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Suntory Ltd
Original Assignee
Suntory Ltd
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Application filed by Suntory LtdfiledCriticalSuntory Ltd
Priority to JP62200610ApriorityCriticalpatent/JPS6442428A/en
Publication of JPS6442428ApublicationCriticalpatent/JPS6442428A/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PURPOSE:To obtain an antimalarial agent containing a quassinoid compound or bruceantin as an active ingredient. CONSTITUTION:An antimalarial agent containing a quassinoid compound or bruceantin expressed by formula I [R is H or formula II (X is 6-11C straight- chainlike or branched chain alkenyl which may have 8-10C straight-chainlike or branched chain alkyl hydroxy or acetoxy or phenyl which may be substituted by 1-5C alkyl)] as an active ingredient. The quassinoid compound exhibits excellent antimalarial activity in vivo systems and longevity effects.
3',5'-ditertbutyl-4'-hydroxyflavones, method for their preparation and pharmaceutical compositions with an antioxidant and antivasoconstricting activity