JPWO2020021333A5

JPWO2020021333A5 -

Info

Publication number: JPWO2020021333A5
Application number: JP2021504208A
Authority: JP
Publication date: 2022-08-25

Claims

An intraluminal device comprising an elongated body formed of a plurality of wires, the intraluminal device comprising:
a first region in which the plurality of wires are twisted to form a first cable;
a second region distal to the first region and having the plurality of wires interwoven to form an expandable mesh segment configured to trap clots;
a third region distal to said second region and forming a distal tip of said elongated body, said plurality of wires in said third region being twisted to form a second cable; and a third region,
An intraluminal device, wherein at least one wire of the plurality of wires extends continuously from the first region to the distal tip of the elongate body.

The expandable mesh segment comprises:
at least one expandable filter segment having said plurality of wires woven into a first weave pattern, said first weave pattern comprising openings formed between two or more wires; at least one expandable filter segment having therein;
at least one expandable clot entrapment zone in which the plurality of wires are woven to form a second weave pattern, the second weave pattern being different from the first weave pattern and having two or more at least one expandable clot entrapment zone having an opening therein formed between the wires of
2. The intraluminal device of claim 1, wherein in an expanded configuration, the opening of the at least one clot trapping zone is larger than the opening of the at least one filter segment.

The plurality of wires within the at least one clot entrapment zone are grouped into a plurality of wire groups within the at least one clot entrapment zone, each wire group of the plurality of wire groups comprising at least two wires. to form an intertwined wire combination.

4. The intraluminal device of claim 3, wherein the opening of the at least one clot entrapment zone is formed between at least two of the intertwined wire combinations.

4. The intraluminal device of claim 3, wherein each wire group of the plurality of wire groups includes 1 wire, 2 wires, 3 wires, or 4 wires.

3. The intraluminal device of claim 2, wherein the at least one expandable filter segment is configured to trap clots smaller than the at least one expandable clot trapping zone.

The expandable mesh segment comprises:
a first filter segment;
a second filter segment distal to the first filter segment;
a first clot trapping zone positioned between the first filter segment and the first region of the intraluminal device;
3. The intraluminal device of claim 2, comprising a second clot trapping zone positioned between the second filter segment and the third region of the intraluminal device.

3. The intraluminal device of claim 1, wherein the plurality of wires comprises at least one of a set of 8 wires, 10 wires, and 12 wires.

The intraluminal device of Claim 1, wherein said at least one wire has a diameter between 40 microns and 200 microns.

10. The intraluminal device of claim 9, wherein said at least one wire has a diameter between 50 microns and 75 microns.

further comprising at least one radiopaque marker positioned at a point along the elongate body, the point along the elongate body being a point distal to the second region and a point distal to the second region; 2. The intraluminal device of claim 1, which is at least one of the proximal points.

10. The first region of the intraluminal device, the second region of the intraluminal device, and the third region of the intraluminal device are formed as one unitary structure. 2. The intraluminal device according to 1.

A method of manufacturing an intraluminal device comprising an elongate body formed of a plurality of wires, the method comprising:
twisting a plurality of wires over a first segment of a mandrel to form a first cable of the elongated body;
weaving the plurality of wires over a second segment of the mandrel to form an expandable mesh segment of the elongated body configured to trap clots;
twisting the plurality of wires over a third segment of the mandrel to form a second cable of the elongated body;
The method, wherein the second segment of the mandrel is positioned between the first segment of the mandrel and the third segment of the mandrel.

14. The method of claim 13, further comprising heat treating the expandable mesh segment.

14. The method of claim 13, wherein the second segment of the mandrel has a larger diameter than the first segment of the mandrel and the third segment of the mandrel.

14. The method of claim 13, wherein the plurality of wires comprises at least one of a set of 8 wires, 10 wires, and 12 wires.

14. The method of claim 13, wherein at least one wire of said plurality of wires has a diameter between 40 microns and 200 microns.

18. The method of claim 17, wherein at least one wire of said plurality of wires has a diameter between 50 microns and 75 microns.

14. The method of claim 13, wherein the first cable of the elongate body, the expandable mesh segment of the elongate body, and the second cable of the elongate body are formed as one unitary structure. .