JPS6422858A - Fluorine-containing pyrimidine derivative and its preparation - Google Patents

Fluorine-containing pyrimidine derivative and its preparation

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Publication number
JPS6422858A
JPS6422858A JP17604987A JP17604987A JPS6422858A JP S6422858 A JPS6422858 A JP S6422858A JP 17604987 A JP17604987 A JP 17604987A JP 17604987 A JP17604987 A JP 17604987A JP S6422858 A JPS6422858 A JP S6422858A
Authority
JP
Japan
Prior art keywords
formula
fluorine
derivative
preparation
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP17604987A
Other languages
Japanese (ja)
Inventor
Takashi Ishihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP17604987A priority Critical patent/JPS6422858A/en
Publication of JPS6422858A publication Critical patent/JPS6422858A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A fluorine-containing pyrimidine derivative of formula I (R is H, alkyl, phenyl, NH2; R<1> is alkyl, cycloalkyl, phenyl; R<f> is perfluoroalkyl). EXAMPLE:5-Fluoro-4-trifluoromethyl-6-hexyl-2-methylpyrimidine. USE:Medicines of agrochemicals such as antibacterial, herbicide or physiologically active substance or an intermediate thereof. PREPARATION:The reaction between a fluorine-containing phosphate derivative of formula II (R<2> is lower alkyl) and an amidine derivative of formula III is carried out in an inert solvent to give the compound of formula I easily in high yield. The compound of formula II is readily prepared from a fluorine- containing ketone derivative of formula IV and dialkyl phosphite of formula IV.
JP17604987A 1987-07-16 1987-07-16 Fluorine-containing pyrimidine derivative and its preparation Pending JPS6422858A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP17604987A JPS6422858A (en) 1987-07-16 1987-07-16 Fluorine-containing pyrimidine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17604987A JPS6422858A (en) 1987-07-16 1987-07-16 Fluorine-containing pyrimidine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS6422858A true JPS6422858A (en) 1989-01-25

Family

ID=16006823

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17604987A Pending JPS6422858A (en) 1987-07-16 1987-07-16 Fluorine-containing pyrimidine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS6422858A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010843A1 (en) * 1999-08-05 2001-02-15 Mitsubishi Chemical Corporation 4-(substituted phenyl)-5-halopyrimidine derivatives and herbicides containing the same as the active ingredient
JP2005529184A (en) * 2002-06-13 2005-09-29 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト Process for the preparation of 4,6-dichloro-5-fluoropyrimidine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010843A1 (en) * 1999-08-05 2001-02-15 Mitsubishi Chemical Corporation 4-(substituted phenyl)-5-halopyrimidine derivatives and herbicides containing the same as the active ingredient
JP2005529184A (en) * 2002-06-13 2005-09-29 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト Process for the preparation of 4,6-dichloro-5-fluoropyrimidine

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