JPS6479154A - Benzoylurea compound - Google Patents

Benzoylurea compound

Info

Publication number
JPS6479154A
JPS6479154A JP22442887A JP22442887A JPS6479154A JP S6479154 A JPS6479154 A JP S6479154A JP 22442887 A JP22442887 A JP 22442887A JP 22442887 A JP22442887 A JP 22442887A JP S6479154 A JPS6479154 A JP S6479154A
Authority
JP
Japan
Prior art keywords
halogen
nitro
trifluoromethyl
compound
fine particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP22442887A
Other languages
Japanese (ja)
Inventor
Nobuo Kondo
Masahiro Kikuchi
Tsunetaka Nakajima
Masahiro Watanabe
Kazumasa Yokoyama
Takahiro Haga
Shuitsu Yamada
Hideo Sugi
Toru Koyanagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ishihara Sangyo Kaisha Ltd
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Ishihara Sangyo Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Ishihara Sangyo Kaisha Ltd filed Critical Green Cross Corp Japan
Priority to JP22442887A priority Critical patent/JPS6479154A/en
Publication of JPS6479154A publication Critical patent/JPS6479154A/en
Pending legal-status Critical Current

Links

Landscapes

  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE:To provide a medicinal drug having the form of fine particles with an average particle diameter falling within a specific range, composed of a benzoylurea compound, having excellent carcinostatic activity, high absorbability through digestive tracts and good particle stability in liquid state and administrable without pain and said action of the patient. CONSTITUTION:At least one kind of benzoylurea compound selected from the compound of formula I (X is halogen, nitro or trifluoromethyl; Y is H, halogen, nitro or trifluoromethyl; when Y is nitro, X is halogen or nitro; Z1 is halogen or trifluoromethyl; Z2 is H or halogen; A is =CH- or N) and the compound of formula II (X1 and X2 are H, halogen or nitro; Y is H, halogen, nitro or trifluoromethyl; when Y is nitro, X is H; Z is H, halogen or trifluoromethyl) is crushed in a solution added with a dispersing agent and is used in the form of fine particles having an average particle diameter of <=1mum, especially 0.3-0.8mum.
JP22442887A 1986-09-29 1987-09-07 Benzoylurea compound Pending JPS6479154A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP22442887A JPS6479154A (en) 1986-09-29 1987-09-07 Benzoylurea compound

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP23052086 1986-09-29
JP22442887A JPS6479154A (en) 1986-09-29 1987-09-07 Benzoylurea compound

Publications (1)

Publication Number Publication Date
JPS6479154A true JPS6479154A (en) 1989-03-24

Family

ID=26526052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP22442887A Pending JPS6479154A (en) 1986-09-29 1987-09-07 Benzoylurea compound

Country Status (1)

Country Link
JP (1) JPS6479154A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008231119A (en) * 1992-07-01 2008-10-02 Elan Pharma Internatl Ltd Nano-particle composition

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5615272A (en) * 1979-07-17 1981-02-14 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-phenylurea compound, its preparation, and insecticide containing the same
JPS5799569A (en) * 1980-12-12 1982-06-21 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyridyloxyphenylurea type compound and insecticide comprising it
JPS57109721A (en) * 1980-12-27 1982-07-08 Ishihara Sangyo Kaisha Ltd Carcinostatic agent
JPS57144259A (en) * 1981-03-04 1982-09-06 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyridyloxyphenylurea compound and insecticide containing the same
JPS611670A (en) * 1984-06-15 1986-01-07 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyrimidinylurea and anticancer containing the same
JPS6133176A (en) * 1984-07-24 1986-02-17 Ishihara Sangyo Kaisha Ltd N-nitrobenzoyl-n'-pyridazinyloxyphenylurea compound, its preparation and carcinostatic agent containing said compound
JPS6193163A (en) * 1984-10-12 1986-05-12 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-phenylurea compound, its preparation and carcinostatic agent containing same
JPS6350346A (en) * 1986-08-15 1988-03-03 Sumitomo Electric Ind Ltd Method and device for coating optical fiber
JPH0578547A (en) * 1991-09-24 1993-03-30 Asahi Chem Ind Co Ltd High-impact styrene resin composition excellent in flame retardancy

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5615272A (en) * 1979-07-17 1981-02-14 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-phenylurea compound, its preparation, and insecticide containing the same
JPS5799569A (en) * 1980-12-12 1982-06-21 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyridyloxyphenylurea type compound and insecticide comprising it
JPS57109721A (en) * 1980-12-27 1982-07-08 Ishihara Sangyo Kaisha Ltd Carcinostatic agent
JPS57144259A (en) * 1981-03-04 1982-09-06 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyridyloxyphenylurea compound and insecticide containing the same
JPS611670A (en) * 1984-06-15 1986-01-07 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-pyrimidinylurea and anticancer containing the same
JPS6133176A (en) * 1984-07-24 1986-02-17 Ishihara Sangyo Kaisha Ltd N-nitrobenzoyl-n'-pyridazinyloxyphenylurea compound, its preparation and carcinostatic agent containing said compound
JPS6193163A (en) * 1984-10-12 1986-05-12 Ishihara Sangyo Kaisha Ltd N-benzoyl-n'-phenylurea compound, its preparation and carcinostatic agent containing same
JPS6350346A (en) * 1986-08-15 1988-03-03 Sumitomo Electric Ind Ltd Method and device for coating optical fiber
JPH0578547A (en) * 1991-09-24 1993-03-30 Asahi Chem Ind Co Ltd High-impact styrene resin composition excellent in flame retardancy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008231119A (en) * 1992-07-01 2008-10-02 Elan Pharma Internatl Ltd Nano-particle composition

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