JPS646287A - Novel platinum complex, its production and remedy for malignant tumor - Google Patents
Novel platinum complex, its production and remedy for malignant tumorInfo
- Publication number
- JPS646287A JPS646287A JP62258316A JP25831687A JPS646287A JP S646287 A JPS646287 A JP S646287A JP 62258316 A JP62258316 A JP 62258316A JP 25831687 A JP25831687 A JP 25831687A JP S646287 A JPS646287 A JP S646287A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- remedy
- malignant tumor
- trans
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The compound of formula I {R<1> is 1-18C alkyl, 1-18C alkenyl or -(X)-R<5> [X is -CH=CH- or 1-5C alkylene; R<5> is (hydroxy)phenyl, 8-13C alkoxycarbonylphenyl, etc.]; R<2> is 1-18C alkyl; R<3> is H or R<2> and R<3> together form 2-7C alkylene; R<4> is OH or NO3; the dotted line is single bond or double bond; the broken line is conjugated system; n is 1-2; the steric configuration of 1,2-diaminocyclohexane is cis, trans-l- or trans-d-}. EXAMPLE:[Pt(trans-l-1,2-diaminocyclohexane)](3-acetyl-6-methyltetrahyd ropyran- 2,4-dione)(OH.H2O) of formula II. USE:A remedy for malignant tumor. PREPARATION:A compound of formula III or formula IV is made to react with a compound of formula V in the presence of an alkali or alkaline earth metal hydroxide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62258316A JPS646287A (en) | 1986-10-15 | 1987-10-15 | Novel platinum complex, its production and remedy for malignant tumor |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24317886 | 1986-10-15 | ||
| JP62258316A JPS646287A (en) | 1986-10-15 | 1987-10-15 | Novel platinum complex, its production and remedy for malignant tumor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS646287A true JPS646287A (en) | 1989-01-10 |
Family
ID=26536135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62258316A Pending JPS646287A (en) | 1986-10-15 | 1987-10-15 | Novel platinum complex, its production and remedy for malignant tumor |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS646287A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991009041A1 (en) * | 1989-12-12 | 1991-06-27 | Toray Industries, Inc. | Novel platinum (ii) complex and drug for treating malignant tumor |
| WO1997035565A1 (en) * | 1996-03-27 | 1997-10-02 | Toray Industries, Inc. | Ketone derivatives and medicinal use thereof |
| JP2018536004A (en) * | 2015-12-02 | 2018-12-06 | ウルツファルマ・アクチェボラグ | Compounds and methods for treating bacterial infections |
-
1987
- 1987-10-15 JP JP62258316A patent/JPS646287A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991009041A1 (en) * | 1989-12-12 | 1991-06-27 | Toray Industries, Inc. | Novel platinum (ii) complex and drug for treating malignant tumor |
| US5302587A (en) * | 1989-12-12 | 1994-04-12 | Toray Industries, Inc. | Platinum (II) complex and agent for treating malignant tumor |
| WO1997035565A1 (en) * | 1996-03-27 | 1997-10-02 | Toray Industries, Inc. | Ketone derivatives and medicinal use thereof |
| JP2018536004A (en) * | 2015-12-02 | 2018-12-06 | ウルツファルマ・アクチェボラグ | Compounds and methods for treating bacterial infections |
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