | 2022-03-21 | Size exclusion chromatography analysis of empty and full aav capsids |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024511409A JP2024511409A (ja) | 2024-03-13 |
| JP2024511409A5 JP2024511409A5 (https=) | 2025-04-14 |
| JPWO2022204670A5 true JPWO2022204670A5 (https=) | 2025-04-14 |
Family
ID=81580107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023558125A Pending JP2024511409A (ja) | 2021-03-22 | 2022-03-21 | 空および完全ａａｖキャプシドのサイズ排除クロマトグラフィー解析 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240159718A1 (https=) |
| EP (1) | EP4314303A2 (https=) |
| JP (1) | JP2024511409A (https=) |
| CN (1) | CN117460832A (https=) |
| WO (1) | WO2022204670A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240210385A1 (en) * | 2022-12-22 | 2024-06-27 | Lonza Houston, Inc. | Methods for characterizing lentiviruses |
| US12434218B2 (en) | 2023-11-28 | 2025-10-07 | Phenomenex, Inc. | Pore structure for separation of adeno-associated viruses (AAVS) from their aggregates |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5622856A (en) | 1995-08-03 | 1997-04-22 | Avigen | High efficiency helper system for AAV vector production |
| US6027931A (en) | 1995-08-03 | 2000-02-22 | Avigen, Inc. | High-efficiency AA V helper functions |
| US6001650A (en) | 1995-08-03 | 1999-12-14 | Avigen, Inc. | High-efficiency wild-type-free AAV helper functions |
| US6995006B2 (en) | 1997-09-05 | 2006-02-07 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| PT1916258E (pt) | 1999-08-09 | 2014-07-29 | Genzyme Corp | Aumento da expressão de uma sequência nucleotídica heteróloga de cadeia simples a partir de vectores virais recombinantes por concepção da sequência de maneira que esta forme pares de bases intracadeia |
| NZ522840A (en) | 2000-06-01 | 2004-12-24 | Univ North Carolina | A parvovirus vector that carries a duplexed genome resulting in co-packaging of strands of plus and minus polarity tethered together |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| NZ532635A (en) | 2001-11-13 | 2007-05-31 | Univ Pennsylvania | A method of identifying unknown adeno-associated virus (AAV) sequences and a kit for the method |
| DE602004030327D1 (de) | 2003-05-21 | 2011-01-13 | Genzyme Corp | Verfahren zur herstellung von präparationen rekombinanter aav-virionen, die weitgehend frei von leeren capsiden sind |
| US20050101025A1 (en) * | 2003-11-12 | 2005-05-12 | Ho Winston Z. | Apparatus for proteins and nucleic acids analysis |
| US7765583B2 (en) | 2005-02-28 | 2010-07-27 | France Telecom | System and method for managing virtual user domains |
| US8283151B2 (en) | 2005-04-29 | 2012-10-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes |
| HUE028341T2 (en) | 2009-06-16 | 2016-12-28 | Genzyme Corp | Improved methods for purification of recombinant aav vectors |
| CA3301261A1 (en) | 2015-01-20 | 2026-03-02 | Genzyme Corporation | Analytical ultracentrifugation for characterization of recombinant viral particles |
| WO2019212922A1 (en) * | 2018-04-29 | 2019-11-07 | Regenxbio Inc. | Systems and methods of spectrophotometry for the determination of genome content, capsid content and full/empty ratios of adeno-associated virus particles |
-
2022
- 2022-03-21 CN CN202280022754.XA patent/CN117460832A/zh active Pending
- 2022-03-21 EP EP22721240.4A patent/EP4314303A2/en active Pending
- 2022-03-21 WO PCT/US2022/071245 patent/WO2022204670A2/en not_active Ceased
- 2022-03-21 US US18/282,739 patent/US20240159718A1/en active Pending
- 2022-03-21 JP JP2023558125A patent/JP2024511409A/ja active Pending
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