JPWO2020002620A5 - - Google Patents
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- JPWO2020002620A5 JPWO2020002620A5 JP2020570706A JP2020570706A JPWO2020002620A5 JP WO2020002620 A5 JPWO2020002620 A5 JP WO2020002620A5 JP 2020570706 A JP2020570706 A JP 2020570706A JP 2020570706 A JP2020570706 A JP 2020570706A JP WO2020002620 A5 JPWO2020002620 A5 JP WO2020002620A5
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Claims (18)
超音波撮像装置と通信し、被検体の解剖学的構造の超音波画像を受信するように構成される通信インターフェースと、
前記通信インターフェースと通信するプロセッサであって、
前記超音波画像に予測ネットワークを適用して、
前記被検体の解剖学的構造における潜在的な悪性腫瘍の複数の位置を識別し、
前記潜在的な悪性腫瘍の複数の位置における複数の悪性腫瘍尤度を決定し、
生検を避けるために前記被検体の解剖学的構造のクリティカルな領域を識別し、
前記潜在的な悪性腫瘍の複数の位置における前記複数の悪性腫瘍尤度に対する複数の信頼レベルを決定し、
前記プロセッサと通信するディスプレイに、前記潜在的な悪性腫瘍の複数の位置、前記複数の悪性腫瘍尤度、前記複数の信頼レベル、及び前記超音波画像上の前記クリティカルな領域のインジケーションのオーバーレイを出力して、前記被検体の解剖学的構造に対する生検決定をガイドする
ように構成されるプロセッサと
を有する、超音波撮像システム。 It is an ultrasonic imaging system
A communication interface configured to communicate with the ultrasound imager and receive an ultrasound image of the anatomy of the subject,
A processor that communicates with the communication interface.
Applying a predictive network to the ultrasound image,
Identifying multiple locations of potential malignancies in the subject's anatomy
To determine the likelihood of multiple malignancies at multiple locations of the potential malignancies,
To avoid biopsy, identify critical areas of the subject's anatomy and
Determine multiple levels of confidence for the multiple malignant tumor likelihood at multiple locations of the potential malignant tumor.
A display communicating with the processor overlays the location of the potential malignancies , the malignancy likelihood , the confidence levels, and the indication of the critical area on the ultrasound image. An ultrasound imaging system comprising a processor configured to output and guide a biopsy decision on the anatomical structure of the subject.
前記超音波画像の第2のインスタンス上の前記潜在的な悪性腫瘍の複数の位置における前記複数の信頼レベルのインジケーションのオーバーレイを含む第2のマップと With a second map containing overlays of the plurality of confidence levels of indication at multiple locations of the potential malignancies on the second instance of the ultrasound image.
を表示するように構成される前記ディスプレイThe display configured to display
を更に有する、請求項1に記載のシステム。The system according to claim 1, further comprising.
前記潜在的な悪性腫瘍の複数の位置、前記クリティカルな領域、又は前記被検体の解剖学的構造における標的生検位置の少なくとも1つに基づいて、前記被検体の解剖学的構造上で生検を実施するための生検針経路を決定する A biopsy on the subject's anatomy based on at least one of the potential malignancies, the critical region, or the target biopsy location in the subject's anatomy. Determine the biopsy route to perform
ように構成される、請求項1に記載のシステム 。The system according to claim 1, wherein the system is configured as follows.
前記複数の潜在的な悪性腫瘍の複数の位置における前記複数の悪性腫瘍尤度又は前記複数の悪性腫瘍尤度に対する前記複数の信頼レベルのうちの少なくとも1つに基づいて、前記被検体の解剖学的構造に対する標的生検位置を決定するように構成され、 Anatomy of the subject based on at least one of the plurality of confidence levels for the plurality of malignant tumor likelihood or the plurality of malignant tumor likelihood at multiple locations of the plurality of potential malignancies. Configured to determine the target biopsy position for the structure,
前記生検針経路は、前記決定される標的生検位置に基づいてさらに決定される、 The biopsy path is further determined based on the determined target biopsy position.
請求項4に記載のシステム。The system according to claim 4.
を更に有する、請求項4に記載のシステム。4. The system according to claim 4.
ように更に構成される、請求項4に記載のシステム。The system according to claim 4, further configured as described above.
前記クリティカルな領域が前記被検体の解剖学的構造に向けられる生検針の軌道経路に沿っていることを決定し、 Determined that the critical region is along the orbital path of the biopsy needle directed to the subject's anatomy.
前記生検針と前記クリティカルな領域との間の潜在的な衝突のインジケーションを前記ディスプレイに出力する Output to the display the indication of a potential collision between the biopsy needle and the critical area.
ように更に構成される、請求項4に記載のシステム。The system according to claim 4, further configured as described above.
前記予測ネットワークを前記超音波画像に適用して、前記生検を実行するために前記第1の撮像位置から第2の撮像位置まで前記超音波撮像装置を再配置するための動き制御構成を決定し、 The prediction network is applied to the ultrasound image to determine a motion control configuration for rearranging the ultrasound imager from the first imaging position to the second imaging position to perform the biopsy. death,
前記動き制御構成に基づいて前記超音波撮像装置を再配置するための視覚的インジケータを前記ディスプレイに出力する A visual indicator for rearranging the ultrasonic image pickup device based on the motion control configuration is output to the display.
ように更に構成される、請求項4に記載のシステム。The system according to claim 4, further configured as described above.
試験被検体の解剖学的構造の複数の試験超音波画像、試験被検体の解剖学的構造に実施される生検の生検位置、及び前記生検位置で実施される前記生検の病理結果を提供すること、及び Multiple test ultrasound images of the anatomy of the test subject, the biopsy position of the biopsy performed on the anatomy of the test subject, and the pathological results of the biopsy performed at the biopsy position. To provide, and
前記生検位置及び前記病理結果に基づいて前記複数の試験超音波画像のピクセルにスコアを割り当てること Assigning a score to the pixels of the plurality of test ultrasound images based on the biopsy position and the pathological result.
によって訓練される、請求項1に記載のシステム。The system according to claim 1, which is trained by.
前記潜在的な悪性腫瘍の複数の位置及び前記複数の悪性腫瘍尤度に基づいて決定される生検のための標的生検位置、又は Target biopsy positions for biopsy determined based on multiple locations of the potential malignancies and the multiple locations of the malignant tumors, or
前記生検の病理学的結果 Pathological results of the biopsy
の少なくとも1つに基づいて前記予測ネットワークを更新するように更に構成される、請求項1に記載のシステム。The system of claim 1, further configured to update said predictive network based on at least one of the above.
被検体の解剖学的構造の超音波画像を超音波撮像装置から受信するステップと、 The step of receiving an ultrasonic image of the anatomical structure of the subject from the ultrasonic image pickup device,
前記超音波画像に予測ネットワークを適用して、 Applying a predictive network to the ultrasound image,
前記被検体の解剖学的構造における潜在的な悪性腫瘍の複数の位置を識別し、 Identifying multiple locations of potential malignancies in the subject's anatomy
前記潜在的な悪性腫瘍の複数の位置における複数の悪性腫瘍尤度を決定し、 To determine the likelihood of multiple malignancies at multiple locations of the potential malignancies,
生検を避けるために前記被検体の解剖学的構造のクリティカルな領域を識別し、 To avoid biopsy, identify critical areas of the subject's anatomy and
前記潜在的な悪性腫瘍の複数の位置における前記複数の悪性腫瘍尤度に対する複数の信頼レベルを決定する Determine multiple levels of confidence for the multiple malignant tumor likelihood at multiple locations of the potential malignant tumor.
ステップと、Steps and
前記潜在的な悪性腫瘍の複数の位置、前記複数の悪性腫瘍尤度、前記複数の信頼レベル、又は前記超音波画像上の前記クリティカルな領域のインジケーションのオーバーレイをディスプレイによって表示して、前記被検体の解剖学的構造に対する生検決定をガイドするステップと The display displays an overlay of an indication of the critical region on the ultrasound image of the potential malignancies at multiple locations, the malignant tumor likelihood, the confidence levels, or the subject. Steps to guide biopsy decisions on the anatomical structure of the specimen
を有する、方法。The method.
前記超音波画像の第1のインスタンス上のクリティカルな領域、前記潜在的な悪性腫瘍の複数の位置、及び前記複数の悪性腫瘍尤度のインジケーションのオーバーレイを含む第1のマップを表示するステップと、 With the step of displaying a first map containing a critical area on the first instance of the ultrasound image, multiple locations of the potential malignancies, and an overlay of the indications of the plurality of malignant tumor likelihood. ,
前記潜在的な悪性腫瘍の複数の位置に対応する前記超音波画像の第2のインスタンス上の複数の信頼レベルのインジケーションのオーバーレイを含む第2のマップを表示するステップと With the step of displaying a second map containing overlays of multiple confidence level indications on the second instance of the ultrasound image corresponding to multiple locations of the potential malignancies.
を含む、請求項14に記載の方法。14. The method of claim 14.
前記潜在的な悪性腫瘍の複数の位置、前記クリティカルな領域、又は前記被検体の解剖学的構造の前記標的生検位置の少なくとも1つに基づいて前記生検を実施するための生検針経路を決定するステップと、 A biopsy path for performing the biopsy based on at least one of the potential malignant tumor locations, the critical region, or the target biopsy location of the subject's anatomy. Steps to decide and
前記ディスプレイによって、前記決定される生検針経路を第1のマップ上にオーバーレイとして表示するステップと With the step of displaying the determined biopsy path as an overlay on the first map by the display.
を更に有する、請求項15に記載の方法。15. The method of claim 15.
前記ディスプレイによって、前記生検針と前記クリティカルな領域との間の潜在的な衝突のインジケーションを表示するステップと With the step of showing the indication of a potential collision between the biopsy needle and the critical area by the display.
を更に有する、請求項16に記載の方法。16. The method of claim 16.
前記予測ネットワークを前記超音波画像に適用して、前記第1の撮像位置から前記生検を実行するための第2の撮像位置に前記超音波撮像装置を再配置するための動き制御構成を決定するステップと、 The prediction network is applied to the ultrasound image to determine a motion control configuration for relocating the ultrasound imager from the first imaging position to the second imaging position for performing the biopsy. Steps to do and
前記ディスプレイによって、前記動き制御構成に基づいて前記超音波撮像装置を再配置するための視覚的インジケータを表示するステップと With the step of displaying a visual indicator for rearranging the ultrasonic image pickup device based on the motion control configuration by the display.
を更に有する、請求項16に記載の方法。16. The method of claim 16.
Applications Claiming Priority (5)
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US201862691688P | 2018-06-29 | 2018-06-29 | |
US62/691,688 | 2018-06-29 | ||
US201862693808P | 2018-07-03 | 2018-07-03 | |
US62/693,808 | 2018-07-03 | ||
PCT/EP2019/067366 WO2020002620A1 (en) | 2018-06-29 | 2019-06-28 | Biopsy prediction and guidance with ultrasound imaging and associated devices, systems, and methods |
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JP2021528158A JP2021528158A (en) | 2021-10-21 |
JPWO2020002620A5 true JPWO2020002620A5 (en) | 2022-05-09 |
JP7357015B2 JP7357015B2 (en) | 2023-10-05 |
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US (1) | US20210259660A1 (en) |
EP (1) | EP3813676B1 (en) |
JP (1) | JP7357015B2 (en) |
CN (1) | CN112334076A (en) |
WO (1) | WO2020002620A1 (en) |
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- 2019-06-28 WO PCT/EP2019/067366 patent/WO2020002620A1/en active Application Filing
- 2019-06-28 CN CN201980044030.3A patent/CN112334076A/en active Pending
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