JPS6375667A - Flow-through type analyser - Google Patents
Flow-through type analyserInfo
- Publication number
- JPS6375667A JPS6375667A JP22148786A JP22148786A JPS6375667A JP S6375667 A JPS6375667 A JP S6375667A JP 22148786 A JP22148786 A JP 22148786A JP 22148786 A JP22148786 A JP 22148786A JP S6375667 A JPS6375667 A JP S6375667A
- Authority
- JP
- Japan
- Prior art keywords
- suction nozzle
- specimen
- standard
- ion
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 claims abstract description 31
- 239000012086 standard solution Substances 0.000 claims description 25
- 150000002500 ions Chemical class 0.000 abstract description 17
- 238000005070 sampling Methods 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 2
- 239000000523 sample Substances 0.000 description 30
- 239000003792 electrolyte Substances 0.000 description 10
- 238000005259 measurement Methods 0.000 description 7
- 238000003780 insertion Methods 0.000 description 4
- 230000037431 insertion Effects 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 3
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 description 3
- 238000012856 packing Methods 0.000 description 3
- 229910001414 potassium ion Inorganic materials 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 229910001415 sodium ion Inorganic materials 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 229910001424 calcium ion Inorganic materials 0.000 description 2
- 230000008602 contraction Effects 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 210000002381 plasma Anatomy 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 229920002379 silicone rubber Polymers 0.000 description 2
- 239000004945 silicone rubber Substances 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- GTKRFUAGOKINCA-UHFFFAOYSA-M chlorosilver;silver Chemical compound [Ag].[Ag]Cl GTKRFUAGOKINCA-UHFFFAOYSA-M 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 150000003983 crown ethers Chemical class 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
【発明の詳細な説明】
（イ）産業上の利用分野
本発明は、フロースルー方式の分析装置に関し、特に、
フロースルー方式の電解質濃度測定装置に関する。フロ
ースルー方式の電解質濃度測定装置、例えば、フロース
ルー方式のイオンメータは、血液、血漿、血清、尿、そ
の他体液及び分泌ｅ、等の検体分析等に広く使用されて
いる４本発明は、また、フロースルー方式の自動電解質
濃度測定装置の電位差測定セルの検体吸引部の改良に関
する。DETAILED DESCRIPTION OF THE INVENTION (A) Field of Industrial Application The present invention relates to a flow-through type analyzer, in particular:
This invention relates to a flow-through type electrolyte concentration measuring device. Flow-through electrolyte concentration measuring devices, such as flow-through ion meters, are widely used for analyzing samples such as blood, plasma, serum, urine, other body fluids, and secretions. , relates to improvements in the sample suction section of a potentiometric measurement cell of a flow-through type automatic electrolyte concentration measurement device.
（ロ）従来の技術
フロースルー方式の電解質濃度測定装置の電位差測定セ
ルには、試料、例えば検体が通過する流路が設けられて
おり、この流路に、夫々、イオン電極のイオン選択性Ｓ
部を露出させて、例えば、ナトリウムイオン電極、カリ
ウムイオン電極、塩素イオン電極、カルシウムイオン電
極等のイオン電極が設けられると共に、比較電極を備え
る比較電極室が設けられている。(b) Conventional technology The potentiometric measurement cell of a flow-through type electrolyte concentration measuring device is provided with a flow path through which a sample, for example, an analyte passes.
An ion electrode such as a sodium ion electrode, a potassium ion electrode, a chloride ion electrode, a calcium ion electrode, etc. is provided with the portion exposed, and a comparison electrode chamber including a comparison electrode is provided.
イオン電極としては、種々のものが提供され、実用化さ
れているが、一般に、主として使用されているものとし
ては、例えば、ナトリウムイオン電極では〃ラス膜電極
であり、カリウムイオン電極では、パリノマイシン液膜
電極或はクラウンエーテル液ＭＧｌ極であり、塩素電極
としては、銀−塩化銀の固体膜電極であり、カルシツム
電極としては、イオン交換体として有磯リン酸カルシウ
ムを用いた液体膜？ｉ！極が使用されている。Various types of ion electrodes have been provided and put into practical use, but in general, the main ones used are, for example, lath membrane electrodes for sodium ion electrodes, and palinomycin liquid electrodes for potassium ion electrodes. The membrane electrode is a crown ether liquid MGl electrode, the chlorine electrode is a silver-silver chloride solid membrane electrode, and the calcium electrode is a liquid membrane using Aiso calcium phosphate as an ion exchanger. i! poles are used.
このようなフロースル一方式の電解質濃度測定装置によ
り、試料、例えば検体中の電解質濃度の測定は、検体を
、電位差測定セルのイオン電極、例えば塩素イオン電極
カリウムイオン電極、ナトリウムイオン電極、カルシウ
ムイオン電極等に順次送ると共に、比較電極内部液を比
較電極室に送り、夫々の電極毎に電位差を測定して行わ
れる。With such a flow-through type electrolyte concentration measuring device, the electrolyte concentration in a sample, for example, a specimen, can be measured by transferring the specimen to an ion electrode of a potentiometric measurement cell, such as a chloride ion electrode, a potassium ion electrode, a sodium ion electrode, a calcium ion electrode. At the same time, the internal solution of the comparison electrode is sent to the comparison electrode chamber, and the potential difference is measured for each electrode.
しかし、イオン電極の感度は、周囲温度の変化及び振動
により変化するために、長時間に亘り一定した感度に保
つことは難しい。また、フロースルー方式の？ｌｉ解′
ｒ１漬度測定装置では、全血、血漿又は血清を希釈しな
いで、その侭測定に供する場合があり、この場合は、イ
オン電極面に、検体中の脂質や蛋白質が付着し易く、感
度の低下をきたし易い。However, since the sensitivity of the ion electrode changes due to changes in ambient temperature and vibrations, it is difficult to maintain a constant sensitivity over a long period of time. Also, is it a flow-through method? li solution′
With the r1 soakage measurement device, whole blood, plasma, or serum may be used for undiluted measurements. In this case, lipids and proteins in the sample tend to adhere to the ion electrode surface, resulting in a decrease in sensitivity. It is easy to cause
そこで、フロースルー方式の電解質濃度測定装置におい
ては、電解質濃度の測定を安定して行うために、検体と
標準液を交互に測定している。Therefore, in the flow-through type electrolyte concentration measuring device, in order to stably measure the electrolyte concentration, the sample and the standard solution are measured alternately.
（ハ）発明が解決しようとする問題点
このように、試料、例えば検体と標準液とを交互に、イ
オン１を極及び比較電極室を備えるフロースルー方式の
電位差測定セルに送り測定するには、吸引ノズル、例え
ばサンプルプローブ或はサンプリングノズルにより、検
体と標準液を交互に吸引する必要がある。(c) Problems to be Solved by the Invention In this way, in order to alternately send and measure a sample, for example, a specimen and a standard solution, ion 1 is sent to a flow-through type potentiometric measurement cell equipped with an electrode and a reference electrode chamber. , it is necessary to alternately aspirate the specimen and the standard solution using a suction nozzle, such as a sample probe or a sampling nozzle.
そこで、従来のフロースルー方式の電解質濃度測定装置
においては、検体と標準液を交互に吸引するための吸引
切換え機構として、例えば、内部中空部が標準液供給源
に連通する標準液槽を、検体容器のサンプリング位置の
上方に配設している。Therefore, in conventional flow-through type electrolyte concentration measuring devices, the suction switching mechanism for alternately aspirating the specimen and standard solution is, for example, a standard solution tank whose internal hollow part communicates with the standard solution supply source. It is placed above the sampling position of the container.
この場合、サンプリングノズルは、Ｉｉ汀汀線標準液槽
中空部に挿通されており、サンプリングノズルの上下移
動動作によって、前記中空部と検体容器の間を、上下方
向に往復動して、検体と標準液とを交互に吸引する。こ
の場合、標準液槽底部は、吸引ノズル挿通用のスリット
を有するシリコンゴム等のセプタムで形成されており、
サンプリングノズルによる標準液の吸引の際には、吸引
ノズル先端を標準液槽内に引き込ませるために、セプタ
ムの劣化により、スリット部から液洩れを生じ問題とさ
れている８
しかも、このように吸引切換え機構は、材質上からも＋
！！１構−りからも耐久性に乏しく、長期間の使用に適
するものでないために、例えばシリコンゴム製のセプタ
ムの場合には、概略−千検体を吸引したところで、新し
いセプタムと取替えている。In this case, the sampling nozzle is inserted into the hollow part of the Ii shoreline standard liquid tank, and by the vertical movement of the sampling nozzle, it reciprocates in the vertical direction between the hollow part and the sample container, and the sample and standard Aspirate the liquid alternately. In this case, the bottom of the standard liquid tank is formed of a septum made of silicone rubber or the like with a slit for inserting the suction nozzle.
When aspirating the standard solution using the sampling nozzle, the tip of the suction nozzle is drawn into the standard solution tank, which causes problems such as leakage from the slit due to deterioration of the septum8. The switching mechanism has +
! ! For example, in the case of a silicone rubber septum, it is replaced with a new one after approximately 1,000 samples have been aspirated, since it has poor durability and is not suitable for long-term use.
このような吸引切換え機構の取替えは、電解質濃度測定
装置の作動を中断するために、検体処理を遅らせる結果
となり問題である。Replacing such a suction switching mechanism is problematic because it interrupts operation of the electrolyte concentration measuring device, resulting in delayed sample processing.
本発明は、従来の吸引切換え磯溝の耐久性にもとづく問
題、αを解決することを目的としている。The present invention aims to solve the problem α based on the durability of the conventional suction switching rock groove.
（ニ）問題点を解決するための手段
本発明は、サンプリングノズルによる検体と標ｇｉ液と
の交互の吸引を長時間に亘って正確でかつ安定して行う
ことがでさる切換え吸引採取８′１構を提供するもので
ある。(d) Means for Solving the Problems The present invention provides a switching suction sampling system 8' that allows alternate suction of a sample and a standard GI liquid through a sampling nozzle accurately and stably over a long period of time. It provides one structure.
すなわち、本発明は、底部の少くとも一部か弾性部材で
形成されて標準液を収容するＩ２へｆ１液槽内に、測定
装置に一端が連通する吸引ノズルが往復動可能に挿通さ
れていて、吸引ノズルを往復動させることにより、検体
と標準液を交互に該ノズル開口から吸引し、測定するフ
ロースルー方式分析装置において、吸引ノズルが、一端
が閉鎖されると共に該閉鎖端に近接する側壁部に開口を
有する中空管状体で形成されていることを特徴とするフ
ロースルー方式分析装置にある。That is, in the present invention, a suction nozzle, one end of which communicates with the measuring device, is reciprocatably inserted into the liquid tank I2 and f1, the bottom of which is formed of an elastic member at least in part and which accommodates the standard liquid. , a flow-through analyzer in which a sample and a standard solution are alternately aspirated and measured from a nozzle opening by reciprocating a suction nozzle, the suction nozzle has one end closed and a side wall adjacent to the closed end. A flow-through type analyzer is characterized in that it is formed of a hollow tubular body having an opening at the bottom.
本発明において、吸引ノズルは、一端が閉鎖され、側壁
部に開口をする中空管状体に形成される。In the present invention, the suction nozzle is formed into a hollow tubular body with one end closed and an opening in the side wall.
したがって、本発明の吸引ノズルは、側壁部の開口を通
して、検体及び標準液を吸引する。この吸引ノズルにお
いて、開口が設けられる側！！！部の箇所は、検体及び
標章液が該開口を通して吸引できる位置であり、しかも
、標準液の吸引の際には、吸引ノズルのｌｌ￥Ｉ頻端が
セプタム、パツキン等の弾性部材内に留まることができ
る位１ｎとされる。したがって、本発明の吸引ノズルに
おいて、開口は、例えば、！■頻された端部に近接させ
て設けられる。Therefore, the suction nozzle of the present invention suctions the specimen and standard solution through the opening in the side wall. In this suction nozzle, the side where the opening is provided! ! ! This is the position where the sample and marking solution can be aspirated through the opening, and when the standard solution is aspirated, the ll\I end of the suction nozzle remains within the elastic member such as the septum or gasket. It is said to be 1n as much as possible. Therefore, in the suction nozzle of the present invention, the opening is, for example! (2) Provided close to the cut end.
この場合、開口部の向きは、当然、管状体軸線に対して
略垂直方向とならざるを得ないので、デッドスペースが
無視できる大きさになるように注意する必要がある０例
えば、閉鎖端に肉盛りをして、側壁部の開口からの流路
を流線形状に形成すると、標準液槽底部の弾性部材内に
留まる長さが確保できて、デッドスペースの問題が解消
できるので好ましい、この場合、少くとも吸引ノズルの
標準液槽を通る部分の外形を同形状とすると、弾性部材
の過度の伸縮を妨げるので好ましい。In this case, the orientation of the opening must be approximately perpendicular to the axis of the tubular body, so care must be taken to ensure that the dead space is negligible. It is preferable to build up the wall and form the flow path from the opening in the side wall into a streamlined shape, as this will ensure the length to stay within the elastic member at the bottom of the standard liquid tank and solve the problem of dead space. In this case, it is preferable to make at least the outer shape of the part of the suction nozzle that passes through the standard liquid tank the same shape, since this prevents excessive expansion and contraction of the elastic member.
本発明において、標準液を収容する標準液槽は、公知の
標準液槽と同様な構造とすることができる。In the present invention, the standard solution tank containing the standard solution can have a similar structure to a known standard solution tank.
しかし、本発明においては、標準液槽底部の弾性部材は
、吸引ノズル側壁部と接して、該弾性部材と吸引ノズル
側壁部間を液が洩れない状態、即ち液密なシール状態に
保つことができれば足りるので、標準？！！槽のセプタ
ム等の弾性部材には、吸引ノズル側壁部と接触する部分
の伸縮等による疲労を極力避けるために、吸引ノズルの
外形より僅かに小さい断面形状の孔を設けるのが好まし
い。However, in the present invention, the elastic member at the bottom of the standard liquid tank is in contact with the side wall of the suction nozzle to maintain a liquid-tight seal between the elastic member and the side wall of the suction nozzle. Is it standard because it is enough if possible? ! ! It is preferable that an elastic member such as a septum of the tank is provided with a hole having a cross-sectional shape slightly smaller than the outer diameter of the suction nozzle in order to avoid fatigue caused by expansion and contraction of the portion in contact with the side wall of the suction nozzle as much as possible.
（ホ）作用
本発明、吸引ノズルの下端を閉鎖すると共に該ノズル側
！！！部に開口を形成したので、標阜液吸引時において
、吸引ノズル下端を標準液槽のセプタム、パツキン等の
シール部材内に留まらせて、吸引ノズル側壁部の開口が
ら吸引ノズル内に標準液の吸引を行うことができること
になり、標準Ｐ＆槽槽底リシール部材吸引／ズル挿通箇
所を、吸引ノズルにより絶えず封鎖することになって、
標ＩＰ、′？ＦＬ槽底部のシール部材の弾性低下環の劣
化による液洩れを極力避けることができる。(E) Function The present invention closes the lower end of the suction nozzle and also closes the nozzle side! ! ! Since an opening is formed in the side wall of the suction nozzle, when suctioning the standard liquid, the lower end of the suction nozzle remains within the sealing member such as the septum or packing of the standard liquid tank, and the opening on the side wall of the suction nozzle allows the standard liquid to be drawn into the suction nozzle. This means that suction can be carried out, and the suction nozzle will constantly seal off the suction/slip insertion point of the standard P & tank bottom reseal member.
Marked IP,'? Liquid leakage due to deterioration of the elasticity-decreasing ring of the sealing member at the bottom of the FL tank can be avoided as much as possible.
したがって、本発明によると、長時間使用しても、液洩
れによる不測の事態が極力避けられることになって、液
洩れによる分析積度の低下を防止することができる。Therefore, according to the present invention, even if the device is used for a long time, unexpected situations due to liquid leakage can be avoided as much as possible, and a decrease in analysis volume due to liquid leakage can be prevented.
（へ）実施例
以下、添付図面を参照して、本発明の実施の一態様につ
いて説明するが、本発明は、この説明及び例示によって
何らの制限を受けるものではない。(F) Example Hereinafter, one embodiment of the present invention will be described with reference to the accompanying drawings, but the present invention is not limited in any way by this description and exemplification.
図は、本発明のフロースルー方式の分析ＶＣ置の一実施
例における標準１ｇ、槽及び吸引ノズル部分の概略を示
す説明図である。The figure is an explanatory diagram schematically showing a standard 1g, a tank, and a suction nozzle portion in an embodiment of the flow-through type analysis VC device of the present invention.
標準液槽１は、標準液導入口２を側壁３の下部に有し、
側壁３の頂ｇ４に中央に案内孔５を有する天板６が設け
られている。天板６は台板７にねじ８，８′ を介して
固定されている。標準′ｅ、′Ｗ１１の底部９には、中
央部に挿通孔１０を有するパツキン１１が、該挿通孔１
０と略同様の案内孔１２を有する押えねじ１３により固
定されている。The standard liquid tank 1 has a standard liquid inlet 2 at the bottom of the side wall 3,
A top plate 6 having a guide hole 5 in the center is provided at the top g4 of the side wall 3. The top plate 6 is fixed to the base plate 7 via screws 8, 8'. The bottom part 9 of the standard 'e, 'W11 has a packing 11 having an insertion hole 10 in the center.
It is fixed by a retaining screw 13 having a guide hole 12 substantially similar to that of 0.
吸引ノズル１４は、ノズルホルダ（図示されていない。The suction nozzle 14 is attached to a nozzle holder (not shown).
）により保持されており、上下矢印１５方向に移動可能
であり、また、吸引ノズル１４は、は、その下端１６に
閉鎖され、下端側壁部１７に開口１８を有しており、そ
の上端（図示されていない。）は、イオンメータ１つに
接続する接続管２０に接続している。), and is movable in the direction of the up and down arrow 15, and the suction nozzle 14 is closed at its lower end 16, has an opening 18 in the lower end side wall 17, and has an opening 18 at its upper end (not shown). ) is connected to a connecting pipe 20 that connects to one ion meter.
標準液槽１の下方には、吸引ノズル１４の到達位置に、
検体ラック２１が設けられている。検体ラック２１には
検体カップ２２．２２’、２２°・・・が配設されてお
り、分析用検体が収容されている。Below the standard liquid tank 1, at the position reached by the suction nozzle 14,
A sample rack 21 is provided. Sample cups 22, 22', 22°, . . . are arranged in the sample rack 21, and contain samples for analysis.
本例においては、検体ラック２１は、矢印２３方向に、
常法により間欠的に移動させられ、その停止時に、吸引
ノズル１４により、検体採取位置２４に位置する検体容
器２２′から検体２５が吸引採取される。In this example, the sample rack 21 is arranged in the direction of the arrow 23.
It is moved intermittently by a conventional method, and when stopped, the sample 25 is sucked and collected from the sample container 22' located at the sample collection position 24 by the suction nozzle 14.
本例はこのように構成されているので、検体採取時には
、吸引ノズル１４を矢印１５方向に下降させ、検体採取
位置に停止する検体カップ２２′から検体２５を吸引採
取し、接続管２ｏを介してイオンメータ１９に送り、目
的のイオン濃度を測定する６次いで、吸引ノズル１４を
矢印１５方向に上昇させて、吸引ノズル１４の開口１８
を標準液槽内に位置させて、標準液２６を吸引ノズル１
４から吸引し、接続管２０がらイオンメータ１９に送っ
て、標準液のイオン濃度を測定して、例えば、前に測定
したイオン濃度測定値を更正する。Since this example is configured as described above, when collecting a sample, the suction nozzle 14 is lowered in the direction of the arrow 15, the sample 25 is sucked and collected from the sample cup 22' that is stopped at the sample collection position, and the sample 25 is collected via the connecting tube 2o. Then, the suction nozzle 14 is raised in the direction of arrow 15, and the opening 18 of the suction nozzle 14 is measured.
is placed in the standard solution tank, and the standard solution 26 is sucked into the suction nozzle 1.
4 and sends it to the ion meter 19 through the connecting tube 20 to measure the ion concentration of the standard solution, for example, to correct the previously measured ion concentration value.
本例においては、図にも示されるように、標準液Ｍｇ１
の底部パツキン１１の挿通孔１０には、標準液の採取の
如何に係らず、吸引ノズル１４が挿通されているので、
パツキン１１が破損されない限り、液洩れを起すことが
ない。In this example, as shown in the figure, the standard solution Mg1
Since the suction nozzle 14 is inserted into the insertion hole 10 of the bottom gasket 11 regardless of whether the standard solution is collected,
As long as the packing 11 is not damaged, liquid leakage will not occur.
（ト）発明の効果
本発明は、吸引ノズルを、下端を閉鎖し、下端に近接す
る側壁部に開口を有する中２管状体に形成したので、標
準に！、槽に開口を位置させて、標準液を吸引する場合
でも、吸引ノズルの閉鎖端を、標準液槽の底部の一部を
形成するセプタム、パツキン等の弾性部材即ちシール部
材内に、位ｉ？！させることができるので、従来の吸引
切換磯情に比してパツキン等の弾性部材から、吸引ノズ
ルが抜は出て生じる液洩れを起−１ことがなく、液洩れ
による分析４ｆｆの異常値の発生を避けることができる
。(g) Effects of the Invention In the present invention, the suction nozzle is formed into a double-tubular body with a closed lower end and an opening in the side wall near the lower end, making it standard! Even when the standard solution is aspirated by positioning an opening in the tank, the closed end of the suction nozzle should be positioned within an elastic member such as a septum or a sealing member that forms part of the bottom of the standard solution tank. ? ! Therefore, compared to the conventional suction switching system, there is no possibility of liquid leakage caused by the suction nozzle coming out from an elastic member such as a gasket, and the abnormal value of analysis 4ff due to liquid leakage is reduced. Occurrence can be avoided.
図は、本発明のフロースルー方式の分析装置の一実施例
における標章液槽及び吸引ノズル部分の概略を示を説明
図である。
図中の符号については、１は標準液槽、２は標準液導入
［コ、３は側壁、４は頂部、５及び１２は案内孔、６は
天板、７は台板、８，８′はねじ、９は底部、１０は挿
通孔、１１はパツキン、１３は押えねじ、１４は吸引７
：！ニル、１５及び２３は矢印、１６は吸引／７：ルの
下端、１７は下端側壁部、１８は開口、１９はイオンメ
ータ、２０は接続管、２１は検体ラック、２２．２２’
、２２’ は検体カップ、２４は検体採取位置、２５は
検体、２６は標準液である。
代 理 人The figure is an explanatory diagram schematically showing a mark liquid tank and a suction nozzle portion in an embodiment of the flow-through type analyzer of the present invention. Regarding the symbols in the figure, 1 is the standard solution tank, 2 is the standard solution introduction [ko], 3 is the side wall, 4 is the top, 5 and 12 are the guide holes, 6 is the top plate, 7 is the base plate, 8, 8' 9 is the screw, 9 is the bottom, 10 is the insertion hole, 11 is the gasket, 13 is the holding screw, 14 is the suction 7
:! 15 and 23 are arrows, 16 is the lower end of suction/7: 17 is the lower end side wall, 18 is the opening, 19 is the ion meter, 20 is the connecting tube, 21 is the sample rack, 22.22'
, 22' is a sample cup, 24 is a sample collection position, 25 is a sample, and 26 is a standard solution. agent
Claims (1)
容する標準液槽内に、測定装置に一端が連通する吸引ノ
ズルが往復動可能に挿通されていて、吸引ノズルを往復
動させることにより、検体と標準液を交互に該ノズル開
口から吸引し、測定するフロースルー方式分析装置にお
いて、吸引ノズルが、一端が閉鎖されると共に該閉鎖端
に近接する側壁部に開口を有する中空管状体で形成され
ていることを特徴とするフロースルー方式分析装置。A suction nozzle, one end of which communicates with the measuring device, is reciprocatably inserted into a standard liquid tank whose bottom part is at least partially made of an elastic member and contains a standard liquid, and the suction nozzle is reciprocated. In a flow-through analyzer that alternately aspirates and measures a specimen and a standard solution from the nozzle opening, the suction nozzle is a hollow tubular body with one end closed and an opening in the side wall near the closed end. A flow-through analyzer characterized in that it is formed of:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22148786A JPS6375667A (en) | 1986-09-19 | 1986-09-19 | Flow-through type analyser |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22148786A JPS6375667A (en) | 1986-09-19 | 1986-09-19 | Flow-through type analyser |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6375667A true JPS6375667A (en) | 1988-04-06 |
Family
ID=16767482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22148786A Pending JPS6375667A (en) | 1986-09-19 | 1986-09-19 | Flow-through type analyser |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6375667A (en) |
-
1986
- 1986-09-19 JP JP22148786A patent/JPS6375667A/en active Pending
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