JPWO2022163466A1 - - Google Patents

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Publication number
JPWO2022163466A1
JPWO2022163466A1 JP2022578285A JP2022578285A JPWO2022163466A1 JP WO2022163466 A1 JPWO2022163466 A1 JP WO2022163466A1 JP 2022578285 A JP2022578285 A JP 2022578285A JP 2022578285 A JP2022578285 A JP 2022578285A JP WO2022163466 A1 JPWO2022163466 A1 JP WO2022163466A1
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Japan
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JP2022578285A
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JPWO2022163466A5 (https=
JP7536245B2 (ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/145—Thrombopoietin [TPO]
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2302—Interleukin-2 (IL-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2303—Interleukin-3 (IL-3)
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2306—Interleukin-6 (IL-6)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/606—Transcription factors c-Myc
    • C—CHEMISTRY; METALLURGY
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/08—Coculture with; Conditioned medium produced by cells of the nervous system
    • C12N2502/086—Coculture with; Conditioned medium produced by cells of the nervous system glial cells
    • C—CHEMISTRY; METALLURGY
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2022578285A 2021-01-26 2022-01-19 オリゴデンドロサイトの作製方法 Active JP7536245B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163141626P 2021-01-26 2021-01-26
US63/141,626 2021-01-26
PCT/JP2022/001814 WO2022163466A1 (ja) 2021-01-26 2022-01-19 オリゴデンドロサイトの作製方法

Publications (3)

Publication Number Publication Date
JPWO2022163466A1 true JPWO2022163466A1 (https=) 2022-08-04
JPWO2022163466A5 JPWO2022163466A5 (https=) 2023-06-08
JP7536245B2 JP7536245B2 (ja) 2024-08-20

Family

ID=82653355

Family Applications (1)

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JP2022578285A Active JP7536245B2 (ja) 2021-01-26 2022-01-19 オリゴデンドロサイトの作製方法

Country Status (3)

Country Link
US (1) US20240093146A1 (https=)
JP (1) JP7536245B2 (https=)
WO (1) WO2022163466A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7844284B2 (ja) * 2022-08-12 2026-04-13 シーシーアイホールディングス株式会社 リソソーム局在性鉄イオンキレート化剤、リソソーム局在性フェロトーシス阻害剤、抗酸化剤細胞保護方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007069666A1 (ja) * 2005-12-13 2007-06-21 Kyoto University 核初期化因子
US20190322981A1 (en) * 2016-07-05 2019-10-24 Westfaelische Wilhelms-Universitaet Muenster Means and methods for the generation of oligodendrocytes
JP2020501533A (ja) * 2016-11-24 2020-01-23 ケンブリッジ エンタープライズ リミテド 制御可能な転写

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007069666A1 (ja) * 2005-12-13 2007-06-21 Kyoto University 核初期化因子
US20190322981A1 (en) * 2016-07-05 2019-10-24 Westfaelische Wilhelms-Universitaet Muenster Means and methods for the generation of oligodendrocytes
JP2020501533A (ja) * 2016-11-24 2020-01-23 ケンブリッジ エンタープライズ リミテド 制御可能な転写

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHANOUMIDOU K. ET AL.: "One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX", STEM CELL REPORTS, vol. 16, no. 4, JPN6022013393, 13 April 2021 (2021-04-13), pages 771 - 783, ISSN: 0005362235 *
EHRLICH M. ET AL.: "Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using t", PROC NATL ACAD SCI U S A, JPN6022013392, 28 February 2017 (2017-02-28), pages 2243 - 2252, ISSN: 0005252478 *
PAWLOWSKI M. ET AL.: "Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skelet", STEM CELL REPORTS, vol. 8, no. 4, JPN6022013391, 11 April 2017 (2017-04-11), pages 803 - 812, ISSN: 0005252477 *

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Publication number Publication date
WO2022163466A1 (ja) 2022-08-04
US20240093146A1 (en) 2024-03-21
JP7536245B2 (ja) 2024-08-20

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