JPWO2020163225A5 - - Google Patents
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- Publication number
- JPWO2020163225A5 JPWO2020163225A5 JP2021545378A JP2021545378A JPWO2020163225A5 JP WO2020163225 A5 JPWO2020163225 A5 JP WO2020163225A5 JP 2021545378 A JP2021545378 A JP 2021545378A JP 2021545378 A JP2021545378 A JP 2021545378A JP WO2020163225 A5 JPWO2020163225 A5 JP WO2020163225A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding fragment
- cancer
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025021046A JP2025072613A (ja) | 2019-02-05 | 2025-02-12 | 抗cd228抗体及び抗体薬物コンジュゲート |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962801590P | 2019-02-05 | 2019-02-05 | |
| US62/801,590 | 2019-02-05 | ||
| US201962824923P | 2019-03-27 | 2019-03-27 | |
| US62/824,923 | 2019-03-27 | ||
| US201962879660P | 2019-07-29 | 2019-07-29 | |
| US62/879,660 | 2019-07-29 | ||
| US201962882016P | 2019-08-02 | 2019-08-02 | |
| US62/882,016 | 2019-08-02 | ||
| US201962934424P | 2019-11-12 | 2019-11-12 | |
| US62/934,424 | 2019-11-12 | ||
| PCT/US2020/016381 WO2020163225A1 (en) | 2019-02-05 | 2020-02-03 | Anti-cd228 antibodies and antibody-drug conjugates |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025021046A Division JP2025072613A (ja) | 2019-02-05 | 2025-02-12 | 抗cd228抗体及び抗体薬物コンジュゲート |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022519273A JP2022519273A (ja) | 2022-03-22 |
| JP2022519273A5 JP2022519273A5 (https=) | 2023-02-13 |
| JPWO2020163225A5 true JPWO2020163225A5 (https=) | 2023-02-13 |
| JP7754715B2 JP7754715B2 (ja) | 2025-10-15 |
Family
ID=69740807
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021545378A Active JP7754715B2 (ja) | 2019-02-05 | 2020-02-03 | 抗cd228抗体及び抗体薬物コンジュゲート |
| JP2025021046A Withdrawn JP2025072613A (ja) | 2019-02-05 | 2025-02-12 | 抗cd228抗体及び抗体薬物コンジュゲート |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025021046A Withdrawn JP2025072613A (ja) | 2019-02-05 | 2025-02-12 | 抗cd228抗体及び抗体薬物コンジュゲート |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11617798B2 (https=) |
| EP (1) | EP3920968A1 (https=) |
| JP (2) | JP7754715B2 (https=) |
| KR (1) | KR20210125511A (https=) |
| CN (1) | CN113710271B (https=) |
| AU (1) | AU2020219732A1 (https=) |
| BR (1) | BR112021015477A2 (https=) |
| IL (1) | IL284974A (https=) |
| MX (1) | MX2021009138A (https=) |
| SG (1) | SG11202107551WA (https=) |
| TW (1) | TWI872044B (https=) |
| WO (1) | WO2020163225A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021207701A1 (en) | 2020-04-10 | 2021-10-14 | Seagen Inc. | Charge variant linkers |
| IL302402A (en) | 2020-11-08 | 2023-06-01 | Seagen Inc | Combined treatment |
| AU2022238571A1 (en) | 2021-03-18 | 2023-09-14 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| CA3221398A1 (en) | 2021-05-28 | 2022-12-01 | Seagen Inc. | Anthracycline antibody conjugates |
| IL315508A (en) | 2022-03-17 | 2024-11-01 | Seagen Inc | Camptothecin conjugates |
| WO2023215740A1 (en) * | 2022-05-06 | 2023-11-09 | Seagen Inc. | Immunomodulatory antibody-drug conjugates |
| CN119256007B (zh) * | 2022-05-31 | 2025-10-31 | 山东博安生物技术股份有限公司 | 抗cd228抗体及其药物偶联物 |
| KR20250071257A (ko) * | 2022-09-21 | 2025-05-21 | 씨젠 인크. | Cd137 및 cd228에 특이적인 신규한 융합 단백질 |
| WO2024064714A2 (en) * | 2022-09-21 | 2024-03-28 | Seagen Inc. | Antibodies that bind cd228 |
| CN121620532A (zh) * | 2023-07-28 | 2026-03-06 | 山东博安生物技术股份有限公司 | 一种适用于免疫组化检测cd228的诊断抗体 |
| WO2025090774A1 (en) | 2023-10-24 | 2025-05-01 | Seagen Inc. | Chemotherapeutic compounds and methods of use |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4474893A (en) | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4714681A (en) | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
| US5981216A (en) | 1985-04-01 | 1999-11-09 | Alusuisse Holdings A.G. | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| AU584417B2 (en) | 1985-04-01 | 1989-05-25 | Lonza Group Ag | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US4880935A (en) | 1986-07-11 | 1989-11-14 | Icrf (Patents) Limited | Heterobifunctional linking agents derived from N-succinimido-dithio-alpha methyl-methylene-benzoates |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| IL106992A (en) | 1988-02-11 | 1994-06-24 | Bristol Myers Squibb Co | Acylhydrazone derivatives of anthracycline and methods for their preparation |
| US5879936A (en) | 1988-04-18 | 1999-03-09 | Aluguisse Holding A.G. | Recombinant DNA methods, vectors and host cells |
| GB8809129D0 (en) | 1988-04-18 | 1988-05-18 | Celltech Ltd | Recombinant dna methods vectors and host cells |
| ATE120454T1 (de) | 1988-06-14 | 1995-04-15 | Cetus Oncology Corp | Kupplungsmittel und sterisch gehinderte, mit disulfid gebundene konjugate daraus. |
| US4925648A (en) | 1988-07-29 | 1990-05-15 | Immunomedics, Inc. | Detection and treatment of infectious and inflammatory lesions |
| US5601819A (en) | 1988-08-11 | 1997-02-11 | The General Hospital Corporation | Bispecific antibodies for selective immune regulation and for selective immune cell binding |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ES2096590T3 (es) | 1989-06-29 | 1997-03-16 | Medarex Inc | Reactivos biespecificos para la terapia del sida. |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US5891693A (en) | 1990-01-25 | 1999-04-06 | Alusuisse Holdings A.G. | Recombinant DNA methods vectors and host cells |
| AU667460B2 (en) | 1990-10-05 | 1996-03-28 | Medarex, Inc. | Targeted immunostimulation with bispecific reagents |
| EP0557300B1 (en) | 1990-10-29 | 1997-11-19 | Chiron Corporation | Bispecific antibodies, method of production, and uses thereof |
| IE921342A1 (en) | 1991-04-26 | 1992-11-04 | Surface Active Ltd | Novel antibodies, and methods for their use |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| EP1306095A3 (en) | 1992-03-05 | 2003-06-25 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| ATE234635T1 (de) | 1995-12-22 | 2003-04-15 | Bristol Myers Squibb Co | Verzweigte hydrazongruppen enthaltende kuppler |
| US5834597A (en) | 1996-05-20 | 1998-11-10 | Protein Design Labs, Inc. | Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same |
| US6130237A (en) | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| CA2289115A1 (en) | 1997-05-07 | 1998-11-12 | Bristol-Myers Squibb Company | Recombinant antibody-enzyme fusion proteins |
| WO2000046750A1 (en) | 1999-02-05 | 2000-08-10 | Samsung Electronics Co., Ltd. | Image texture retrieving method and apparatus thereof |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| SI1545613T1 (sl) | 2002-07-31 | 2011-11-30 | Seattle Genetics Inc | Avristatinski konjugati in njihova uporaba za zdravljenje raka avtoimunske bolezni ali infekcijskebolezni |
| WO2004050867A1 (en) * | 2002-12-02 | 2004-06-17 | Seattle Genetics, Inc. | MODIFIED L49-sFv EXHIBITING INCREASED STABILITY AND METHODS OF USE THEREOF |
| US20060160174A1 (en) | 2002-12-02 | 2006-07-20 | Mcdonagh Charlotte F | Modified l49-sfv exhibiting increased stability and methods of use thereof |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| BRPI0513959A (pt) | 2004-07-30 | 2008-05-20 | Rinat Neuroscience Corp | anticorpos dirigidos contra o peptìdeo beta-amilóide, suas composições farmacêuticas, kit e métodos de fabricação dos mesmos |
| US8871720B2 (en) | 2005-07-07 | 2014-10-28 | Seattle Genetics, Inc. | Monomethylvaline compounds having phenylalanine carboxy modifications at the C-terminus |
| JP5171621B2 (ja) | 2005-07-07 | 2013-03-27 | シアトル ジェネティックス, インコーポレイテッド | フェニルアラニン側鎖修飾をc末端に有するモノメチルバリン化合物 |
| HUE035853T2 (en) | 2005-07-18 | 2018-05-28 | Seattle Genetics Inc | Beta-glucuronide-linker-drug conjugates |
| WO2008070593A2 (en) | 2006-12-01 | 2008-06-12 | Seattle Genetics, Inc. | Variant target binding agents and uses thereof |
| RU2476441C2 (ru) | 2007-10-19 | 2013-02-27 | Сиэтл Дженетикс, Инк. | Cd19-связывающие средства и их применение |
| TW201617368A (zh) * | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗mfi2抗體及使用方法 |
| MX382582B (es) | 2015-03-18 | 2025-03-13 | Seagen Inc | Anticuerpos contra cúmulo de diferenciación 48 (cd48) y sus conjugados. |
| CR20190550A (es) * | 2017-06-05 | 2020-04-05 | Janssen Biotech Inc | Anticuerpos que se unen específicamente a pd-1 y métodos de uso |
| PL3817751T3 (pl) * | 2018-07-03 | 2025-09-08 | Fennec Pharmaceuticals, Inc. | Postacie użytkowe bezwodnego tiosiarczanu sodu |
| US20230270877A1 (en) * | 2020-11-08 | 2023-08-31 | Seagen Inc. | Combination Therapy |
-
2020
- 2020-02-03 WO PCT/US2020/016381 patent/WO2020163225A1/en not_active Ceased
- 2020-02-03 AU AU2020219732A patent/AU2020219732A1/en active Pending
- 2020-02-03 KR KR1020217027987A patent/KR20210125511A/ko active Pending
- 2020-02-03 US US16/780,711 patent/US11617798B2/en active Active
- 2020-02-03 EP EP20709016.8A patent/EP3920968A1/en active Pending
- 2020-02-03 BR BR112021015477A patent/BR112021015477A2/pt unknown
- 2020-02-03 MX MX2021009138A patent/MX2021009138A/es unknown
- 2020-02-03 JP JP2021545378A patent/JP7754715B2/ja active Active
- 2020-02-03 CN CN202080026997.1A patent/CN113710271B/zh active Active
- 2020-02-03 SG SG11202107551WA patent/SG11202107551WA/en unknown
- 2020-02-04 TW TW109103363A patent/TWI872044B/zh active
-
2021
- 2021-07-19 IL IL284974A patent/IL284974A/en unknown
-
2023
- 2023-02-21 US US18/172,123 patent/US20240033369A1/en not_active Abandoned
-
2024
- 2024-05-07 US US18/657,397 patent/US20240409658A1/en not_active Abandoned
-
2025
- 2025-02-12 JP JP2025021046A patent/JP2025072613A/ja not_active Withdrawn
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