JPS6426532A - Novel unsaturated fatty acid derivative - Google Patents
Novel unsaturated fatty acid derivativeInfo
- Publication number
- JPS6426532A JPS6426532A JP18190187A JP18190187A JPS6426532A JP S6426532 A JPS6426532 A JP S6426532A JP 18190187 A JP18190187 A JP 18190187A JP 18190187 A JP18190187 A JP 18190187A JP S6426532 A JPS6426532 A JP S6426532A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- fatty acid
- unsaturated fatty
- acid derivative
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:An unsaturated fatty acid derivative expressed by formula I [Y is free or esterified carboxyl or formula II (R<a> and R<b> are H, lower alkyl, lower cycloalkyl, aralkyl, phenyl, halogen-substituted phenyl, etc.); R<1> is alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, hydroxy-substituted alkyl, aminoalkyl substituted by R<c> and R<d> (R<c> and R<d> are H or lower alkyl), heterocyclic group, etc.]. EXAMPLE:(5Z,7E,9E)-4,11-Dihydroxy-octadeca-5,7,9-trienoic acid. USE:Useful as an antiallergic, anti-inflammatory, carcinostatic, antirheumatic agents, etc., having excellent leukotriene B4 antagonistic action. PREPARATION:A compound expressed by formula III is reduced and, as necessary, the ester group is amidated, etc., to afford the aimed compound expressed by formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18190187A JPS6426532A (en) | 1987-07-20 | 1987-07-20 | Novel unsaturated fatty acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP18190187A JPS6426532A (en) | 1987-07-20 | 1987-07-20 | Novel unsaturated fatty acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6426532A true JPS6426532A (en) | 1989-01-27 |
Family
ID=16108865
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP18190187A Pending JPS6426532A (en) | 1987-07-20 | 1987-07-20 | Novel unsaturated fatty acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6426532A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0635266A1 (en) * | 1993-05-28 | 1995-01-25 | Suntory Limited | Composition comprising an omega 9 series unsaturated fatty acid in the treatment of medical symptions caused by leucotriene B4 |
US5981588A (en) * | 1994-08-09 | 1999-11-09 | Suntory Limited | ω9-unsaturated fatty acid compositions for preventing or alleviating medical symptoms caused by delayed allergy reactions |
-
1987
- 1987-07-20 JP JP18190187A patent/JPS6426532A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0635266A1 (en) * | 1993-05-28 | 1995-01-25 | Suntory Limited | Composition comprising an omega 9 series unsaturated fatty acid in the treatment of medical symptions caused by leucotriene B4 |
US5834512A (en) * | 1993-05-28 | 1998-11-10 | Suntory Limited | Prevention and improvement of allergy caused by leucotriene B 4 |
US5861433A (en) * | 1993-05-28 | 1999-01-19 | Suntory Limited | Prevention and improvement of inflammation caused by leucotriene B4 |
US5981588A (en) * | 1994-08-09 | 1999-11-09 | Suntory Limited | ω9-unsaturated fatty acid compositions for preventing or alleviating medical symptoms caused by delayed allergy reactions |
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