JPWO2019178561A5 - - Google Patents
Download PDFInfo
- Publication number
- JPWO2019178561A5 JPWO2019178561A5 JP2020549687A JP2020549687A JPWO2019178561A5 JP WO2019178561 A5 JPWO2019178561 A5 JP WO2019178561A5 JP 2020549687 A JP2020549687 A JP 2020549687A JP 2020549687 A JP2020549687 A JP 2020549687A JP WO2019178561 A5 JPWO2019178561 A5 JP WO2019178561A5
- Authority
- JP
- Japan
- Prior art keywords
- image
- test cell
- cell
- machine learning
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cells Anatomy 0.000 claims description 112
- 238000010801 machine learning Methods 0.000 claims description 32
- 238000002835 absorbance Methods 0.000 claims description 12
- 230000001537 neural Effects 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 10
- 210000001671 Embryonic Stem Cells Anatomy 0.000 claims description 6
- 210000004263 Induced Pluripotent Stem Cells Anatomy 0.000 claims description 6
- 210000002901 Mesenchymal Stem Cells Anatomy 0.000 claims description 6
- 210000001178 Neural Stem Cells Anatomy 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 210000003958 Hematopoietic Stem Cells Anatomy 0.000 claims description 4
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 claims description 4
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims description 4
- 238000001000 micrograph Methods 0.000 claims description 4
- 210000000130 stem cell Anatomy 0.000 claims description 4
- 206010070863 Toxicity to various agents Diseases 0.000 claims description 2
- 210000003995 blood forming stem cell Anatomy 0.000 claims description 2
- 201000011510 cancer Diseases 0.000 claims description 2
- 230000003915 cell function Effects 0.000 claims description 2
- 230000001413 cellular Effects 0.000 claims description 2
- 239000003086 colorant Substances 0.000 claims description 2
- 201000010099 disease Diseases 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 238000007876 drug discovery Methods 0.000 claims description 2
- 229940079593 drugs Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 238000002073 fluorescence micrograph Methods 0.000 claims description 2
- 230000003834 intracellular Effects 0.000 claims description 2
- 238000000386 microscopy Methods 0.000 claims description 2
- 239000000790 retinal pigment Substances 0.000 claims description 2
- 230000028327 secretion Effects 0.000 claims description 2
- 210000001519 tissues Anatomy 0.000 claims description 2
- 230000001766 physiological effect Effects 0.000 claims 1
- 230000004048 modification Effects 0.000 description 2
- 238000006011 modification reaction Methods 0.000 description 2
- 230000000875 corresponding Effects 0.000 description 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862644175P | 2018-03-16 | 2018-03-16 | |
US62/644,175 | 2018-03-16 | ||
PCT/US2019/022611 WO2019178561A2 (fr) | 2018-03-16 | 2019-03-15 | Utilisation de réseaux neuronaux et/ou d'apprentissage machine pour valider des cellules souches et leurs dérivés pour une utilisation dans la thérapie cellulaire, la découverte de médicaments et le diagnostic |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2021515586A JP2021515586A (ja) | 2021-06-24 |
JPWO2019178561A5 true JPWO2019178561A5 (fr) | 2022-03-22 |
Family
ID=65995869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020549687A Pending JP2021515586A (ja) | 2018-03-16 | 2019-03-15 | 細胞療法、創薬および診断法における使用のための幹細胞およびその誘導体を検証するために機械学習および/またはニューラルネットワークを使用すること |
Country Status (6)
Country | Link |
---|---|
US (2) | US11531844B2 (fr) |
EP (1) | EP3766000A2 (fr) |
JP (1) | JP2021515586A (fr) |
AU (1) | AU2019236297B2 (fr) |
CA (1) | CA3094078A1 (fr) |
WO (1) | WO2019178561A2 (fr) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3675835A4 (fr) | 2017-08-28 | 2021-06-09 | Matthias Wagner | Systèmes et procédés d'administration intracellulaire activés par laser microfluidiques |
US11808760B1 (en) * | 2019-02-14 | 2023-11-07 | Curi Bio, Inc. | System and methods for in vitro structural toxicity testing |
JP7496364B2 (ja) | 2019-02-20 | 2024-06-06 | ブルーロック セラピューティクス エルピー | 人工知能を使用した大きな画像データセット中の目的の細胞の検出 |
IL287060B2 (en) | 2019-04-11 | 2024-08-01 | Agilent Technologies Inc | Deep learning based training of momentary segmentation through regression layers |
EP3956649A4 (fr) * | 2019-04-19 | 2023-01-04 | Becton, Dickinson and Company | Sous-échantillonnage de données d'événement cytométrique en flux |
EP3963508B1 (fr) * | 2019-05-03 | 2024-09-18 | Huron Technologies International Inc. | Système de diagnostic d'images, et ses procédés d'exploitation |
WO2020237185A1 (fr) * | 2019-05-23 | 2020-11-26 | Icahn School Of Medicine At Mount Sinai | Systèmes et procédés pour entraîner un détecteur d'objets cellulaires |
SG11202112551SA (en) * | 2019-05-31 | 2021-12-30 | Paige Ai Inc | Systems and methods for processing images of slides to automatically prioritize the processed images of slides for digital pathology |
JP7526211B2 (ja) * | 2019-06-07 | 2024-07-31 | ライカ マイクロシステムズ シーエムエス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 生物学関連のデータを処理するためのシステムおよび方法、顕微鏡を制御するためのシステムおよび方法ならびに顕微鏡 |
JP7342950B2 (ja) * | 2019-07-18 | 2023-09-12 | 株式会社島津製作所 | 細胞画像解析方法および細胞画像解析装置 |
US11288806B2 (en) | 2019-09-30 | 2022-03-29 | Siemens Healthcare Gmbh | Protocol-aware tissue segmentation in medical imaging |
EP3805986A1 (fr) * | 2019-10-07 | 2021-04-14 | Robert Bosch GmbH | Procédé de mesure de la performance des limites d'un réseau de segmentation sémantique |
CN110838116B (zh) * | 2019-11-14 | 2023-01-03 | 上海联影医疗科技股份有限公司 | 医学图像采集方法、装置、设备和计算机可读存储介质 |
US10902551B1 (en) * | 2019-12-17 | 2021-01-26 | X Development Llc | True positive transplant |
JP2021099234A (ja) * | 2019-12-20 | 2021-07-01 | 横河電機株式会社 | 新規創薬スクリーニング方法 |
JP2023508905A (ja) * | 2019-12-20 | 2023-03-06 | ジェネンテック, インコーポレイテッド | 畳み込みニューラルネットワークによる細胞株開発画像特性評価 |
CN111402320A (zh) * | 2020-03-17 | 2020-07-10 | 北京和众视野科技有限公司 | 一种基于深度学习的纤维截面直径检测方法 |
CN111443165B (zh) * | 2020-03-27 | 2021-06-11 | 华中科技大学 | 一种基于气体传感器与深度学习的气味识别方法 |
CN111709908B (zh) * | 2020-05-09 | 2024-03-26 | 上海健康医学院 | 一种基于深度学习的氦泡分割计数方法 |
US20230221239A1 (en) * | 2020-06-03 | 2023-07-13 | Case Western Reserve University | Classification of blood cells |
JP7427289B2 (ja) * | 2020-06-17 | 2024-02-05 | Milk.株式会社 | 生体細胞解析装置、生体細胞解析システム、生体細胞解析プログラムおよび生体細胞解析方法 |
WO2022031765A1 (fr) * | 2020-08-03 | 2022-02-10 | Emgenisys, Inc. | Évaluation d'embryons basée sur une vidéo en temps réel |
US11385292B2 (en) * | 2020-09-10 | 2022-07-12 | Volkswagen Aktiengesellschaft | Battery materials screening |
CN112198799B (zh) * | 2020-10-28 | 2021-05-14 | 北京交通大学 | 一种基于深度学习的高速列车停车控制方法及系统 |
KR102497003B1 (ko) * | 2020-11-30 | 2023-02-06 | 재단법인대구경북과학기술원 | 약물 평가 방법 및 장치 |
US20220277327A1 (en) * | 2021-02-26 | 2022-09-01 | Capital One Services, Llc | Computer-based systems for data distribution allocation utilizing machine learning models and methods of use thereof |
US11866735B2 (en) | 2021-03-07 | 2024-01-09 | Cellino Biotech, Inc. | Platforms and systems for automated cell culture |
TWI790572B (zh) | 2021-03-19 | 2023-01-21 | 宏碁智醫股份有限公司 | 影像相關的檢測方法及檢測裝置 |
CN113177574B (zh) * | 2021-03-19 | 2022-08-16 | 华中科技大学 | 用于材料表征图像分析的视觉模型及其分析方法 |
US20220309810A1 (en) * | 2021-03-26 | 2022-09-29 | Howard University | Method for the detection, segmentation and morphological mapping on neural cell images of the whole brain |
US20220358646A1 (en) * | 2021-05-04 | 2022-11-10 | Q-State Biosciences, Inc. | Cell activity machine learning |
CN113283353B (zh) * | 2021-05-31 | 2022-04-01 | 创芯国际生物科技(广州)有限公司 | 一种基于显微图像的类器官细胞计数方法及系统 |
GB2607604A (en) * | 2021-06-08 | 2022-12-14 | Solentim Ltd | Brightfield and fluorescence image comparison |
DE102021115588A1 (de) * | 2021-06-16 | 2022-12-22 | Carl Zeiss Meditec Ag | Multi-task-lernen von weisslichtaufnahmen für ein operationsmikroskop |
CN113723442B (zh) * | 2021-07-08 | 2024-02-20 | 华中科技大学 | 一种电子鼻气体识别方法、系统、电子设备及存储介质 |
WO2023003993A1 (fr) * | 2021-07-21 | 2023-01-26 | Coriell Institute For Medical Research | Classification sans étiquette de cellules par analyse d'image et apprentissage automatique |
US11995842B2 (en) | 2021-07-22 | 2024-05-28 | X Development Llc | Segmentation to improve chemical analysis |
US12033329B2 (en) | 2021-07-22 | 2024-07-09 | X Development Llc | Sample segmentation |
CN113505849B (zh) * | 2021-07-27 | 2023-09-19 | 电子科技大学 | 一种基于对比学习的多层网络聚类方法 |
CN113604544B (zh) * | 2021-08-03 | 2023-03-10 | 北京大学口腔医学院 | 一种生物材料功能预测评价方法 |
US11931737B2 (en) | 2021-09-02 | 2024-03-19 | Cellino Biotech, Inc. | Platforms and systems for automated cell culture |
CN114202690B (zh) * | 2021-12-09 | 2024-04-12 | 东北林业大学 | 以混合多层感知器为基础的多尺度网络分析方法 |
WO2023177923A1 (fr) * | 2022-03-18 | 2023-09-21 | University Of South Florida | Classification de prolifération cellulaire globale sur la base d'un apprentissage profond |
US20230343118A1 (en) * | 2022-04-21 | 2023-10-26 | FUJIFILM Cellular Dynamics, Inc. | Automated cell culture analysis and classification and detection |
WO2023221951A2 (fr) * | 2022-05-14 | 2023-11-23 | 北京大学 | Différenciation cellulaire sur la base d'un apprentissage automatique utilisant des images cellulaires dynamiques |
US20230409960A1 (en) * | 2022-06-21 | 2023-12-21 | Recursion Pharmaceuticals, Inc. | Image embeddings via deep learning and adaptive batch normalization |
WO2024039770A2 (fr) | 2022-08-17 | 2024-02-22 | Xilis, Inc. | Dosages de médicament de micro-organosphère basés sur l'imagerie |
CN115272342B (zh) * | 2022-09-29 | 2023-02-17 | 深圳大学 | 基于明场图像的细胞分化程度评估方法、存储介质及系统 |
US20240221944A1 (en) * | 2022-12-29 | 2024-07-04 | Idexx Laboratories, Inc. | Methods and Systems for Providing Diagnosis Assistance Using Similarity Search Bi-Directional Communications to Resolve Indeterminate Diagnoses |
WO2024186986A1 (fr) * | 2023-03-07 | 2024-09-12 | Virginia Commonwealth University | Modèle de régression à auto-optimisation |
CN117953977B (zh) * | 2024-03-26 | 2024-06-11 | 广东美赛尔细胞生物科技有限公司 | 一种重组间充质干细胞培养控制方法及系统 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2485602C (fr) * | 2002-05-14 | 2013-10-01 | Amersham Biosciences Niagara, Inc. | Systeme et procede de criblage automatique et rapide de cellules |
JP5181385B2 (ja) * | 2007-08-16 | 2013-04-10 | 国立大学法人名古屋大学 | 細胞の品質を予測する予測モデルの構築法、予測モデルの構築用ブログラム、該プログラムを記録した記録媒体、予測モデルの構築用装置 |
JP5816415B2 (ja) * | 2010-04-23 | 2015-11-18 | 国立大学法人名古屋大学 | 細胞評価装置、インキュベータ、プログラム、および、培養方法 |
-
2019
- 2019-03-15 AU AU2019236297A patent/AU2019236297B2/en active Active
- 2019-03-15 EP EP19714930.5A patent/EP3766000A2/fr active Pending
- 2019-03-15 WO PCT/US2019/022611 patent/WO2019178561A2/fr active Application Filing
- 2019-03-15 JP JP2020549687A patent/JP2021515586A/ja active Pending
- 2019-03-15 US US16/981,531 patent/US11531844B2/en active Active
- 2019-03-15 CA CA3094078A patent/CA3094078A1/fr active Pending
-
2022
- 2022-11-09 US US17/983,963 patent/US12020494B2/en active Active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPWO2019178561A5 (fr) | ||
Schaub et al. | Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy | |
US12020494B2 (en) | Using machine learning and/or neural networks to validate stem cells and their derivatives (2-D cells and 3-D tissues) for use in cell therapy and tissue engineered products | |
US10886008B2 (en) | Methods and systems for determining the biological age of samples | |
Meijering et al. | Tracking in cell and developmental biology | |
Dong et al. | Deep learning for automatic cell detection in wide-field microscopy zebrafish images | |
US20200372652A1 (en) | Calculation device, calculation program, and calculation method | |
Du et al. | Organoids revealed: morphological analysis of the profound next generation in-vitro model with artificial intelligence | |
Yang et al. | A live-cell image-based machine learning strategy for reducing variability in PSC differentiation systems | |
US11645859B2 (en) | Analysis device, analysis method, analysis program and display device | |
Wang et al. | OC_Finder: osteoclast segmentation, counting, and classification using watershed and deep learning | |
WO2018066039A1 (fr) | Dispositif d'analyse, procédé d'analyse et programme | |
WO2018193612A1 (fr) | Dispositif de calcul de corrélation, procédé de calcul de corrélation, et programme de calcul de corrélation | |
Doan et al. | Label-free assessment of red blood cell storage lesions by deep learning | |
Zhang et al. | 4D Light-sheet Imaging of Zebrafish Cardiac Contraction | |
Kwok et al. | Single-cell transcriptomics of dynamic cell behaviors | |
Otesteanu et al. | Machine learning for predicting Plasmodium liver stage development in vitro using microscopy imaging | |
Medici et al. | The FlyCatwalk: a high-throughput feature-based sorting system for artificial selection in Drosophila | |
JP2020124220A (ja) | 画像処理装置 | |
ISAKA et al. | Development of a web based image annotation tool for lung immunofluorescent confocal images | |
Kwok et al. | Single-cell transcriptomics of a dynamic cell behavior in murine airways | |
Wang et al. | OC_Finder: A deep learning-based software for osteoclast segmentation, counting, and classification | |
de Kraker et al. | SpecSeg: cross spectral power-based segmentation of neurons and neurites in chronic calcium imaging datasets | |
Habibalahi et al. | Automated pancreatic islet viability assessment for transplantation using bright-field deep morphological signature | |
Nguyen et al. | Utilizing convolutional neural networks for discriminating cancer and stromal cells in three-dimensional cell culture images with nuclei counterstain |