JPS6490121A - Pharmaceutical for oral cavity having sustained release property - Google Patents

Pharmaceutical for oral cavity having sustained release property

Info

Publication number
JPS6490121A
JPS6490121A JP62248544A JP24854487A JPS6490121A JP S6490121 A JPS6490121 A JP S6490121A JP 62248544 A JP62248544 A JP 62248544A JP 24854487 A JP24854487 A JP 24854487A JP S6490121 A JPS6490121 A JP S6490121A
Authority
JP
Japan
Prior art keywords
water
high polymer
medicine
oral cavity
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62248544A
Other languages
Japanese (ja)
Other versions
JP2635336B2 (en
Inventor
Masaya Yamada
Ryoshi Konishi
Tatsuya Konishi
Tadafumi Mizobuchi
Takahiko Watou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teikoku Seiyaku Co Ltd
Original Assignee
Teikoku Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Seiyaku Co Ltd filed Critical Teikoku Seiyaku Co Ltd
Priority to JP62248544A priority Critical patent/JP2635336B2/en
Publication of JPS6490121A publication Critical patent/JPS6490121A/en
Application granted granted Critical
Publication of JP2635336B2 publication Critical patent/JP2635336B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

PURPOSE:To obtain the titled pharmaceutical consisting of a viscous layer containing a carboxylvinyl polymer and water-insoluble high polymer as main ingredients and medicine layer obtained by blending a water insoluble high polymer, water soluble high polymer, etc., with a medicine and capable of attaching to oral mucous membrane for long period and continuously releasing the medicine. CONSTITUTION:A medicine layer 2 obtained by blending a medicine with a water- insoluble high polymer such as vinyl acetate resin, a water-soluble high polymer such as hydroxypropylmethylcellulose and/or a water-decomposable high polymer such as hydroxypropyl-methyl-celluloseacetate succinate is laminated with an adhesive layer 1 containing carboxyl polymer such as polyacrylic acid, water-insoluble high polymer such as ethylcellulose as main ingredients to provide the pharmaceutical for oral cavity having sustained release property, closely and readily adhering to mucous membrane of oral cavity, free from influence from secretion liquid such as saliva, eating and drinking or talking, remaining in mucous membrane of oral cavity over a long period and simultaneously effectively and continuously releasing the agent and suitable to locally or sistemically continuous administration.
JP62248544A 1987-09-30 1987-09-30 Sustained release oral preparation Expired - Fee Related JP2635336B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62248544A JP2635336B2 (en) 1987-09-30 1987-09-30 Sustained release oral preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62248544A JP2635336B2 (en) 1987-09-30 1987-09-30 Sustained release oral preparation

Publications (2)

Publication Number Publication Date
JPS6490121A true JPS6490121A (en) 1989-04-06
JP2635336B2 JP2635336B2 (en) 1997-07-30

Family

ID=17179758

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62248544A Expired - Fee Related JP2635336B2 (en) 1987-09-30 1987-09-30 Sustained release oral preparation

Country Status (1)

Country Link
JP (1) JP2635336B2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03209326A (en) * 1990-01-11 1991-09-12 Teikoku Seiyaku Kk Nicotine-containing cataplasm for oral cavity membrane
JP2002512950A (en) * 1998-04-29 2002-05-08 バイロテックス コーポレイション Drug carrier device suitable for delivering drug compounds to mucosal surfaces
JP2005504763A (en) * 2001-08-16 2005-02-17 アクセス ファーマシューティカルズ， インコーポレイテッド Mucoadhesive corrosive drug delivery device for controlled administration of pharmaceuticals and other active compounds
JP2005289867A (en) * 2004-03-31 2005-10-20 Lintec Corp Agent for peroral administration
US7579019B2 (en) 1996-10-18 2009-08-25 Arius Two, Inc. Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
US9597288B2 (en) 2006-07-21 2017-03-21 Biodelivery Sciences International, Inc. Transmucosal delivery devices with enhanced uptake
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
JP2019122702A (en) * 2018-01-19 2019-07-25 東洋化学株式会社 Oral cavity mucosa protective film

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5511841A (en) * 1978-07-10 1980-01-28 Kanegafuchi Chemical Ind Foamed piece of plural layers and method of making said piece
JPS581423U (en) * 1982-03-19 1983-01-07 ライオン株式会社 body cavity band
JPS5879916A (en) * 1981-10-20 1983-05-13 サンド・アクチエンゲゼルシヤフト Effect continuous medicinal composition
JPS62178513A (en) * 1986-02-01 1987-08-05 Teikoku Seiyaku Kk Sheet path in oral cavity

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5511841A (en) * 1978-07-10 1980-01-28 Kanegafuchi Chemical Ind Foamed piece of plural layers and method of making said piece
JPS5879916A (en) * 1981-10-20 1983-05-13 サンド・アクチエンゲゼルシヤフト Effect continuous medicinal composition
JPS581423U (en) * 1982-03-19 1983-01-07 ライオン株式会社 body cavity band
JPS62178513A (en) * 1986-02-01 1987-08-05 Teikoku Seiyaku Kk Sheet path in oral cavity

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03209326A (en) * 1990-01-11 1991-09-12 Teikoku Seiyaku Kk Nicotine-containing cataplasm for oral cavity membrane
US7579019B2 (en) 1996-10-18 2009-08-25 Arius Two, Inc. Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
JP2002512950A (en) * 1998-04-29 2002-05-08 バイロテックス コーポレイション Drug carrier device suitable for delivering drug compounds to mucosal surfaces
JP2005325140A (en) * 1998-04-29 2005-11-24 Virotex Corp Pharmaceutical carrier device suitable for delivery of pharmaceutical compound to mucosal surface
JP2005504763A (en) * 2001-08-16 2005-02-17 アクセス ファーマシューティカルズ， インコーポレイテッド Mucoadhesive corrosive drug delivery device for controlled administration of pharmaceuticals and other active compounds
JP2005289867A (en) * 2004-03-31 2005-10-20 Lintec Corp Agent for peroral administration
US9597288B2 (en) 2006-07-21 2017-03-21 Biodelivery Sciences International, Inc. Transmucosal delivery devices with enhanced uptake
US9655843B2 (en) 2006-07-21 2017-05-23 Biodelivery Sciences International, Inc. Transmucosal delivery devices with enhanced uptake
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
JP2019122702A (en) * 2018-01-19 2019-07-25 東洋化学株式会社 Oral cavity mucosa protective film

Also Published As

Publication number Publication date
JP2635336B2 (en) 1997-07-30

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Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees