JPWO2021217206A5 - - Google Patents
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- Publication number
- JPWO2021217206A5 JPWO2021217206A5 JP2022564217A JP2022564217A JPWO2021217206A5 JP WO2021217206 A5 JPWO2021217206 A5 JP WO2021217206A5 JP 2022564217 A JP2022564217 A JP 2022564217A JP 2022564217 A JP2022564217 A JP 2022564217A JP WO2021217206 A5 JPWO2021217206 A5 JP WO2021217206A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- pharmaceutical composition
- acid sequence
- seq
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 52
- 239000008194 pharmaceutical composition Substances 0.000 claims description 47
- 102000004169 proteins and genes Human genes 0.000 claims description 41
- 108090000623 proteins and genes Proteins 0.000 claims description 41
- 239000012634 fragment Substances 0.000 claims description 18
- 150000001413 amino acids Chemical class 0.000 claims description 13
- 239000000427 antigen Substances 0.000 claims description 12
- 102000036639 antigens Human genes 0.000 claims description 12
- 108091007433 antigens Proteins 0.000 claims description 12
- 230000028993 immune response Effects 0.000 claims description 12
- 102000004245 Proteasome Endopeptidase Complex Human genes 0.000 claims description 11
- 108090000708 Proteasome Endopeptidase Complex Proteins 0.000 claims description 11
- 102100027723 Endogenous retrovirus group K member 6 Rec protein Human genes 0.000 claims description 10
- 101710091045 Envelope protein Proteins 0.000 claims description 10
- 101710188315 Protein X Proteins 0.000 claims description 10
- 229940044655 toll-like receptor 9 agonist Drugs 0.000 claims description 10
- 206010011831 Cytomegalovirus infection Diseases 0.000 claims description 6
- 230000001939 inductive effect Effects 0.000 claims description 6
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims description 4
- 230000028996 humoral immune response Effects 0.000 claims description 4
- 230000021633 leukocyte mediated immunity Effects 0.000 claims description 4
- 230000001681 protective effect Effects 0.000 claims description 4
- 108010035452 HLA-A1 Antigen Proteins 0.000 claims description 2
- 108010029389 Simplexvirus glycoprotein B Proteins 0.000 claims description 2
- 239000003085 diluting agent Substances 0.000 claims description 2
- 239000003937 drug carrier Substances 0.000 claims description 2
- 230000036039 immunity Effects 0.000 claims description 2
- 102000039446 nucleic acids Human genes 0.000 claims description 2
- 108020004707 nucleic acids Proteins 0.000 claims description 2
- 150000007523 nucleic acids Chemical class 0.000 claims description 2
- KDWFDOFTPHDNJL-TUBOTVQJSA-N odn-2006 Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@H]2[C@H]([C@@H](O[C@@H]2COP(O)(=S)O[C@H]2[C@H]([C@@H](O[C@@H]2COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@H]2[C@H]([C@@H](O[C@@H]2COP(O)(=O)O[C@@H]2[C@H](O[C@H](C2)N2C(NC(=O)C(C)=C2)=O)COP(O)(=O)O[C@H]2[C@H]([C@@H](O[C@@H]2COP(O)(=S)O[C@H]2[C@H]([C@@H](O[C@@H]2COP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=C(C(NC(N)=N3)=O)N=C2)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=C(C(NC(N)=N3)=O)N=C2)OP(S)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C(N=C(N)C=C2)=O)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)OP(O)(=O)OC[C@@H]2[C@H](C[C@@H](O2)N2C(NC(=O)C(C)=C2)=O)O)N2C3=C(C(NC(N)=N3)=O)N=C2)O)N2C(N=C(N)C=C2)=O)O)N2C3=C(C(NC(N)=N3)=O)N=C2)O)N2C3=C(C(NC(N)=N3)=O)N=C2)O)N2C(N=C(N)C=C2)=O)O)[C@@H](O)C1 KDWFDOFTPHDNJL-TUBOTVQJSA-N 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 229960005486 vaccine Drugs 0.000 claims description 2
- 238000000034 method Methods 0.000 description 7
- ODIHLEYTPVYAPY-UHFFFAOYSA-N 3-[2-fluoro-4-[[3-[2-methyl-4-(3-methylsulfonylpropoxy)phenyl]phenyl]methylamino]phenyl]propanoic acid Chemical compound CC1=CC(OCCCS(C)(=O)=O)=CC=C1C1=CC=CC(CNC=2C=C(F)C(CCC(O)=O)=CC=2)=C1 ODIHLEYTPVYAPY-UHFFFAOYSA-N 0.000 description 1
- 238000004590 computer program Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2020901334A AU2020901334A0 (en) | 2020-04-28 | Pharmaceutical composition | |
| AU2020901334 | 2020-04-28 | ||
| PCT/AU2021/050385 WO2021217206A1 (en) | 2020-04-28 | 2021-04-28 | Human cytomegalovirus polyepitope vaccine composition |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023526766A JP2023526766A (ja) | 2023-06-23 |
| JP2023526766A5 JP2023526766A5 (https=) | 2024-06-11 |
| JPWO2021217206A5 true JPWO2021217206A5 (https=) | 2024-06-11 |
Family
ID=78373118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022564217A Pending JP2023526766A (ja) | 2020-04-28 | 2021-04-28 | ヒトサイトメガロウイルスポリエピトープワクチン組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230173061A1 (https=) |
| EP (1) | EP4143208A4 (https=) |
| JP (1) | JP2023526766A (https=) |
| KR (1) | KR20230005899A (https=) |
| CN (1) | CN117202929A (https=) |
| AU (1) | AU2021263337A1 (https=) |
| BR (1) | BR112022021769A2 (https=) |
| CA (1) | CA3177020A1 (https=) |
| IL (1) | IL297736A (https=) |
| MX (1) | MX2022013490A (https=) |
| WO (1) | WO2021217206A1 (https=) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2889064A1 (en) * | 2012-10-19 | 2014-04-24 | The Council Of The Queensland Institute Of Medical Research | Improved human herpesvirus immunotherapy |
| JP2019520332A (ja) * | 2016-05-23 | 2019-07-18 | ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ | Ｃｍｖエピトープ |
-
2021
- 2021-04-28 WO PCT/AU2021/050385 patent/WO2021217206A1/en not_active Ceased
- 2021-04-28 US US17/921,945 patent/US20230173061A1/en active Pending
- 2021-04-28 AU AU2021263337A patent/AU2021263337A1/en active Pending
- 2021-04-28 JP JP2022564217A patent/JP2023526766A/ja active Pending
- 2021-04-28 IL IL297736A patent/IL297736A/en unknown
- 2021-04-28 KR KR1020227040909A patent/KR20230005899A/ko active Pending
- 2021-04-28 EP EP21796930.2A patent/EP4143208A4/en active Pending
- 2021-04-28 MX MX2022013490A patent/MX2022013490A/es unknown
- 2021-04-28 BR BR112022021769A patent/BR112022021769A2/pt unknown
- 2021-04-28 CA CA3177020A patent/CA3177020A1/en active Pending
- 2021-04-28 CN CN202180045562.6A patent/CN117202929A/zh not_active Withdrawn
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