JPS63227503A - Termite-controlling agent - Google Patents

Abstract

PURPOSE:To provide a termite-controlling agent containing 3-phenoxy-alpha- cyanobenzyl 2-(2-chloro-4-trifluoromethylphenylamino)-3-methylbutanoate and piperonyl butoxide as an adjuvant. CONSTITUTION:The objective termite-controlling agent contains (A) the compound of formula and (B) [3,4-(methylenedioxy)-6-propylbenzyl]butyl diethylene glycol ether at a ratio of 1:1-10. The compound of formula is an expensive chemical and its amount can be decreased keeping high insecticidal and moth- proofing effect by mixing with the above synergist to enable the reduction of cost. The above termite-controlling agent may be properly compounded with a termite-attractant, other insecticide, preservative, etc., to further improve the controlling effect. It can be used in the form of oil solution, emulsifiable concentrate, wettable powder, powder, aerosol, etc.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention provides 3-phenoxy-α-cyanobendiρ2-(2
-Chloro-4-trifluoromethylphenylamino)-
The present invention relates to a termite control agent characterized by containing 3-methylbutanoate (hereinafter referred to as compound A).

In recent years, damage caused by pests that damage wood, such as termites, carp beetles, and rat bark beetles, has become a problem. In order to prevent damage from these pests, the materials have traditionally been treated with an appropriate insect repellent in advance, and for this purpose, organochlorine insecticides such as chlordane and dieldrin have been used as insecticidal and insect repellent ingredients.

However, these insecticidal and insect repellent ingredients all have problems in terms of persistence, toxicity, irritation, and environmental pollution, and their use was banned last year.

As an alternative to these, organic phosphorus agents such as chlorpyrifos and phoxim have recently been overwritten, but they are easily decomposed in the soil and have many safety issues for humans and livestock, so new termite control agents with low toxicity have been developed. Development is desired.

The present inventors have spent many years researching pyrethroid drugs that are characterized by low toxicity and can be used for this type of purpose, and as a result, we have discovered a compound that is superior to chlordane and dieldrin in terms of insecticidal properties and residual efficacy. I found A.

Compound A has already been put into practical use in the field of agriculture and horticulture because it has high insecticidal activity against insect pests of the order Phosphoroptera, aphids, spider mites, etc., but it has low activity against pests of the order Orthoptera. Until now, it was thought that it was unsuitable for use as a termite control agent.

However, when considering the ecology of termites, the present inventors believe that basic insecticidal efficacy tests alone are inappropriate for evaluating and evaluating the insecticidal and insect repellent ingredients of termite control agents, and therefore, we have conducted practical tests on various pyrethroids. When a wood treatment test was conducted, it was revealed that Compound A has a high effect on preventing feeding damage.

Compound A has the advantages of rapid action against insects and low toxicity against warm-blooded animals, which are the characteristics of a pyrethroid drug, and at the same time has an extremely excellent residual effect.

The present invention is extremely useful in that it not only provides Compound A, which is most suitable as an insecticidal and repellent component of a termite control agent, but also opens up the application of pyrethroid drugs to the field of termites.

Furthermore, in view of the fact that Compound A is an expensive insecticide compared to organochlorine insecticides and organophosphorus agents, the present inventors investigated the effects of mixing Compound A and a synergist for pyrethroid in order to reduce costs. As a result of a thorough study of termites,
Various pyrethroid synergists such as cinepirin 500, octachlorodipropyl ether, MGK-264, MGK-5026, sesamin, sulfoxide, and N-A-16388 are ineffective, and the compound does not specifically target termites. A and [3,4-(methylenedioxy)-6-
The present invention was completed by discovering that only the combination of brobylbenzyl]butyl diethylene glycol ether (hereinafter referred to as piveronyl butoxide) exhibits a remarkable effect.

Previously, it was thought that various pyrethroid synergists would exhibit similar synergistic effects when combined with Compound A, even if there were slight differences, based on test results on flies, mosquitoes, etc. The phenomenon peculiar to ants is completely unexpected from conventional knowledge.

As a result, high insecticidal and insect repellent effects can be obtained even if the amount of compound A is reduced, and the practical advantages in terms of cost are immeasurable.

Compound A used in the present invention is represented by the following formula (I) and has asymmetric carbon atoms, and there are optical isomers based on this, and each of them or a mixture thereof is included.

The termite control agent contains 0.0% of Compound A as an insecticidal and insect repellent ingredient.
The mixing ratio of compound A and piveronyl butoxide is 3:1 to 1:0.
20 (preferably 1:1 to 1:1.0) is suitable.

Furthermore, a termite attractant may be appropriately added in order to more efficiently exhibit insecticidal and insect repellent effects. Historically, the termite control agent of the present invention may be used, for example, with organic phosphorus agents such as chlorbyrifos, phoxim, and pyridafentionate, pyrethroid agents such as permethrin, fenvalerate, and fenpropathrin, or other agents such as tripropylisocyanurate and carbamate agents. Insecticides, as well as various types of preservatives, such as 0CCA compounds, CCA, CCB, etc.Ohalophe'-'' compounds - pentachlorophenyllaurate, p-promo-2,6-dichlorophenol, etc. O iodopropargyl compound-F-1000゜3-
Iodo-2-propynyl butymu carbamate etc.0 Quaternary ammonium compounds and amine salts -11 Penzalkonium chloride, sia μkimu dimethylammonium chloride etc.0 Organotin compounds - bis(n-)liptyltin) oxide, tributyltin A useful multi-purpose composition can also be obtained by appropriately mixing tereph grate, etc., and others such as zinc naphthenate and xyligen aluminum lamb salt.

The formulation of the mortar ant control agent of the present invention may vary depending on the properties of the control agent and the purpose of use, such as an oil solution, an emulsion, an aqueous solution, a water solvent, a powder, and an aerosol. It is Noh. Any of the preparations can be prepared according to a conventional method, and solid carriers include fine powders or powders such as clays (kaolin, bentonites, etc.), talcs, and the like. As the liquid carrier, water, alcohols, aromatic hydrocarbons (for example, toluene, xylene, etc.), aliphatic hydrocarbons (for example, kerosene, kerosene, etc.), esters, nitriles, etc. can be used. Next, as surfactants, alkyl sulfates, alkyl sulfonates, ap-aryl sulfonates, polyethylene glyco-ethers, polyhydric
Examples include co-esters. In addition, fixing agents and dispersing agents such as casein, gelatin, starch powder, CMC, and polyvinyl alcohol are used as appropriate. Furthermore, by microencapsulating or cyclodextrin inclusion of Compound A used in the present invention, a preparation can be obtained that further increases chemical stability and enhances residual efficacy in soil. On the other hand, the same effect as above can be obtained with a mixture of Compound A and Piveroni μ-butoxide.

The termite control agent of the present invention can be applied using conventional methods, such as spraying or foaming emulsions, oils, irrigation agents, powders, etc. on the soil under and around houses, or applying or applying pressure to wood, plywood, etc. It is also possible to apply it as a termite-preventive coating by injecting it, or by impregnating it with a termite-controlling bait, colored paint, varnish, or the like.

Furthermore, the microencapsulated or cyclodextrin-encapsulated preparation has increased residual effectiveness in soil, and is an effective application method as a soil treatment agent.

EXAMPLES In order to further clarify the usefulness of the present invention, Examples and Test Examples will be described below, but it goes without saying that the present invention is not limited to these.

Example 1 0.1 part of Compound A and 8 parts of F-10000 are dissolved in fume kerosene to make the total 100 parts to obtain an oil solution.

Example 2 0.05 part of Compound A, 0.5 part of Piveroni μ-butoxide, and 0.5 part of bis-(n-tributyltin) oxide are dissolved in fume kerosene to give a total of 100 parts. The wood to be insect-proofed is dipped in this oil, or the oil is sprayed or applied on the surface.

Example 3 To 2 parts of Compound A and 10 parts of piveronyl ptoxide, 5 parts of Tsurupo/l/8M-200 (registered trademark of Toho Chemical), 20 parts of Xylo-/I/, and 63 parts of white kerosene were added. Stir well to mix and dissolve to obtain an emulsion.

This emulsion is diluted 20 times with water and the wood is immersed in the solution or applied or sprayed on the surface.

2.5 parts of this emulsion is added to 97.5 parts of a phenolic urea and melamine adhesive used for manufacturing plywood, mixed well, and used.

Example 4 25 parts of 5M-200 (same as above), 27 parts of xylo-71,723 and white kerosene were added to 5 parts of compound A, 10 parts of piveronyl ptoxide, and 1 part of pentachlorophenol/l/lO. Stir well to mix and dissolve to obtain an emulsion.

A 50-fold diluted solution of this emulsion is sprayed onto the soil under the house.

Example 5 1 part of compound A and 5 parts of piveronyl butoxide were dissolved in 125 parts of trioctyl phosphate, 50 parts of vinyl chloride raw resin, 2.5 parts of royal basic lead sulfate, and 16.
Add 5 parts and mix well to obtain a vinyl chloride compound for covering electric wires.

Test Example 1 (Wood treatment test) Based on the standards of the First Japan White Foot Control Association, 110 g/r of oil at a specified concentration of the test chemical was applied to a piece of wood (1 x 1 x 2 cm).
d, and after air drying for 2 weeks, each was used as a test piece.

Next, one piece of each of these test pieces was placed in the same nest box for termites, and the rate of weight loss due to feeding damage and the condition of the ant trail after 3 weeks were observed.

In the table, the degree of damage indicated by 0 to V is the degree of the number of ant tracks that occurred, and indicates the stage from 0) with no number of ant tracks to (V) with a significant number of ant tracks.

(Topical application contact test) Acetone solutions of various concentrations of the test drug were locally applied to the backs of house termites using a microsyringe, and the basic efficacy of the drug upon contact was determined from the mortality rate after 24 hours.

When exterminating sanitary pests such as flies, mosquitoes, and cockroaches, the most important factors are the knockdown effect and subsequent lethal effect caused by contact with or ingestion of chemicals, but exterminating termites is completely different from sanitary pest extermination.

In other words, termites live in groups by digesting cellulose with the help of symbiotic protozoa and eating each other's excreta to maintain this quality, so killing one or several termites is not effective in controlling them. No. In addition, termites use excrement and clay to create nests and ant trails, and live mainly underground, so they rarely attract attention like sanitary pests, so it is difficult to completely wipe out the entire termite nest. In other words, the ultimate role of termite control agents is to protect wood and buildings from termite damage. Therefore, although the local application contact test may serve as a guide for efficacy evaluation, it alone is meaningless; instead, a method of placing wood chips treated with the test chemical in a termite habitat and observing the feeding damage (
The wood treatment test in Test Example 1) has been established as the anti-termite effectiveness test method by the Japanese White Ant Countermeasures Association.

The test results showed that Compound A was superior to other pyrethroid agents (&2-4) and organophosphorus agent (A5;
Although the efficacy was lower than that of phoxim), it showed the highest anti-feeding effect in the wood treatment test, and was effective as a termite control agent.
Its usefulness as an insect repellent ingredient has been revealed.

(According to the standards of the First Japan White Foot Control Association, a weight loss rate of 3% or less is considered to be acceptable.) On the other hand, permethrin, another pyrethroid agent, showed high activity in local application contact tests, but did not prevent feeding damage. The effect was considerably inferior to that of Compound A. One of the reasons for this is that permethrin is susceptible to decomposition in the soil, indicating the need for practical comprehensive evaluation when developing termite control agents.

Test Example 2 An acetone solution of a test drug prepared by adding three times the amount of various pyrethroid synergists to Compound A was applied with a microsyringe to the backs of house termites, the thoracic back plate of adult house flies, and the backs of Spodoptera japonica, and 48 hours later. The synergistic effect of the insecticidal power of the synergist was examined based on the mortality rate of the insects, and the results were as follows.

Note that chlorpyrifos, an organic phosphorus agent, was used as a control agent.

As a result of the test, it was revealed that the combination of Compound A and our pyrethroid synergist piveronyl ptoxide exhibits a high synergistic effect specifically against the domestic termite.

On the other hand, in the case of the control drug chlorpyrifos, no differences in the synergistic effect were observed depending on the type of synergist or the type of insect tested.

A similar trend was observed for Yamato termites.

Test Example 3 In Test Example 2, the specific synergistic effect of piveronyl butoxide against the Japanese termite was clarified, so a wood treatment test was conducted using the following sample oil according to Test Example 1, and the following results were obtained. It was like that.

As a result of the test, the addition of viveroni μ-butoxide to Compound A significantly enhanced the feeding damage prevention effect in the wood treatment test, and it was confirmed that piveroni μ-butoxide is effective in reducing the concentration of Compound A. The mixing ratio of compound A and piveronyl butoxide is a weight loss rate of 3%.
Judging from the following criteria for passing, when the concentration of compound A is 0.1%, it is 1:1 to 1 to 2;
In the case of 0.05%, a sufficient effect was obtained with a ratio of 1:2 to 1:10. Furthermore, when the mixing ratio of Compound A and Piveroni μ-butoxide was 1:20, the efficacy was not increased to a degree proportional to the amount of Piveroni μ-butoxide added.

Patent Applicant: Dainippon Jomugiku Co., Ltd. Representative Director Ei Kamiyama Procedural Amendment (Voluntary) April 1, 1985 1, Indication of Case Patent Filed March 15, 1986 2, Name of Invention 12- Companion, A2;・R Bouji Invading Termite Control Agent 3, Relationship with the Amendment Case Patent Applicant Furigana Osakafu Osakashinishiku
Tosabori address (residence) 1-4-11, Tosabori, Nishi-ku, Osaka-shi, Osaka Prefecture Furigana: Dainipponji Kachi J Ugiku Name: Dainippon Jomugiku Co., Ltd. 4, Agent furigana: Osaka 7 Osa Chikara Shinishiku
Address: 1-4-118 Tosabori, Nishi-ku, Osaka-shi, Osaka Prefecture 7 Rigana Mr. Dainippon Jicheugik Name Dainippon Jorugiku Co., Ltd. 5 Date of amendment order: ``Voluntary amendment'' 6. Specification subject to amendment Full text 7. Contents of the amendment; engraving of the specification (no change in content) 61 Amendment to the procedure subject to amendment (voluntary) July 27, 1985 1. Indication of the case 1988 Patent Application No. 59225 3. Amendment Relationship with the case of a person who does
Corrected to ``under the environment''.

Claims (2)

[Claims] (1) 3-phenoxy-α-cyanobenzyl 2-(2-
Chloro-4-trifluoromethylphenylamino)-3
- A termite control agent characterized by containing methyl butanoate. (2) [3,4-(methylenedioxy)-6-propylbenzyl]butyl diethylene glycol ether as an auxiliary agent.
The termite control agent described in section 1).