JPS6455192A - Production of acidic amino acid oligopeptide - Google Patents
Production of acidic amino acid oligopeptideInfo
- Publication number
- JPS6455192A JPS6455192A JP21389787A JP21389787A JPS6455192A JP S6455192 A JPS6455192 A JP S6455192A JP 21389787 A JP21389787 A JP 21389787A JP 21389787 A JP21389787 A JP 21389787A JP S6455192 A JPS6455192 A JP S6455192A
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- oligopeptide
- acidic amino
- acid ester
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE:To control molecular weight and readily and industrially obtain the titled oligopeptide in high yield, by adding a proteolytic enzyme to a solution of an L-acidic amino acid ester and polymerizing the above-mentioned amino acid ester. CONSTITUTION:(B) A proteolytic enzyme (e.g. papain or trypsin) capable of producing in oligopeptide in an amount of preferably 1-1,000muM is added to (A) a solution of an L-acidic amino acid ester (e.g. alpha,gamma-dimethyl L-glutamate), preferably in 10-100mM concentration and polymerization in carried out at, e.g. pH6-11 and 10-70 deg.C reaction temperature, to provide a reaction solution having preferably 2-5 polymerization degree. The resultant reaction solution is subjected to, e.g. centrifugation, to afford the aimed oligopeptide.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21389787A JPS6455192A (en) | 1987-08-27 | 1987-08-27 | Production of acidic amino acid oligopeptide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21389787A JPS6455192A (en) | 1987-08-27 | 1987-08-27 | Production of acidic amino acid oligopeptide |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6455192A true JPS6455192A (en) | 1989-03-02 |
Family
ID=16646824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP21389787A Pending JPS6455192A (en) | 1987-08-27 | 1987-08-27 | Production of acidic amino acid oligopeptide |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6455192A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03183495A (en) * | 1989-09-26 | 1991-08-09 | Chisso Corp | Method for enzymically synthesizing amino acid oligomer having single molecular weight |
US6221423B1 (en) | 1998-04-13 | 2001-04-24 | Protein Technologies Int'l Inc. | Short-chained peptide material |
-
1987
- 1987-08-27 JP JP21389787A patent/JPS6455192A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03183495A (en) * | 1989-09-26 | 1991-08-09 | Chisso Corp | Method for enzymically synthesizing amino acid oligomer having single molecular weight |
US6221423B1 (en) | 1998-04-13 | 2001-04-24 | Protein Technologies Int'l Inc. | Short-chained peptide material |
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