JPWO2020160537A5 - - Google Patents
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- Publication number
- JPWO2020160537A5 JPWO2020160537A5 JP2021544801A JP2021544801A JPWO2020160537A5 JP WO2020160537 A5 JPWO2020160537 A5 JP WO2020160537A5 JP 2021544801 A JP2021544801 A JP 2021544801A JP 2021544801 A JP2021544801 A JP 2021544801A JP WO2020160537 A5 JPWO2020160537 A5 JP WO2020160537A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- unsubstituted
- deuterated
- hydrogen
- undeuterated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800239P | 2019-02-01 | 2019-02-01 | |
| US62/800,239 | 2019-02-01 | ||
| PCT/US2020/016394 WO2020160537A1 (en) | 2019-02-01 | 2020-02-03 | Bicyclic pyridine compositions and methods of using the same for cancer therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022523742A JP2022523742A (ja) | 2022-04-26 |
| JPWO2020160537A5 true JPWO2020160537A5 (US07585878-20090908-C00410.png) | 2023-02-13 |
Family
ID=71842384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021544801A Pending JP2022523742A (ja) | 2019-02-01 | 2020-02-03 | 二環式ピリジン組成物およびがんの治療にそれを使用する方法 |
Country Status (7)
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271723A (en) | 1976-11-19 | 1981-06-09 | Caterpillar Tractor Co. | Power train with an auxiliary creeper drive system |
| GB9402029D0 (en) | 1994-02-03 | 1994-03-30 | Smithkline Beecham Plc | Novel formulation |
| NZ537394A (en) | 2002-06-06 | 2006-12-22 | Boehringer Ingelheim Pharma | Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses |
| US7205308B2 (en) * | 2002-09-04 | 2007-04-17 | Schering Corporation | Trisubstituted 7-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors |
| AU2005233437A1 (en) * | 2004-04-12 | 2005-10-27 | Sankyo Company, Limited | Thienopyridine derivatives |
| US20070021927A1 (en) | 2005-07-21 | 2007-01-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Selective resonance of chemical structures |
| TW200800180A (en) | 2006-03-06 | 2008-01-01 | Wyeth Corp | Liquid and semi-solid pharmaceutical formulations and processes |
| JP2008260693A (ja) * | 2007-04-10 | 2008-10-30 | Daiichi Sankyo Co Ltd | チエノピリジン−２−カルボキサミド誘導体を含有する医薬組成物 |
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| EP2489354A1 (en) | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmaceutical formulation of B220 for topical treatment of herpes |
| UA112197C2 (uk) | 2011-09-13 | 2016-08-10 | Ігор Ронінсон | СПОСІБ ЛІКУВАННЯ ЗАХВОРЮВАНЬ АБО ПОРУШЕНЬ, СПРИЧИНЮВАНИХ ІНДУКОВАНОЮ ТРАНСКРИПЦІЙНОЮ АКТИВНІСТЮ NF-kB |
| KR20150023223A (ko) | 2012-02-02 | 2015-03-05 | 세넥스 바이오테크놀러지 인코포레이티드 | Ｃｄｋ8/ｃｄｋ19 선택성 억제제 및 암에 대한 항-전이 및 화학예방 방법에서 이들의 용도 |
| EP2914266B1 (en) * | 2012-11-01 | 2019-06-19 | University of South Carolina | Cdk8/cdk19 selective inhibitors for use in a method for treating prostate cancer |
| WO2014087240A2 (en) * | 2012-12-04 | 2014-06-12 | Dalhousie University | Compositions, methods and kits for preventing, reducing, and eliminating cancer metastasis |
| CN103012428A (zh) * | 2013-01-08 | 2013-04-03 | 中国药科大学 | 4-(五元杂环并嘧啶/吡啶取代)氨基-1H-3-吡唑甲酰胺类CDK/Aurora双重抑制剂及其用途 |
| WO2014134169A1 (en) | 2013-02-26 | 2014-09-04 | Senex Biotechnology, Inc. | Inhibitors of cdk8/19 for use in treating estrogen receptor positive breast cancer |
| CN105188705A (zh) * | 2013-03-13 | 2015-12-23 | 密歇根大学董事会 | 包含噻吩并嘧啶和噻吩并吡啶化合物的组合物及其使用方法 |
| WO2014194245A2 (en) | 2013-05-31 | 2014-12-04 | Nimbus Iris, Inc. | Cdk8 inhibitors and uses thereof |
| WO2015031228A1 (en) | 2013-08-30 | 2015-03-05 | Merck Sharp & Dohme Corp. | Oral pharmaceutical formulation of omarigliptin |
| EA030907B1 (ru) * | 2013-12-24 | 2018-10-31 | Президент Энд Феллоус Оф Гарвард Колледж | Аналоги кортистатина, их синтез и применения |
| WO2015116696A1 (en) * | 2014-01-28 | 2015-08-06 | Massachusetts Institute Of Technology | Combination therapies and methods of use thereof for treating cancer |
| US9862708B2 (en) * | 2014-02-14 | 2018-01-09 | Tempest Therapeutics, Inc. | Pyrazolone compounds and uses thereof |
| CA2959762A1 (en) | 2014-06-10 | 2016-02-04 | University Of South Carolina | Methods and compositions for treatment of her-positive cancers |
| WO2016009076A1 (en) * | 2014-07-17 | 2016-01-21 | Merck Patent Gmbh | Novel naphthryidines and isoquinolines and their use as cdk8/19 inhibitors |
| WO2016041618A1 (en) * | 2014-09-15 | 2016-03-24 | Merck Patent Gmbh | Substituted indazoles and related heterocycles |
| US20210322651A1 (en) | 2014-12-18 | 2021-10-21 | Senex Biotechnology, Inc. | Suppression of neointimal formation following vascular surgeru using cdk8 inhibitors |
| CA3002495A1 (en) * | 2015-11-03 | 2017-05-11 | Lu License Ab | Compounds for treatment of hypoproliferative disorders |
| US11014906B2 (en) | 2018-08-21 | 2021-05-25 | University Of South Carolina | Quinoline-based compounds and methods of inhibiting CDK8/19 |
| US20220226343A1 (en) * | 2019-05-21 | 2022-07-21 | University Of South Carolina | 3-amino-4-[4-[4 (dimethylcarbamoyl) phenyl]-1,4-diazepan-1-yl]thieno[2,3-b]pyridine-2-carboxamide for use in cancer therapy and formulations comprising the same |
-
2020
- 2020-02-03 EP EP20749196.0A patent/EP3917523A4/en active Pending
- 2020-02-03 CA CA3128377A patent/CA3128377A1/en active Pending
- 2020-02-03 WO PCT/US2020/016394 patent/WO2020160537A1/en unknown
- 2020-02-03 US US17/427,487 patent/US11572369B2/en active Active
- 2020-02-03 AU AU2020216498A patent/AU2020216498A1/en active Pending
- 2020-02-03 JP JP2021544801A patent/JP2022523742A/ja active Pending
- 2020-02-03 CN CN202080026293.4A patent/CN113677341A/zh active Pending
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