JPS6426532A - Novel unsaturated fatty acid derivative - Google Patents

Novel unsaturated fatty acid derivative

Info

Publication number
JPS6426532A
JPS6426532A JP18190187A JP18190187A JPS6426532A JP S6426532 A JPS6426532 A JP S6426532A JP 18190187 A JP18190187 A JP 18190187A JP 18190187 A JP18190187 A JP 18190187A JP S6426532 A JPS6426532 A JP S6426532A
Authority
JP
Japan
Prior art keywords
formula
fatty acid
unsaturated fatty
acid derivative
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP18190187A
Other languages
Japanese (ja)
Inventor
Toshio Nakamura
Hajime Kawakami
Keiichi Ono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharmaceuticals Co Ltd
Original Assignee
Sumitomo Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharmaceuticals Co Ltd filed Critical Sumitomo Pharmaceuticals Co Ltd
Priority to JP18190187A priority Critical patent/JPS6426532A/en
Publication of JPS6426532A publication Critical patent/JPS6426532A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An unsaturated fatty acid derivative expressed by formula I [Y is free or esterified carboxyl or formula II (R<a> and R<b> are H, lower alkyl, lower cycloalkyl, aralkyl, phenyl, halogen-substituted phenyl, etc.); R<1> is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, hydroxy-substituted alkyl, aminoalkyl substituted by R<c> and R<d> (R<c> and R<d> are H or lower alkyl), heterocyclic group, etc.]. EXAMPLE:(5Z,7E,9E)-4,11-Dihydroxy-octadeca-5,7,9-trienoic acid. USE:Useful as an antiallergic, anti-inflammatory, carcinostatic, antirheumatic agents, etc., having excellent leukotriene B4 antagonistic action. PREPARATION:A compound expressed by formula III is reduced and, as necessary, the ester group is amidated, etc., to afford the aimed compound expressed by formula I.
JP18190187A 1987-07-20 1987-07-20 Novel unsaturated fatty acid derivative Pending JPS6426532A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18190187A JPS6426532A (en) 1987-07-20 1987-07-20 Novel unsaturated fatty acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18190187A JPS6426532A (en) 1987-07-20 1987-07-20 Novel unsaturated fatty acid derivative

Publications (1)

Publication Number Publication Date
JPS6426532A true JPS6426532A (en) 1989-01-27

Family

ID=16108865

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18190187A Pending JPS6426532A (en) 1987-07-20 1987-07-20 Novel unsaturated fatty acid derivative

Country Status (1)

Country Link
JP (1) JPS6426532A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635266A1 (en) * 1993-05-28 1995-01-25 Suntory Limited Composition comprising an omega 9 series unsaturated fatty acid in the treatment of medical symptions caused by leucotriene B4
US5981588A (en) * 1994-08-09 1999-11-09 Suntory Limited ω9-unsaturated fatty acid compositions for preventing or alleviating medical symptoms caused by delayed allergy reactions

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0635266A1 (en) * 1993-05-28 1995-01-25 Suntory Limited Composition comprising an omega 9 series unsaturated fatty acid in the treatment of medical symptions caused by leucotriene B4
US5834512A (en) * 1993-05-28 1998-11-10 Suntory Limited Prevention and improvement of allergy caused by leucotriene B 4
US5861433A (en) * 1993-05-28 1999-01-19 Suntory Limited Prevention and improvement of inflammation caused by leucotriene B4
US5981588A (en) * 1994-08-09 1999-11-09 Suntory Limited ω9-unsaturated fatty acid compositions for preventing or alleviating medical symptoms caused by delayed allergy reactions

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