JPWO2020161214A5 - - Google Patents

Download PDF

Info

Publication number
JPWO2020161214A5
JPWO2020161214A5 JP2021546257A JP2021546257A JPWO2020161214A5 JP WO2020161214 A5 JPWO2020161214 A5 JP WO2020161214A5 JP 2021546257 A JP2021546257 A JP 2021546257A JP 2021546257 A JP2021546257 A JP 2021546257A JP WO2020161214 A5 JPWO2020161214 A5 JP WO2020161214A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
seq
antibody
composition according
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021546257A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022523155A5 (https=
JP7597718B2 (ja
JP2022523155A (ja
Publication date
Priority claimed from EP19305173.7A external-priority patent/EP3693023A1/en
Application filed filed Critical
Priority claimed from PCT/EP2020/052932 external-priority patent/WO2020161214A1/en
Publication of JP2022523155A publication Critical patent/JP2022523155A/ja
Publication of JP2022523155A5 publication Critical patent/JP2022523155A5/ja
Publication of JPWO2020161214A5 publication Critical patent/JPWO2020161214A5/ja
Application granted granted Critical
Publication of JP7597718B2 publication Critical patent/JP7597718B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021546257A 2019-02-07 2020-02-06 肺がんを処置するための抗ceacam5イムノコンジュゲートの使用 Active JP7597718B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962802511P 2019-02-07 2019-02-07
US62/802,511 2019-02-07
EP19305173.7A EP3693023A1 (en) 2019-02-11 2019-02-11 Use of anti-ceacam5 immunoconjugates for treating lung cancer
EP19305173.7 2019-02-11
EP19305504.3 2019-04-18
EP19305504 2019-04-18
PCT/EP2020/052932 WO2020161214A1 (en) 2019-02-07 2020-02-06 Use of anti-ceacam5 immunoconjugates for treating lung cancer

Publications (4)

Publication Number Publication Date
JP2022523155A JP2022523155A (ja) 2022-04-21
JP2022523155A5 JP2022523155A5 (https=) 2023-01-26
JPWO2020161214A5 true JPWO2020161214A5 (https=) 2023-01-26
JP7597718B2 JP7597718B2 (ja) 2024-12-10

Family

ID=71947024

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021546257A Active JP7597718B2 (ja) 2019-02-07 2020-02-06 肺がんを処置するための抗ceacam5イムノコンジュゲートの使用

Country Status (14)

Country Link
US (1) US20220080053A1 (https=)
EP (1) EP3920972A1 (https=)
JP (1) JP7597718B2 (https=)
KR (1) KR20210124260A (https=)
CN (1) CN114173823A (https=)
AU (1) AU2020219405A1 (https=)
BR (1) BR112021014636A2 (https=)
CA (1) CA3129106A1 (https=)
CO (1) CO2021010032A2 (https=)
IL (1) IL285306A (https=)
MX (1) MX2021009514A (https=)
SG (1) SG11202107843WA (https=)
TW (1) TW202045539A (https=)
WO (1) WO2020161214A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE033369T2 (en) 2012-11-20 2017-11-28 Sanofi Sa Anti-ceacam5 antibodies and uses thereof
TWI851577B (zh) 2018-06-07 2024-08-11 美商思進公司 喜樹鹼結合物
WO2021214222A1 (en) * 2020-04-24 2021-10-28 Sanofi Antitumor combinations containing anti-ceacam5 antibody conjugates, trifluridine and tipiracil
US12564642B2 (en) 2020-11-10 2026-03-03 Sanofi CEACAM5 antibody-drug conjugate formulation
WO2023099682A1 (en) 2021-12-02 2023-06-08 Sanofi Ceacam5 adc–anti-pd1/pd-l1 combination therapy
EP4427763A1 (en) 2023-03-06 2024-09-11 Sanofi Antitumor combinations containing anti-ceacam5 antibody-drug conjugates, anti-vegfr-2 antibodies and anti-pd1/pd-l1 antibodies
AU2024286132A1 (en) 2023-06-05 2026-01-22 Sanofi Antitumor combinations containing anti-ceacam5 antibody-drug conjugates, anti-pd1/pd-l1 antibodies and anti-ctla4 antibodies
WO2025169012A1 (en) 2024-02-06 2025-08-14 Sanofi Methods of treating ceacam5-expressing cancers
TW202600608A (zh) * 2024-02-27 2026-01-01 美商必治妥美雅史谷比公司 抗ceacam5抗體及其用途
EP4658320A1 (en) 2024-02-27 2025-12-10 Bristol-Myers Squibb Company Anti-ceacam5 antibody drug conjugates

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4307016A (en) 1978-03-24 1981-12-22 Takeda Chemical Industries, Ltd. Demethyl maytansinoids
US4256746A (en) 1978-11-14 1981-03-17 Takeda Chemical Industries Dechloromaytansinoids, their pharmaceutical compositions and method of use
JPS55102583A (en) 1979-01-31 1980-08-05 Takeda Chem Ind Ltd 20-acyloxy-20-demethylmaytansinoid compound
JPS55162791A (en) 1979-06-05 1980-12-18 Takeda Chem Ind Ltd Antibiotic c-15003pnd and its preparation
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
JPS5645483A (en) 1979-09-19 1981-04-25 Takeda Chem Ind Ltd C-15003phm and its preparation
JPS5645485A (en) 1979-09-21 1981-04-25 Takeda Chem Ind Ltd Production of c-15003pnd
EP0028683A1 (en) 1979-09-21 1981-05-20 Takeda Chemical Industries, Ltd. Antibiotic C-15003 PHO and production thereof
WO1981001145A1 (en) 1979-10-18 1981-04-30 Univ Illinois Hydrolytic enzyme-activatible pro-drugs
WO1982001188A1 (en) 1980-10-08 1982-04-15 Takeda Chemical Industries Ltd 4,5-deoxymaytansinoide compounds and process for preparing same
US4450254A (en) 1980-11-03 1984-05-22 Standard Oil Company Impact improvement of high nitrile resins
US4315929A (en) 1981-01-27 1982-02-16 The United States Of America As Represented By The Secretary Of Agriculture Method of controlling the European corn borer with trewiasine
US4313946A (en) 1981-01-27 1982-02-02 The United States Of America As Represented By The Secretary Of Agriculture Chemotherapeutically active maytansinoids from Trewia nudiflora
JPS57192389A (en) 1981-05-20 1982-11-26 Takeda Chem Ind Ltd Novel maytansinoid
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3675588D1 (de) 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
AU597574B2 (en) 1986-03-07 1990-06-07 Massachusetts Institute Of Technology Method for enhancing glycoprotein stability
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
GB8705477D0 (en) 1987-03-09 1987-04-15 Carlton Med Prod Drug delivery systems
US4975278A (en) 1988-02-26 1990-12-04 Bristol-Myers Company Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
US5215534A (en) 1991-12-02 1993-06-01 Lawrence De Harde Safety syringe system
ES2149768T3 (es) 1992-03-25 2000-11-16 Immunogen Inc Conjugados de agentes enlazantes de celulas derivados de cc-1065.
MD1367C2 (ro) 1992-11-13 2000-11-30 Idec Pharmaceuticals Corporation Metode de tratament al limfomului celulelor B, anticorpi anti-CD20, hibridom.
US6629949B1 (en) 2000-05-08 2003-10-07 Sterling Medivations, Inc. Micro infusion drug delivery device
US6659982B2 (en) 2000-05-08 2003-12-09 Sterling Medivations, Inc. Micro infusion drug delivery device
US6333410B1 (en) 2000-08-18 2001-12-25 Immunogen, Inc. Process for the preparation and purification of thiol-containing maytansinoids
GB0308731D0 (en) 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
LT1976880T (lt) 2005-12-21 2016-10-10 Amgen Research (Munich) Gmbh Farmacinės kompozicijos, pasižyminčios atsparumu tirpiam cea
ES2673822T3 (es) 2006-07-18 2018-06-25 Sanofi Anticuerpo antagonista contra EphA2 para el tratamiento de cáncer
NZ613647A (en) * 2009-05-06 2015-02-27 Biotest Ag Uses of immunoconjugates targeting cd138
US9427531B2 (en) 2010-06-28 2016-08-30 Sanofi-Aventis Deutschland Gmbh Auto-injector
US9248242B2 (en) 2012-04-20 2016-02-02 Safety Syringes, Inc. Anti-needle stick safety device for injection device
HUE033369T2 (en) * 2012-11-20 2017-11-28 Sanofi Sa Anti-ceacam5 antibodies and uses thereof
US20140155827A1 (en) 2012-12-03 2014-06-05 Mylan, Inc. Medicament information system and method
US10669338B2 (en) * 2016-06-17 2020-06-02 Immunomedics, Inc. Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1
EP3634401A1 (en) * 2017-06-07 2020-04-15 Silverback Therapeutics, Inc. Antibody construct conjugates
WO2023099682A1 (en) * 2021-12-02 2023-06-08 Sanofi Ceacam5 adc–anti-pd1/pd-l1 combination therapy
KR20250154496A (ko) * 2023-03-01 2025-10-28 사노피 Ceacam5를 발현하는 신경내분비암을 치료하기 위한 항-ceacam5 면역접합체의 용도

Similar Documents

Publication Publication Date Title
Wang et al. Antibody–Drug Conjugates (ADCs): current and future biopharmaceuticals
JP7512361B2 (ja) Ror1抗体免疫複合体
Marei et al. Potential of antibody–drug conjugates (ADCs) for cancer therapy
Yaghoubi et al. Potential drugs used in the antibody–drug conjugate (ADC) architecture for cancer therapy
Nasiri et al. Antibody‐drug conjugates: Promising and efficient tools for targeted cancer therapy
Goldenberg et al. Antibody-drug conjugates targeting TROP-2 and incorporating SN-38: A case study of anti-TROP-2 sacituzumab govitecan
Birrer et al. Antibody-drug conjugate-based therapeutics: state of the science
Trail et al. Antibody drug conjugates for treatment of breast cancer: novel targets and diverse approaches in ADC design
Chari et al. Antibody–drug conjugates: an emerging concept in cancer therapy
JP2020525542A5 (https=)
JP7512202B2 (ja) ヒト化抗前立腺特異的膜抗原(psma)抗体薬物複合体
Mack et al. The next generation of antibody drug conjugates
AU2025226765A1 (en) Combination of antibody-drug conjugate and tubulin inhibitor
Zhou et al. Drug conjugates for the treatment of lung cancer: from drug discovery to clinical practice
JP2016512832A5 (https=)
Jackson et al. Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates: Jackson and Stover
JP2014533954A5 (https=)
JP2022513684A (ja) 抗191p4d12抗体薬物コンジュゲートを含む薬学的組成物、およびその使用方法
TW202207990A (zh) 含有α-烯醇酶抗體之藥物共軛物及其用途
JPWO2020161214A5 (https=)
D’Angelo et al. An update on antibody–drug conjugates in urothelial carcinoma: state of the art strategies and what comes next
KR20250137203A (ko) 항체 약물 접합체
KR20250154496A (ko) Ceacam5를 발현하는 신경내분비암을 치료하기 위한 항-ceacam5 면역접합체의 용도
CN117304316A (zh) 靶向cd73的纳米抗体及纳米抗体-药物偶联物、其制备方法和用途
Aesoy et al. Cyanobacterial anticancer compounds in clinical use: Lessons from the dolastatins and cryptophycins