JPS635022B2 - - Google Patents

Info

Publication number
JPS635022B2
JPS635022B2 JP8366280A JP6628083A JPS635022B2 JP S635022 B2 JPS635022 B2 JP S635022B2 JP 8366280 A JP8366280 A JP 8366280A JP 6628083 A JP6628083 A JP 6628083A JP S635022 B2 JPS635022 B2 JP S635022B2
Authority
JP
Japan
Prior art keywords
fraction
rocagramide
chloroform
methanol
column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP8366280A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59190956A (ja
Inventor
Meiju Kin
Kinji Kyo
Kankin Rin
Masahito Ochiai
Hidekazu Fujita
Tei Matsukufueiru Andoryuu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP58066280A priority Critical patent/JPS59190956A/ja
Priority to US06/542,140 priority patent/US4539414A/en
Publication of JPS59190956A publication Critical patent/JPS59190956A/ja
Publication of JPS635022B2 publication Critical patent/JPS635022B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
JP58066280A 1983-04-15 1983-04-14 ロカグラマイド化合物 Granted JPS59190956A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP58066280A JPS59190956A (ja) 1983-04-15 1983-04-14 ロカグラマイド化合物
US06/542,140 US4539414A (en) 1983-04-15 1983-10-14 1H-Cyclopenta[b]benzofuran derivative and its analog

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58066280A JPS59190956A (ja) 1983-04-15 1983-04-14 ロカグラマイド化合物

Publications (2)

Publication Number Publication Date
JPS59190956A JPS59190956A (ja) 1984-10-29
JPS635022B2 true JPS635022B2 (ref) 1988-02-01

Family

ID=13311255

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58066280A Granted JPS59190956A (ja) 1983-04-15 1983-04-14 ロカグラマイド化合物

Country Status (2)

Country Link
US (1) US4539414A (ref)
JP (1) JPS59190956A (ref)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7276594A (en) * 1993-08-13 1995-03-14 Banyu Pharmaceutical Co., Ltd. Endothelin-antagonistic cyclopentane derivative
DE69426698T2 (de) * 1993-08-18 2001-08-16 Banyu Pharmaceutical Co., Ltd. Kondensierte heteroaromatische cyclopentenderivate mit endothelin-antagonistischer aktivität
DE19835324A1 (de) 1998-08-05 2000-02-10 Bayer Ag Cyclopentabenzofuran-Derivate und ihre Verwendung
DE19835325A1 (de) * 1998-08-05 2000-02-10 Bayer Ag Verwendung von Cyclopentabenzofuran-Derivaten zur Bekämpfung von NF-kB abhängigen Krankheiten
EP1693059A1 (en) * 2005-02-22 2006-08-23 Deutsches Krebsforschungszentrum Use of rocaglamide derivatives as NF-AT-specific inhibitors for the treatment of certain inflammatory diseases
EP2189158A1 (en) 2008-11-20 2010-05-26 DKFZ Deutsches Krebsforschungszentrum, Stiftung des Öffentlichen Rechts Combination of rocaglamide and apoptosis inducing substances for the treatment of cancer
CN119638657B (zh) * 2023-09-18 2026-03-27 华中科技大学 一种间苯三酚化合物、分离及应用
CN117919292B (zh) * 2024-01-26 2025-02-07 广西中医药大学 一种万寿菊提取物及其在制备抗前列腺癌药物中的应用

Also Published As

Publication number Publication date
JPS59190956A (ja) 1984-10-29
US4539414A (en) 1985-09-03

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