JPWO2019177683A5 - - Google Patents

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JPWO2019177683A5
JPWO2019177683A5 JP2020546921A JP2020546921A JPWO2019177683A5 JP WO2019177683 A5 JPWO2019177683 A5 JP WO2019177683A5 JP 2020546921 A JP2020546921 A JP 2020546921A JP 2020546921 A JP2020546921 A JP 2020546921A JP WO2019177683 A5 JPWO2019177683 A5 JP WO2019177683A5
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bubbles
manifold
bubble
dressing
sheet
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Priority claimed from PCT/US2019/013150 external-priority patent/WO2019177683A1/en
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Publication of JPWO2019177683A5 publication Critical patent/JPWO2019177683A5/ja
Priority to JP2023177433A priority Critical patent/JP2024001218A/en
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Claims (46)

腹部組織部位を治療するためのシステムにおいて、
液体不透過性層と複数のバブルとを備える組織インターフェースと、
前記組織インターフェース及び前記腹部組織部位の周囲に流体シールを形成するように適合されたカバーと
前記組織インターフェースに流体的に接続されるように適合された陰圧源と
を備えることを特徴とするシステム。 In a system for treating abdominal tissue sites
A tissue interface with a liquid impermeable layer and multiple bubbles,
A system comprising a cover adapted to form a fluid seal around the tissue interface and the abdominal tissue site and a negative pressure source adapted to be fluidly connected to the tissue interface. .. 請求項１に記載のシステムにおいて、前記複数のバブルがブリスタを含むことを特徴とするシステム。 The system according to claim 1, wherein the plurality of bubbles include a blister. 請求項１に記載のシステムにおいて、前記複数のバブルが、流体を収容する独立気泡を含むことを特徴とするシステム。 The system according to claim 1, wherein the plurality of bubbles include closed bubbles containing a fluid. 請求項１に記載のシステムにおいて、前記組織インターフェースの前記液体不透過性層が、前記バブル間に位置決めされた窓をさらに備えることを特徴とするシステム。 The system according to claim 1, wherein the liquid impermeable layer of the tissue interface further comprises a window positioned between the bubbles. 請求項１に記載のシステムにおいて、前記複数のバブルの各々が、約１ｍｍ～５ｍｍの直径を有することを特徴とするシステム。 The system according to claim 1, wherein each of the plurality of bubbles has a diameter of about 1 mm to 5 mm. 請求項１に記載のシステムにおいて、前記複数のバブルの各々が、約１．５ｍｍ～３ｍｍの直径を有することを特徴とするシステム。 The system according to claim 1, wherein each of the plurality of bubbles has a diameter of about 1.5 mm to 3 mm. 請求項１に記載のシステムにおいて、前記複数のバブルの各々が、約１ｍｍ～５ｍｍの高さを有することを特徴とするシステム。 The system according to claim 1, wherein each of the plurality of bubbles has a height of about 1 mm to 5 mm. 請求項１に記載のシステムにおいて、前記組織インターフェースの前記液体不透過性層が、約５０μｍ～１５０μｍの厚さを有することを特徴とするシステム。 The system according to claim 1, wherein the liquid impermeable layer of the tissue interface has a thickness of about 50 μm to 150 μm. 請求項１に記載のシステムにおいて、前記組織インターフェースの前記液体不透過性層がポリウレタンフィルムを含むことを特徴とするシステム。 The system according to claim 1, wherein the liquid impermeable layer of the tissue interface comprises a polyurethane film. 請求項１に記載のシステムにおいて、前記バブルが、半球形状、球形状、円錐形状、円筒形状、卵形状、及び立方体形状の何れか１つである体積形状を有することを特徴とするシステム。 The system according to claim 1, wherein the bubble has a volumetric shape which is any one of a hemispherical shape, a spherical shape, a conical shape, a cylindrical shape, an egg shape, and a cubic shape. 請求項１に記載のシステムにおいて、前記組織インターフェースの前記液体不透過性層が、ポリマーフィルムの第１のシートとポリマーフィルムの第２のシートとを含み、ポリマーフィルムの前記第１のシートとポリマーフィルムの前記第２のシートの各々の内面が、独立気泡を有する前記複数のバブルを備える密封領域を形成するように互いに封着されることを特徴とするシステム。 In the system of claim 1, the liquid impermeable layer of the tissue interface comprises a first sheet of polymer film and a second sheet of polymer film, said first sheet of polymer film and polymer. A system characterized in that the inner surfaces of each of the second sheets of film are sealed together to form a sealing region comprising the plurality of bubbles having closed cells. 請求項１１に記載のシステムにおいて、前記独立気泡が、ポリマーフィルムの前記第１のシートに形成されることを特徴とするシステム。 The system according to claim 11, wherein the closed cells are formed on the first sheet of the polymer film. 請求項１に記載のシステムにおいて、発泡体を含む発泡部材をさらに含むことを特徴とするシステム。 The system according to claim 1, further comprising a foaming member including a foam. 請求項１に記載のシステムにおいて、前記組織インターフェースと前記陰圧源とを流体的に結合するように適合された陰圧インターフェースをさらに備えることを特徴とするシステム。 The system according to claim 1, further comprising a negative pressure interface adapted to fluidly couple the tissue interface and the negative pressure source. 請求項１に記載のシステムにおいて、前記組織インターフェースが、こぶを備える複数の表面特徴部をさらに備えることを特徴とするシステム。 The system according to claim 1, wherein the tissue interface further comprises a plurality of surface features comprising humps. 請求項１５に記載のシステムにおいて、前記複数の表面特徴部が前記複数のバブル上に位置決めされることを特徴とするシステム。 The system according to claim 15, wherein the plurality of surface feature portions are positioned on the plurality of bubbles. 請求項１に記載のシステムにおいて、前記組織インターフェースが、前記液体不透過性層の中心部分に隣接して位置決めされるように適合された発泡体マニホールドをさらに備えることを特徴とするシステム。 The system according to claim 1, further comprising a foam manifold adapted such that the tissue interface is positioned adjacent to a central portion of the liquid impermeable layer. 請求項１に記載のシステムにおいて、前記複数のバブルが、
前記組織インターフェースの中心部分に位置決めされた第１の群のバブルであって、前記第１の群のバブルの各バブルが第１の直径を有する、前記第１の群のバブルと、
前記組織インターフェースの周縁部分に位置決めされた第２の群のバブルであって、前記第２の群のバブルの各バブルが第２の直径を有する、前記第２の群のバブルと
を備え、
前記第２の直径が前記第１の直径よりも大きい
ことを特徴とするシステム。 In the system according to claim 1, the plurality of bubbles are
A first group of bubbles positioned at the central portion of the tissue interface, wherein each bubble of the first group of bubbles has a first diameter, and the first group of bubbles.
A second group of bubbles positioned at the periphery of the tissue interface, comprising said second group of bubbles, wherein each bubble of the second group of bubbles has a second diameter.
A system characterized in that the second diameter is larger than the first diameter. 請求項１に記載のシステムにおいて、前記複数のバブルが、
前記組織インターフェースの中心部分に位置決めされた第１の群のバブルであって、前記第１の群のバブルが第１の間隔距離を有する、前記第１の群のバブルと、
前記組織インターフェースの周縁部分に位置決めされた第２の群のバブルであって、前記第２の群のバブルが第２の間隔距離を有する、前記第２の群のバブルと
を備え、
前記第２の間隔距離が前記第１の間隔距離より大きい
ことを特徴とするシステム。 In the system according to claim 1, the plurality of bubbles are
The first group of bubbles positioned at the central portion of the tissue interface, wherein the first group of bubbles has a first spacing distance, and the first group of bubbles.
A second group of bubbles positioned on a peripheral portion of the tissue interface, comprising said a second group of bubbles, wherein the second group of bubbles has a second spacing distance.
A system characterized in that the second spacing distance is larger than the first spacing distance. 請求項１に記載のシステムにおいて、前記複数のバブルの各々間の間隔距離が、前記組織インターフェースの中心部分から周縁に向かって前記組織インターフェースに沿って増加することを特徴とするシステム。 The system according to claim 1, wherein the spacing distance between each of the plurality of bubbles increases along the tissue interface from the central portion of the tissue interface toward the periphery. 請求項１に記載のシステムにおいて、前記複数のバブルの各々間の間隔距離が、前記組織インターフェースの中心部分から周縁に向かって前記組織インターフェースに沿って減少することを特徴とするシステム。 The system according to claim 1, wherein the spacing distance between each of the plurality of bubbles decreases along the tissue interface from the central portion of the tissue interface toward the periphery. 腹部組織部位を治療するためのドレッシングにおいて、
複数の窓を有する第１の液体不透過性層を含む有窓マニホールドであって、前記有窓マニホールドが第１の側面と第２の側面とを有する、前記有窓マニホールドと、
第２の液体不透過性層と、前記第２の液体不透過性層上に形成された複数のバブルとを備えるバブルマニホールドであって、前記バブルマニホールドが第１の側面と第２の側面とを有する、前記バブルマニホールドと、
前記バブルマニホールドの中心部分に隣接して位置決めされるように適合された発泡体マニホールドと
を備えることを特徴とするドレッシング。 In dressing to treat abdominal tissue sites
A windowed manifold comprising a first liquid permeable layer having a plurality of windows, wherein the windowed manifold has a first side surface and a second side surface.
A bubble manifold comprising a second liquid impermeable layer and a plurality of bubbles formed on the second liquid impermeable layer, wherein the bubble manifold has a first side surface and a second side surface. With the bubble manifold,
A dressing comprising a foam manifold adapted to be positioned adjacent to a central portion of the bubble manifold. 請求項２２に記載のドレッシングにおいて、前記バブルマニホールドは、前記バブルマニホールドの前記第１の側面が前記有窓マニホールドの前記第２の側面に接触するように、前記有窓マニホールドに隣接して位置決めされるように適合されることを特徴とするドレッシング。 In the dressing according to claim 22, the bubble manifold is positioned adjacent to the windowed manifold so that the first side surface of the bubble manifold is in contact with the second side surface of the windowed manifold. A dressing characterized by being adapted to. 請求項２２に記載のドレッシングにおいて、前記発泡体マニホールドが、発泡部材と、前記バブルマニホールドと共に前記発泡部材の周囲にシールを形成するように適合された液体不透過性材料の層とを備えることを特徴とするドレッシング。 22. In the dressing of claim 22, the foam manifold comprises a foam member and a layer of liquid impermeable material adapted to form a seal around the foam member together with the bubble manifold. Characteristic dressing. 請求項２２に記載のドレッシングにおいて、前記複数のバブルが連続気泡ブリスタを含むことを特徴とするドレッシング。 The dressing according to claim 22, wherein the plurality of bubbles include a continuous bubble blister. 請求項２５に記載のドレッシングにおいて、前記連続気泡ブリスタが、前記バブルマニホールドの前記第２の液体不透過性層に真空成形されることを特徴とするドレッシング。 The dressing according to claim 25, wherein the open cell blister is vacuum formed into the second liquid impermeable layer of the bubble manifold. 請求項２２に記載のドレッシングにおいて、前記複数のバブルが、流体を収容する独立気泡を含むことを特徴とするドレッシング。 22. The dressing according to claim 22, wherein the plurality of bubbles include closed bubbles containing a fluid. 請求項２２に記載のドレッシングにおいて、前記バブルマニホールドが、前記第２の液体不透過性層に形成された開口をさらに備え、前記開口が前記複数のバブル間に位置決めされることを特徴とするドレッシング。 22. The dressing according to claim 22, wherein the bubble manifold further comprises an opening formed in the second liquid impermeable layer, and the opening is positioned between the plurality of bubbles. .. 請求項２２に記載のドレッシングにおいて、前記複数のバブルが、前記バブルマニホールドの前記第１の側面から突出し、且つ前記有窓マニホールドの前記第２の側面に接触するように適合されることを特徴とするドレッシング。 22. The dressing of claim 22 is characterized in that the plurality of bubbles are adapted so as to protrude from the first side surface of the bubble manifold and come into contact with the second side surface of the windowed manifold. Dressing to do. 請求項２２に記載のドレッシングにおいて、前記複数のバブルの各々が、約１ｍｍ～５ｍｍの直径を有することを特徴とするドレッシング。 The dressing according to claim 22, wherein each of the plurality of bubbles has a diameter of about 1 mm to 5 mm. 請求項２２に記載のドレッシングにおいて、前記バブルマニホールドの前記第２の液体不透過性層が、ポリマーフィルムの第１のシートとポリマーフィルムの第２のシートとを含み、ポリマーフィルムの前記第１のシートとポリマーフィルムの前記第２のシートの各々の内面が、独立気泡を有する前記複数のバブルを備える密封領域を形成するように互いに封着されることを特徴とするドレッシング。 In the dressing according to claim 22, the second liquid impermeable layer of the bubble manifold comprises a first sheet of the polymer film and a second sheet of the polymer film, the first sheet of the polymer film. A dressing characterized in that the inner surface of each of the sheet and the second sheet of the polymer film is sealed to each other so as to form a sealing region having the plurality of bubbles having closed cells. 請求項２２に記載のドレッシングにおいて、前記バブルマニホールドが、中心部分と、前記中心部分から前記ドレッシングの周縁に向かって半径方向に離れるように延びる複数の流体チャネルとを備えることを特徴とするドレッシング。 22. The dressing according to claim 22, wherein the bubble manifold comprises a central portion and a plurality of fluid channels extending radially away from the central portion toward the periphery of the dressing. 請求項３２に記載のドレッシングにおいて、前記複数のバブルが前記複数の流体チャネルの各々に沿って位置決めされ、且つ前記複数のバブルが前記バブルマニホールドの前記第１の側面から突出することを特徴とするドレッシング。 The dressing according to claim 32 is characterized in that the plurality of bubbles are positioned along each of the plurality of fluid channels, and the plurality of bubbles project from the first side surface of the bubble manifold. dressing. 組織部位を治療するためのドレッシングにおいて、
第１の複数のバブルと第１の複数の開口とを備えるポリマーフィルムの第１のシートと、
第２の複数のバブルと第２の複数の開口とを備えるポリマーフィルムの第２のシートであって、ポリマーフィルムの前記第２のシートがポリマーフィルムの前記第１のシートと実質的に同延である、ポリマーフィルムの前記第２のシートと、
ポリマーフィルムの前記第１のシートの中心部分を貫通して形成され、且つポリマーフィルムの前記第１のシートとポリマーフィルムの前記第２のシートとの間の空間に治療流体を連通させるように適合された第１の流体経路と、
ポリマーフィルムの前記第１のシートとポリマーフィルムの前記第２のシートとを貫通して形成され、且つ前記組織部位に陰圧を連通させるように適合された第２の流体経路と
を備えることを特徴とするドレッシング。 In dressings for treating tissue sites
A first sheet of polymer film with a first plurality of bubbles and a first plurality of openings.
A second sheet of a polymer film comprising a second plurality of bubbles and a second plurality of openings, wherein the second sheet of the polymer film is substantially the same as the first sheet of the polymer film. With the second sheet of polymer film,
It is formed through the central portion of the first sheet of the polymer film and is adapted to allow the therapeutic fluid to communicate in the space between the first sheet of the polymer film and the second sheet of the polymer film. The first fluid path made and
It is provided with a second fluid path formed through the first sheet of the polymer film and the second sheet of the polymer film and adapted to communicate negative pressure to the tissue site. Characteristic dressing. 請求項３４に記載のドレッシングにおいて、前記第１の複数のバブル及び前記第２の複数のバブルが連続気泡ブリスタを含むことを特徴とするドレッシング。 The dressing according to claim 34 , wherein the first plurality of bubbles and the second plurality of bubbles include a continuous bubble blister. 組織部位を治療するためのシステムにおいて、
複数の窓を有する第１の液体不透過性層を含む有窓マニホールドであって、前記有窓マニホールドが第１の側面と第２の側面とを有する、前記有窓マニホールドと、
第２の液体不透過性層と、前記第２の液体不透過性層上に形成された複数のバブルとを備えるバブルマニホールドであって、前記バブルマニホールドが第１の側面と第２の側面とを有する、前記バブルマニホールドと、
流体分配ハブと、複数の流体分配チャネルとを備える流体分配マトリックスと
を備えることを特徴とするシステム。 In a system for treating tissue sites
A windowed manifold comprising a first liquid permeable layer having a plurality of windows, wherein the windowed manifold has a first side surface and a second side surface.
A bubble manifold comprising a second liquid impermeable layer and a plurality of bubbles formed on the second liquid impermeable layer, wherein the bubble manifold has a first side surface and a second side surface. With the bubble manifold,
A system comprising a fluid distribution hub and a fluid distribution matrix with a plurality of fluid distribution channels. 請求項３６に記載のシステムにおいて、前記バブルマニホールドが、前記バブルマニホールドの前記第１の側面が前記有窓マニホールドの前記第２の側面に接触するように、前記有窓マニホールドに隣接して位置決めされるように適合されることを特徴とするシステム。 In the system of claim 36 , the bubble manifold is positioned adjacent to the windowed manifold such that the first side surface of the bubble manifold contacts the second side surface of the windowed manifold. A system characterized by being adapted to. 請求項３６に記載のシステムにおいて、前記バブルマニホールドと流体連通するように適合された流体除去ハブをさらに備えることを特徴とするシステム。 36. The system of claim 36 , further comprising a fluid removal hub adapted to communicate with the bubble manifold. 請求項３６に記載のシステムにおいて、前記複数のバブルが連続気泡ブリスタを含むことを特徴とするシステム。 The system according to claim 36 , wherein the plurality of bubbles include a continuous bubble blister. 請求項３６に記載のシステムにおいて、前記複数のバブルが独立気泡を含むことを特徴とするシステム。 The system according to claim 36 , wherein the plurality of bubbles include closed bubbles. 請求項３６に記載のシステムにおいて、前記複数のバブルが、前記バブルマニホールドの前記第１の側面から突出し、且つ前記有窓マニホールドの前記第２の側面に接触するように適合されることを特徴とするシステム。 36. The system of claim 36 is characterized in that the plurality of bubbles are adapted to project from the first side surface of the bubble manifold and contact the second side surface of the windowed manifold. System to do. 請求項３６に記載のシステムにおいて、前記バブルマニホールドが、中心部分と、前記バブルマニホールドの前記中心部分から半径方向に延びる複数の流体チャネルとを備えることを特徴とするシステム。 36. The system of claim 36 , wherein the bubble manifold comprises a central portion and a plurality of fluid channels extending radially from the central portion of the bubble manifold. 請求項３６に記載のシステムにおいて、前記流体分配マトリックスに隣接して位置決めされるように適合され、且つ前記有窓マニホールドと第３の液体不透過性層との間に前記流体分配マトリックスを封入する前記第３の液体不透過性層をさらに備えることを特徴とするシステム。 In the system of claim 36 , the fluid distribution matrix is adapted to be positioned adjacent to the fluid distribution matrix and encapsulates the fluid distribution matrix between the windowed manifold and the third liquid impermeable layer. A system further comprising the third liquid impermeable layer. 請求項３６に記載のシステムにおいて、前記有窓マニホールド及び前記バブルマニホールドと流体連通するように適合された陰圧源をさらに備えることを特徴とするシステム。 36. The system of claim 36 , further comprising a windowed manifold and a negative pressure source adapted to communicate fluid with the bubble manifold. 請求項４４に記載のシステムにおいて、前記陰圧源を前記有窓マニホールドと前記バブルマニホールドとに流体的に結合するように適合されたインターフェースをさらに備えることを特徴とするシステム。 44. The system of claim 44 , further comprising an interface adapted to fluidly couple the negative pressure source to the windowed manifold and the bubble manifold. 請求項３６に記載のシステムにおいて、前記流体分配マトリックスに流体的に接続されるように適合された流体源をさらに備えることを特徴とするシステム。 36. The system of claim 36 , further comprising a fluid source adapted to be fluidly connected to the fluid distribution matrix.
JP2020546921A 2018-03-12 2019-01-11 Dressing with different surface features used in the compartment Pending JP2021517021A (en)

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US201862641841P 2018-03-12 2018-03-12
US62/641,841 2018-03-12
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