JPS6410992A - Novel blood platelet inhibitory substance om-4842, production and use thereof - Google Patents

Novel blood platelet inhibitory substance om-4842, production and use thereof

Info

Publication number
JPS6410992A
JPS6410992A JP62162245A JP16224587A JPS6410992A JP S6410992 A JPS6410992 A JP S6410992A JP 62162245 A JP62162245 A JP 62162245A JP 16224587 A JP16224587 A JP 16224587A JP S6410992 A JPS6410992 A JP S6410992A
Authority
JP
Japan
Prior art keywords
substance
blood platelet
platelet inhibitory
soluble
inhibitory substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP62162245A
Other languages
Japanese (ja)
Other versions
JPH0815435B2 (en
Inventor
Satoshi Omura
Akira Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Priority to JP62162245A priority Critical patent/JPH0815435B2/en
Publication of JPS6410992A publication Critical patent/JPS6410992A/en
Publication of JPH0815435B2 publication Critical patent/JPH0815435B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

NEW MATERIAL:A blood platelet inhibitory substance OM-4842A having 714mol. wt., molecular formula C37H46O14 and the following physical and chemical properties. Specific rotatory power: [alpha]+60. Ultraviolet absorption spectrum: lambdamax 220, 321.5 and 427.5nm. Solubility in solvent: soluble in acetone, methanol, ethanol, ethyl acetate, chloroform benzene and dimethyl sulfoxide and insoluble in water and n-hexane. Distinction of basicity and acidity: weakly acidic fat- soluble quinone substance. Color of substance: orangish red. USE:Usable as a hypotensor, a remedy for thrombosis, a carcinostatic agent, etc. PREPARATION:Streptomyces sp. OM-4842 (FERM P-9427) is cultivated in a medium containing a carbon source, a nitrogen source, an inorganic salt, etc., and the aimed substance is isolated from the prepared culture mixture and purified.
JP62162245A 1987-07-01 1987-07-01 OM-4842A, a novel platelet aggregation inhibitor, its production method and its use Expired - Lifetime JPH0815435B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62162245A JPH0815435B2 (en) 1987-07-01 1987-07-01 OM-4842A, a novel platelet aggregation inhibitor, its production method and its use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62162245A JPH0815435B2 (en) 1987-07-01 1987-07-01 OM-4842A, a novel platelet aggregation inhibitor, its production method and its use

Publications (2)

Publication Number Publication Date
JPS6410992A true JPS6410992A (en) 1989-01-13
JPH0815435B2 JPH0815435B2 (en) 1996-02-21

Family

ID=15750752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62162245A Expired - Lifetime JPH0815435B2 (en) 1987-07-01 1987-07-01 OM-4842A, a novel platelet aggregation inhibitor, its production method and its use

Country Status (1)

Country Link
JP (1) JPH0815435B2 (en)

Also Published As

Publication number Publication date
JPH0815435B2 (en) 1996-02-21

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