JPWO2005121745A1 - Biochemistry container - Google Patents

Biochemistry container Download PDF

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JPWO2005121745A1
JPWO2005121745A1 JP2006514510A JP2006514510A JPWO2005121745A1 JP WO2005121745 A1 JPWO2005121745 A1 JP WO2005121745A1 JP 2006514510 A JP2006514510 A JP 2006514510A JP 2006514510 A JP2006514510 A JP 2006514510A JP WO2005121745 A1 JPWO2005121745 A1 JP WO2005121745A1
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shape
glass plate
retaining frame
container
biochemical
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藤田　浩示
浩示 藤田
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Nippon Sheet Glass Co Ltd
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50855—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates

Abstract

多数のウェルを備えた生化学用容器を光透過性ガラスにより形成し、しかも、その生化学用容器の厚みを極端に薄くしても、所望どおりの形状を保持することができ、かつ、きわめて小さな外力で簡単に破損するおそれの少ない生化学用容器の提供。
平面視において矩形で、多数のウェル３を備えて光透過性材料で形成されている生化学用容器であって、生化学用容器が、平面視において矩形で、多数のウェル３を備えてガラスで形成されたガラスプレート１と、そのガラスプレート１の形状を保持する保形枠２とで構成され、その保形枠２がガラスプレート１の少なくとも相対向する２辺に沿って連結配置されている。A biochemical container having a large number of wells is formed of light-transmissive glass, and even if the biochemical container is extremely thin, the desired shape can be maintained, and Providing biochemical containers that are less likely to be easily damaged by a small external force.
1. A biochemical container, which is rectangular in a plan view and has a large number of wells 3 and which is made of a light-transmissive material, wherein the biochemical container is rectangular in a plan view and has a large number of wells 3. The glass plate 1 formed by 1. and the shape-retaining frame 2 that holds the shape of the glass plate 1, and the shape-retaining frame 2 is connected and arranged along at least two opposite sides of the glass plate 1. There is.

Description

本発明は、平面視において矩形で、多数のウェルを備えて光透過性材料で形成されている生化学用容器に関する。 The present invention relates to a biochemical container that is rectangular in a plan view and that is provided with a large number of wells and is made of a light transmissive material.

このような生化学用容器としては、例えば、マイクロプレートがあり、従来、ポリスチレンのような合成樹脂により一体的に形成されたもの（例えば、特許文献１参照）が知られている。また、マイクロプレートを本体と底板とに分割して、本体をポリスチレンで形成し、底板を合成石英板（石英ガラス）で形成して、ポリスチレン製の本体と合成石英板からなる底板とを接着剤で接着して形成したもの（例えば、特許文献２参照）などが知られている。   As such a biochemical container, for example, there is a microplate, and conventionally, a container integrally formed of a synthetic resin such as polystyrene (for example, see Patent Document 1) is known. Further, the microplate is divided into a main body and a bottom plate, the main body is made of polystyrene, the bottom plate is made of synthetic quartz plate (quartz glass), and the polystyrene main body and the bottom plate made of synthetic quartz plate are bonded by an adhesive. There are known ones formed by adhering with each other (for example, see Patent Document 2).

ところで、最近、逆ミセルの特異環境中でＤＮＡのハイブリダイゼーション挙動を紫外線分光測定により観察する遺伝子解析方法が提案され、注目もされている。前記遺伝子解析方法では、試料としてイソオクタンなどの有機溶剤が用いられる。
しかし、ポリスチレンなどの合成樹脂で一体的に形成されたものや、ポリスチレン製の本体を有する生化学用容器を用いた場合には、前記本体、接着剤等が有機溶剤によって溶解する可能性がある。このため、耐有機溶剤性に優れた生化学用容器の必要性が高まってきた。By the way, recently, a gene analysis method for observing the hybridization behavior of DNA by ultraviolet spectroscopy in a specific environment of reverse micelles has been proposed and attracted attention. In the gene analysis method, an organic solvent such as isooctane is used as a sample.
However, when a synthetic resin such as polystyrene is integrally formed, or when a biochemical container having a polystyrene main body is used, the main body, adhesive, etc. may be dissolved by an organic solvent. .. Therefore, there has been an increasing need for a biochemical container having excellent organic solvent resistance.

そこで、本出願人は、光透過性のガラス素材を軟化点以上に加熱し、溶融状態あるいは軟化状態にある光透過性ガラス素材を型枠内に入れて成形し、その後、分光測定が可能なように、各ウェル内の底面を研磨処理して製造した光透過性ガラスからなる生化学用容器を提案した（例えば、特許文献３参照）。
特開平１０−７８３８８号公報 特開２００２−１２５６５６号公報 特開２００４−１０９１０７号公報 Therefore, the applicant of the present invention heats a light-transmissive glass material to a softening point or higher, molds the light-transmissive glass material in a molten state or a softened state into a mold, and then performs spectroscopic measurement. As described above, a biochemical container made of light-transmissive glass manufactured by polishing the bottom surface of each well has been proposed (see, for example, Patent Document 3).
JP, 10-78388, A JP, 2002-125656, A JP 2004-109107 A

しかし、上記特許文献３に記載の生化学用容器では、容器全体が一枚のガラスのみにより形成されているので、容器の厚みを極端に薄くすることは事実上不可能である。
すなわち、容器の厚みを薄くするほど、光透過性が向上し、かつ、蛍光の発光などによる外乱の影響も少なくなるため、より一層厳密な測定が可能になる。しかし、例えば、容器の厚みを従来のプレパラート程度、具体的には、１ｍｍ以下にすると、実際の取り扱いにおいて、生化学用容器の保形性が大きな問題となる。また、きわめて小さな外力で簡単に破損してしまうという問題も生じる。However, in the biochemical container described in Patent Document 3, since the entire container is formed of only one piece of glass, it is virtually impossible to make the container extremely thin.
That is, as the thickness of the container is reduced, the light transmittance is improved, and the influence of disturbance due to the emission of fluorescence is reduced, so that more strict measurement can be performed. However, for example, if the thickness of the container is set to the level of a conventional preparation, specifically, 1 mm or less, the shape retention of the biochemical container becomes a serious problem in actual handling. In addition, there is a problem that it is easily damaged by an extremely small external force.

本発明は、このような従来の問題点に着目したものである。
その目的は、多数のウェルを備えた生化学用容器を光透過性ガラスにより形成し、しかも、その生化学用容器の厚みを極端に薄くしても、所望どおりの形状を保持することができ、かつ、きわめて小さな外力で簡単に破損するおそれの少ない生化学用容器を提供することである。The present invention focuses on such conventional problems.
The purpose is to form a biochemical container with a large number of wells from a light-transmissive glass, and to keep the desired shape even if the thickness of the biochemical container is extremely thin. In addition, it is to provide a biochemical container that is unlikely to be easily damaged by an extremely small external force.

本発明の第１の特徴構成は、平面視において矩形で、多数のウェルを備えて光透過性材料で形成されている生化学用容器であって、前記生化学用容器が、平面視において矩形で、多数のウェルを備えてガラスで形成されたガラスプレートと、そのガラスプレートの形状を保持する保形枠とで構成され、その保形枠が前記ガラスプレートの少なくとも相対向する２辺に沿って連結配置されているところにある。   A first characteristic configuration of the present invention is a biochemical container that is rectangular in a plan view and is formed of a light transmissive material with a large number of wells, wherein the biochemical container is a rectangle in a plan view. A glass plate formed of glass with a large number of wells, and a shape retention frame for retaining the shape of the glass plate, the shape retention frame being provided along at least two opposite sides of the glass plate. It is in the place where it is connected and arranged.

本発明の第１の特徴構成によれば、保形枠がガラスプレートの少なくとも相対向する２辺に沿って連結配置されているので、たとえガラスプレートの厚みを極端に薄く、例えば、１．０ｍｍ以下にしても、前記保形枠によって、ガラスプレートの形状は所望どおりに保持される。
それに加えて、ガラスプレートの２辺に沿う保形枠が、ガラスプレートを外力から保護する機能も果たすので、きわめて小さな外力で簡単に破損するおそれも少なく、実質的に一枚の光透過性ガラスからなる薄い生化学用容器を実際の使用に耐え得る状態で提供することができる。したがって、光透過性の向上と蛍光などによる外乱の抑制を図って、より一層厳密な測定が可能となる。According to the first characteristic configuration of the present invention, since the shape retention frames are connected and arranged along at least two opposite sides of the glass plate, the thickness of the glass plate is extremely thin, for example, 1.0 mm. Even in the following, the shape retaining frame holds the shape of the glass plate as desired.
In addition to that, the shape-retaining frame along the two sides of the glass plate also functions to protect the glass plate from external force, so that there is little risk of being easily broken by extremely small external force, and substantially one piece of light-transmissive glass. It is possible to provide a thin biochemical container consisting of the above in a state that can withstand actual use. Therefore, it is possible to perform more strict measurement by improving the light transmittance and suppressing the disturbance due to fluorescence or the like.

本発明の第２の特徴構成は、前記保形枠が、前記ガラスプレートの４辺に沿って連結配置されているところにある。   A second characteristic configuration of the present invention is that the shape retention frames are connected and arranged along the four sides of the glass plate.

本発明の第２の特徴構成によれば、保形枠が、ガラスプレートの４辺に沿って連結配置されているので、２辺に沿って連結配置されるのに比べて、保形枠によるガラスプレートの保形機能も外力からの保護機能も一層向上し、より一層実用的な生化学用容器の提供が可能となる。   According to the second characteristic configuration of the present invention, since the shape retention frame is connected and arranged along the four sides of the glass plate, the shape retention frame is connected by the shape retention frame as compared with the case where the shape retention frames are connected and arranged along the two sides. The shape retention function of the glass plate and the protection function from external force are further improved, and it becomes possible to provide a more practical biochemical container.

本発明の第３の特徴構成は、前記保形枠が、前記ガラスプレートの上面に当接する上側保形枠と下面に当接する下側保形枠とを備え、それら上側保形枠と下側保形枠が、前記ガラスプレートの縁部を上下から挟持する状態でガラスプレートに連結配置されているところにある。   According to a third characteristic configuration of the present invention, the shape retention frame includes an upper shape retention frame that contacts the upper surface of the glass plate and a lower shape retention frame that contacts the lower surface thereof. The shape-retaining frame is arranged so as to be connected to the glass plate while sandwiching the edge portion of the glass plate from above and below.

本発明の第３の特徴構成によれば、保形枠が、ガラスプレートの上面に当接する上側保形枠と下面に当接する下側保形枠を備え、それら上側保形枠と下側保形枠が、ガラスプレートの縁部を上下から挟持する状態でガラスプレートに連結配置されているので、ガラスプレートに対する保形枠の連結が確実となる。その上、たとえ生化学用容器を平坦な載置面上に置いても、ガラスプレートの下面が載置面に直接接触しないようにできる。したがって、生化学用容器の取り扱いが容易となり、また、その生化学用容器をそのまま上下に積み重ねることも可能となる。   According to the third characteristic configuration of the present invention, the shape retention frame includes an upper shape retention frame that abuts on the upper surface of the glass plate and a lower side shape retention frame that abuts on the lower surface of the glass plate. Since the shape frame is connected to the glass plate while sandwiching the edge of the glass plate from above and below, the shape retention frame is reliably connected to the glass plate. Moreover, even if the biochemical container is placed on a flat mounting surface, the lower surface of the glass plate can be prevented from directly contacting the mounting surface. Therefore, the biochemical container can be easily handled, and the biochemical containers can be stacked one above the other as they are.

本発明の第４の特徴構成は、前記上側保形枠と下側保形枠の一方が係合部を備え、他方が被係合部を備えていて、前記係合部と被係合部の係合によって、前記上側保形枠と下側保形枠が、前記ガラスプレートを挟持して互いに連結されているところにある。   According to a fourth characteristic configuration of the present invention, one of the upper shape retaining frame and the lower shape retaining frame includes an engaging portion and the other includes an engaged portion, and the engaging portion and the engaged portion. The upper shape-retaining frame and the lower shape-retaining frame are connected to each other by sandwiching the glass plate by the engagement.

本発明の第４の特徴構成によれば、上側保形枠と下側保形枠の一方が係合部を備え、他方が被係合部を備えていて、前記係合部と被係合部の係合によって、上側保形枠と下側保形枠が、ガラスプレートを挟持して互いに連結されているので、生化学用容器の製造時には、上側保持枠と下側保持枠に備えられた係合部と被係合部を使用することにより、ガラスプレートに対して両保持枠を容易に連結することができる。また、生化学用容器の使用時には、必要に応じて保持枠を外して、ガラスプレートのみでの使用も可能となる。   According to the fourth characteristic configuration of the present invention, one of the upper shape retaining frame and the lower shape retaining frame has an engaging portion and the other has an engaged portion, and the engaging portion and the engaged portion are engaged with each other. Since the upper shape retaining frame and the lower shape retaining frame are connected to each other by sandwiching the glass plate by the engagement of the parts, the upper shape retaining frame and the lower shape retaining frame are provided at the time of manufacturing the biochemical container. By using the engaging portion and the engaged portion, both holding frames can be easily connected to the glass plate. Further, when the biochemical container is used, the holding frame can be removed as necessary, and the glass plate can be used alone.

本発明による生化学容器の実施の形態を図に基づいて説明する。
本発明の生化学用容器は、図１乃至図３に示すように、光透過性のガラスで形成されたガラスプレート１と、そのガラスプレート１の形状を保形する合成樹脂製の保形枠２とで構成されている。
ガラスプレート１は、例えば、厚みｔが１ｍｍ〜０．３ｍｍ程度の非常に薄い石英ガラス板で形成され、その上面側には、例えば、エッチングにより形成された多数のウェル３を備えている。このガラスプレート１は、平面視において矩形、具体的には、例えば、長辺が約１２８ｍｍで短辺が約８６ｍｍ程度の長方形に形成されて、既存のマイクロプレートリーダーの使用が可能なように構成されている。
しかし、ガラスプレート１の寸法は、使用目的に応じて自由に設定することができる。例えば、プレパラートに対応するように、長辺が３インチ（約７６．２ｍｍ）で短辺が１インチ（約２５．４ｍｍ）の長方形に形成することもできる。An embodiment of a biochemical container according to the present invention will be described with reference to the drawings.
As shown in FIGS. 1 to 3, the biochemical container of the present invention includes a glass plate 1 formed of light-transmissive glass, and a shape-retaining frame made of a synthetic resin that holds the shape of the glass plate 1. 2 and.
The glass plate 1 is formed of, for example, a very thin quartz glass plate having a thickness t of about 1 mm to 0.3 mm, and has a large number of wells 3 formed by etching, for example, on its upper surface side. The glass plate 1 is formed in a rectangular shape in plan view, specifically, in a rectangular shape having a long side of about 128 mm and a short side of about 86 mm, for example, so that an existing microplate reader can be used. Has been done.
However, the dimensions of the glass plate 1 can be freely set according to the purpose of use. For example, a rectangle having a long side of 3 inches (about 76.2 mm) and a short side of 1 inch (about 25.4 mm) can be formed so as to correspond to a slide.

保形枠２は、図３に詳しく示すように、ガラスプレート１の４辺に沿ってガラスプレート１の上面に当接する額縁状の上側保形枠２ａと、同じくガラスプレート１の４辺に沿ってガラスプレート１の下面に当接する額縁状の下側保形枠２ｂで構成されている。
下側保形枠２ｂは、係合部として機能する複数個の係合用突起４を備え、その係合用突起４が、下側保形枠２ｂと一体的に形成されて側方へ向けて突設されている。
それに対し、上側保形枠２ａは、端部がＬ字状に構成されて、そのＬ字状の内側に下側保形枠２ｂの係合用突起４と対応する状態で被係合部として機能する複数個の係合用孔５が設けられている。As shown in detail in FIG. 3, the shape-retaining frame 2 includes a frame-shaped upper shape-retaining frame 2 a that abuts the upper surface of the glass plate 1 along the four sides of the glass plate 1, and also along the four sides of the glass plate 1. The lower shape-maintaining frame 2b is in the form of a frame and contacts the lower surface of the glass plate 1.
The lower shape retention frame 2b includes a plurality of engagement protrusions 4 that function as an engagement portion, and the engagement protrusions 4 are integrally formed with the lower shape retention frame 2b and protrude toward the side. It is set up.
On the other hand, the upper shape-retaining frame 2a has an L-shaped end portion, and functions as an engaged portion in a state corresponding to the engaging protrusion 4 of the lower shape-retaining frame 2b inside the L-shape. A plurality of engaging holes 5 are provided.

このような構成のガラスプレート１と保形枠２において、図３（ａ）に示すように、ガラスプレート１が下側保形枠２ｂの上面に載置され、そのガラスプレート１の上面に上側保形枠２ａが配置される。そして、図３（ｂ）に示すように、下側保形枠２ｂから突設の係合用突起４が上側保形枠２ａの係合用孔５に係合され、それによって、上側保形枠２ａと下側保形枠２ｂとが互いに連結されている。
前記連結によって、両保形枠２ａ，２ｂからなる保形枠２が、ガラスプレート１の４辺に沿ってその縁部を上下から挟持する状態で連結配置された状態となる。したがって、たとえガラスプレート１の厚みｔが１ｍｍ〜０．３ｍｍ程度の非常に薄いものであっても、ガラスプレート１の変形や割れなどが抑制される。また、前記ガラスプレート１をそのまま上下方向へ積み重ねることも可能で、取り扱いが容易となる。In the glass plate 1 and the shape-retaining frame 2 having such a configuration, as shown in FIG. 3A, the glass plate 1 is placed on the upper surface of the lower shape-retaining frame 2b, and the upper side of the upper surface of the glass plate 1 is placed. The shape retention frame 2a is arranged. Then, as shown in FIG. 3B, the engaging protrusions 4 projecting from the lower shape retaining frame 2b are engaged with the engaging holes 5 of the upper shape retaining frame 2a, whereby the upper shape retaining frame 2a. And the lower shape retention frame 2b are connected to each other.
By the above connection, the shape-retaining frame 2 composed of both the shape-retaining frames 2a and 2b is connected and arranged along the four sides of the glass plate 1 with the edges thereof sandwiched from above and below. Therefore, even if the thickness t of the glass plate 1 is very thin such as about 1 mm to 0.3 mm, the deformation and cracking of the glass plate 1 are suppressed. Further, the glass plates 1 can be stacked vertically as they are, which facilitates handling.

〔別実施形態〕
（１）先の実施形態の他に、複数枚のガラスプレート１と一組の保形枠２により生化学用容器を構成することもできる。
すなわち、図４に示すように、例えば、三枚のガラスプレート１を下側保形枠２ｂの上面に平行に並べて載置し、それらガラスプレート１の上面に配置した上側保形枠２ａによって、三枚のガラスプレート１を一緒に挟持して生化学用容器を構成することもできる。
また、図５に示すように、上述した三枚のガラスプレート１のうちの一枚だけを下側保形枠２ｂの上面に載置し、上側保形枠２ａによって挟持して生化学用容器を構成することもできる。この場合には、保形枠２がガラスプレート１の相対向する２辺に沿って連結配置されることになる。[Another embodiment]
(1) In addition to the above-described embodiment, a biochemical container can be configured by a plurality of glass plates 1 and a pair of shape retention frames 2.
That is, as shown in FIG. 4, for example, three glass plates 1 are placed in parallel on the upper surface of the lower shape retaining frame 2b, and the upper shape retaining frame 2a disposed on the upper surface of the glass plates 1 It is also possible to sandwich the three glass plates 1 together to form a biochemical container.
Further, as shown in FIG. 5, only one of the above-mentioned three glass plates 1 is placed on the upper surface of the lower shape retaining frame 2b, and is sandwiched by the upper shape retaining frame 2a to hold the biochemical container. Can also be configured. In this case, the shape-retaining frames 2 are connected and arranged along the two opposite sides of the glass plate 1.

（２）先の実施形態では、ガラスプレート１を石英ガラスで形成した例を示したが、石英ガラス以外にも、例えば、ソーダライムガラス、無アルカリガラス、ホウケイ酸ガラスなどの各種のガラスにより形成可能である。
そのガラスプレート１の上面に形成するウェル３に関しても、先の実施形態で示したエッチングに限るものではなく、例えば、レーザー加工やプレス加工により形成することができる。 また、保形枠２に関しても、先の実施形態で示した合成樹脂に限らず、例えば、金属や木製、あるいは、ガラスなどにより形成することもできる。(2) In the above embodiment, an example in which the glass plate 1 is made of quartz glass is shown, but other than quartz glass, for example, it is made of various glasses such as soda lime glass, alkali-free glass, and borosilicate glass. It is possible.
The well 3 formed on the upper surface of the glass plate 1 is not limited to the etching shown in the above embodiment, but may be formed by laser processing or press processing, for example. Further, the shape-retaining frame 2 is not limited to the synthetic resin described in the above embodiment, but may be formed of metal, wood, glass, or the like.

本発明は、生化学分野で生化学容器として利用可能である。特に、逆ミセルの特異環境中でＤＮＡのハイブリダイゼーション挙動を紫外線分光測定により観察する遺伝子解析方法等、有機溶剤存在下での紫外線分光測定の分野で用いる生化学用容器等として利用可能である。     INDUSTRIAL APPLICABILITY The present invention can be used as a biochemical container in the field of biochemistry. In particular, it can be used as a biochemical container used in the field of ultraviolet spectroscopy in the presence of an organic solvent, such as a gene analysis method of observing the hybridization behavior of DNA by ultraviolet spectroscopy in a specific environment of reverse micelles.

生化学用容器の分解斜視図Exploded perspective view of biochemistry container 生化学用容器の斜視図Biochemical container perspective view 生化学用容器の要部の断面図Sectional view of essential parts of biochemistry container 別の実施形態による生化学用容器の分解斜視図An exploded perspective view of a biochemical container according to another embodiment. 別の実施形態による生化学用容器の斜視図A perspective view of a biochemical container according to another embodiment

符号の説明Explanation of symbols

１ ガラスプレート
２ 保形枠
２ａ 上側保形枠
２ｂ 下側保形枠
３ ウェル
４ 係合部
５ 被係合部1 Glass Plate 2 Shape-Retaining Frame 2a Upper Shape-Retaining Frame 2b Lower Shape-Retaining Frame 3 Well 4 Engagement Part 5 Engaged Part

Claims (5)

平面視において矩形で、多数のウェルを備えて光透過性材料で形成されている生化学用容器であって、
前記生化学用容器が、平面視において矩形で、多数のウェルを備えてガラスで形成されたガラスプレートと、そのガラスプレートの形状を保持する保形枠とで構成され、その保形枠が前記ガラスプレートの少なくとも相対向する２辺に沿って連結配置されている生化学用容器。A container for biochemistry, which is rectangular in a plan view and is formed of a light-transmitting material with a large number of wells,
The biochemical container is rectangular in a plan view, and is composed of a glass plate formed of glass with a large number of wells, and a shape-retaining frame that holds the shape of the glass plate, and the shape-retaining frame is A container for biochemistry, which is connected and arranged along at least two opposite sides of a glass plate. 前記保形枠が、前記ガラスプレートの４辺に沿って連結配置されている請求項１に記載の生化学用容器。   The biochemical container according to claim 1, wherein the shape retention frames are connected and arranged along four sides of the glass plate. 前記保形枠が、前記ガラスプレートの上面に当接する上側保形枠と下面に当接する下側保形枠とを備え、それら上側保形枠と下側保形枠とが、前記ガラスプレートの縁部を上下から挟持する状態でガラスプレートに連結配置されている請求項１に記載の生化学用容器。   The shape-retaining frame comprises an upper shape-retaining frame that abuts the upper surface of the glass plate and a lower shape-retaining frame that abuts the lower surface, and the upper shape-retaining frame and the lower shape-retaining frame are of the glass plate. The biochemical container according to claim 1, wherein the biochemical container is arranged so as to be connected to the glass plate while sandwiching the edge portion from above and below. 前記保形枠が、前記ガラスプレートの上面に当接する上側保形枠と下面に当接する下側保形枠とを備え、それら上側保形枠と下側保形枠とが、前記ガラスプレートの縁部を上下から挟持する状態でガラスプレートに連結配置されている請求項２に記載の生化学用容器。   The shape-retaining frame includes an upper shape-retaining frame that contacts the upper surface of the glass plate and a lower shape-retaining frame that contacts the lower surface, and the upper shape-retaining frame and the lower shape-retaining frame are the glass plate. The biochemical container according to claim 2, wherein the biochemical container is arranged so as to be connected to the glass plate while sandwiching the edge portion from above and below. 前記上側保形枠と下側保形枠のうちの一方が係合部を備え、他方が被係合部を備えていて、前記係合部と被係合部との係合によって、前記上側保形枠と下側保形枠とが、前記ガラスプレートを挟持して互いに連結されている請求項３又は４に記載の生化学用容器。   One of the upper shape retaining frame and the lower shape retaining frame includes an engaging portion, and the other includes an engaged portion, and the upper portion is formed by engaging the engaging portion and the engaged portion. The biochemical container according to claim 3 or 4, wherein the shape-retaining frame and the lower shape-retaining frame are connected to each other with the glass plate interposed therebetween.
JP2006514510A 2004-06-11 2005-06-07 Biochemistry container Pending JPWO2005121745A1 (en)

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