JPWO2020210232A5 - - Google Patents

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JPWO2020210232A5
JPWO2020210232A5 JP2021559648A JP2021559648A JPWO2020210232A5 JP WO2020210232 A5 JPWO2020210232 A5 JP WO2020210232A5 JP 2021559648 A JP2021559648 A JP 2021559648A JP 2021559648 A JP2021559648 A JP 2021559648A JP WO2020210232 A5 JPWO2020210232 A5 JP WO2020210232A5
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JP
Japan
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seq
antibody
antigen
binding fragment
subject
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JP2021559648A
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Japanese (ja)
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JP2022525435A (ja
JP2022525435A5 (https=
JP7730295B2 (ja
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Priority claimed from PCT/US2020/027071 external-priority patent/WO2020210232A1/en
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Publication of JPWO2020210232A5 publication Critical patent/JPWO2020210232A5/ja
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JP2021559648A 2019-04-08 2020-04-07 Cd19抗体およびこれを使用する方法 Active JP7730295B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962831123P 2019-04-08 2019-04-08
US62/831,123 2019-04-08
PCT/US2020/027071 WO2020210232A1 (en) 2019-04-08 2020-04-07 Cd19 antibodies and methods of using the same

Publications (4)

Publication Number Publication Date
JP2022525435A JP2022525435A (ja) 2022-05-13
JP2022525435A5 JP2022525435A5 (https=) 2023-04-13
JPWO2020210232A5 true JPWO2020210232A5 (https=) 2023-04-13
JP7730295B2 JP7730295B2 (ja) 2025-08-27

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Family Applications (1)

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JP2021559648A Active JP7730295B2 (ja) 2019-04-08 2020-04-07 Cd19抗体およびこれを使用する方法

Country Status (8)

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EP (1) EP3953385A4 (https=)
JP (1) JP7730295B2 (https=)
KR (1) KR20220006065A (https=)
CN (1) CN114341176A (https=)
AU (1) AU2020270888A1 (https=)
CA (1) CA3136251A1 (https=)
IL (1) IL287039A (https=)
WO (1) WO2020210232A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12590148B2 (en) 2018-11-26 2026-03-31 Nkarta, Inc. Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
IL322315A (en) 2019-05-14 2025-09-01 Provention Bio Inc Methods and preparations for preventing type 1 diabetes
AU2021287998B2 (en) 2020-06-11 2026-03-12 Benaroya Research Institute At Virginia Mason Methods and compositions for preventing type 1 diabetes
LT4269444T (lt) 2020-08-14 2024-09-25 GammaDelta Therapeutics Limited Daugiaspecifiniai anti-tcr kintamos delta 1 antikūnai
CA3214628A1 (en) * 2021-04-06 2022-10-13 Memorial Sloan-Kettering Cancer Center Combination therapy with dexamethasone and tumor-specific t cell engaging multi-specific antibodies for treating cancer
US12565529B2 (en) 2021-05-24 2026-03-03 Provention Bio, Inc. Methods for treating type 1 diabetes
JP2024546804A (ja) * 2021-12-15 2024-12-26 ワイ-マブス セラピューティクス, インコーポレイテッド Sada複合体を含む製剤
CN119350497A (zh) * 2023-07-24 2025-01-24 星尘生物科技(上海)有限公司 人源化抗cd19单链可变区片段及其用途
AU2024359838A1 (en) * 2023-10-13 2026-04-23 Suzhou Ribo Life Science Co., Ltd. Conjugate, drug conjugate and composition, and preparation method and use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2398829A2 (en) * 2009-02-23 2011-12-28 Glenmark Pharmaceuticals S.A. Humanized antibodies that bind to cd19 and their uses
AU2013302696B9 (en) * 2012-08-14 2018-08-09 Ibc Pharmaceuticals, Inc. T-cell redirecting bispecific antibodies for treatment of disease
US20160326249A1 (en) * 2014-01-15 2016-11-10 Zymeworks Inc. Bi-specific cd3 and cd19 antigen-binding constructs
EA201790719A1 (ru) * 2014-09-26 2017-07-31 Макродженикс, Инк. Биспецифические моновалентные диатела, которые способны связывать cd19 и cd3, а также их применения
EA039859B1 (ru) * 2015-07-31 2022-03-21 Эмджен Рисерч (Мюник) Гмбх Биспецифические конструкты антител, связывающие egfrviii и cd3
CN110267982B (zh) * 2016-10-19 2024-02-23 斯克利普斯研究所 具有人源化靶向部分和/或经过优化的嵌合抗原受体相互作用结构域的嵌合抗原受体效应细胞开关以及其用途
SG10201912400VA (en) * 2017-04-24 2020-02-27 Kite Pharma Inc Humanized antigen-binding domains against cd19 and methods of use
AU2018337142B2 (en) * 2017-09-22 2025-07-03 Wuxi Biologics Ireland Limited. Novel bispecific CD3/CD19 polypeptide complexes
US11555072B2 (en) * 2017-09-23 2023-01-17 Memorial Sloan Kettering Cancer Center A33 antibody compositions and methods of using the same in radioimmunotherapy

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