JPWO2021042217A5 - - Google Patents
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- JPWO2021042217A5 JPWO2021042217A5 JP2022513989A JP2022513989A JPWO2021042217A5 JP WO2021042217 A5 JPWO2021042217 A5 JP WO2021042217A5 JP 2022513989 A JP2022513989 A JP 2022513989A JP 2022513989 A JP2022513989 A JP 2022513989A JP WO2021042217 A5 JPWO2021042217 A5 JP WO2021042217A5
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Claims (13)
ａ）封じ込め装置（１）は、ハウジング（１０）に囲まれた作業室（１１）を有しており、
ｂ）封じ込め装置（１）内にはロボット（１７）が設置されており、ロボット（１７）は、旋回範囲にわたって動かせるアーム機構（１９）を有しており、
ｃ）回収容器（７）が存在する場合、回収容器（７）は作業室（１１）から供給を受ける入口を有しており、また、貯蔵容器（８）が存在する場合、貯蔵容器（８）は作業室（１１）へと供給を行う出口を有しており、
ｄ）容器（６）は、少なくとも第１閉鎖要素（６１）を用いて閉鎖可能である、装置において、
ｅ）アーム機構（１９）はツールキャリア（３）に接続されており、ツールキャリア（３）のベース（３０）には少なくとも、容器（６）を把持するためのクランプ要素（３２）、第１閉鎖要素（６１）を把持するためのバキュームリフター（３３）、及び、ダブルフラップの受動部（３１）が備えられており、
ｆ）回収容器（７）への入口及び／又は貯蔵容器（８）の出口には移送ヘッド（４）が取り付けられていてそれぞれが作業室（１１）内に突出しており、
ｇ）受動部（３１）は、移送ヘッド（４）内に含まれている能動部（４１）と共にダブルフラップを形成することを特徴とする装置。 For aseptically transferring the powder (9), i.e. emptying the contents of the container (6) filled with the powder (9) into the collection container (7) and/or from the storage container (8) An installation comprising a containment device (1) for filling a container (6) with a powder (9),
a) the containment device (1) has a working chamber (11) surrounded by a housing (10),
b) a robot (17) is installed within the containment device (1), the robot (17) having an arm mechanism (19) movable through a swivel range;
c) If a collection vessel (7) is present, the collection vessel (7) has an inlet fed from the working chamber (11) and if a storage vessel (8) is present, the storage vessel (8 ) has an outlet feeding into the working chamber (11),
d) a device wherein the container (6) is closable with at least a first closure element (61),
e) The arm mechanism (19) is connected to the tool carrier (3), the base (30) of which has at least a clamping element (32) for gripping the container (6), a first A vacuum lifter (33) for gripping the closure element (61) and a double flap passive part (31) are provided,
f) the inlet to the collection vessel (7) and/or the outlet to the storage vessel (8) is fitted with a transfer head (4) each protruding into the working chamber (11),
g) A device characterized in that the passive part (31) forms a double flap with the active part (41) contained in the transfer head (4).
ａ）ツールキャリア（３）のベース（３０）が、アーム機構（１９）に接続するための接続フランジ（３００）を有しており、接続フランジ（３００）には秤量セル（３０２）を設置することができ、及び、
ｂ）ベース（３０）には位置決め部材（３０１）が設けられており、位置決め部材（３０１）は、移送ヘッド（４）のベース（４０）に配置された相補的なロッキング部材（４０１）に確動的及び摩擦結合的に接続するためのものであり、また、ツールキャリア（３）と移送ヘッド（４）との間の耐圧的な組み付けを確保するものであることを特徴とする装置。 2. The device of claim 1, wherein
a) The base (30) of the tool carrier (3) has a connection flange (300) for connection to the arm mechanism (19), on which the weighing cell (302) is mounted. and
b) The base (30) is provided with a positioning member (301) which is secured to a complementary locking member (401) located on the base (40) of the transfer head (4). A device for a dynamic and frictional connection and for ensuring a pressure-resistant assembly between the tool carrier (3) and the transfer head (4).
ａ）ツールキャリア（３）のベース（３０）は、吸引ツール（３４）又は洗浄・殺菌ツール（３５）又はつば出しツール（３６）を一時的に収容できるようになっており、
ｂ）ツール（３４、３５、３６）をツールキャリア（３）のベース（３０）に固定する役割はクランプ要素（３２）が単独で又は追加的に担っており、
ｃ）吸引ツール（３４）は、作業室（１１）内においてツールキャリア（３）及び第１閉鎖要素（６１）を洗浄し、
ｄ）洗浄・殺菌ツール（３５）は、作業室（１１）内においてダブルフラップの受動部（３１）及び能動部（４１）も含めて回収容器（７）の洗浄及び殺菌を行い、及び、
ｅ）つば出しツール（３６）は、作業室（１１）内において第２閉鎖要素（６２）を容器（６）に取り付けることを特徴とする装置。 3. A device according to claim 1 or 2, wherein
a) the base (30) of the tool carrier (3) is adapted to temporarily accommodate a suction tool (34) or a cleaning and sterilizing tool (35) or a fluffing tool (36);
b) the clamping element (32) is solely or additionally responsible for fixing the tools (34, 35, 36) to the base (30) of the tool carrier (3),
c) the suction tool (34) cleans the tool carrier (3) and the first closure element (61) in the working chamber (11);
d) cleaning and sterilization tools (35) clean and sterilize the collection vessel (7), including the passive part (31) and the active part (41) of the double flap, in the working chamber (11); and
e) A device characterized in that the flanging tool (36) attaches the second closure element (62) to the container (6) within the working chamber (11).
ツール（３４、３５、３６）は、作業室（１１）内においてパークステーション（１４）に着脱可能に置かれており、ロボット（１７）のアーム機構（１９）に設けられたツールキャリア（３）により把持されて使用されることを特徴とする装置。 4. A device according to claim 3, wherein
The tools (34, 35, 36) are detachably placed on the park station (14) in the working chamber (11), and the tool carrier (3) provided on the arm mechanism (19) of the robot (17). A device characterized by being held and used by
ａ）空にすべき容器（６）から粉体（９）の残りを落とすためのバイブレータ（３７）；
ｂ）空にすべき容器（６）に第２閉鎖要素（６２）が存在する場合には、これを取り除くためのリッパーフック（３８）、及び
ｃ）検査目的で粉体（９）の試料を採取するためのサンプリングツール（３９）も有することを特徴とする装置。 A device according to any one of claims 1 to 4, wherein the tool carrier (3) in its fully equipped state comprises:
a) a vibrator (37) for dropping the rest of the powder (9) from the container (6) to be emptied;
b) a ripper hook (38) for removing the second closure element (62), if present, on the container (6) to be emptied; and c) a sample of the powder (9) for inspection purposes. A device characterized in that it also has a sampling tool (39) for sampling.
ａ）第１閉鎖要素（６１）は、容器（６）の口に載せられる蓋又は容器（６）の口に挿入される栓として構成されており、また、
ｂ）第２閉鎖要素（６２）は、第１閉鎖要素（６１）の上において容器（６）に取り付けられるフランジ付きキャップとして作られていることを特徴とする装置。 A device according to claims 1 and 3,
a) the first closure element (61) is configured as a lid that rests on the mouth of the container (6) or a plug that is inserted into the mouth of the container (6), and
b) A device characterized in that the second closure element (62) is made as a flanged cap that is attached to the container (6) over the first closure element (61).
ａ）ツールキャリア（３）を無菌状態で作業室（１１）に運び入れるために、気密に覆われた移送容器（２）が設けられており、また、ハウジング（１０）には移送ポート（１２）が設けられおり、
ｂ）移送容器（２）は、ツールキャリア（３）を受け入れて移送ポート（１２）にドッキングするためのものであり、
ｃ）移送容器（２）が移送ポート（１２）にドッキングした状態において、移送ポート（１２）及び移送容器（２）が開いている場合、ツールキャリア（３）は、ロボット（１７）に把持されて移送容器（２）から作業室（１１）内へと引き入れられることを特徴とする装置。 A device according to any one of claims 1 to 6,
a) An airtightly covered transfer container (2) is provided for aseptically transporting the tool carrier (3) into the working chamber (11), and the housing (10) is provided with a transfer port (12). ) is provided,
b) the transfer container (2) is for receiving and docking the tool carrier (3) to the transfer port (12);
c) With transfer container (2) docked to transfer port (12), tool carrier (3) is gripped by robot (17) when transfer port (12) and transfer container (2) are open. device, characterized in that it is drawn from the transport container (2) into the working chamber (11) by means of a
ａ）空にすべき容器（６）又は充填すべき容器（６）を除染された状態で作業室（１１）に運び入れるために、気密に覆われたロック（２３）が設けられており、また、ハウジング（１０）にはロックポート（１３）が設けられており、
ｂ）ロック（２３）は、容器（６）を受け入れてロックポート（１３）にドッキングするためのものであり、及び
ｃ）ロックポート（１３）にロック（２３）がドッキングされた状態において、ロックポート（１３）及びロック（２３）が開いている場合、容器（６）は、ロボット（１７）により把持されてロック（２３）から作業室（１１）内へと引き入れられること、又は、搬送装置によって作業室（１１）内へと運ばれることを特徴とする装置。 A device according to any one of claims 1 to 7,
a) an airtightly covered lock (23) is provided for transporting the container (6) to be emptied or filled (6) in a decontaminated condition into the working chamber (11); , and the housing (10) is provided with a lock port (13),
b) the lock (23) is for receiving and docking the container (6) in the lock port (13); and c) with the lock (23) docked in the lock port (13), the lock If the port (13) and lock (23) are open, the container (6) can be grasped by the robot (17) and drawn from the lock (23) into the working chamber (11) or A device characterized in that it is carried into the working chamber (11) by
接続フランジ（３００）内に配置された秤量セル（３０２）が、比較により重量を求めること、すなわち、
（ａ）粉体（９）が充填された容器（６）の中身を回収容器（７）に空ける工程において、出発状態における粉体（９）が充填された容器（６）と空になった容器（６）との間の比較、又は、
（ｂ）空の容器（６）に貯蔵容器（８）から粉体（９）を充填する工程において、出発状態における空の容器（６）と粉体（９）が充填された容器（６）との間の比較により重量を求めることを特徴とする装置。 A device according to any one of claims 2 to 8,
A weighing cell (302) arranged in the connecting flange (300) determines the weight by comparison, i.e.
(a) in the step of emptying the contents of the container (6) filled with the powder (9) into the collection container (7), the container (6) filled with the powder (9) in the starting state is emptied; comparison with container (6), or
(b) in the step of filling an empty container (6) with powder (9) from a storage container (8), the empty container (6) in the starting state and the container (6) filled with powder (9); A device for determining weight by comparison between
ａ）検査目的で粉体（９）から試料を採取するためのサンプリングツール（３９）が、粉体（９）が充填された容器（６）の中身を回収容器（７）に空ける工程において、又は、空の容器（６）に貯蔵容器（８）から粉体（９）を充填する工程において使用されること、又は、
ｂ）代替的に、装置が、取り扱われる粉体（９）の特性をサンプリングツール（３９）を用いて検査することのみを目的としたものであることを特徴とする装置。 A device according to any one of claims 5 to 9,
a) in the step in which a sampling tool (39) for taking a sample from the powder (9) for inspection purposes empties the contents of the container (6) filled with the powder (9) into a collection container (7), or in the process of filling an empty container (6) with powder (9) from a storage container (8), or
b) Alternatively, a device characterized in that the device is only intended to test the properties of the powder (9) to be handled using a sampling tool (39).
ａ）ロック（２３）は、空になった又は充填された容器（６）を作業室（１１）から運び出すためにも、また、取り扱う粉体（９）の特性を検査するためにサンプリングツール（３９）を用いて試験量を採取する目的で、粉体（９）が充填された容器（６）を作業室（１１）に運び入れるため、もしくは、作業室（１１）から運び出すためにも使用できること、又は、
ｂ）空になった又は充填された容器（６）を作業室（１１）から運び出すため、また、取り扱う粉体（９）の特性を検査するためにサンプリングツール（３９）を用いて試験量を採取する目的で、粉体（９）が充填された容器（６）を作業室（１１）に運び入れるため、もしくは、作業室（１１）から運び出すために、封じ込め装置（１）には、第２ロック又はマウスホールが設けられていることを特徴とする装置。 A device according to claims 8 and 10,
a) The lock (23) is also used for transporting empty or filled containers (6) out of the working chamber (11) and also for sampling tools ( 39) for the purpose of taking a test quantity using what you can do, or
b) to carry empty or filled containers (6) out of the workroom (11) and to test the properties of the powders (9) to be handled using sampling tools (39) to measure test quantities; In order to bring the container (6) filled with the powder (9) into or out of the working chamber (11) for sampling purposes, the containment device (1) is equipped with a 2 lock or mouthhole provided.
空の容器（６）に貯蔵容器（８）から粉体（９）を充填する工程において、貯蔵容器（８）と移送ヘッド（４）との間には粉体（９）の所望の充填量を分配するための計量装置（８０）が配置されていることを特徴とする装置。 A device according to any one of claims 1 to 11,
In the process of filling an empty container (6) with powder (9) from a storage container (8), there is a desired charge of powder (9) between the storage container (8) and the transfer head (4). A device characterized in that a metering device (80) is arranged for dispensing the
ａ）回収容器（７）に付属する移送ヘッド（４）が封じ込め装置（１）のハウジング（１０）に、好ましくは床材に固定されており、移送ヘッド（４）から回収容器（７）へと導管部が延びており、及び、
ｂ）貯蔵容器（８）に付属する移送ヘッド（４）が、封じ込め装置（１）のハウジング（１０）に、好ましくは天井材に固定されていることを特徴とする装置。 A device according to any one of claims 1 to 12,
a) the transfer head (4) associated with the collection vessel (7) is fixed to the housing (10) of the containment device (1), preferably to the flooring, from the transfer head (4) to the collection vessel (7); and a conduit extend, and
b) A device characterized in that the transfer head (4) associated with the storage container (8) is fixed to the housing (10) of the containment device (1), preferably to the ceiling.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19405014.2 | 2019-09-05 | ||
| EP19405014.2A EP3789305B1 (en) | 2019-09-05 | 2019-09-05 | Installation comprising a container for aseptically filling a powder |
| PCT/CH2020/000010 WO2021042217A1 (en) | 2019-09-05 | 2020-08-12 | System comprising containment equipment for the aseptic transfer of a powder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022547842A JP2022547842A (en) | 2022-11-16 |
| JPWO2021042217A5 true JPWO2021042217A5 (en) | 2023-08-01 |
Family
ID=67998428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513989A Pending JP2022547842A (en) | 2019-09-05 | 2020-08-12 | Apparatus with a containment device for aseptically transferring powders |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220388702A1 (en) |
| EP (1) | EP3789305B1 (en) |
| JP (1) | JP2022547842A (en) |
| KR (1) | KR20220053584A (en) |
| CN (1) | CN114341003B (en) |
| BR (1) | BR112022002428A2 (en) |
| CA (1) | CA3148176A1 (en) |
| DK (1) | DK3789305T3 (en) |
| WO (1) | WO2021042217A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102022100678A1 (en) * | 2022-01-12 | 2023-07-13 | Tt Innovation Ag | Transfer device, method and use of a transfer device for transferring at least one functional element into a process chamber |
| DE102022103828B3 (en) * | 2022-02-17 | 2023-07-27 | Gerhard Schubert Gesellschaft mit beschränkter Haftung | Packing Machine |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH10218128A (en) * | 1997-02-03 | 1998-08-18 | Toppan Printing Co Ltd | Sterlized filling equipment |
| EP0997154A1 (en) * | 1998-11-01 | 2000-05-03 | Newform N.V. | Sterilisable container with a sterilisable adapter for docking to a port of an isolation system. |
| US20040185521A1 (en) * | 2003-03-20 | 2004-09-23 | Shigeru Yoshida | Microorganism sampling method and microorganism sampling device |
| ATE532496T1 (en) * | 2005-05-16 | 2011-11-15 | Intelligent Hospital Systems Ltd | AUTOMATIC PHARMACY MIXING SYSTEM (APAS) |
| ITBO20060246A1 (en) * | 2006-04-05 | 2007-10-06 | Ima Spa | APPARATUS AND METHOD TO FEED WITH A PRODUCT A PACKAGING MACHINE. |
| US9021769B2 (en) * | 2010-03-03 | 2015-05-05 | Yuyama Mfg. Co., Ltd. | Medicament dispensing machine |
| EP2535034B1 (en) * | 2011-06-17 | 2014-04-23 | Kiro Robotics S.L. | Machine and method for the automatic preparation of intravenous medication |
| US20160050946A1 (en) * | 2013-03-15 | 2016-02-25 | Treasure Brands | Food product processing and packaging system and method |
| DK3033276T3 (en) * | 2013-08-16 | 2019-04-23 | Vanrx Pharmasystems Inc | PROCEDURE FOR FILLING PHARMACEUTICAL CONTAINERS |
| EP3068870B1 (en) * | 2013-11-13 | 2020-01-15 | Stempeutics Research Private Limited | A system and method for processing of biological tissue samples |
| JP6128019B2 (en) * | 2014-03-05 | 2017-05-17 | 株式会社安川電機 | Liquid transfer system, liquid transfer control method, liquid transfer control device, and drug manufacturing method |
| ITUB20150371A1 (en) * | 2015-05-05 | 2016-11-05 | Masmec S P A | SYSTEM FOR THE PREPARATION AND DOSAGE OF CHEMOTHERAPY DRUGS |
| US20180282681A1 (en) * | 2015-10-20 | 2018-10-04 | Rohto Pharmaceutical Co., Ltd. | Cell treatment apparatus |
| ITUA20161408A1 (en) * | 2016-03-07 | 2017-09-07 | Swisslog Italia Spa | Machine and procedure for the preparation of intravenous medicaments |
| IT201600084890A1 (en) * | 2016-08-11 | 2018-02-11 | Aea Srl | PLANT AND PROCEDURE FOR THE PREPARATION OF MEDICINAL PRODUCTS |
| EP3335844B1 (en) * | 2016-12-15 | 2019-10-30 | Pharma Integration S.R.L. | Constructive structure of a containment, intended for automated production of pharmaceutical or biotechnical article |
| EP3694465A4 (en) * | 2017-10-10 | 2021-07-28 | VANRX Pharmasystems Inc. | Apparatus and method for monitoring and controlling the filling of a container with a pharmaceutical fluid in an aseptic environment |
| CN109859406A (en) * | 2019-03-29 | 2019-06-07 | 江苏迅捷智能科技有限公司 | A kind of dispensing system and automatic medicine selling machine |
-
2019
- 2019-09-05 EP EP19405014.2A patent/EP3789305B1/en active Active
- 2019-09-05 DK DK19405014.2T patent/DK3789305T3/en active
-
2020
- 2020-08-12 CA CA3148176A patent/CA3148176A1/en active Pending
- 2020-08-12 JP JP2022513989A patent/JP2022547842A/en active Pending
- 2020-08-12 WO PCT/CH2020/000010 patent/WO2021042217A1/en active Application Filing
- 2020-08-12 KR KR1020227007314A patent/KR20220053584A/en unknown
- 2020-08-12 US US17/640,304 patent/US20220388702A1/en active Pending
- 2020-08-12 BR BR112022002428A patent/BR112022002428A2/en unknown
- 2020-08-12 CN CN202080062078.XA patent/CN114341003B/en active Active
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