JPWO2014111990A1 - Probe, spectroscopic measurement device, and diagnostic system - Google Patents

Abstract

The probe (10) is arranged in front of the emission end face of the irradiation optical fiber (110), and of the light output from the irradiation optical fiber (110), the wavelength of the measurement light for irradiating the measurement target site in the lumen Of the radiated light emitted from the measurement target part when the measurement target part is irradiated with the measurement light, which is disposed in front of the incident end face of the optical filter (141) that transmits the component and the optical fiber for light reception (120) An optical filter (142) that transmits a wavelength component other than the wavelength of the measurement light, and a flat plate that is disposed between the optical filter (141) and the optical filter (142) and has a light shielding property to the measurement light and the emitted light. And a light shielding member (143) having a shape.

Description

  The present invention relates to a probe used for measuring a measurement target site in a body lumen by spectroscopy, and a spectroscopic measurement device connectable to the probe.

  When measuring a measurement target site of a body lumen (hereinafter simply referred to as a “lumen”) by spectroscopy (spectrometry), a long probe is introduced into the lumen via the endoscope channel, Performing light projection and light reception using a probe is conventionally known.

  In spectroscopic measurement of a measurement target region, generally, a relatively narrow-band excitation light (hereinafter referred to as “measurement light”) is irradiated to the measurement target region via a probe, and appears from a measurement target region in a wavelength region different from that of the measurement light. Radiation light including fluorescence or Raman scattered light (hereinafter referred to as “measurement target light”) is emitted, and this radiation light is received by the probe. The light received by the probe is detected by a spectroscopic measurement device connected to the probe. Spectral data obtained as a detection result can be used to determine the state of a lesion or the like of a measurement target site.

  Usually, the intensity of the measurement target light (that is, fluorescence or Raman scattered light) contained in the emitted light from the measurement target site is significantly lower than the intensity of the measurement light, so the high-intensity measurement light and the low-intensity measurement target light And detecting only the measurement target light. For this purpose, an optical filter may be installed in a probe that uses both an optical fiber for irradiating measurement light (irradiation optical fiber) and an optical fiber for receiving measurement target light (optical fiber for light reception). For example, an optical filter that passes only the wavelength of measurement light (irradiation optical filter) is installed near the tip of the optical fiber for irradiation, and an optical filter that cuts only the wavelength of measurement light (optical filter for light reception) is used for light reception. Install near the tip of the optical fiber.

  Even in the case where an optical filter is installed as described above in a probe that uses both an irradiation optical fiber and a light receiving optical fiber, crosstalk between these fibers may be a problem. That is, extremely weak light leaking from the irradiation optical fiber may enter the light receiving optical fiber, and a part of the light may be conducted in the light receiving optical fiber. This light is very small of the light conducted through the irradiation optical fiber, but usually the optical signal itself of the measurement target light to be detected is very small, so that it has the same intensity as this optical signal. Sometimes.

  As a light-shielding structure for preventing such crosstalk, for example, there is one proposed in Patent Document 1. In the probe described in Patent Document 1, a light receiving optical fiber is disposed around an irradiation optical fiber. The tip of the optical fiber for irradiation is covered with a stainless steel pipe for shielding light between the fibers, but a part of this pipe protrudes forward from the tip of the fiber, and an optical filter for irradiation is inserted there. Has been. The light receiving optical filter disposed at the tip of the light receiving optical fiber is formed in a donut shape and is disposed so as to surround the outer periphery of the pipe. With this structure, the irradiation side and the light receiving side are completely separated from each other.

JP 2004-294109 A

  By the way, the NA (Numerical Aperture) of an optical fiber is generally about 0.2 to 0.6 although it depends on the material. That is, the light (including measurement light) emitted from the irradiation optical fiber is divergent light, and the measurement target light incident on the light receiving optical fiber is convergent light.

  Therefore, in the probe described in Patent Document 1, since the measurement light emitted from the irradiation optical fiber diverges in the centrifugal direction of the irradiation optical fiber, the measurement light hits the inner peripheral surface of the pipe sheathed on the irradiation optical fiber and is reflected. . Of the emitted measurement light, a portion that goes straight without hitting the inner peripheral surface of the pipe can be easily propagated toward the measurement target portion. On the other hand, a portion of the emitted measurement light that reflects when it hits the inner peripheral surface of the pipe propagates in a direction different from that of the straight-advancing portion described above. Therefore, the light intensity of the measurement light applied to the measurement target region is insufficient, and the light intensity of the measurement target light may be insufficient accordingly.

  If the pipe is shortened in order to reduce reflection by the pipe, it is necessary to make the glass plate used for the optical filter thin. However, when the glass plate is thinned, its strength is lowered, and it is difficult to manufacture an optical filter.

  In the probe described in Patent Document 1, an optical filter formed in a donut shape so as to surround the pipe is used. However, the donut optical filter is difficult to manufacture and is expensive.

  Here, in the probe described in Patent Document 1, it is assumed that the position of the irradiation optical fiber and the position of the light receiving optical fiber are interchanged. That is, here, it is assumed that the pipe is covered with the light receiving optical fiber. In this case, the outer peripheral portion of the light incident on the light receiving optical fiber capable of receiving the light that converges in the center direction is shielded by the pipe that is sheathed on the light receiving optical fiber, and is sufficient for the outer peripheral portion of the incident end face of the light receiving optical fiber. The amount of light is not incident (vignetting phenomenon). Therefore, the light intensity of the measurement target light may be insufficient.

  As described above, in the structure using the pipe-shaped metal member for shielding light between the irradiation side and the light receiving side, there is a problem that it is difficult to manufacture an optical filter, and the irradiation efficiency of the measurement light and the light reception efficiency of the measurement target light There was a certain limit to the improvement.

  An object of the present invention is to provide a probe, a spectroscopic measurement apparatus, and a diagnostic system that can easily manufacture a filter and that can improve the irradiation efficiency of measurement light and the light reception efficiency of measurement target light.

The probe according to the present invention comprises:
1st optics which is arrange | positioned ahead of the output end surface of a 1st optical fiber, and permeate | transmits the wavelength component of the measurement light for irradiating the measurement object site | part of a body lumen among the lights output from the said 1st optical fiber A filter,
Wavelength components other than the wavelength of the measurement light out of the radiated light emitted from the measurement target site when the measurement target site is irradiated with the measurement light, arranged in front of the incident end face of the second optical fiber. A second optical filter that passes through;
A flat light-shielding member that is disposed between the first optical filter and the second optical filter and has a light-shielding property with respect to the measurement light and the radiated light;
Have

The spectrometer of the present invention is
Spectral processing is performed on the light that can be connected to the probe and has passed through the second optical filter of the probe.

The diagnostic system of the present invention comprises:
And a spectroscopic measurement device connected to the probe for performing spectroscopic processing on the light transmitted through the second optical filter of the probe.

  According to the present invention, it is possible to provide an optical probe, a spectroscopic measurement apparatus, and a diagnostic system that are easy to manufacture a filter and that can improve the irradiation efficiency of measurement light and the light reception efficiency of measurement target light. .

It is a figure which shows the structure of the diagnostic system in this Embodiment. It is a perspective view of the front-end | tip part of the endoscope main body in this Embodiment. It is a figure which shows schematically the internal structure of the probe in this Embodiment. It is a figure which shows schematically the internal structure of the probe in this Embodiment. It is a disassembled perspective view which shows roughly the internal structure of the probe in this Embodiment. It is a disassembled perspective view which shows roughly the modification of the internal structure of the probe in this Embodiment. It is a disassembled perspective view which shows roughly the modification of the internal structure of the probe in this Embodiment. It is sectional drawing of the fixed frame member in this Embodiment. It is sectional drawing of the modification of the fixed frame member in this Embodiment. It is a disassembled perspective view which shows roughly the modification of the internal structure of the probe in this Embodiment.

Hereinafter, the present embodiment will be described in detail with reference to the drawings.
[Configuration of Diagnostic System 1]
A diagnostic system 1 shown in FIG. 1 includes an endoscope 2, an endoscope processor 3, a base unit 4, an input device 5, monitors 6 and 7, and a probe 10. The base unit 4 functions as a spectroscopic measurement device.

  The endoscope 2 is provided at a long flexible endoscope body 21 formed so as to be capable of being introduced into a lumen, and a proximal end portion (endoscope proximal end portion) 21a of the endoscope body 21. And the cable 23 that connects the endoscope main body 21 and the endoscope processor 3 via the operation unit 22 in a communicable manner.

  The endoscope main body 21 has flexibility that can be easily bent following the curvature of the lumen when entering the inside of the lumen over substantially the entire length of the endoscope main body 21. Further, the endoscope body 21 has a mechanism (not shown) capable of bending a predetermined range (operable portion 21c) on the endoscope distal end portion 21b side at an arbitrary angle in accordance with the operation of the knob 22a of the operation portion 22. Have

  The endoscope main body 21 includes a camera CA, a light guide LG, and a channel CH as shown in a perspective view (FIG. 2) of the endoscope distal end portion 21b. The light guide LG guides light (visible light) emitted from the illumination light source 31 of the endoscope processor 3 to the endoscope distal end portion 21b, and emits the light from the end face of the endoscope distal end portion 21b. The camera CA is an electronic camera equipped with a solid-state imaging device, images an area illuminated by light emitted from the light guide LG, and sends the signal (imaging signal) to the image processing unit 32 of the endoscope processor 3. To transmit. An image (endoscopic image) based on the transmitted imaging signal is displayed on the monitor 6. The channel CH is a lumen having a diameter of, for example, 2.6 [mm] formed in the endoscope main body 21 so as to communicate with the introduction port 22b formed in the operation unit 22. Various devices for observing, diagnosing, and operating a lesion can be inserted into the channel CH. In the present embodiment, as shown in FIG. 1, a lesion such as cancer is obtained by irradiating measurement light (excitation light) on a measurement target site in a lumen and acquiring radiation emitted from the measurement target site. It is possible to insert a probe main body 11 capable of inspecting the status of a lesioned part such as the presence / absence of a part, its type, and the degree of lesion progression.

  The probe main body 11 has an outer diameter (for example, 2.4 [mm]) that can be inserted into the channel CH of the endoscope 2, and is a long and flexible piece that extends from the probe proximal end portion 11a to the probe distal end portion 11b. It is a flexible linear member and is introduced into the lumen by insertion into the channel CH. The probe body 11 is connected to the base unit 4 via connectors 11c and 11d provided on the probe base end portion 11a. The probe body 11 guides the measurement light emitted from the laser 41 of the base unit 4 by the irradiation optical fiber 110 (see FIG. 3), and uses the measurement light as the irradiation light to the measurement target site in the lumen. Exit. The laser 41 is a semiconductor laser, a solid laser, or the like, but it is preferable to use a semiconductor laser from the viewpoint of downsizing the apparatus. The wavelength of the laser light is 400 to 410 [nm], 487 [nm], 630 to 660 [nm], 780 to 790 [nm], 830 to 860 [nm], 1290 to 1330 [nm] or 1520. A wavelength of ˜1580 [nm] is preferred. The light source of the measurement light may not be the laser 41, but may be an LED (Light Emitting Diode), a light bulb (for example, a xenon lamp or a halogen lamp), or the like.

  In addition, the probe body 11 receives the measurement target light (that is, fluorescence or Raman scattered light) included in the radiated light emitted from the measurement target part when the measurement target part is irradiated with the measurement light, and receives the optical fiber 120 for receiving light (FIG. 3 And the measurement target light is guided to the spectroscope 42 of the base unit 4. The measurement target light guided to the spectroscope 42 is subjected to spectrum analysis processing (spectral processing) by the spectroscope 42. The spectrum analysis result is subjected to image processing or the like by a CPU (Central Processing Unit) 43a of the computer 43 and displayed on the monitor 7 in the form of a graph or the like. The CPU 43a may determine a medical condition and the like, and the determination result may be stored in the memory 43b and displayed on the monitor 7. The execution and setting of various analyzes and determinations in the computer 43 can be performed by operating the input device 5 (for example, a keyboard or a mouse).

  3A is a diagram schematically showing the internal configuration of the probe 10 shown in FIG. FIG. 4 is an exploded perspective view schematically showing the internal configuration of the probe 10.

  The irradiation optical fiber 110 (first optical fiber) and the light receiving optical fiber 120 (second optical fiber) are both long linear members having a total length of several meters and an outer diameter of about 100 to 300 [μm]. It is stored in. The irradiation optical fiber 110 is optically connected to the laser 41 of the base unit 4 by the connector 11c of the probe base end portion 11a. The light receiving optical fiber 120 is optically connected to the spectroscope 42 of the base unit 4 by a connector 11d of the probe base end portion 11a.

  The tip region (fiber tip region) 111 of the irradiation optical fiber 110 and the tip region (fiber tip region) 121 of the light receiving optical fiber 120 are held by a ferrule 130 (holding unit) disposed behind the optical filters 141 and 142. Yes. Thereby, the irradiation optical fiber 110 and the light receiving optical fiber 120 form a bundle, and the emission end face (that is, the emission surface of the measurement light to the measurement target part) and the incident end face (that is, reception of the measurement target light from the measurement target part). Surface) is accurately positioned relative to the ferrule 130. The lengths of the fiber tip regions 111 and 121 held by the ferrule 130 are about 5 to 10 [mm].

  The ferrule 130 is a member made of an inorganic material such as metal, quartz glass, or zirconia. The ferrule 130 is formed with holes 130c and 130d into which the irradiation optical fiber 110 and the light receiving optical fiber 120 can be inserted. The irradiation optical fiber 110 and the light receiving optical fiber 120 are held by the ferrule 130 by being inserted into the holes 130c and 130d.

  The irradiation optical fiber 110 and the light receiving optical fiber 120 held by the ferrule 130 are disposed so as to form a bundle in contact with or close to each other for the purpose of improving the light receiving efficiency and reducing the diameter of the probe 11.

  The optical filter 141 (first optical filter) is located in the irradiation optical system including the irradiation optical fiber 110, and one end surface thereof is disposed in front of the emission end surface of the fiber tip region 111. The optical filter 141 has a configuration in which a light absorbing material (or light reflecting material) is dispersed in a transparent base material such as quartz glass, or a configuration in which a dielectric multilayer film is formed on a transparent substrate. Only wavelength components can be transmitted.

  The optical filter 142 (second optical filter) is located in the light receiving optical system including the light receiving optical fiber 120, and one end surface thereof is disposed in front of the incident end surface of the fiber tip region 121. The optical filter 142 has a configuration in which a light absorbing material (or a light reflecting material) is dispersed in a transparent base material such as quartz glass, or a configuration in which a dielectric multilayer film is formed on a transparent substrate. Wavelength components outside the wavelength range corresponding to the wavelength can be transmitted.

  In the present embodiment, from the viewpoint of manufacturing the optical filters 141 and 142 at a low cost, as shown in FIG. 4, the outer periphery of the optical filters 141 and 142 has a circular part cut off in a straight line, that is, a flat portion. It is formed in a D-cut shape having 141a, 142a and circular portions 141b, 142b.

  A lens 150 made of, for example, quartz glass or sapphire is disposed at the probe tip 11b in front of the optical filters 141 and 142. The lens 150 is equipped for the purpose of irradiating the measurement light to the outside, receiving the radiated light from the outside, and improving the air tightness and water tightness of the optical path. The lens 150 may be a plurality of lens groups.

  Between the optical filter 141 and the optical filter 142, a flat plate-shaped light shielding member 143 made of metal (for example, stainless steel) is disposed. More specifically, the light shielding member 143 is disposed so as to be sandwiched between the flat portion 141 a of the optical filter 141 and the flat portion 142 a of the optical filter 142. The light shielding member 143 has a light shielding property with respect to the measurement light irradiated to the measurement target part and the radiated light (including the measurement target light) emitted from the measurement target part. The thickness d of the light shielding member 143 is, for example, 0.01 to 0.1 [mm]. The front end surfaces of the optical filters 141 and 142 and the front end surface of the light shielding member 143 are arranged so that the positions in the probe longitudinal direction are aligned. By arranging the front end surfaces of the optical filters 141 and 142 and the front end surface of the light shielding member 143, more preferably, these members are arranged on the same surface so that these members are arranged closer to the lens 150. This contributes to making the probe 10 compact.

  The lens 150, the optical filters 141 and 142, and the ferrule 130 are accommodated in a metal holder 151 as shown in FIG. 3B. The holder 151 has a through hole of the same diameter inside, and a flange portion 151a that forms an opening having a smaller diameter than the through hole on the tip side. In addition, a connecting portion 151 b having a reduced outer diameter is provided on the rear end side of the holder 151. A lens 150, interval tubes 152 and 153 for adjusting the interval, optical filters 141 and 142, and a ferrule 130 are sequentially inserted into the through hole of the holder 151 from the rear end side, and the fixing member 154 is inserted into the connection portion 151b of the holder 151. Each member is fixed to the holder 151 by fitting into the holder 151. Then, the holder 151 and the tube member 155 are covered by covering the connection portion 151b at the rear end of the holder 151 with a flexible resin tube member 155 so as to cover the optical fibers 110 and 120 and the fixing member 154. Connecting. Thus, the probe 10 is assembled.

[Effects of the present embodiment]
As described above in detail, the probe 10 according to the present embodiment is disposed in front of the emission end face of the irradiation optical fiber 110 and irradiates the measurement target site in the lumen out of the light output from the irradiation optical fiber 110. The optical filter 141 that transmits the wavelength component of the measurement light and the radiation light that is disposed in front of the incident end face of the light receiving optical fiber 120 and is emitted from the measurement target portion when the measurement target portion is irradiated with the measurement light Among them, an optical filter 142 that transmits a wavelength component other than the measurement light, and a flat plate-shaped light shielding member 143 that is disposed between the optical filter 141 and the optical filter 142 and has a light shielding property with respect to the measurement light and the emitted light. Have

  According to the present embodiment configured as described above, the outer peripheral portions of the optical filters 141 and 142 are covered only by a very small part (flat portions 141a and 142a) in contact with the light shielding member 143, and almost all the circumferences. It is kept exposed to the outside. Therefore, when the measurement light that diverges in the centrifugal direction of the irradiation optical fiber 110 passes through the optical filter 141, the measurement light reflected by the light shielding member 143 is minimized, and most of the measurement light is directed toward the measurement target region. Will go straight ahead. Therefore, a sufficient amount of measurement light is irradiated to the measurement target part, and the irradiation efficiency of the measurement light can be improved. Further, when the measurement target light included in the radiated light emitted from the measurement target region passes through the optical filter 142, the measurement target light reflected by the light shielding member 143 is minimized, and most of the measurement target light is The light travels straight toward the incident end face of the light receiving optical fiber 120. Accordingly, a sufficient amount of measurement target light is incident on the incident end face of the light receiving optical fiber 120, and the light receiving efficiency of the measurement target light can be improved. In addition, since the emission end face of the irradiation optical fiber 110 and the incidence end face of the light receiving optical fiber 120 are arranged side by side in a direction perpendicular to the probe longitudinal direction, the optical filters 141 and 142 are arranged in a part of a circle. Can be made into a D-cut shape cut out linearly. An optical filter can be easily produced as compared with a donut shape as described in the above-mentioned prior art document if it is a relatively simple shape that can be cut in such a straight line.

[Modification]
In the above embodiment, the example in which the tip surface of the light shielding member 143 and the tip surfaces of the optical filters 141 and 142 are arranged so as to be aligned in the probe longitudinal direction has been described. It is not limited to. For example, the front end surface of the light shielding member 143 may be disposed so as to protrude from the front end surfaces of the optical filters 141 and 142. With this configuration, it is possible to prevent part of the measurement light that has passed through the optical filter 141 from being diffracted and incident on the optical filter 142 and conducted through the light receiving optical fiber 120. However, from the viewpoint of minimizing the measurement light reflected by the light shielding member 143, it is preferable that the distal end surface of the light shielding member 143 is not excessively projected from the distal end surfaces of the optical filters 141 and 142, for example, 0 at the maximum. It is preferable to make it project by 1 [mm].

  In the above embodiment, when the optical filters 141 and 142 are disposed inside the probe 10, as shown in FIG. 5A, a fixed frame member 160 that fixes the outer periphery of the optical filters 141 and 142 is used. Also good. FIG. 5B is a front view of the fixed frame member 160 (a view of the fixed frame member 160 viewed from behind). The fixed frame member 160 includes a cylindrical outer wall portion 160b that covers the circular portions 141b and 142b of the optical filters 141 and 142, flange portions 160a and 160c that face the distal end surface of the ferrule 130 and have openings 160d and 160e, respectively. Have The light shielding member 143 is erected near the center in the fixed frame member 160. The light shielding member 143 and the fixed frame member 160 may be formed integrally or separately. The flange portions 160 a and 160 c of the fixed frame member 160 have an area larger than the optical path of the optical filters 141 and 142. A transmissive member that transmits light over all wavelengths may be disposed between the flange portion 160a and the optical filter 141 and between the flange portion 160c and the optical filter 142.

  In the above embodiment, as shown in FIG. 6, in the state where the circular portions 141 b and 142 b of the optical filters 141 and 142 are fixed to the fixed frame member 160, the optical filters 141 and 142 are fixed to the fixed frame member 160. The fixing frame member may be caulked and fixed by caulking portions 163 and 164 provided on the fixing frame member. In the above embodiment, as shown in FIG. 7, the optical filters 141 and 142 are fitted into the inner peripheral portion of the fixed frame member 160, and the convex portions 165 a, 165 b, By engaging 166a and 166b with concave portions 141c, 141d, 142c, and 142d formed in the circular portions 141b and 142b of the optical filters 141 and 142, respectively, the circular portions 141b and 142b of the optical filters 141 and 142 are engaged. May be fixed to the fixed frame member 160. It should be noted that the concave portions formed on the inner peripheral portion of the fixed frame member 160 and the convex portions formed on the circular shaped portions 141b and 142b of the optical filters 141 and 142 are engaged with each other, whereby the circles of the optical filters 141 and 142 are obtained. The shape parts 141b and 142b may be fixed to the fixed frame member 160. From the viewpoint of improving the productivity of the optical filters 141 and 142 and the fixed frame member 160, the configuration shown in FIG. This is because no additional processing (concave portions 141c, 141d, 142c, 142d) is required for the optical filters 141, 142, and the manufacturing becomes easy.

  In the above embodiment, as shown in FIG. 8, the rear end portion of the light shielding member 143 is located at a position that does not overlap the exit end surface of the irradiation optical fiber 110 and the incident end surface of the light receiving optical fiber 120 on the front end surface of the ferrule 130. An attachment groove 148 that can be attached to the ferrule 130 by inserting 143a may be formed. With this configuration, the light shielding member 143 with respect to the front end surface of the ferrule 130 is disposed so that the rear end portion 143a of the light shielding member 143 is not positioned in front of the emission end face of the irradiation optical fiber 110 and the incident end face of the light receiving optical fiber 120. Can be reliably positioned.

  In addition, each of the above-described embodiments is merely an example of actualization in carrying out the present invention, and the technical scope of the present invention should not be construed as being limited thereto. That is, the present invention can be implemented in various forms without departing from the gist or the main features thereof.

  The disclosure of the specification, drawings, and abstract included in the Japanese application of Japanese Patent Application No. 2013-008397 filed on Jan. 21, 2013 is incorporated herein by reference.

DESCRIPTION OF SYMBOLS 1 Diagnostic system 2 Endoscope 3 Endoscope processor 4 Base unit 5 Input device 6,7 Monitor 10 Probe 11 Probe main body 11a Probe base end 11b Probe tip 11c, 11d Connector 110 Irradiation optical fiber 111, 121 Fiber tip region 120 Light receiving optical fiber 130 Ferrule 130c, 130d Hole 141, 142 Optical filter 141a, 142a Flat part 141b, 142b Circular part 141c, 141d, 142c, 142d Concave part 143 Light shielding member 143a Rear end part 148 Mounting groove 150 Lens 151a Flange Portion 151b Connection portion 152, 153 Spacing tube 154 Fixing member 155 Tube member 160 Fixing frame member 160a, 160c Flange portion 160b Outer wall portion 63,164 caulking portion 165a, 165b, 166a, 166b the convex portion

Claims (10)

1st optics which is arrange | positioned ahead of the output end surface of a 1st optical fiber, and permeate | transmits the wavelength component of the measurement light for irradiating the measurement object site | part of a body lumen among the lights output from the said 1st optical fiber A filter,
Wavelength components other than the wavelength of the measurement light out of the radiated light emitted from the measurement target site when the measurement target site is irradiated with the measurement light, arranged in front of the incident end face of the second optical fiber. A second optical filter that passes through;
A flat light-shielding member that is disposed between the first optical filter and the second optical filter and has a light-shielding property with respect to the measurement light and the radiated light;
Having a probe.   2. The probe according to claim 1, wherein the tip surface of the light shielding member and the tip surfaces of the first and second optical filters are arranged with their positions in the probe longitudinal direction aligned.   The probe according to claim 1, wherein a tip surface of the light shielding member is disposed so as to protrude from the tip surfaces of the first and second optical filters.   The probe according to any one of claims 1 to 3, further comprising a cylindrical fixing frame member that is disposed inside the probe and fixes outer peripheral portions of the first and second optical filters.   The probe according to claim 4, wherein the light shielding member is erected in the fixed frame member.   The probe according to claim 5, wherein the first and second optical filters are caulked and fixed to the fixed frame member by caulking portions provided on the fixed frame member. Of the inner peripheral part of the fixed frame member and the outer peripheral parts of the first and second optical filters, a convex part is formed on one side, and a concave part is formed on the other side.
The probe according to claim 5, wherein outer peripheral portions of the first and second optical filters are fixed to the fixed frame member by engaging the convex portion and the concave portion. A holding portion that is disposed behind the first and second optical filters and holds the first and second optical fibers;
The rear end portion of the light shielding member can be inserted and attached to the holding portion at a position that does not overlap with the emission end surface of the first optical fiber and the incident end surface of the second optical fiber in the front end surface of the holding portion. The probe according to any one of claims 1 to 3, wherein an attachment groove is formed.   A spectroscopic measurement apparatus that is connectable to the probe according to any one of claims 1 to 8 and that performs spectroscopic processing on light that has passed through the second optical filter of the probe.   A probe according to any one of claims 1 to 8, and a spectroscopic measurement device connected to the probe, wherein the light is transmitted through the second optical filter of the probe. A diagnostic system.

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