JPS6461458A - Muramic acid derivative - Google Patents

Muramic acid derivative

Info

Publication number
JPS6461458A
JPS6461458A JP21581187A JP21581187A JPS6461458A JP S6461458 A JPS6461458 A JP S6461458A JP 21581187 A JP21581187 A JP 21581187A JP 21581187 A JP21581187 A JP 21581187A JP S6461458 A JPS6461458 A JP S6461458A
Authority
JP
Japan
Prior art keywords
formula
compound shown
acid derivative
muramic acid
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP21581187A
Other languages
Japanese (ja)
Inventor
Akira Hasegawa
Makoto Kiso
Yoshiaki Yoshikuni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP21581187A priority Critical patent/JPS6461458A/en
Publication of JPS6461458A publication Critical patent/JPS6461458A/en
Pending legal-status Critical Current

Links

Landscapes

  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by formula I (R<1> is H, alkyl or alkoxycarbonyl; R<2> is N3 or acyl-substituted amino; R<3> is H; R<4> is OH or acyloxy; R<3> and R<4> are bonded to form a ring; X is L-alanine, L-valine or L- serine; Y is OH or alkyloxy). EXAMPLE:N-[2-0-Azido-4, 6-0-benzylidene-N-tert-butoxycarbonyl-1,5-imino-1, 2, 5-trideoxy-D-glucitol-3-yl)-D-lactoyl]-L-alanyl-D-isoglutamine methyl ester. USE:A drug having adjuvant activity, antitumor activity and antimicrobial activ ity. PREPARATION:A compound shown by formula II and a peptide ester shown by formula III are subjected to peptide synthesis reaction (e.g. active esterification method) by a conventional procedure to give a compound shown by formula I.
JP21581187A 1987-08-28 1987-08-28 Muramic acid derivative Pending JPS6461458A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP21581187A JPS6461458A (en) 1987-08-28 1987-08-28 Muramic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21581187A JPS6461458A (en) 1987-08-28 1987-08-28 Muramic acid derivative

Publications (1)

Publication Number Publication Date
JPS6461458A true JPS6461458A (en) 1989-03-08

Family

ID=16678650

Family Applications (1)

Application Number Title Priority Date Filing Date
JP21581187A Pending JPS6461458A (en) 1987-08-28 1987-08-28 Muramic acid derivative

Country Status (1)

Country Link
JP (1) JPS6461458A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5206251A (en) * 1992-04-01 1993-04-27 G. D. Searle & Co. 2- and 3- amino and azido derivatives of 1,5-iminosugars

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