JPWO2018159708A1 - 血流解析装置および方法並びにプログラム - Google Patents
血流解析装置および方法並びにプログラム Download PDFInfo
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- 230000017531 blood circulation Effects 0.000 title claims abstract description 114
- 238000005206 flow analysis Methods 0.000 title claims abstract description 59
- 238000000034 method Methods 0.000 title claims abstract description 21
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 116
- 238000000605 extraction Methods 0.000 claims abstract description 13
- 239000000284 extract Substances 0.000 claims abstract description 10
- 238000003384 imaging method Methods 0.000 claims description 8
- 238000001646 magnetic resonance method Methods 0.000 claims description 5
- 238000002604 ultrasonography Methods 0.000 claims description 5
- 239000012530 fluid Substances 0.000 claims description 4
- 230000003247 decreasing effect Effects 0.000 claims description 3
- 230000006870 function Effects 0.000 claims description 2
- 238000002595 magnetic resonance imaging Methods 0.000 description 8
- 210000004351 coronary vessel Anatomy 0.000 description 7
- 238000010586 diagram Methods 0.000 description 7
- 230000010354 integration Effects 0.000 description 6
- 230000007423 decrease Effects 0.000 description 5
- 206010067171 Regurgitation Diseases 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 4
- 238000002591 computed tomography Methods 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000011218 segmentation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000013507 mapping Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000547 structure data Methods 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
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- A61B5/026—Measuring blood flow
- A61B5/0263—Measuring blood flow using NMR
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- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/06—Measuring blood flow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
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- A—HUMAN NECESSITIES
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- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
- A61B8/461—Displaying means of special interest
- A61B8/466—Displaying means of special interest adapted to display 3D data
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B8/48—Diagnostic techniques
- A61B8/483—Diagnostic techniques involving the acquisition of a 3D volume of data
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/48—Diagnostic techniques
- A61B8/488—Diagnostic techniques involving Doppler signals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
- A61B8/5223—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
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- G—PHYSICS
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- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/0285—Measuring or recording phase velocity of blood waves
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- A—HUMAN NECESSITIES
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- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
- A61B5/7425—Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image
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Abstract
Description
(Magnetic Resonance Imaging)装置および超音波撮影装置などによって撮影された3次元医用画像6を取得する。本実施形態では、患者の心臓(本発明の被写体に相当する)の3次元医用画像6(本発明の血管画像に相当する)を取得する場合について説明するが、これに限らず、肺、肝臓および頭部などその他の臓器でもよい。
2 医用画像保管サーバ
3 表示部
4 入力部
6 3次元医用画像
10 画像取得部
11 血管領域抽出部
12 流速ベクトル取得部
13 逆流特定部
14 表示制御部
B 血管領域
C 中心軸
R 逆流箇所
R1,R2 逆流箇所
S 断面
V 流速ベクトル
Vc 流速ベクトルの中心軸方向成分
Claims (16)
- 血管を含む被写体を撮影した血管画像から血管領域を抽出する血管領域抽出部と、
前記血管領域内における血流速度および血流方向を表す流速ベクトルを取得する流速ベクトル取得部と、
前記血管領域の延伸方向に延びる中心軸を設定し、前記流速ベクトルの前記中心軸の方向成分を時間軸方向に積分した積分値を算出し、前記積分値の変化に基づいて、前記血管領域内の血流の逆流の有無を特定する逆流特定部とを備えた血流解析装置。 - 前記逆流特定部が、前記積分値が単調増加または単調減少でない場合に、前記逆流が有ると特定する請求項1記載の血流解析装置。
- 前記逆流の箇所を前記血管領域の座標軸上にマッピングしたマップ画像を表示部に表示させる表示制御部を備えた請求項1または2記載の血流解析装置。
- 前記表示制御部が、前記流速ベクトルを予め設定された期間だけ積分した前記積分値を用いて前記マップ画像を生成する請求項3記載の血流解析装置。
- 前記予め設定された期間が、1心拍の期間である請求項4記載の血流解析装置。
- 前記表示制御部が、前記流速ベクトルを時間軸方向に積分する毎に前記マップ画像を時系列に生成して動画として前記表示部に表示させる請求項3記載の血流解析装置。
- 前記表示制御部が、前記マップ画像を2次元または3次元の血管画像に重畳表示させる請求項3から6いずれか1項記載の血流解析装置。
- 前記表示制御部が、前記積分値に基づいて、前記逆流の量の情報を前記表示部にさせる請求項3から7いずれか1項記載の血流解析装置。
- 前記表示制御部が、前記マップ画像以外の血流を示す指標を前記表示部に表示させる請求項3から8いずれか1項記載の血流解析装置。
- 前記血流を示す指標が、前記流速ベクトル、流線または流跡線である請求項9記載の血流解析装置。
- 前記逆流特定部が、前記血管領域のボクセル毎または複数のボクセル毎に前記積分値を算出する請求項1から10いずれか1項記載の血流解析装置。
- 前記逆流特定部が、前記血管領域の中心軸方向に直交する断面毎に前記積分値を算出する請求項1から10いずれか1項記載の血流解析装置。
- 前記流速ベクトル取得部が、時系列に撮影された3次元の血管画像または任意の時点において撮影された3次元の血管画像に基づいて、前記流速ベクトルを取得する請求項1から12いずれか1項記載の血流解析装置。
- 前記流速ベクトル取得部が、前記血管領域の数値流体力学(Computational Fluid Dynamics)モデル、3次元シネ位相コントラスト磁気共鳴法または3次元の超音波画像を用いて前記流速ベクトルを取得する請求項1から12いずれか1項記載の血流解析装置。
- 血管を含む被写体を撮影した血管画像から血管領域を抽出し、
前記血管領域内における血流速度および血流方向を表す流速ベクトルを取得し、
前記血管領域の延伸方向に延びる中心軸を設定し、前記流速ベクトルの前記中心軸の方向成分を時間軸方向に積分した積分値を算出し、前記積分値の変化に基づいて、前記血管領域内の血流の逆流の有無を特定する血流解析方法。 - コンピュータを、
血管を含む被写体を撮影した血管画像から血管領域を抽出する血管領域抽出部と、
前記血管領域内における血流速度および血流方向を表す流速ベクトルを取得する血流ベクトル取得部と、
前記血管領域の延伸方向に延びる中心軸を設定し、前記流速ベクトルの前記中心軸の方向成分を時間軸方向に積分した積分値を算出し、前記積分値の変化に基づいて、前記血管領域内の血流の逆流の有無を特定する逆流特定部として機能させる血流解析プログラム。
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PCT/JP2018/007610 WO2018159708A1 (ja) | 2017-02-28 | 2018-02-28 | 血流解析装置および方法並びにプログラム |
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JP2021186008A (ja) | 2020-05-26 | 2021-12-13 | キヤノンメディカルシステムズ株式会社 | 体液解析装置、体液解析装置の制御方法、およびプログラム |
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JP2004201730A (ja) * | 2002-12-24 | 2004-07-22 | Hitachi Ltd | 複数方向の投影映像を用いた3次元形状の生成方法 |
JP2005533593A (ja) * | 2002-07-25 | 2005-11-10 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 最適化された視野マップ |
JP2010075636A (ja) * | 2008-09-29 | 2010-04-08 | Toshiba Corp | 超音波診断装置及び超音波画像表示方法 |
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JP3517002B2 (ja) | 1994-11-30 | 2004-04-05 | 株式会社東芝 | 超音波診断装置 |
JP5196994B2 (ja) | 2007-12-27 | 2013-05-15 | 株式会社東芝 | 超音波診断装置、超音波画像処理装置及び超音波画像処理プログラム |
JP6162452B2 (ja) | 2013-03-28 | 2017-07-12 | 東芝メディカルシステムズ株式会社 | 血流解析装置及び血流解析プログラム |
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JP2005533593A (ja) * | 2002-07-25 | 2005-11-10 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 最適化された視野マップ |
JP2004201730A (ja) * | 2002-12-24 | 2004-07-22 | Hitachi Ltd | 複数方向の投影映像を用いた3次元形状の生成方法 |
JP2010075636A (ja) * | 2008-09-29 | 2010-04-08 | Toshiba Corp | 超音波診断装置及び超音波画像表示方法 |
US20180140420A1 (en) * | 2015-04-29 | 2018-05-24 | Kephalios S.A.S. | An annuloplasty system and a method for monitoring the effectiveness of an annuloplasty treatment |
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US20190374114A1 (en) | 2019-12-12 |
US11266322B2 (en) | 2022-03-08 |
JP6690053B2 (ja) | 2020-04-28 |
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