JPS6483091A - Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virus - Google Patents
Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virusInfo
- Publication number
- JPS6483091A JPS6483091A JP23897287A JP23897287A JPS6483091A JP S6483091 A JPS6483091 A JP S6483091A JP 23897287 A JP23897287 A JP 23897287A JP 23897287 A JP23897287 A JP 23897287A JP S6483091 A JPS6483091 A JP S6483091A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- reverse transcriptase
- immunodeficiency virus
- human immunodeficiency
- anthracycline derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formula I [R<1> and R<2> are H, (substituted) 1-18C alkyl, aralkyl or aryl; R<1> and R<2> may together form 1-6C alkylene, alkylidene or cycloalkylidene] and its acid addition salt. USE:Agent for inhibiting the activity of reverse transcriptase of human immunodeficiency virus. PREPARATION:14-Bromodaunomycin hydrobromide or 14-chlorodaunomycin HCl salt is made to react with a metal salt (e.g. Na salt or K salt) of a benzoic acid derivative of formula II in an organic solvent at normal temperature or under heating and, as necessary, subjecting the reaction product to chromoatographic treatment.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23897287A JPS6483091A (en) | 1987-09-25 | 1987-09-25 | Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virus |
DE88115741T DE3886155T2 (en) | 1987-09-25 | 1988-09-23 | Anthracycline derivatives with inhibitory activity against the reverse transcriptase of the human immunodeficiency virus. |
US07/248,417 US5003055A (en) | 1987-09-25 | 1988-09-23 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus |
EP88115741A EP0308977B1 (en) | 1987-09-25 | 1988-09-23 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23897287A JPS6483091A (en) | 1987-09-25 | 1987-09-25 | Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virus |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6483091A true JPS6483091A (en) | 1989-03-28 |
Family
ID=17038030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP23897287A Pending JPS6483091A (en) | 1987-09-25 | 1987-09-25 | Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virus |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6483091A (en) |
-
1987
- 1987-09-25 JP JP23897287A patent/JPS6483091A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0379979T3 (en) | ||
IE791565L (en) | Crop cutting apparatus | |
NO174711C (en) | Analogous Process for the Preparation of New Therapeutically Active Pyrimidinedione Derivatives | |
ES2071725T3 (en) | DIESTER ASCORBIC ACID AND TOCOPHERIL PHOSPHATE FOR THE INHIBITION OF THE MAILLARD REACTION. | |
GR3018387T3 (en) | Fluorinated bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them. | |
DE3267039D1 (en) | Stable s-adenosylmethionine salts, the process for their preparation and therapeutic compositions which contain them as active principle | |
HUT45230A (en) | Process for producing new phenoxy-acetic acid derivatives and pharmaceuticals comprising such compounds | |
IE891199L (en) | 2-alkyl-3-benzoylbenzofurans and pharmaceutical compositions¹containing them | |
EP0342587A3 (en) | Thienotriazolodiazepine compounds and pharmaceutical uses thereof | |
JPS55118488A (en) | Theobromine derivative and its preparation | |
JPS6483091A (en) | Anthracycline derivative active to inhibit reverse transcriptase of human immunodeficiency virus | |
HU903092D0 (en) | Process for the preparation of buten-carboxylic acid derivatives and pharmaceutical compositions containing such compounds | |
CA2038025A1 (en) | Optically active alkylenedioxybenzene derivatives and their use in therapy | |
JPS5673046A (en) | Decaprenylamine derivative | |
JPS5716855A (en) | 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation | |
EP0294069A3 (en) | Purine compounds, process for their preparation, intermediates and pharmaceutical compositions | |
GB8608893D0 (en) | D-nor-7-ergoline derivatives | |
JPS6466138A (en) | (6)-gingerol derivative | |
JPS55111447A (en) | Novel 3-amino-4-homoisotwistane derivative | |
JPS5687590A (en) | Diphosphoglycerine derivative | |
KR900016130A (en) | 2-pyridylmethylthio derivatives and ulcer treatments | |
SU1621449A1 (en) | 4-thioureidoiminomethyl pyridine perchlorate having tuberculostatic activity | |
JPS54154729A (en) | Aminobenzoic acid derivative and drug preparation containing the same | |
MY100946A (en) | New 2-(2-thienyl)-imidazo(4,5-c) pyridine derivatives and salts thereof, processes for their preparation and pharmaceutical products containing these. | |
TH2896A (en) | Pyridachinamine preparation process that is agile against virus |