JPS6461417A - Vitamin e-containing powder having high dispersibility in water - Google Patents

Vitamin e-containing powder having high dispersibility in water

Info

Publication number
JPS6461417A
JPS6461417A JP21673687A JP21673687A JPS6461417A JP S6461417 A JPS6461417 A JP S6461417A JP 21673687 A JP21673687 A JP 21673687A JP 21673687 A JP21673687 A JP 21673687A JP S6461417 A JPS6461417 A JP S6461417A
Authority
JP
Japan
Prior art keywords
vitamin
water
spray
drying
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP21673687A
Other languages
Japanese (ja)
Other versions
JP2506812B2 (en
Inventor
Yoshiaki Kawashima
Tetsuo Handa
Hirofumi Takeuchi
Hideto Sasaki
Yasuo Miyake
Masanori Kayano
Keizo Uesugi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Priority to JP21673687A priority Critical patent/JP2506812B2/en
Publication of JPS6461417A publication Critical patent/JPS6461417A/en
Application granted granted Critical
Publication of JP2506812B2 publication Critical patent/JP2506812B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE:To obtain the titled powder having high fluidity and excellent dispersibility in water and containing vitamin E in high concentration, by using an emulsion of vitamin E which is an oily drug effective to habitual abortion, amyotrophy, cardiopathy, etc., and spray-drying the emulsion together with several specific kinds of additives. CONSTITUTION:The objective powder is produced by spray-drying a mixture of (A) vitamin E, (B) hydroxypropyl cellulose having low substitution degree or crystalline cellulose.carboxymethylcellulose sodium salt, (C) a pluronic or Tween-type surfactant and (D) silicic anhydride. The amounts of the hydroxypropyl cellulose having low substitution degree, the surfactant of the component C and the component D are preferably 0.6-1.2pts.wt., 0.05-1pt.wt. and 0.1-0.4pt.wt. per 1pt.wt. of vitamin E, respectively. Vitamin E exists in vegetable oils and fats such as wheat embryo oil and cottonseed oil.
JP21673687A 1987-08-31 1987-08-31 Vitamin E-containing powder with good water dispersibility Expired - Fee Related JP2506812B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP21673687A JP2506812B2 (en) 1987-08-31 1987-08-31 Vitamin E-containing powder with good water dispersibility

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21673687A JP2506812B2 (en) 1987-08-31 1987-08-31 Vitamin E-containing powder with good water dispersibility

Publications (2)

Publication Number Publication Date
JPS6461417A true JPS6461417A (en) 1989-03-08
JP2506812B2 JP2506812B2 (en) 1996-06-12

Family

ID=16693124

Family Applications (1)

Application Number Title Priority Date Filing Date
JP21673687A Expired - Fee Related JP2506812B2 (en) 1987-08-31 1987-08-31 Vitamin E-containing powder with good water dispersibility

Country Status (1)

Country Link
JP (1) JP2506812B2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0389982A2 (en) * 1989-03-27 1990-10-03 Lederle (Japan) Ltd. Anti-peptic ulcer agent
WO1999061000A1 (en) * 1998-05-26 1999-12-02 Eisai Co., Ltd. Powder containing fat-soluble drug
WO2000027393A1 (en) * 1998-11-06 2000-05-18 Fuji Chemical Industry Co., Ltd. Powders containing tocotrienols, process for producing the same and tablets prepared by compression molding the same
JP2009249377A (en) * 2008-11-06 2009-10-29 Shionogi & Co Ltd Water suspensibility-improved fine grain agent

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0389982A2 (en) * 1989-03-27 1990-10-03 Lederle (Japan) Ltd. Anti-peptic ulcer agent
JPH02300123A (en) * 1989-03-27 1990-12-12 Lederle Japan Ltd Remedy for peptic ulcer
WO1999061000A1 (en) * 1998-05-26 1999-12-02 Eisai Co., Ltd. Powder containing fat-soluble drug
EP1004296A1 (en) * 1998-05-26 2000-05-31 Eisai Co., Ltd. Powder containing fat-soluble drug
EP1004296A4 (en) * 1998-05-26 2000-11-22 Eisai Co Ltd Powder containing fat-soluble drug
EP1004296B1 (en) * 1998-05-26 2004-08-18 Eisai Co., Ltd. Powder containing fat-soluble drug
KR100765005B1 (en) * 1998-05-26 2007-10-09 에자이 가부시키가이샤 Powder Containing Fat-Soluble Drug
WO2000027393A1 (en) * 1998-11-06 2000-05-18 Fuji Chemical Industry Co., Ltd. Powders containing tocotrienols, process for producing the same and tablets prepared by compression molding the same
US6562372B1 (en) 1998-11-06 2003-05-13 Fuji Chemical Industry Co., Ltd. Tocotrienol-containing powder, a process for preparing it and a tablet comprising compressed said powder into a tablet form
JP2009249377A (en) * 2008-11-06 2009-10-29 Shionogi & Co Ltd Water suspensibility-improved fine grain agent

Also Published As

Publication number Publication date
JP2506812B2 (en) 1996-06-12

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