JPWO2021222625A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2021222625A5 JPWO2021222625A5 JP2022566130A JP2022566130A JPWO2021222625A5 JP WO2021222625 A5 JPWO2021222625 A5 JP WO2021222625A5 JP 2022566130 A JP2022566130 A JP 2022566130A JP 2022566130 A JP2022566130 A JP 2022566130A JP WO2021222625 A5 JPWO2021222625 A5 JP WO2021222625A5
- Authority
- JP
- Japan
- Prior art keywords
- user
- phase
- nicotine
- determining
- program
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000090 biomarker Substances 0.000 claims 20
- 238000001514 detection method Methods 0.000 claims 16
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 claims 14
- 229960002715 nicotine Drugs 0.000 claims 14
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 claims 14
- 235000019504 cigarettes Nutrition 0.000 claims 13
- 206010057852 Nicotine dependence Diseases 0.000 claims 10
- 230000004048 modification Effects 0.000 claims 10
- 238000012986 modification Methods 0.000 claims 10
- 230000000391 smoking effect Effects 0.000 claims 10
- 238000002670 nicotine replacement therapy Methods 0.000 claims 7
- 231100000430 skin reaction Toxicity 0.000 claims 5
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 claims 4
- 229910002091 carbon monoxide Inorganic materials 0.000 claims 4
- 230000009467 reduction Effects 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 3
- 239000003550 marker Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000003542 behavioural effect Effects 0.000 claims 2
- 235000019788 craving Nutrition 0.000 claims 2
- 230000009471 action Effects 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 230000006399 behavior Effects 0.000 claims 1
- 238000013542 behavioral therapy Methods 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 claims 1
- 230000008859 change Effects 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 230000029058 respiratory gaseous exchange Effects 0.000 claims 1
- 230000000284 resting effect Effects 0.000 claims 1
- 230000006641 stabilisation Effects 0.000 claims 1
- 238000011105 stabilization Methods 0.000 claims 1
Claims (23)
プロセッサを備え、前記プロセッサが、
ユーザの停止プログラムを決定し、
前記停止プログラムのフェーズ及び前記ユーザに関連付けられたマーカーに基づいて、プログラム介入イベントを決定し、
前記プログラム介入イベントに基づいて、前記停止プログラムに対する修正を決定するように構成されている、デバイス。 1. A device for providing nicotine replacement therapy, comprising:
a processor, the processor comprising:
Determine the user's stop program;
determining a program intervention event based on a phase of the stopped program and a marker associated with the user;
A device configured to determine a modification to the stopped program based on the program intervention event.
前記ユーザのニコチン製剤消費率を決定すること、
前記ユーザの一酸化炭素飽和レベルを決定すること、並びに
前記ユーザの前記シガレット消費率、前記ニコチン製剤消費率、及び前記一酸化炭素飽和レベルに基づいて、前記プログラム介入イベントを決定すること、
によって、前記停止プログラムの前記フェーズ及び前記ユーザの前記シガレット消費率に基づく前記プログラム介入イベントを決定するように構成されている、請求項1に記載のデバイス。 the marker is a cigarette consumption rate of the user, and the processor:
determining a rate of consumption of a nicotine formulation of said user;
determining a carbon monoxide saturation level of the user; and determining the program intervention event based on the user's cigarette consumption rate, the nicotine formulation consumption rate, and the carbon monoxide saturation level.
2. The device of claim 1 , configured to determine the program intervention event based on the phase of the suspension program and the cigarette consumption rate of the user by:
前記プログラム介入イベントによって示される停止傾向を決定すること、及び
前記停止傾向に基づいて前記停止プログラムの前記フェーズの持続時間を変更すること、
によって、前記プログラム介入イベントに基づく前記停止プログラムに対する前記修正を決定するように構成されている、請求項7に記載のデバイス。 The processor,
determining a propensity to stop being stopped indicated by the program intervention event; and modifying a duration of the phase of the stopping program based on the propensity to stop being stopped.
The device of claim 7 , configured to determine the modification to the stopped program based on the program intervention event by:
プロセッサを備え、前記プロセッサが、
ユーザに関連付けられたバイオマーカーを決定し、
前記ユーザに関連付けられた前記バイオマーカーを使用して、ニコチン渇望を検出し、
前記ニコチン渇望に基づいて、前記ユーザに介入を提供するように構成されている、デバイス。 1. A device for providing nicotine replacement therapy, comprising:
a processor, the processor comprising:
determining biomarkers associated with the user;
detecting nicotine craving using the biomarker associated with the user;
The device is configured to provide an intervention to the user based on the nicotine craving.
前記ユーザに関連付けられた第2のバイオマーカーを決定すること、
前記第1のバイオマーカー及び前記第2のバイオマーカーに基づく予測値を計算することであって、前記予測値は、前記ユーザがニコチンの渇望を経験している確率を示す、計算すること、並びに
前記予測値が閾値を超過したときに、前記ユーザが前記ニコチン渇望を経験していると決定すること、
によって、前記ユーザに関連付けられた前記第1のバイオマーカーを使用して前記ニコチン渇望を検出するように構成されている、請求項9に記載のデバイス。 the biomarker is a first biomarker, and the processor:
determining a second biomarker associated with the user;
calculating a predictive value based on the first biomarker and the second biomarker, the predictive value indicating a probability that the user is experiencing nicotine craving; and determining that the user is experiencing nicotine craving when the predictive value exceeds a threshold.
10. The device of claim 9, configured to detect the nicotine craving using the first biomarker associated with the user by:
前記ユーザの心拍数を決定すること、
前記ユーザの皮膚温度を決定すること、並びに
前記ガルバニック皮膚反応、前記心拍数、及び前記皮膚温度を使用して前記ニコチン渇望を検出すること、
によって、前記ユーザに関連付けられた前記ガルバニック皮膚反応を使用して前記ニコチン渇望を検出するように構成されている、請求項9に記載のデバイス。 the biomarker is a galvanic skin response associated with the user, and the processor:
determining a heart rate of the user;
determining a skin temperature of the user; and detecting the nicotine craving using the galvanic skin response, the heart rate, and the skin temperature.
10. The device of claim 9, configured to detect the nicotine craving using the galvanic skin response associated with the user by
前記ユーザに関連付けられた停止プログラムのフェーズを決定し、
前記ニコチン渇望及び前記停止プログラムの前記フェーズに基づいて、前記ユーザに前記介入を提供するように更に構成されている、請求項9に記載のデバイス。 The processor,
determining a phase of a stop program associated with the user;
10. The device of claim 9, further configured to provide the intervention to the user based on the nicotine craving and the phase of the cessation program.
前記介入、前記フェーズ、及び前記バイオマーカーによって示される停止傾向を決定し、
前記停止傾向に基づいて、前記フェーズの持続時間を変更するように更に構成されている、請求項12に記載のデバイス。 The processor,
determining the intervention, the phase, and a propensity to stop as indicated by the biomarkers;
The device of claim 12 , further configured to vary a duration of the phase based on the stopping tendency.
プロセッサを備え、前記プロセッサが、
ユーザに関連付けられた停止プログラムのフェーズを決定し、
前記ユーザに関連付けられたバイオマーカーに基づいて、喫煙検出イベントを決定し、
前記フェーズ及び前記喫煙検出イベントに基づいて、前記停止プログラムに対する修正を決定するように構成されている、デバイス。 1. A device for providing nicotine replacement therapy, comprising:
a processor, the processor comprising:
determining a phase of a suspension program associated with the user;
determining a smoking detection event based on a biomarker associated with the user;
The device is configured to determine modifications to the suspension program based on the phase and the smoking detection event.
前記喫煙検出イベントを使用して、前記ユーザのシガレット消費率を決定すること、
前記シガレット消費率に基づいて、前記第1のフェーズの持続時間に対する増加を決定すること、
前記第1のフェーズの前記持続時間に対する前記増加が閾値を超過することになると決定すること、及び
前記ユーザを前記停止プログラムの第2のフェーズに割り当てること、
によって、前記第1のフェーズ及び前記喫煙検出イベントに基づく前記停止プログラムの前記修正を決定するように構成されている、請求項16に記載のデバイス。 the phase is a first phase, the processor
using the smoking detection events to determine a cigarette consumption rate of the user;
determining an increase to the duration of the first phase based on the rate of cigarette consumption;
determining that the increase to the duration of the first phase will exceed a threshold; and assigning the user to a second phase of the suspension program.
17. The device of claim 16, configured to determine the modification of the stopping program based on the first phase and the smoking detection event by:
前記バイオマーカー傾向が前記閾値を超過したと決定されたときに、前記ユーザを前記停止プログラムの第2のフェーズに割り当てること、
前記喫煙検出イベントを使用して、シガレット消費率を決定すること、及び
前記シガレット消費率に基づいて、前記停止プログラムの前記第2のフェーズの持続時間を決定すること、
によって、前記第1のフェーズ及び前記喫煙検出イベントに基づく前記停止プログラムの前記修正を決定するように構成されている、請求項19に記載のデバイス。 the phase is a first phase, the processor
assigning the user to a second phase of the stopping program when the biomarker trend is determined to have exceeded the threshold;
determining a cigarette consumption rate using the smoking detection event; and determining a duration of the second phase of the suspension program based on the cigarette consumption rate.
20. The device of claim 19, configured to determine the modification of the stopping program based on the first phase and the smoking detection event by:
前記バイオマーカー傾向が前記閾値を超過したと決定されたときに、前記喫煙検出イベントを使用して、シガレット消費率を決定すること、及び
前記シガレット消費率に基づいて、前記停止プログラムの前記フェーズの持続時間を決定すること、
によって、前記フェーズ及び前記喫煙検出イベントに基づく前記停止プログラムに対する前記修正を決定するように構成されている、請求項19に記載のデバイス。 The processor,
determining a cigarette consumption rate using the smoking detection event when the biomarker trend is determined to exceed the threshold; and determining a duration of the phase of the cessation program based on the cigarette consumption rate.
20. The device of claim 19, configured to determine the modifications to the stopping program based on the phase and the smoking detection event by:
プロセッサを備え、前記プロセッサが、
ユーザに関連付けられた停止プログラムのフェーズを決定し、
ニコチン消費検出イベントを決定し、
前記フェーズ及び前記ニコチン消費検出イベントに基づいて、前記停止プログラムに対する修正を決定するように構成されている、デバイス。 1. A device for providing nicotine replacement therapy, comprising:
a processor, the processor comprising:
determining a phase of a suspension program associated with the user;
determining a nicotine consumption detection event;
The device is configured to determine modifications to the cessation program based on the phase and the nicotine consumption detection event.
ニコチン消費が前記ユーザのニコチン閾値を下回ると決定されたときに、前記ユーザを前記停止プログラムの第2のフェーズに割り当てること、
前記ニコチン消費検出イベントを使用して、ニコチン消費率を決定すること、及び
前記ニコチン消費率に基づいて、前記停止プログラムの前記第2のフェーズの持続時間を決定すること、
によって、前記第1のフェーズ及び前記ニコチン消費に基づく前記停止プログラムの前記修正を決定するように構成されている、請求項22に記載のデバイス。 the phase is a first phase , the processor
assigning the user to a second phase of the cessation program when nicotine consumption is determined to be below the user's nicotine threshold;
determining a rate of nicotine consumption using the nicotine consumption detection event; and determining a duration of the second phase of the cessation program based on the rate of nicotine consumption.
23. The device of claim 22, configured to determine the modification of the cessation program based on the first phase and the nicotine consumption by:
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063018035P | 2020-04-30 | 2020-04-30 | |
US63/018,035 | 2020-04-30 | ||
PCT/US2021/029969 WO2021222625A1 (en) | 2020-04-30 | 2021-04-29 | Biomarker based nicotine replacement therapy |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2023524691A JP2023524691A (en) | 2023-06-13 |
JPWO2021222625A5 true JPWO2021222625A5 (en) | 2024-04-24 |
Family
ID=76035141
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2022566130A Pending JP2023524691A (en) | 2020-04-30 | 2021-04-29 | Biomarker-based nicotine replacement therapy |
JP2022566090A Pending JP2023524689A (en) | 2020-04-30 | 2021-04-29 | nicotine replacement therapy smart device |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2022566090A Pending JP2023524689A (en) | 2020-04-30 | 2021-04-29 | nicotine replacement therapy smart device |
Country Status (11)
Country | Link |
---|---|
US (2) | US20210337881A1 (en) |
EP (2) | EP4143837A2 (en) |
JP (2) | JP2023524691A (en) |
KR (2) | KR20230006882A (en) |
CN (2) | CN115485781A (en) |
AU (2) | AU2021263458A1 (en) |
BR (2) | BR112022021887A2 (en) |
CA (2) | CA3181602A1 (en) |
IL (2) | IL297673A (en) |
MX (2) | MX2022013639A (en) |
WO (2) | WO2021222617A2 (en) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6223744B1 (en) * | 1999-03-16 | 2001-05-01 | Multi-Vet Ltd. | Wearable aerosol delivery apparatus |
US20110182918A1 (en) * | 2008-06-13 | 2011-07-28 | Nabi Biopharmaceuticals | Personalized drug treatment and smoking cessation kit and method |
US20110182831A1 (en) * | 2010-01-25 | 2011-07-28 | Aradigm Corporation | Systems and methods used in conjunction with nicotine vaccines for effecting cessation of tobacco use |
US20120072231A1 (en) * | 2010-09-22 | 2012-03-22 | I.D. Therapeutics Llc | Methods, systems, and apparatus for optimizing effects of treatment with medication using medication compliance patterns |
WO2012154704A2 (en) * | 2011-05-06 | 2012-11-15 | Incube Labs, Llc | System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings |
US20180358117A1 (en) * | 2012-06-04 | 2018-12-13 | Pharmalto, Llc | System and Method for Personal Health Information Exchange |
CN105530916B (en) * | 2013-07-11 | 2020-04-07 | 艾利斯达医药品公司 | Nicotine salts with m-salicylic acid |
CA2977814A1 (en) * | 2015-03-12 | 2016-09-15 | Chrono Therapeutics Inc. | Craving input and support system |
US20180075219A1 (en) * | 2015-04-02 | 2018-03-15 | Click Therapeutics, Inc. | Therapeutic system and remote patient monitoring device |
CN113854979A (en) * | 2015-04-07 | 2021-12-31 | 凯洛特公司 | System and method for quantification and prediction of smoking behavior |
US10206572B1 (en) * | 2017-10-10 | 2019-02-19 | Carrot, Inc. | Systems and methods for quantification of, and prediction of smoking behavior |
EP3332322A4 (en) * | 2015-08-06 | 2018-08-22 | Avishai Abrahami | Cognitive state alteration system integrating multiple feedback technologies |
WO2018193592A1 (en) * | 2017-04-20 | 2018-10-25 | 株式会社キュア・アップ | Program, device, system, and method for patient attempting to quit smoking |
US11576435B2 (en) * | 2019-01-18 | 2023-02-14 | Hava Health, inc. | Smoking cessation system |
-
2021
- 2021-04-29 IL IL297673A patent/IL297673A/en unknown
- 2021-04-29 MX MX2022013639A patent/MX2022013639A/en unknown
- 2021-04-29 MX MX2022013640A patent/MX2022013640A/en unknown
- 2021-04-29 BR BR112022021887A patent/BR112022021887A2/en unknown
- 2021-04-29 KR KR1020227041835A patent/KR20230006882A/en active Search and Examination
- 2021-04-29 WO PCT/US2021/029961 patent/WO2021222617A2/en unknown
- 2021-04-29 AU AU2021263458A patent/AU2021263458A1/en active Pending
- 2021-04-29 US US17/244,640 patent/US20210337881A1/en active Pending
- 2021-04-29 EP EP21727044.6A patent/EP4143837A2/en active Pending
- 2021-04-29 JP JP2022566130A patent/JP2023524691A/en active Pending
- 2021-04-29 WO PCT/US2021/029969 patent/WO2021222625A1/en unknown
- 2021-04-29 CN CN202180032236.1A patent/CN115485781A/en active Pending
- 2021-04-29 JP JP2022566090A patent/JP2023524689A/en active Pending
- 2021-04-29 IL IL297670A patent/IL297670A/en unknown
- 2021-04-29 US US17/244,709 patent/US20210338948A1/en active Pending
- 2021-04-29 CN CN202180032242.7A patent/CN115485782A/en active Pending
- 2021-04-29 AU AU2021262800A patent/AU2021262800A1/en active Pending
- 2021-04-29 EP EP21729683.9A patent/EP4143838A1/en active Pending
- 2021-04-29 BR BR112022021907A patent/BR112022021907A2/en unknown
- 2021-04-29 CA CA3181602A patent/CA3181602A1/en active Pending
- 2021-04-29 KR KR1020227041662A patent/KR20230006880A/en active Search and Examination
- 2021-04-29 CA CA3181597A patent/CA3181597A1/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2018531055A5 (en) | ||
JP2017148550A (en) | Method and device using leakage detection | |
US20170246086A1 (en) | Chronotherapeutic dosing of medication and medication regimen adherence | |
WO2022068332A1 (en) | Sleep monitoring method and apparatus, electronic device, and computer-readable medium | |
ATE536801T1 (en) | ADAPTIVE PHYSIOLOGICAL MONITORING SYSTEM AND METHOD OF USE THEREOF | |
ES2659017T3 (en) | Apparatus and method to detect health deterioration | |
JP2009509638A (en) | Systems and methods for diagnosis and treatment of patient breathing patterns | |
WO2015138861A1 (en) | Systems and methods for detecting and diagnosing sleep disordered breathing | |
JP6884453B2 (en) | Patient situation prediction device, prediction model generation device, patient situation prediction program and patient situation prediction method | |
US20230364369A1 (en) | Systems and methods for automatic cycling or cycling detection | |
Beard et al. | Pilot study of the use of personal carbon monoxide monitoring to achieve radical smoking reduction | |
KR20220123086A (en) | Respiratory sensor measurement method and device | |
JP6891268B2 (en) | Respiratory gas supply device and its control method | |
JP2014233488A (en) | Sleep state determination device | |
MacLean et al. | A rational approach to home oxygen use in infants and children | |
US20210318660A1 (en) | Information processing apparatus, information processing method, non-transitory computer-readable storage medium with executable information processing program stored thereon, and information processing system | |
JPWO2021222625A5 (en) | ||
WO2018166795A1 (en) | Nocturnal asthma monitoring | |
JP7290406B2 (en) | Breathing gas supply device and its control method | |
US20240122265A1 (en) | Electronic Cigarette and Method for Controlling an Electronic Cigarette | |
CN108634954B (en) | Household simple apnea monitoring device | |
US9615743B2 (en) | Method for generating an alarm during the monitoring of a patient and device therefor | |
WO2021094380A1 (en) | Inhaler with stress monitoring | |
Ganesha et al. | Heart rate variability during sleep in detoxified alcohol-dependent males: A comparison with healthy controls | |
JP3627741B2 (en) | Sleep breathing information measuring device |