JPWO2021065306A1 - - Google Patents

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Publication number
JPWO2021065306A1
JPWO2021065306A1 JP2021550469A JP2021550469A JPWO2021065306A1 JP WO2021065306 A1 JPWO2021065306 A1 JP WO2021065306A1 JP 2021550469 A JP2021550469 A JP 2021550469A JP 2021550469 A JP2021550469 A JP 2021550469A JP WO2021065306 A1 JPWO2021065306 A1 JP WO2021065306A1
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JP
Japan
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JP2021550469A
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Japanese (ja)
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JP7718270B2 (ja
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Priority to JP2025042343A priority Critical patent/JP2025098086A/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/535Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/14Post-translational modifications [PTMs] in chemical analysis of biological material phosphorylation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2814Dementia; Cognitive disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
JP2021550469A 2019-09-30 2020-09-02 血液試料を検体とするタウタンパク質検出方法 Active JP7718270B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025042343A JP2025098086A (ja) 2019-09-30 2025-03-17 血液試料を検体とするタウタンパク質検出方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019179385 2019-09-30
JP2019179385 2019-09-30
PCT/JP2020/033211 WO2021065306A1 (ja) 2019-09-30 2020-09-02 血液試料を検体とするタウタンパク質検出方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025042343A Division JP2025098086A (ja) 2019-09-30 2025-03-17 血液試料を検体とするタウタンパク質検出方法

Publications (2)

Publication Number Publication Date
JPWO2021065306A1 true JPWO2021065306A1 (https=) 2021-04-08
JP7718270B2 JP7718270B2 (ja) 2025-08-05

Family

ID=75338154

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021550469A Active JP7718270B2 (ja) 2019-09-30 2020-09-02 血液試料を検体とするタウタンパク質検出方法
JP2025042343A Pending JP2025098086A (ja) 2019-09-30 2025-03-17 血液試料を検体とするタウタンパク質検出方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025042343A Pending JP2025098086A (ja) 2019-09-30 2025-03-17 血液試料を検体とするタウタンパク質検出方法

Country Status (4)

Country Link
US (1) US20220365102A1 (https=)
EP (1) EP4040153A4 (https=)
JP (2) JP7718270B2 (https=)
WO (1) WO2021065306A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023056410A1 (en) * 2021-10-01 2023-04-06 Integrated Neurologics LLC Methods and devices for detecting cerebrospinal fluid leakage
WO2024214588A1 (ja) * 2023-04-13 2024-10-17 国立研究開発法人量子科学技術研究開発機構 被験者の脳のタウタンパク質の蓄積量を推定する方法及び装置
JP7450995B1 (ja) 2023-04-13 2024-03-18 国立研究開発法人量子科学技術研究開発機構 被験者の脳のタウタンパク質の蓄積量を推定する方法及び装置

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5492812A (en) * 1991-08-01 1996-02-20 Provost, Fellows And Scholars Of Trinity College Diagnostic method for Alzheimer's disease by screening for tau-peptides in the blood of a patient
JPH08503898A (ja) * 1992-03-05 1996-04-30 ロウバー グループ リミテッド 複式射出成形方法および当該方法で形成される成形体
US20150018223A1 (en) * 2010-01-28 2015-01-15 University Of Massachusetts Lowell Methods of diagnosing tau-associated neurodegenerative diseases
WO2017138497A1 (ja) * 2016-02-08 2017-08-17 シスメックス株式会社 被検物質の検出方法および被検物質の検出用試薬キット
JP2017531796A (ja) * 2014-09-30 2017-10-26 ワシントン・ユニバーシティWashington University タウの動態測定
WO2018106776A2 (en) * 2016-12-07 2018-06-14 Genentech, Inc. Anti-tau antibodies and methods of use
JP2019027952A (ja) * 2017-07-31 2019-02-21 京都府公立大学法人 リン酸化タウタンパク質の測定方法
US20190271710A1 (en) * 2018-03-05 2019-09-05 Janssen Pharmaceutica Nv Assays to detect neurodegeneration
WO2020105700A1 (ja) * 2018-11-22 2020-05-28 富士レビオ株式会社 抗体コンジュゲート

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013795A1 (en) * 1992-12-14 1994-06-23 N.V. Innogenetics S.A. Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications
PL2857039T3 (pl) 2012-05-31 2020-05-18 Osaka City University Środek terapeutyczny lub środek profilaktyczny na otępienie

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5492812A (en) * 1991-08-01 1996-02-20 Provost, Fellows And Scholars Of Trinity College Diagnostic method for Alzheimer's disease by screening for tau-peptides in the blood of a patient
JPH08503898A (ja) * 1992-03-05 1996-04-30 ロウバー グループ リミテッド 複式射出成形方法および当該方法で形成される成形体
US20150018223A1 (en) * 2010-01-28 2015-01-15 University Of Massachusetts Lowell Methods of diagnosing tau-associated neurodegenerative diseases
JP2017531796A (ja) * 2014-09-30 2017-10-26 ワシントン・ユニバーシティWashington University タウの動態測定
WO2017138497A1 (ja) * 2016-02-08 2017-08-17 シスメックス株式会社 被検物質の検出方法および被検物質の検出用試薬キット
WO2018106776A2 (en) * 2016-12-07 2018-06-14 Genentech, Inc. Anti-tau antibodies and methods of use
JP2019027952A (ja) * 2017-07-31 2019-02-21 京都府公立大学法人 リン酸化タウタンパク質の測定方法
US20190271710A1 (en) * 2018-03-05 2019-09-05 Janssen Pharmaceutica Nv Assays to detect neurodegeneration
WO2020105700A1 (ja) * 2018-11-22 2020-05-28 富士レビオ株式会社 抗体コンジュゲート

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEN ZHICHENG ET AL.: "Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzh", ALZHEIMER'S & DEMENTIA, vol. 15, no. 3, JPN6020043680, 9 November 2018 (2018-11-09), pages 487 - 496, ISSN: 0005485379 *

Also Published As

Publication number Publication date
JP2025098086A (ja) 2025-07-01
US20220365102A1 (en) 2022-11-17
EP4040153A1 (en) 2022-08-10
WO2021065306A1 (ja) 2021-04-08
JP7718270B2 (ja) 2025-08-05
EP4040153A4 (en) 2023-07-26

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