JPWO2014208446A1 - Syringe and flowable material transfer device - Google Patents

Syringe and flowable material transfer device Download PDF

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JPWO2014208446A1
JPWO2014208446A1 JP2015524010A JP2015524010A JPWO2014208446A1 JP WO2014208446 A1 JPWO2014208446 A1 JP WO2014208446A1 JP 2015524010 A JP2015524010 A JP 2015524010A JP 2015524010 A JP2015524010 A JP 2015524010A JP WO2014208446 A1 JPWO2014208446 A1 JP WO2014208446A1
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plunger
outer cylinder
syringe
wall surface
elastic piece
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JP6527463B2 (en
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利行 川島
利行 川島
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Otsuka Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/1782Devices aiding filling of syringes in situ
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513Piston constructions to improve sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2058Connecting means having multiple connecting ports
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048Connecting means
    • A61J1/2058Connecting means having multiple connecting ports
    • A61J1/2062Connecting means having multiple connecting ports with directional valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/20Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096Combination of a vial and a syringe for transferring or mixing their contents

Abstract

【課題】流動性物質を移送するためのシリンジおよび流動性物質移送具において、液密性と操作性との両方を向上させる。【解決手段】プランジャは、プランジャ本体と、このプランジャ本体の先端に一体に設けられ、外筒の内壁面に対して液密性を保持しながら摺動するプランジャ頭部とを有している。プランジャ頭部の先端周縁部には、プランジャが外筒内に挿着された状態で外筒の内壁面に弾性的に接触し、プランジャが押されたときに比べて、プランジャが引かれたときに、外筒の内壁面に対する抵抗値が減少する環状の弾性片が前方に向けて延設されている。これにより、プランジャを往復動させる際に、プランジャを押す力に比べて、プランジャを引く力が弱くなる場合であっても、シリンジの液密性と操作性との両方を向上させることができる。[PROBLEMS] To improve both liquid-tightness and operability in a syringe for transferring a fluid substance and a fluid substance transfer tool. The plunger has a plunger main body and a plunger head that is integrally provided at the tip of the plunger main body and slides while maintaining liquid tightness with respect to the inner wall surface of the outer cylinder. When the plunger is pulled compared to when the plunger is pressed against the inner peripheral wall of the outer cylinder in the state where the plunger is inserted into the outer cylinder at the peripheral edge of the plunger head. Further, an annular elastic piece whose resistance value with respect to the inner wall surface of the outer cylinder decreases is extended forward. Thereby, when reciprocating the plunger, both the liquid-tightness and the operability of the syringe can be improved even when the force of pulling the plunger is weaker than the force of pushing the plunger.

Description

本発明は、例えば、製剤、薬液等の流動性物質を収容容器から患者の投与部位(例えば瘻孔など)に移送して投与するのに好適なシリンジおよび流動性物質移送具に関するものである。   The present invention relates to a syringe and a flowable substance transfer device suitable for transferring and administering a flowable substance such as a preparation or a drug solution from a container to a patient administration site (for example, a fistula).

従来、この種のシリンジとしては、流動性物質を収容する外筒(シリンダ)と、この外筒内に往復動自在に挿着されるプランジャ(すなわち、ピストン)とから構成されたものが提案されている(例えば、特許文献1参照)。   Conventionally, as this type of syringe, a syringe composed of an outer cylinder (cylinder) that contains a fluid substance and a plunger (that is, a piston) that is removably inserted into the outer cylinder has been proposed. (For example, refer to Patent Document 1).

このシリンジでは、プランジャ頭部に可撓性の鍔部が横向き(すなわち、プランジャが往復動する方向に直角な方向)に形成されている。そして、所定の液密性を得るべく、この鍔部の外径を外筒の内径より少し大きくして鍔部を外筒に密着させるとともに、所定の操作性(すなわち、摺動の容易性)を得るべく、この鍔部を薄肉に形成している。   In this syringe, a flexible collar is formed on the plunger head in a lateral direction (that is, a direction perpendicular to the direction in which the plunger reciprocates). In order to obtain a predetermined liquid tightness, the outer diameter of the collar is slightly larger than the inner diameter of the outer cylinder so that the collar is brought into close contact with the outer cylinder, and predetermined operability (that is, ease of sliding). In order to obtain this, this buttock is formed thin.

特開2002−726号公報Japanese Patent Laid-Open No. 2002-726

このようなシリンジにおいては、プランジャ頭部の鍔部が横向きに設けられているため、プランジャを引くときとプランジャを押すときとで、外筒の内壁面と鍔部との接触面の摩擦係数は同程度になると考えられる。   In such a syringe, since the flange portion of the plunger head is provided sideways, the friction coefficient of the contact surface between the inner wall surface of the outer cylinder and the flange portion is different between when the plunger is pulled and when the plunger is pushed. It is considered to be the same level.

しかしながら、使用者は、プランジャを押す力に比べて、プランジャを引く力が弱くなる場合がある。このような場合、プランジャを引くときに要求される力が、押すときの要求される力よりも小さい方が、その使用者にとって操作性が良い。   However, the user may have a weaker pulling force than the pushing force of the plunger. In such a case, the operability for the user is better when the force required when pulling the plunger is smaller than the force required when pushing the plunger.

また、プランジャ頭部と外筒内壁面との接触部分の液密性を高めるため(すなわち、この接触部分から流動性物質が漏れ出すことを防止するため)には、これらプランジャ頭部と外筒内壁面との接圧を十分に高くすることが望ましい。しかしながら、この接圧を高くするほど、プランジャを押すときや引くときに使用者に必要な力が大きくなって、操作性が悪化する。   Further, in order to improve the liquid tightness of the contact portion between the plunger head and the inner cylinder inner wall surface (that is, to prevent the fluid substance from leaking out from the contact portion), the plunger head and the outer tube. It is desirable to make the contact pressure with the inner wall sufficiently high. However, the higher the contact pressure, the greater the force required for the user when pushing or pulling the plunger, and the operability deteriorates.

本発明は、このような事情に鑑み、プランジャを往復動させる際に、プランジャを押す力に比べて、プランジャを引く力が弱くて済み、且つ、液密性及びと操作性の両方に優れたシリンジを提供することを第1の目的とする。また、このようなシリンジを備えた流動性物質移送具を提供することを第2の目的とする。   In view of such circumstances, the present invention requires less force to pull the plunger than the force to push the plunger when reciprocating the plunger, and is excellent in both liquid tightness and operability. It is a first object to provide a syringe. A second object is to provide a flowable substance transfer device including such a syringe.

かかる目的を達成するため、本発明に係るシリンジは、流動性物質を収容する外筒内にプランジャが往復動自在に挿着され、前記プランジャを引くことにより、前記外筒の外部から内部へ前記流動性物質を吸引するとともに、前記プランジャを押すことにより、前記外筒の内部から外部へ前記流動性物質を押し出すシリンジであって、前記プランジャは、プランジャ本体と、このプランジャ本体の先端に一体に設けられ、前記外筒の内壁面に対して液密性を保持しながら摺動するプランジャ頭部とを有し、前記プランジャ頭部の先端周縁部には、前記プランジャが前記外筒内に挿着された状態で当該外筒の内壁面に弾性的に接触し、前記プランジャが押されたときに比べて、前記プランジャが引かれたときに、前記外筒の内壁面に対する抵抗値が減少する環状の弾性片が前方に向けて延設されていることを特徴とする。   In order to achieve this object, in the syringe according to the present invention, a plunger is reciprocally inserted in an outer cylinder containing a flowable substance, and the plunger is pulled to move the outer cylinder from the outside to the inside. A syringe that sucks a fluid substance and pushes the fluid substance from the inside of the outer cylinder to the outside by pushing the plunger, and the plunger is integrated with a plunger body and a tip of the plunger body. A plunger head that slides while maintaining liquid tightness with respect to the inner wall surface of the outer cylinder, and the plunger is inserted into the outer cylinder at a peripheral edge of the tip of the plunger head. When the plunger is pulled, the resistance against the inner wall surface of the outer cylinder is elastically contacted with the inner wall surface of the outer cylinder when worn and compared with when the plunger is pushed. There elastic piece of decreasing annular characterized in that it extends toward the front.

本発明のシリンジは、前記プランジャが引かれたときは、前記外筒内の圧力が低下して、前記弾性片と前記外筒の前記内壁面との接圧が減少することにより、前記抵抗値が減少し、前記プランジャが押されたときは、前記外筒内の圧力が上昇して、前記弾性片と前記外筒の前記内壁面との接圧が増大することにより、前記液密性が増大する、ように構成されることが望ましい。   In the syringe of the present invention, when the plunger is pulled, the pressure in the outer cylinder is reduced, and the contact pressure between the elastic piece and the inner wall surface of the outer cylinder is reduced. When the plunger is pushed, the pressure in the outer cylinder rises, and the contact pressure between the elastic piece and the inner wall surface of the outer cylinder increases, so that the liquid tightness is increased. It is desirable to be configured to increase.

本発明のシリンジにおいて、前記弾性片は、前記プランジャ頭部の先端周縁部に所定形状の溝が形成されることによって当該溝の外側に設けられることが望ましい。   In the syringe of the present invention, it is preferable that the elastic piece is provided outside the groove by forming a groove having a predetermined shape at the peripheral edge of the tip of the plunger head.

本発明のシリンジにおいて、前記溝は、略V形断面を有していることが望ましい。   In the syringe of the present invention, it is desirable that the groove has a substantially V-shaped cross section.

本発明のシリンジにおいて、前記弾性片は、前記プランジャが前記外筒内に挿着された状態で、当該外筒の前記内壁面に環状にほぼ線接触する当接部を有することが望ましい。   In the syringe of the present invention, it is desirable that the elastic piece has an abutting portion that substantially linearly contacts the inner wall surface of the outer cylinder in a state where the plunger is inserted into the outer cylinder.

本発明のシリンジにおいては、前記弾性片が、前記当接部と、前記当接部の後方に形成され、該当接部よりも小径で、且つ、外周面が前記プランジャの長手方向に沿って湾曲した湾曲面部と、前記当接部の前方に形成され、該当接部よりも小径で、且つ、外周面が前記プランジャの前記長手方向に沿って傾斜した傾斜面とを備えることが望ましい。   In the syringe of the present invention, the elastic piece is formed behind the contact portion and the contact portion, has a smaller diameter than the corresponding contact portion, and an outer peripheral surface is curved along the longitudinal direction of the plunger. It is desirable to include a curved surface portion and an inclined surface formed in front of the contact portion, having a smaller diameter than the corresponding contact portion, and having an outer peripheral surface inclined along the longitudinal direction of the plunger.

本発明のシリンジにおいては、前記流動性物質が製剤とすることができる。   In the syringe of the present invention, the fluid substance can be a preparation.

本発明の流動性物質移送具は、三方弁と、該三方弁の第1の分岐流路接続されたシリンジと、該三方弁の第2の分岐流路に取り付けられた、流動性物質を収容する容器に接続される容器連結部と、該三方弁第3の分岐流路接続された接続管とを備え、前記シリンジは、流動性物質を収容する外筒内にプランジャが往復動自在に挿着され、前記プランジャを引くことにより、前記外筒の外部から内部へ前記流動性物質を吸引するとともに、前記プランジャを押すことにより、前記外筒の内部から外部へ前記流動性物質を押し出すように構成され、前記プランジャは、プランジャ本体と、このプランジャ本体の先端に一体に設けられ、前記外筒の内壁面に対して液密性を保持しながら摺動するプランジャ頭部とを有し、前記プランジャ頭部の先端周縁部には、前記プランジャが前記外筒内に挿着された状態で当該外筒の内壁面に弾性的に接触し、前記プランジャが押されたときに比べて、前記プランジャが引かれたときに、前記外筒の内壁面に対する抵抗値が減少する環状の弾性片が前方に向けて延設されていることを特徴とする。   The flowable substance transfer device of the present invention contains a flowable substance attached to a three-way valve, a syringe connected to the first branch flow path of the three-way valve, and a second branch flow path of the three-way valve. And a connecting pipe connected to the third branch flow path of the three-way valve, and the syringe has a plunger reciprocally inserted in an outer cylinder containing a fluid substance. The fluid substance is sucked from the outside to the inside of the outer cylinder by pulling the plunger, and the fluid substance is pushed out from the inside of the outer cylinder by pushing the plunger. The plunger includes a plunger main body and a plunger head that is integrally provided at a tip of the plunger main body and slides while maintaining liquid tightness with respect to an inner wall surface of the outer cylinder, Plunger head tip When the plunger is pulled to the edge portion, the plunger is elastically contacted with the inner wall surface of the outer cylinder in a state where the plunger is inserted into the outer cylinder, and compared to when the plunger is pressed. Further, an annular elastic piece whose resistance value with respect to the inner wall surface of the outer cylinder decreases is extended forward.

本発明のシリンジによれば、プランジャ頭部の先端周縁部に弾性片が前方に向けて延設されており、プランジャが押されたときに比べて、プランジャが引かれたときに、外筒の内壁面に対する弾性片の抵抗値が減少する。その結果、プランジャを往復動させる際に、プランジャを押す力に比べて、プランジャを引く力が弱くなる場合であっても、液密性と操作性を両立させることが可能なシリンジを提供することができる。   According to the syringe of the present invention, the elastic piece extends forward at the distal end peripheral portion of the plunger head, and when the plunger is pulled compared to when the plunger is pushed, The resistance value of the elastic piece with respect to the inner wall surface decreases. As a result, it is possible to provide a syringe capable of achieving both liquid-tightness and operability even when the plunger pulling force is weaker than the plunger pushing force when the plunger is reciprocated. Can do.

本発明のシリンジを、プランジャが引かれたときは外筒の内壁面との接圧が減少し、且つ、プランジャが押されたときはその接圧が増大するように構成することで、操作性と密着性との両方を向上させることができる。   The syringe of the present invention is configured such that when the plunger is pulled, the contact pressure with the inner wall surface of the outer cylinder decreases, and when the plunger is pressed, the contact pressure increases. Both adhesion and adhesion can be improved.

本発明のシリンジにおいて、プランジャ頭部の先端周縁部に所定形状の溝を形成することにより、弾性片を簡単に形成することができる。   In the syringe of the present invention, the elastic piece can be easily formed by forming a groove having a predetermined shape in the peripheral edge of the tip of the plunger head.

本発明のシリンジにおいて、上記溝の断面を略V形とすることにより、上記のような接圧の減少や増大を十分に大きくすることが容易になる。   In the syringe of the present invention, by making the cross section of the groove substantially V-shaped, it becomes easy to sufficiently increase the decrease or increase in contact pressure as described above.

本発明のシリンジにおいて、プランジャ頭部の弾性片と外筒の内壁面とをほぼ線接触とすることにより、面接触する場合に比べて、両者の接触面積が減少するため、外筒の内壁面に対する弾性片の抵抗値を抑えることができるばかりか、両者の単位面積当たりの接圧を高めることにより、シリンジの液密性を向上させることが可能となる。   In the syringe according to the present invention, since the elastic piece of the plunger head and the inner wall surface of the outer cylinder are substantially in line contact with each other, the contact area between the two is reduced compared to the case of surface contact. Not only can the resistance value of the elastic piece to be suppressed, but also by increasing the contact pressure per unit area of both, the liquid tightness of the syringe can be improved.

本発明のシリンジにおいて、弾性片に湾曲面部と傾斜面部とを設けることにより、当接部の摩擦抵抗を十分に減らすことができる。   In the syringe of the present invention, by providing the elastic piece with the curved surface portion and the inclined surface portion, the frictional resistance of the contact portion can be sufficiently reduced.

本発明のシリンジにおいて、流動性物質を製剤とすることにより、上述した効果を奏する製剤投与用のシリンジを得ることができる。   In the syringe of the present invention, by using a fluid substance as a preparation, a preparation administration syringe having the above-described effects can be obtained.

本発明の流動性物質移送具によれば、上述した効果を奏するシリンジを備えた流動性物質移送具を提供することができる。   According to the flowable substance transfer device of the present invention, it is possible to provide a flowable material transfer device provided with a syringe having the above-described effects.

本発明の実施の形態1に係る流動性物質移送具を示す正面図である。It is a front view which shows the fluid substance transfer tool which concerns on Embodiment 1 of this invention. 同実施の形態1に係る流動性物質移送具のシリンジのプランジャを示す図であって、(a)はその正面図、(b)はその左側面図である。It is a figure which shows the plunger of the syringe of the fluid substance transfer tool which concerns on the same Embodiment 1, Comprising: (a) is the front view, (b) is the left view. 同実施の形態1に係るプランジャの断面形状の一例を示す拡大詳細図である。FIG. 3 is an enlarged detail view showing an example of a cross-sectional shape of the plunger according to the first embodiment. 同実施の形態1に係るプランジャの断面形状の一例を示す拡大詳細図である。FIG. 3 is an enlarged detail view showing an example of a cross-sectional shape of the plunger according to the first embodiment. 同実施の形態1に係るプランジャの断面形状の一例を示す拡大詳細図である。FIG. 3 is an enlarged detail view showing an example of a cross-sectional shape of the plunger according to the first embodiment. 同実施の形態1に係るプランジャの断面形状の一例を示す拡大詳細図である。FIG. 3 is an enlarged detail view showing an example of a cross-sectional shape of the plunger according to the first embodiment. 同実施の形態1に係るプランジャの溝の深さと、プランジャを引くときの抵抗値との関係を示す棒グラフである。It is a bar graph which shows the relationship between the depth of the groove | channel of the plunger which concerns on the same Embodiment 1, and resistance value when pulling a plunger. 同実施の形態1に係るプランジャの溝の深さと、プランジャを押すときの抵抗値との関係を示す棒グラフである。It is a bar graph which shows the relationship between the depth of the groove | channel of the plunger which concerns on the same Embodiment 1, and resistance value when pushing a plunger.

以下、本発明の実施の形態について説明する。
[発明の実施の形態1]
図1乃至図4Bは、本発明の実施の形態1を示す。なお、図3A〜図4Dはいずれも、図2に示すプランジャ頭部のC−C線による拡大断面図である。
Embodiments of the present invention will be described below.
Embodiment 1 of the Invention
1 to 4B show Embodiment 1 of the present invention. 3A to 4D are all enlarged cross-sectional views taken along the line CC of the plunger head shown in FIG.

実施の形態1に係る流動性物質移送具1は、図1に示すように、製剤が収容された収容容器2に連結して、この製剤を収容容器2から患者の投与部位に移送して投与するために使用される。この流動性物質移送具1は、第1〜第3の分岐流路41、42、43が合流部44でT字形に合流する構造を有する透明な合成樹脂製の三方弁4と、この三方弁4の第1の分岐流路41に連通して接続されたシリンジ3と、三方弁4の第2の分岐流路42に取り付けられた容器連結部5と、三方弁4の第3の分岐流路43に連通して接続された接続管6とを備えている。   As shown in FIG. 1, a fluid substance transfer device 1 according to Embodiment 1 is connected to a container 2 in which a preparation is stored, and this preparation is transferred from the container 2 to a patient's administration site for administration. Used to do. This fluid substance transfer device 1 includes a three-way valve 4 made of a transparent synthetic resin having a structure in which the first to third branch passages 41, 42, and 43 join together in a T-shape at the joining portion 44, and the three-way valve. 4, the syringe 3 connected in communication with the first branch flow path 41, the container connecting portion 5 attached to the second branch flow path 42 of the three-way valve 4, and the third branch flow of the three-way valve 4. And a connection pipe 6 connected in communication with the path 43.

ここで、三方弁4の第2の分岐流路42には、図1に示すように、第1の逆止弁10が、収容容器2から合流部44への流れ(図1上方への流れ)を許容するとともに、逆向きの流れ(図1下方への流れ)を阻止するように取り付けられている。また、三方弁4の第3の分岐流路43には、第2の逆止弁11が、合流部44から接続管6への流れ(図1左方への流れ)を許容するとともに、逆向きの流れ(図1右方への流れ)を阻止するように取り付けられている。   Here, in the second branch flow path 42 of the three-way valve 4, as shown in FIG. 1, the first check valve 10 flows from the container 2 to the junction 44 (flow upward in FIG. 1). ) And the reverse flow (downward flow in FIG. 1) is prevented. Further, in the third branch flow path 43 of the three-way valve 4, the second check valve 11 allows a flow from the joining portion 44 to the connecting pipe 6 (flow to the left in FIG. 1) and reversely. It is attached so as to prevent the flow in the direction (flow to the right in FIG. 1).

また、シリンジ3は、図1に示すように、製剤を収容する略円筒状の透明な合成樹脂製の外筒31を有しており、この外筒31は三方弁4の第1の分岐流路41に一体に形成されている。外筒31内には、ポリエチレン製のプランジャ32が、外筒31の管心方向(矢印A、B方向)に往復動自在に挿着されている。そして、プランジャ32を引くことにより、外筒31の外部(三方弁4側)から外筒31の内部へ製剤を吸引するとともに、プランジャ32を押すことにより、外筒31の内部から外筒31の外部(三方弁4側)へ製剤を押し出すことができるように構成されている。   Further, as shown in FIG. 1, the syringe 3 has a substantially cylindrical transparent synthetic resin outer cylinder 31 that accommodates the preparation. The outer cylinder 31 is a first branch flow of the three-way valve 4. It is formed integrally with the path 41. A polyethylene plunger 32 is inserted into the outer cylinder 31 so as to be capable of reciprocating in the tube center direction of the outer cylinder 31 (directions of arrows A and B). Then, by pulling the plunger 32, the preparation is sucked from the outside of the outer cylinder 31 (the three-way valve 4 side) into the outer cylinder 31, and by pushing the plunger 32, the outer cylinder 31 is moved from the inside of the outer cylinder 31. It is comprised so that a formulation can be extruded to the exterior (three-way valve 4 side).

このプランジャ32は、図2に示すように、プランジャ本体33とプランジャ頭部34とを有している。プランジャ本体33は、断面が略十字形の、柱状に形成されている。また、プランジャ頭部34は、略円盤状に形成され、プランジャ本体33の先端に一体に設けられて、外筒31の内壁面31aに対して液密性を保持しながら摺動する。   As shown in FIG. 2, the plunger 32 has a plunger main body 33 and a plunger head 34. The plunger body 33 is formed in a columnar shape having a substantially cross-shaped cross section. The plunger head 34 is formed in a substantially disk shape, is provided integrally with the tip of the plunger body 33, and slides while maintaining liquid tightness with respect to the inner wall surface 31 a of the outer cylinder 31.

ここで、プランジャ頭部34の先端周縁部34aには、図2(b)および図3A−Dに示すように、分岐流路41と対向させて、円環状で断面がV字形の溝36が形成されている。これにより、この溝36の外周側には、円環状の弾性片35が形成されている。なお、後述するように、図3A−図3Dに示したプランジャ頭部34は、深さD(図3A参照)が互いに異なる。   Here, in the distal end peripheral portion 34a of the plunger head portion 34, as shown in FIG. 2B and FIGS. 3A to 3D, an annular groove V having a V-shaped cross section is provided so as to face the branch flow path 41. Is formed. Thereby, an annular elastic piece 35 is formed on the outer peripheral side of the groove 36. As will be described later, the plunger head 34 shown in FIGS. 3A to 3D has different depths D (see FIG. 3A).

図3A−図3Dに示したように、弾性片35は、当接部35a、湾曲面部35b及び傾斜面部35cを含む。当接部35aは、外筒31の内壁面31aに円環状にほぼ線接触する。湾曲面部35bは、当接部35aの後方(すなわち、プランジャ本体33側)に設けられており、当接部35aよりも小径で、且つ、外周面がプランジャ32の長手方向(A、Bで示した移動方向)に沿って湾曲している。また、傾斜面部35cは、当接部31aの前方(すなわち、分岐流路41側)に設けられており、当接部35aよりも小径で、且つ、外周面がプランジャ32の長手方向に沿って傾斜している。このような構成により、当接部35aの摩擦係数を、十分に低く抑えることが可能となる(後述)。なお、プランジャ32が外筒31内に挿着されていない状態では、図3に想像線で示すように、プランジャ32が外筒31内に挿着された状態に比べて、弾性片35が少し外側に開いた状態になっている。   As shown in FIGS. 3A to 3D, the elastic piece 35 includes a contact portion 35a, a curved surface portion 35b, and an inclined surface portion 35c. The abutting portion 35a is in substantially line contact with the inner wall surface 31a of the outer cylinder 31 in an annular shape. The curved surface portion 35b is provided behind the contact portion 35a (that is, on the plunger main body 33 side), has a smaller diameter than the contact portion 35a, and has an outer peripheral surface indicated by the longitudinal direction of the plunger 32 (A and B). Curved in the direction of travel). The inclined surface portion 35 c is provided in front of the contact portion 31 a (that is, on the branch flow path 41 side), has a smaller diameter than the contact portion 35 a, and an outer peripheral surface along the longitudinal direction of the plunger 32. Inclined. With such a configuration, the friction coefficient of the contact portion 35a can be kept sufficiently low (described later). In the state where the plunger 32 is not inserted into the outer cylinder 31, the elastic piece 35 is slightly smaller than the state where the plunger 32 is inserted into the outer cylinder 31, as indicated by the imaginary line in FIG. It is in the open state on the outside.

この弾性片35のサイズとしては、その強度や液密性を確保する観点から、弾性片35の幅をプランジャ頭部34の直径の4.7〜5.6%とし、弾性片35の高さをプランジャ頭部34の厚さの39.6〜63.0%とするのが好ましい。   As the size of the elastic piece 35, the width of the elastic piece 35 is set to 4.7 to 5.6% of the diameter of the plunger head 34 from the viewpoint of ensuring the strength and liquid tightness, and the height of the elastic piece 35 is set. Is preferably 39.6 to 63.0% of the thickness of the plunger head 34.

流動性物質移送具1は以上のような構成を有するので、次の手順により、この流動性物質移送具1を用いて、製剤を収容容器2から患者の投与部位に移送して投与することができる。   Since the fluid substance transfer device 1 has the above-described configuration, it is possible to transfer and administer the preparation from the container 2 to the administration site of the patient using the fluid substance transfer device 1 according to the following procedure. it can.

まず、準備工程で、製剤が収容された収容容器2に流動性物質移送具1の容器連結部5を連結する。また、この流動性物質移送具1の接続管6を患者の投与部位に接続する。   First, in the preparation step, the container connecting portion 5 of the fluid substance transfer device 1 is connected to the storage container 2 in which the preparation is stored. Further, the connecting pipe 6 of the fluid substance transfer device 1 is connected to the administration site of the patient.

次に、移送実行工程に移行する。この移送実行工程では、まず、利用者が、シリンジ3のプランジャ32を引く(すなわち、プランジャ32を、図3AのB方向に移動させる)。これにより、収容容器2内及び三方弁4内が負圧(すなわち、大気圧より低い気圧)になって、収容容器2内の製剤が、第1の逆止弁10および三方弁4を経由して、シリンジ3内(すなわち、外筒31内)に吸い込まれる。   Next, the process proceeds to the transfer execution process. In this transfer execution step, first, the user pulls the plunger 32 of the syringe 3 (that is, moves the plunger 32 in the direction B of FIG. 3A). Thereby, the inside of the storage container 2 and the inside of the three-way valve 4 become negative pressure (that is, the pressure lower than the atmospheric pressure), and the preparation in the storage container 2 passes through the first check valve 10 and the three-way valve 4. Then, it is sucked into the syringe 3 (that is, inside the outer cylinder 31).

ここで、プランジャ頭部34には略V形断面で円環状の溝36が設けられているので、収容容器2内が負圧になったとき、弾性片35は内側方向(すなわち、溝36の幅が狭まる方向)の力を受ける。このため、この弾性片35の当接部35aと外筒31の内壁面31aとが接触した部分の接圧が小さくなって、この接触部分の摩擦係数が低下する。   Here, since the plunger head 34 is provided with an annular groove 36 having a substantially V-shaped cross section, when the inside of the container 2 becomes negative pressure, the elastic piece 35 moves in the inner direction (that is, in the groove 36. Receives force in the direction of narrowing). For this reason, the contact pressure of the portion where the contact portion 35a of the elastic piece 35 and the inner wall surface 31a of the outer cylinder 31 are in contact with each other is reduced, and the friction coefficient of the contact portion is reduced.

この結果、利用者がプランジャ32を引く際に必要な力は、小さくなる。なお、当接部35aと内壁面31aとの接圧が低下することにより、この当接部分での液密性は低下する。しかし、このとき、収容容器2内及び三方弁4内は負圧になっているので、この当接部分から製剤が漏れ出すおそれは無い。   As a result, the force required when the user pulls the plunger 32 is reduced. In addition, when the contact pressure between the contact portion 35a and the inner wall surface 31a decreases, the liquid tightness at the contact portion decreases. However, at this time, the inside of the container 2 and the inside of the three-way valve 4 are in a negative pressure, so there is no possibility that the preparation leaks from this contact portion.

所望の量の製剤が三方弁4内及びシリンジ3内に収容されると、続いて、利用者が、シリンジ3のプランジャ32を押す(すなわち、プランジャ32を、図3AのA方向に移動させる)。これにより、三方弁4内及びシリンジ3内が正圧(すなわち、大気圧よりも高い気圧)になって、シリンジ3内に収容された製剤が、この外筒31から押し出され、三方弁4、第2の逆止弁11および接続管6を経由して、患者の投与部位に移送される。   When a desired amount of the preparation is contained in the three-way valve 4 and the syringe 3, the user subsequently pushes the plunger 32 of the syringe 3 (ie, moves the plunger 32 in the direction A of FIG. 3A). . Thereby, the inside of the three-way valve 4 and the inside of the syringe 3 become a positive pressure (that is, an atmospheric pressure higher than the atmospheric pressure), and the preparation contained in the syringe 3 is pushed out from the outer cylinder 31, and the three-way valve 4, It is transferred to the administration site of the patient via the second check valve 11 and the connecting pipe 6.

このとき、収容容器2内の製剤が溝36内に入り込んで、弾性片35は外側方向(すなわち、溝36の幅が拡がる方向)の力を受ける。このため、この弾性片35の当接部35aと外筒31の内壁面31aとが接触した部分の接圧が大きくなって、この接触部分の摩擦係数が増大する。この結果、利用者がプランジャ32を押す際に必要な力は、このプランジャ32を引くときよりも大きくなる。また、当接部35aと内壁面31aとの接圧が増大することにより、この当接部分での液密性が向上するので、この当接部分から製剤が漏れ出し難くなる。   At this time, the preparation in the container 2 enters the groove 36, and the elastic piece 35 receives a force in the outer direction (that is, the direction in which the width of the groove 36 increases). For this reason, the contact pressure of the portion where the contact portion 35a of the elastic piece 35 and the inner wall surface 31a of the outer cylinder 31 are in contact increases, and the friction coefficient of the contact portion increases. As a result, the force required when the user pushes the plunger 32 becomes larger than when the plunger 32 is pulled. Further, since the contact pressure between the contact portion 35a and the inner wall surface 31a is increased, the liquid tightness at the contact portion is improved, so that it is difficult for the preparation to leak from the contact portion.

また、シリンジ3は、上述したとおり、外筒31内にプランジャ32が挿着された状態で、外筒31の内壁面31aに弾性片35の当接部35aが円環状にほぼ線接触している。したがって、外筒31の内壁面31aに弾性片35の当接部35aが面接触する場合に比べて、両者(外筒31の内壁面31aおよび弾性片35の当接部35a)の接触面積が減少するため、外筒31の内壁面31aに対する弾性片35の抵抗値を抑えることができる。加えて、両者の単位面積当たりの接圧を高めることにより、シリンジ3の液密性を向上させることが可能となる。しかも、当接部35Aの位置が弾性片35の先端部側であるため、この位置が弾性片35の後端部側である場合に比べて、プランジャ32が分岐流路41に最近接する位置まで移動したときに外筒31内に残る製剤の残留量を減らすことができる。   Further, as described above, in the syringe 3, with the plunger 32 inserted in the outer cylinder 31, the abutting portion 35 a of the elastic piece 35 is substantially in line contact with the inner wall surface 31 a of the outer cylinder 31. Yes. Therefore, compared with the case where the contact portion 35a of the elastic piece 35 is in surface contact with the inner wall surface 31a of the outer cylinder 31, the contact area between the two (the inner wall surface 31a of the outer cylinder 31 and the contact portion 35a of the elastic piece 35) is larger. Since it decreases, the resistance value of the elastic piece 35 with respect to the inner wall surface 31a of the outer cylinder 31 can be suppressed. In addition, the liquid tightness of the syringe 3 can be improved by increasing the contact pressure per unit area of both. In addition, since the position of the abutting portion 35A is on the distal end side of the elastic piece 35, the position where the plunger 32 is closest to the branch flow path 41 as compared with the case where this position is on the rear end side of the elastic piece 35. The residual amount of the preparation remaining in the outer cylinder 31 when moved can be reduced.

さらに、弾性片35は、上述したとおり、プランジャ頭部34の先端周縁部34aに溝36が形成されることによって設けられているため、プランジャ32が分岐流路41に最接近する位置まで移動したときに、弾性片35が外筒31の底部に当たっても損傷を受け難く、また、外筒31内に残る製剤の残留量を少量(溝36の容積にほぼ等しい量)にとどめることができる。しかも、この溝36が略V形断面であるため、プランジャ32が押されて、弾性片35は外側に開く向きに外力を受けたときに、外筒31の内壁面31aに対する弾性片35の抵抗値が増大するという作用を働かせ易くなる。   Further, as described above, since the elastic piece 35 is provided by forming the groove 36 in the distal end peripheral portion 34a of the plunger head 34, the plunger 32 has moved to the position where the plunger 32 is closest to the branch flow path 41. Sometimes, even if the elastic piece 35 hits the bottom of the outer cylinder 31, it is not easily damaged, and the residual amount of the preparation remaining in the outer cylinder 31 can be kept small (an amount approximately equal to the volume of the groove 36). Moreover, since the groove 36 has a substantially V-shaped cross section, the resistance of the elastic piece 35 to the inner wall surface 31a of the outer cylinder 31 when the plunger 32 is pushed and the elastic piece 35 receives an external force in the direction of opening outward. It becomes easy to work the effect that the value increases.

なお、三方弁4には、上述したとおり、第2および第3の分岐流路42、43にそれぞれ第1および第2の逆止弁10、11が適宜取り付けられているので、この移送実行工程において、収容容器2からシリンジ3の外筒31内に移送された製剤が収容容器2に逆流するような事態は生じず、製剤の移送を円滑に行うことができる。   As described above, since the first and second check valves 10 and 11 are appropriately attached to the second and third branch flow paths 42 and 43 in the three-way valve 4, this transfer execution step. Therefore, the situation where the preparation transferred from the container 2 into the outer cylinder 31 of the syringe 3 flows back to the container 2 does not occur, and the preparation can be transferred smoothly.

上述した効果を確認するため、直径15.3mm、厚さ2.3mmの略円板状のプランジャ頭部34の先端周縁部34aに、図3A−図3Dに示すように、略V形断面円環状の溝36を4種類の深さD(D=1.51mm、1.25mm、0.92mm、0.61mm)で形成して、4種類のポリエチレン製のプランジャ32を試作した。   In order to confirm the above-described effect, a substantially V-shaped cross-sectional circle is formed on the distal end peripheral portion 34a of the substantially disc-shaped plunger head 34 having a diameter of 15.3 mm and a thickness of 2.3 mm, as shown in FIGS. 3A to 3D. The annular groove 36 was formed with four types of depths D (D = 1.51 mm, 1.25 mm, 0.92 mm, 0.61 mm), and four types of polyethylene plungers 32 were made as prototypes.

そして、これら4種類の試作品1〜4について、それぞれ、製剤なしの場合(収容容器2に空気を収容した場合)および製剤ありの場合(収容容器2の所定の製剤を収容した場合)とで、プランジャ32を引いたとき、外筒31の内壁面31aに対する弾性片35の抵抗値がどのように変化するかを調べた。その結果を図4Aに棒グラフで示す。この棒グラフにおいて、縦軸は抵抗値(単位:ニュートン)を表している。図4Aから明らかなように、プランジャ32を引いたときの抵抗値と溝36の深さDとの関係については、製剤なしの場合と製剤ありの場合の別を問わず、溝36が浅くなるほど、プランジャ32を引いたときの抵抗値が増大する傾向にあることが認められた。   And about these four types of prototypes 1-4, when there is no formulation (when air is contained in the container 2) and when there is a formulation (when a predetermined formulation in the container 2 is accommodated), respectively. When the plunger 32 was pulled, it was examined how the resistance value of the elastic piece 35 against the inner wall surface 31a of the outer cylinder 31 changes. The results are shown as a bar graph in FIG. 4A. In this bar graph, the vertical axis represents the resistance value (unit: Newton). As is clear from FIG. 4A, regarding the relationship between the resistance value when the plunger 32 is pulled and the depth D of the groove 36, the shallower the groove 36, regardless of whether the preparation is not present or not. It was recognized that the resistance value when the plunger 32 was pulled tends to increase.

また、これら4種類の試作品1〜4について、それぞれ、製剤なしの場合(収容容器2に空気を収容した場合)および製剤ありの場合(収容容器2の所定の製剤を収容した場合)に、プランジャ32を押したとき、外筒31の内壁面31aに対する弾性片35の抵抗値がどのように変化するかを調べた。その結果を図4Bに棒グラフで示す。この棒グラフにおいて、縦軸は抵抗値(単位:ニュートン)を表している。図4Bから明らかなように、プランジャ32を押したときの抵抗値と溝36の深さDとの関係については、製剤なしの場合と製剤ありの場合の別を問わず、溝36が浅くなるほど、プランジャ32を押したときの抵抗値が増大する傾向にあることが認められた。   In addition, for these four types of prototypes 1 to 4, respectively, when there is no formulation (when air is contained in the container 2) and when there is a formulation (when the predetermined formulation in the container 2 is accommodated), It was examined how the resistance value of the elastic piece 35 with respect to the inner wall surface 31a of the outer cylinder 31 changes when the plunger 32 is pushed. The results are shown as a bar graph in FIG. 4B. In this bar graph, the vertical axis represents the resistance value (unit: Newton). As is clear from FIG. 4B, regarding the relationship between the resistance value when the plunger 32 is pushed and the depth D of the groove 36, the shallower the groove 36, regardless of whether the preparation is not present or not. It was recognized that the resistance value when the plunger 32 was pushed tends to increase.

そして、図4A、図4Bを対比すれば明らかなように、試作品1〜4のいずれについても、特に製剤ありの場合に、プランジャ32を押したときの抵抗値よりプランジャ32を引いたときの抵抗値が小さくなった。すなわち、プランジャ32を往復動させる際に、利用者がプランジャ32を押す力に比べて、プランジャ32を引く力が弱くなる場合であっても、シリンジ3の液密性と操作性を両立させることができることを裏付ける結果が得られた。   4A and 4B, it is clear that when the plunger 32 is subtracted from the resistance value when the plunger 32 is pushed, particularly in the case of the preparations, in any of the prototypes 1 to 4 The resistance value has decreased. That is, when the plunger 32 is reciprocated, the liquid tightness and the operability of the syringe 3 can be made compatible even when the force of pulling the plunger 32 is weaker than the force by which the user pushes the plunger 32. The result which proves that can be done was obtained.

[発明のその他の実施の形態]
なお、上述した実施の形態1では、三方弁4とシリンジ3の外筒31とが一体に形成された流動性物質移送具1について説明した。しかし、三方弁4とシリンジ3の外筒31とが別個に設けられた流動性物質移送具1に本発明を同様に適用することもできる。さらに、三方弁4を備えていない流動性物質移送具1に本発明を同様に適用することも可能である。
[Other Embodiments of the Invention]
In the first embodiment described above, the fluid substance transfer device 1 in which the three-way valve 4 and the outer cylinder 31 of the syringe 3 are integrally formed has been described. However, the present invention can be similarly applied to the fluid substance transfer device 1 in which the three-way valve 4 and the outer cylinder 31 of the syringe 3 are separately provided. Furthermore, it is also possible to apply the present invention to the flowable material transfer device 1 that does not include the three-way valve 4.

また、上述した実施の形態1では、プランジャ頭部34の先端周縁部34aに略V形断面円環状の溝36が形成されたプランジャ32について説明した。しかし、この溝36の形状は、必ずしも略V形断面円環状である必要はなく、プランジャ頭部34の先端周縁部34aに所定の弾性片35が設けられる限り、略V形断面円環状の溝36以外の溝(例えば、略U形断面の溝、略レ形断面の溝、略I形断面の溝など)を形成するようにしてもよい。   Further, in the first embodiment described above, the plunger 32 in which the groove 36 having a substantially V-shaped annular ring is formed in the distal end peripheral portion 34a of the plunger head 34 has been described. However, the shape of the groove 36 is not necessarily an annular shape having a substantially V-shaped cross section. As long as a predetermined elastic piece 35 is provided on the distal end peripheral portion 34a of the plunger head 34, the groove having a substantially V-shaped annular shape is provided. Grooves other than 36 (for example, a groove having a substantially U-shaped cross section, a groove having a substantially L-shaped cross section, a groove having a substantially I-shaped cross section, etc.) may be formed.

また、上述した実施の形態1では、ポリエチレン製のプランジャ32について説明した。しかし、プランジャ32の材質は、ポリエチレンに限るわけではなく、ポリプロピレン、ポリカーボネート、ポリアミド、ポリエチレンテレフタレートなど他の合成樹脂を採用することもできる。さらに、合成樹脂以外の材質(例えば、金属、ガラスなど)を代用しても構わない。   Moreover, in Embodiment 1 mentioned above, the plunger 32 made from polyethylene was demonstrated. However, the material of the plunger 32 is not limited to polyethylene, and other synthetic resins such as polypropylene, polycarbonate, polyamide, and polyethylene terephthalate can be used. Furthermore, materials other than synthetic resin (for example, metal, glass, etc.) may be substituted.

また、上述した実施の形態1において、外筒31の内壁面31aに対する弾性片35の摩擦抵抗値を減少させるため、潤滑油、グリースなどの潤滑剤を外筒31の内壁面31aに塗布してもよいことは言及するまでもない。   In the first embodiment described above, a lubricant such as lubricating oil or grease is applied to the inner wall surface 31 a of the outer cylinder 31 in order to reduce the frictional resistance value of the elastic piece 35 against the inner wall surface 31 a of the outer cylinder 31. Needless to say.

また、上述した実施の形態1では、流動性物質移送具1に用いられるシリンジ3について説明した。しかし、流動性物質移送具1以外の器具・装置(例えば、注射器、分注器、分析機器など)に用いられるシリンジ3に本発明を同様に適用することもできる。   Moreover, in Embodiment 1 mentioned above, the syringe 3 used for the fluid substance transfer tool 1 was demonstrated. However, the present invention can be similarly applied to a syringe 3 used in an instrument / device other than the fluid substance transfer tool 1 (for example, a syringe, a dispenser, an analytical instrument, etc.).

さらに、上述した実施の形態1では、流動性物質移送具1で取り扱う流動性物質が製剤である場合について説明したが、製剤以外の流動性物質(例えば、栄養組成物、血液、接着剤など)を取り扱う場合に本発明を同様に適用することも可能である。   Furthermore, although Embodiment 1 mentioned above demonstrated the case where the fluid substance handled with the fluid substance transfer tool 1 was a formulation, fluid substances other than a formulation (for example, nutritional composition, blood, adhesive, etc.) It is also possible to apply the present invention in the same way when handling

本発明は、流動性物質を移送する工程を含む各種の産業に広く適用することができる。   The present invention can be widely applied to various industries including a step of transferring a fluid substance.

1 流動性物質移送具
3 シリンジ
31 外筒
31a 内壁面
32 プランジャ
33 プランジャ本体
34 プランジャ頭部
34a 先端周縁部
35 弾性片
35a 当接部
35b 湾曲面部
35c 傾斜面部
36 溝
DESCRIPTION OF SYMBOLS 1 Fluid substance transfer tool 3 Syringe 31 Outer cylinder 31a Inner wall surface 32 Plunger 33 Plunger main body 34 Plunger head 34a Tip peripheral part 35 Elastic piece 35a Contact part 35b Curved surface part 35c Inclined surface part 36 Groove

Claims (8)

流動性物質を収容する外筒内にプランジャが往復動自在に挿着され、前記プランジャを引くことにより、前記外筒の外部から内部へ前記流動性物質を吸引するとともに、前記プランジャを押すことにより、前記外筒の内部から外部へ前記流動性物質を押し出すシリンジであって、
前記プランジャは、プランジャ本体と、このプランジャ本体の先端に一体に設けられ、前記外筒の内壁面に対して液密性を保持しながら摺動するプランジャ頭部とを有し、
前記プランジャ頭部の先端周縁部には、前記プランジャが前記外筒内に挿着された状態で当該外筒の内壁面に弾性的に接触し、前記プランジャが押されたときに比べて、前記プランジャが引かれたときに、前記外筒の内壁面に対する抵抗値が減少する環状の弾性片が前方に向けて延設されていることを特徴とするシリンジ。
A plunger is removably inserted into an outer cylinder containing a fluid substance, and by pulling the plunger, the fluid substance is sucked from the outside to the inside of the outer cylinder, and the plunger is pushed. A syringe for extruding the fluid substance from the inside of the outer cylinder to the outside,
The plunger has a plunger main body and a plunger head that is integrally provided at a tip of the plunger main body and slides while maintaining liquid tightness with respect to the inner wall surface of the outer cylinder,
Compared to the case where the plunger is elastically contacted with the inner wall surface of the outer cylinder in a state where the plunger is inserted into the outer cylinder and the plunger is pushed, The syringe is characterized in that an annular elastic piece that extends in a forward direction and has a resistance value that decreases with respect to the inner wall surface of the outer cylinder when the plunger is pulled.
前記プランジャが引かれたときは、前記外筒内の圧力が低下して、前記弾性片と前記外筒の前記内壁面との接圧が減少することにより、前記抵抗値が減少し、
前記プランジャが押されたときは、前記外筒内の圧力が上昇して、前記弾性片と前記外筒の前記内壁面との接圧が増大することにより、前記液密性が増大する、
ように構成されたことを特徴とする請求項1に記載のシリンジ。
When the plunger is pulled, the pressure in the outer cylinder is reduced, and the contact pressure between the elastic piece and the inner wall surface of the outer cylinder is reduced, thereby reducing the resistance value.
When the plunger is pushed, the pressure in the outer cylinder rises, and the contact pressure between the elastic piece and the inner wall surface of the outer cylinder increases, thereby increasing the liquid tightness.
The syringe according to claim 1, which is configured as described above.
前記弾性片は、前記プランジャ頭部の先端周縁部に所定形状の溝が形成されることによって当該溝の外側に設けられていることを特徴とする請求項2に記載のシリンジ。   The syringe according to claim 2, wherein the elastic piece is provided outside the groove by forming a groove having a predetermined shape in a peripheral edge portion of the tip of the plunger head. 前記溝は、略V形断面を有していることを特徴とする請求項3に記載のシリンジ。   The syringe according to claim 3, wherein the groove has a substantially V-shaped cross section. 前記弾性片は、前記プランジャが前記外筒内に挿着された状態で、当該外筒の前記内壁面に環状にほぼ線接触する当接部を有することを特徴とする請求項1に記載のシリンジ。   The said elastic piece has the contact part which contact | connects the said inner wall surface of the said outer cylinder substantially linearly in the state by which the said plunger was inserted in the said outer cylinder, The said contact piece is characterized by the above-mentioned. Syringe. 前記弾性片が、
前記当接部と、
前記当接部の後方に形成され、該当接部よりも小径で、且つ、外周面が前記プランジャの長手方向に沿って湾曲した湾曲面部と、
前記当接部の前方に形成され、該当接部よりも小径で、且つ、外周面が前記プランジャの前記長手方向に沿って傾斜した傾斜面と、
を備えることを特徴とする請求項5に記載のシリンジ。
The elastic piece is
The contact portion;
A curved surface portion formed behind the contact portion, having a smaller diameter than the corresponding contact portion, and having an outer peripheral surface curved along the longitudinal direction of the plunger;
An inclined surface that is formed in front of the contact portion, has a smaller diameter than the corresponding contact portion, and an outer peripheral surface that is inclined along the longitudinal direction of the plunger;
The syringe according to claim 5, comprising:
前記流動性物質が製剤であることを特徴とする請求項1乃至6のいずれかに記載のシリンジ。   The syringe according to any one of claims 1 to 6, wherein the fluid substance is a preparation. 三方弁と、該三方弁の第1の分岐流路接続されたシリンジと、該三方弁の第2の分岐流路に取り付けられた、流動性物質を収容する容器に接続される容器連結部と、該三方弁第3の分岐流路接続された接続管とを備え、
前記シリンジは、
流動性物質を収容する外筒内にプランジャが往復動自在に挿着され、前記プランジャを引くことにより、前記外筒の外部から内部へ前記流動性物質を吸引するとともに、前記プランジャを押すことにより、前記外筒の内部から外部へ前記流動性物質を押し出すように構成され、
前記プランジャは、プランジャ本体と、このプランジャ本体の先端に一体に設けられ、前記外筒の内壁面に対して液密性を保持しながら摺動するプランジャ頭部とを有し、
前記プランジャ頭部の先端周縁部には、前記プランジャが前記外筒内に挿着された状態で当該外筒の内壁面に弾性的に接触し、前記プランジャが押されたときに比べて、前記プランジャが引かれたときに、前記外筒の内壁面に対する抵抗値が減少する環状の弾性片が前方に向けて延設されていることを特徴とする流動性物質移送具。
A three-way valve, a syringe connected to the first branch flow path of the three-way valve, and a container connecting part attached to a container containing a fluid substance attached to the second branch flow path of the three-way valve; A connecting pipe connected to the third branch flow path of the three-way valve,
The syringe is
A plunger is removably inserted into an outer cylinder containing a fluid substance, and by pulling the plunger, the fluid substance is sucked from the outside to the inside of the outer cylinder, and the plunger is pushed. , Configured to extrude the fluid substance from the inside of the outer cylinder to the outside,
The plunger has a plunger main body and a plunger head that is integrally provided at a tip of the plunger main body and slides while maintaining liquid tightness with respect to the inner wall surface of the outer cylinder,
Compared to the case where the plunger is elastically contacted with the inner wall surface of the outer cylinder in a state where the plunger is inserted into the outer cylinder and the plunger is pushed, A fluid substance transfer device, wherein an annular elastic piece whose resistance value against the inner wall surface of the outer cylinder decreases when the plunger is pulled is extended forward.
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