JPWO2021209298A5

JPWO2021209298A5 -

Info

Publication number: JPWO2021209298A5
Application number: JP2022563019A
Authority: JP
Publication date: 2024-04-17

Claims

1. An apparatus for therapeutic treatment of the retina, comprising:
at least one radiation source for delivering therapeutically effective radiation;
a control unit for driving the irradiation source, the control unit being programmed to deliver therapeutically effective radiation from the irradiation source to a retina of the eye at a predetermined irradiation time and at a predetermined irradiation intensity;
Equipped with
a holding and positioning device for holding an optical lens element at a defined position and orientation in front of a patient's eye, said optical lens element having a radiation transmitting concave surface for placement on a closed eyelid, said irradiation source cooperating with said optical lens element to deliver therapeutically effective radiation through said optical lens element to a retina;
Device.

the optical lens element comprises a diffuser adapted to diffuse the radiation from the illumination source onto the radiation-transmitting concave surface.
2. The apparatus of claim 1.

The diffuser is designed as an integrating sphere or as a layer of semi-permeable material, in particular polytetrafluoroethylene;
3. The apparatus of claim 2.

The optical lens element is provided with a thermal heating or cooling device.
4. Apparatus according to any one of claims 1 to 3.

A set of interface elements;
one of the sets is mountable to the concave surface of the optical lens element;
The set includes:
a first interface element having a first refractive index;
a second interface element having a second refractive index different from the first refractive index;
Equipped with
5. Apparatus according to any one of claims 1 to 4.

The holding and positioning device is designed as a partial face mask that at least partially covers the eye area of the face,
6. Apparatus according to any one of claims 1 to 5.

The partial face mask comprises:
by a band worn around the head, or by a strap or a retaining element that goes over the ear, such as a glasses temple, or by a suction cup.
held in place on the patient's face,
7. The apparatus of claim 6.

the radiation source is fixed to the holding and positioning device and is in a treatment position on the radiation axis, in particular together with the pupil and the diffuser ;
8. Apparatus according to any one of claims 1 to 7.

a second illumination source is disposed on the illumination base device at a location remote from the holding and positioning device;
the radiation is guided from the radiation base device to the holding and positioning device by a flexible radiation guide;
9. The apparatus of claim 8.

the illumination source is disposed on an illumination base device at a location remote from the holding and positioning device;
the radiation is guided from the radiation base device to the holding and positioning device by a flexible radiation guide;
8. Apparatus according to any one of claims 1 to 7.

The concave surface is designed to be in superficial contact with the eye or closed eyelid over a contact area of at least ¹ cm2;
11. Apparatus according to any one of claims 1 to 10.

the optical lens element having an eyelid sensor signal-coupled to the control unit for detecting a closed eyelid;
The control unit is designed to activate the illumination source only when the eyelid sensor detects a signal indicative of closed eyelids.
12. Apparatus according to any one of claims 1 to 11.

a base station having a receiver for said holding and positioning device;
The receiving device includes a heating means or a cooling means for heating or cooling the optical lens element.
13. Apparatus according to any one of claims 1 to 12.

An input user interface;
a graphic output user interface for outputting graphic information;
Equipped with
the control unit is programmed to, in an information step, present information regarding a subsequent therapeutic treatment step to the patient via the graphic output user interface and to execute the therapeutic step after the information step;
the irradiation time and the irradiation intensity correspond to a treatment mode input via the input user interface and/or output via the graphic output user interface;
14. Apparatus according to any one of claims 1 to 13.

The control unit
between the information step and the treatment step, in an input step, requesting user input via the input user interface;
initiating said treatment step upon receipt of a predetermined user input ;
15. The apparatus of claim 14.

The control unit
receiving user-related personal information via the input user interface;
identifying a user identity from a user identity data store of the control unit based on the user-related personal information;
Executing a predetermined treatment step stored for the user ID in a treatment program data memory in response to the user ID ;
16. Apparatus according to claim 14 or 15.

the input user interface comprises a digital image acquisition unit;
The control unit
receiving image data from the digital image acquisition unit;
determining a user ID based on the image data, in particular, determining the user ID based on image data describing the user's iris shape based on iris authentication ;
17. The apparatus of claim 16.

said control unit and said graphical output user interface being disposed on an illumination- based device;
the illumination-based device further comprising an illumination guide device for directing the radiation emitted from the illumination source to the optical lens element held on a holding and positioning device in front of a patient's eye.
Apparatus according to any one of claims 14 to 17 and claims 9 to 10.

The control unit is provided in a smart tablet, a laptop, or a smartphone.
19. Apparatus according to any one of claims 1 to 18.

said holding and positioning device having a total weight and size that can be supported on the patient's head by said holding and positioning device alone;
20. Apparatus according to any one of claims 1 to 19.

the illumination source having two beam exit directions spaced apart from one another for simultaneously irradiating both eyes of a patient;
21. Apparatus according to any one of claims 1 to 20.

The radiation source comprises:
a first optical system including at least one first optical lens, a first optical collimator, and/or a first optical filter unit;
a second optical system spaced apart from the first optical system along an illumination optical path axis and including at least one second optical lens, a second optical collimator, and/or a second optical filter unit;
Equipped with
22. Apparatus according to any one of claims 1 to 21.

The control unit
storing and controlling a treatment plan including at least a first treatment procedure and a second treatment procedure for a user;
Controlling a first treatment procedure for a user;
storing a completion time of the first treatment procedure;
commencing a second treatment procedure under the condition that a minimum period of time has elapsed since the completion time of the first treatment procedure .
23. Apparatus according to any one of claims 1 to 22.

The control unit
receiving diagnostic data characterizing a physical condition via an input user interface;
generating treatment data following the treatment procedure that characterizes the treatment procedure performed;
transmitting data packets containing said diagnostic data and said therapeutic data to a receiving device of a specialist computer via a data transmission unit;
receiving command data from a transmission device of the specialized computer via the data transmission unit;
controlling said radiation source to perform a treatment procedure characterized by said instruction data ;
24. Apparatus according to any one of claims 14 to 23.

The control unit
receiving diagnostic data characterizing a physical condition via an input user interface;
comparing said diagnostic data with predetermined physical condition data stored in an electronic data memory of said control unit;
selecting a subsequent treatment protocol from a plurality of treatment protocols stored in the electronic data memory of the control unit based on corresponding to one of the stored physical condition data , exceeding a physical condition defined in the physical condition data, or falling below a physical condition defined in the physical condition data;
controlling said radiation source to perform said selected treatment procedure ;
25. Apparatus according to any one of claims 14 to 24.

the input user interface comprises a digital image capture device;
the diagnostic data includes image acquisition data describing an image of the treated tissue;
26. Apparatus according to claim 24 or 25.