JPS63189125A - Amniotic fluid turbidity measuring apparatus - Google Patents
Amniotic fluid turbidity measuring apparatusInfo
- Publication number
- JPS63189125A JPS63189125A JP62020967A JP2096787A JPS63189125A JP S63189125 A JPS63189125 A JP S63189125A JP 62020967 A JP62020967 A JP 62020967A JP 2096787 A JP2096787 A JP 2096787A JP S63189125 A JPS63189125 A JP S63189125A
- Authority
- JP
- Japan
- Prior art keywords
- amniotic fluid
- light
- fiber
- measuring device
- meconium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004381 amniotic fluid Anatomy 0.000 title claims description 41
- 239000000835 fiber Substances 0.000 claims description 33
- 239000012528 membrane Substances 0.000 claims description 16
- 210000001006 meconium Anatomy 0.000 claims description 15
- 230000003287 optical effect Effects 0.000 claims description 13
- 230000005284 excitation Effects 0.000 claims description 11
- 239000000126 substance Substances 0.000 claims description 9
- 238000001514 detection method Methods 0.000 claims description 7
- 238000005286 illumination Methods 0.000 claims description 6
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 238000004611 spectroscopical analysis Methods 0.000 claims 1
- 238000010586 diagram Methods 0.000 description 8
- 229910052724 xenon Inorganic materials 0.000 description 5
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 5
- 238000002189 fluorescence spectrum Methods 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 230000003595 spectral effect Effects 0.000 description 4
- 230000002159 abnormal effect Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000001605 fetal effect Effects 0.000 description 2
- 210000003754 fetus Anatomy 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000035606 childbirth Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、羊水中に排泄された胎便による羊水混濁の程
度を測定する羊水混濁測定装置に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to an amniotic fluid turbidity measurement device that measures the degree of amniotic fluid turbidity due to meconium excreted into amniotic fluid.
胎児に異常が発生して状態が悪くなった場合、胎児は羊
水中に胎便を排泄するので、胎便による羊水混濁の程度
を測定することにより胎児の状態を診断することができ
、そのため羊水混濁の程度を測定する装置として、従来
羊水鏡が使用されている。これは卵膜を通して羊水の状
態を目視で直接見ることにより混濁程度を診断するもの
であり、直接目視で観察するため、膝部を金属の筒で拡
張し、先端部に白色光源を備えた棒状の器具を挿入して
卵膜部分を照明し、照明された卵膜を通して羊水中の状
態を診断するものである。When an abnormality occurs in the fetus and the condition worsens, the fetus excretes meconium into the amniotic fluid, so the fetal condition can be diagnosed by measuring the degree of amniotic fluid turbidity due to meconium. Conventionally, an amnioscope has been used as a device to measure the degree of the disease. This is a method to diagnose the degree of turbidity by directly visually observing the state of amniotic fluid through the uterine membrane.For direct visual observation, a rod-shaped tube with a metal tube extended at the knee and a white light source at the tip is used. The device is inserted to illuminate the uterine membrane, and the state of the amniotic fluid can be diagnosed through the illuminated uterine membrane.
しかしながら従来の羊水鏡による診断では、診断のたび
に金属筒で膝部を拡張しなければならず、そのため連続
モニタは困難であり、手技が煩わしいため普及していな
いのが実情である。また、診察に際して白色光源で卵膜
部分を照明するが、はとんどの光は卵膜内に進入せず、
そのため羊水の混濁程度が特に著しい時にのみ診断が可
能となり、また目視による改悪評価のため定量判断が困
難であると共に、分娩早期の子宮口がまだ十分量大して
いない時は適用することができない。However, in conventional amnioscopic diagnosis, the knee region must be dilated with a metal tube each time a diagnosis is made, making continuous monitoring difficult and the procedure complicated, so it is not widely used. Also, during medical examinations, the uterine membrane is illuminated with a white light source, but most of the light does not penetrate into the uterine membrane.
Therefore, diagnosis is possible only when the degree of amniotic fluid turbidity is particularly significant, and it is difficult to make quantitative judgments due to the visual evaluation of deterioration, and it cannot be applied early in childbirth when the cervix has not yet enlarged sufficiently.
本発明は上記問題点を解決するためのもので、羊水中に
排泄された胎便が特定波長の励起光に対して特異的に螢
光を発する特性があることに着目し、これを利用して胎
便による羊水混濁の程度を容易に、定量的、客観的かつ
検出感度良く測定することのできる羊水混濁測定装置を
提供することを目的とする。The present invention is aimed at solving the above problems, and focuses on the fact that meconium excreted into amniotic fluid has the property of emitting fluorescence specifically in response to excitation light of a specific wavelength. An object of the present invention is to provide an amniotic fluid turbidity measurement device that can easily measure the degree of amniotic fluid turbidity due to meconium quantitatively, objectively, and with high detection sensitivity.
そのために本発明の羊水混濁測定装置は、観察用照明光
が導入される内視鏡の鉗子口を通り卵膜／ｌ
へ導かれる２分岐バンドルファイバーの投光用ファイ
バーを通して羊水に特定波長の励起光を照射する手段と
、羊水中の胎便に存在する螢光物質からの螢光を２分岐
バンドルファイバーの受光用ファイバーを通して受光し
分光する手段と、分光された螢光を検出する手段と、検
出出力を解析する手段とからなることを特徴とする。For this purpose, the amniotic fluid turbidity measuring device of the present invention allows the observation illumination light to pass through the forceps port of the endoscope to introduce the uterine membrane/l.
A means for irradiating excitation light of a specific wavelength to the amniotic fluid through a light emitting fiber of a bifurcated bundle fiber guided to the amniotic fluid, and a means for irradiating the amniotic fluid with excitation light of a specific wavelength through a light receiving fiber of the bifurcated bundle fiber. It is characterized by comprising a means for receiving and separating light, a means for detecting the separated fluorescent light, and a means for analyzing the detection output.
本発明の羊水混濁測定装置は、羊水中に排泄された胎便
が特定波長の励起光に対して特異的に螢光を発する特性
があることに着目し、観察用照明光が導入される内視鏡
の鉗子口を通り卵膜へ導かれる２分岐バンドルファイバ
ーの投光用ファイバーを通して羊水に特定波長の励起光
を照射し、羊水中に排泄された胎便に存在する螢光物質
からの螢光を２分岐バンドルファイバーの受光用ファイ
バーを通して受光し、その螢光スペクトルパターンから
容易に、かつ検出感度良く胎便による羊水の混濁の程度
を測定することができる。。The amniotic fluid turbidity measuring device of the present invention focuses on the fact that meconium excreted in amniotic fluid has the property of emitting fluorescence specifically in response to excitation light of a specific wavelength. The amniotic fluid is irradiated with excitation light of a specific wavelength through the light emitting fiber of a bifurcated bundle fiber that passes through the forceps opening of the mirror and is guided to the uterine membrane. Light is received through the light-receiving fiber of the bifurcated bundle fiber, and the degree of amniotic fluid turbidity due to meconium can be measured easily and with high detection sensitivity from the fluorescence spectrum pattern. .
以下、実施例を図面を参照して説明する。 Examples will be described below with reference to the drawings.
第１図は本発明の一実施例を示す図、第２図（イ）は２
分岐バンドルファイバー外観図、第２図（ロ）は第２図
（イ）のＡ−Ａ断面図、第３図は光源点燈タイミングを
示す図で、１はキセノンフラッシュランプ、２は集光レ
ンズ、３は分光器、４は集光レンズ、５はバンドルファ
イバー、５１は投光用ファイバー、５２は受光用ファイ
バー、６は内視鏡、７は集光レンズ、８はポリクロメー
タ、９は一次元センサ、１０はコンピュータ、１１はプ
リンター、１２は照明光源、１３は集光レンズ、１４は
ファイバー、１５は卵膜、１６はディスプレイである。Fig. 1 is a diagram showing an embodiment of the present invention, and Fig. 2 (a) is a diagram showing an embodiment of the present invention.
External view of the branched bundle fiber, Figure 2 (B) is a sectional view taken along line A-A in Figure 2 (A), and Figure 3 is a diagram showing the timing of turning on the light source, where 1 is a xenon flash lamp, and 2 is a condenser lens. , 3 is a spectroscope, 4 is a condenser lens, 5 is a bundle fiber, 51 is a light emitting fiber, 52 is a light receiving fiber, 6 is an endoscope, 7 is a condenser lens, 8 is a polychromator, 9 is a primary The original sensor, 10 is a computer, 11 is a printer, 12 is an illumination light source, 13 is a condenser lens, 14 is a fiber, 15 is a membrane, and 16 is a display.
図において、キセノンフランシュランプ１から発せられ
た光は集光レンズ２で集光され、分光器３に導入される
。この分光器３により羊水内型光物質を励起するのに適
した波長の光が選択され、集光レンズ４で集光された後
、第２図に示すような２分岐バンドルファイバー５の投
光用ファイバー５１に導入される。このバンドルファイ
バー５は内視鏡６の鉗子口を通り、母体内の卵膜１５へ
と導かれ、卵膜内の羊水に励起光を照射する。胎便には
特定波長の励起光に対し特異的に螢光を発する物質があ
り、羊水中に存在するこの螢光物質から発せられた螢光
は、バンドルファイバー５の受光用ファイバー５２を通
して外部に導かれ、集光レンズ７で集光された後ポリク
ロメータ８により分光される。ポリクロメータ８で分光
された螢光は、例えばフォトダイオードアレイ、ＰＣＤ
、［＋ＰＣＤ等の１次元センサ９により検出され、コン
ピュータ１０に取り込まれて解析され、診断情報となる
。この情報はプリンタ１１またはディスプレイ１６上に
表示される。In the figure, light emitted from a xenon Franche lamp 1 is focused by a condenser lens 2 and introduced into a spectrometer 3. The spectrometer 3 selects light with a wavelength suitable for exciting the optical substance in the amniotic fluid, and after condensing the light with the condenser lens 4, it is emitted by the bifurcated bundle fiber 5 as shown in FIG. fiber 51 for use. This bundle fiber 5 passes through the forceps port of the endoscope 6, is guided to the uterine membrane 15 inside the mother's body, and irradiates the amniotic fluid within the uterine membrane with excitation light. Meconium contains a substance that emits fluorescent light specifically in response to excitation light of a specific wavelength, and the fluorescent light emitted from this fluorescent substance present in amniotic fluid is guided to the outside through the light-receiving fiber 52 of the bundle fiber 5. The light is focused by a condensing lens 7 and then separated by a polychromator 8. The fluorescent light separated by the polychromator 8 is e.g.
, [+Detected by a one-dimensional sensor 9 such as a PCD, taken into the computer 10 and analyzed, and becomes diagnostic information. This information is displayed on printer 11 or display 16.
内視鏡６は卵膜１５とバンドルファイバー５との接触状
態を観察するためのものであり、その際の照明光源とし
て光源１２が用意されている。光源１２は例えばキセノ
ンフラッシュランプであり、その光は集光レンズ１３に
より集光され、ファイバー１４を通して内視鏡６の先端
部より卵膜１５に投光される。なお、キセノンフラッシ
ュランプ１と光源１２はコンピュータ１０により第３図
に示すように、時分割で交互に点燈するように制御され
る。The endoscope 6 is used to observe the contact state between the uterine membrane 15 and the bundle fiber 5, and a light source 12 is provided as an illumination light source at that time. The light source 12 is, for example, a xenon flash lamp, and its light is focused by a condensing lens 13 and projected onto the uterine membrane 15 from the tip of the endoscope 6 through a fiber 14 . Note that the xenon flash lamp 1 and the light source 12 are controlled by the computer 10 so that they are turned on alternately in a time-sharing manner, as shown in FIG.
第４図は羊水内螢光物質から発せられる螢光のスペクト
ルパターンを示す図で、同図（イ）は胎便を含まない正
常羊水螢光スペクトルパターン、同図（ロ）は胎便を含
む混濁羊水のスペクトルパターンである。Figure 4 shows the spectral pattern of fluorescence emitted from fluorescent substances in amniotic fluid. Figure (a) shows the fluorescence spectrum pattern of normal amniotic fluid that does not contain meconium, and (b) shows the turbid amniotic fluid that contains meconium. This is the spectral pattern of
このように、スペクトルパターンから胎便が排泄されて
いるか否か検出することができると共に、ピーク強度か
ら羊水混濁の程度を知ることができる。In this way, it is possible to detect whether meconium has been excreted from the spectral pattern, and also to know the degree of amniotic fluid turbidity from the peak intensity.
第５図は本発明の他の実施例を示す図で、第１図と同一
番号は同一内容を示している。図中、２０は光学フィル
ター、２１は光学フィルター群、２２は検出器、２３は
データ処理・制御装置である。FIG. 5 is a diagram showing another embodiment of the present invention, and the same numbers as in FIG. 1 indicate the same contents. In the figure, 20 is an optical filter, 21 is an optical filter group, 22 is a detector, and 23 is a data processing/control device.
図において、キセノンフラッシュランプ１から発せられ
た光は光学フィルタ２０により羊水中の螢光物質を励起
するのに適した波長のものが選択され、集光レンズ４で
集光された後、２分岐バンドルファイバー５の投光用フ
ァイバー５１に導入され、母体内の卵膜１５へと導かれ
、卵膜内の羊水に励起光を照射する。羊水中に存在する
螢光物質から発せられた螢光は、バンドルファイバー５
の受光用ファイバー５２を通して外部に導かれ、光学フ
ィルタ群２１で分光される。光学フィルタ群２１は異常
羊水のスペクトルパターンの特徴を描出する複数の光学
フィルターにより構成され、例えば異常羊水の螢光ピー
クである５８０ｎｍ。In the figure, light emitted from a xenon flash lamp 1 is selected by an optical filter 20 to have a wavelength suitable for exciting fluorescent substances in amniotic fluid, and after being condensed by a condensing lens 4, it is split into two branches. The excitation light is introduced into the light emitting fiber 51 of the bundle fiber 5, guided to the uterine membrane 15 in the mother's body, and irradiates the amniotic fluid within the uterine membrane. The fluorescent light emitted from the fluorescent substance present in the amniotic fluid is transmitted through the bundle fiber 5.
The light is guided to the outside through the light-receiving fiber 52 and separated into spectra by the optical filter group 21. The optical filter group 21 is composed of a plurality of optical filters that depict the characteristics of the spectral pattern of abnormal amniotic fluid, for example, 580 nm, which is the fluorescence peak of abnormal amniotic fluid.
谷間である５ ６０ｎｍ、螢光のほとんど無い６８０ｎ
ｍ等（第４図参照）の光学フィルタが採用される。光学
フィルタ群２１により分光された螢光は集光レンズ７に
より集光された後、例えばシリコンフォトダイオード、
光電子増倍管等の検出器２２により検出されてデータ処
理・制御装置２３へ送られる。データ処理・制御装置２
３は検出結果に基づいて光学フィルタ群２１より適宜フ
ィルタを選択すると共に、データを解析し、診断情報が
得られる。なお、この情報はプリンタ１１またはディス
プレイ１６に出力される。560nm which is a valley, 680n with almost no fluorescence
An optical filter such as m (see FIG. 4) is employed. The fluorescent light separated by the optical filter group 21 is condensed by a condensing lens 7, and then, for example, a silicon photodiode,
It is detected by a detector 22 such as a photomultiplier tube and sent to a data processing/control device 23. Data processing/control device 2
3 selects an appropriate filter from the optical filter group 21 based on the detection results, analyzes the data, and obtains diagnostic information. Note that this information is output to the printer 11 or the display 16.
以上のように本発明によれば、羊水中に排泄された胎便
が特定波長の励起光に対して特異的に螢光を発する特性
があることに着目し、これを利用することによりファイ
バーを肺部より挿入するのみで容易に胎便による羊水混
濁の程度を測定することができると共に、飛躍的に検出
感度を向上させることができる。また従来不可能であっ
た混濁程度の定量化と経時的な変化を客観的に測定する
ことが可能となり、従来の混濁程度の２値的評価から脱
して新しい胎児情報を得ることが可能となる。As described above, the present invention focuses on the fact that meconium excreted in amniotic fluid has the property of emitting fluorescence specifically in response to excitation light of a specific wavelength, and by utilizing this property, it is possible to connect fibers to the lungs. It is possible to easily measure the degree of amniotic fluid turbidity due to meconium by simply inserting the meconium into the body, and the detection sensitivity can be dramatically improved. In addition, it becomes possible to quantify the degree of opacity and objectively measure changes over time, which was previously impossible, and it becomes possible to move away from the conventional binary evaluation of the degree of opacity and obtain new fetal information. .
第１図は本発明の羊水混濁測定装置の一実施例を示すブ
ロック図、第２図（イ）は第１図の要部の側面図、第２
図（ロ）は第２図（イ）のＡ−Ａ断面図、第３図は本発
明の光源点燈タイミングを説明するための図、第４図（
イ）は正常な羊水内螢光物質の螢光スペクトルパターン
を示す図、第４図（ロ）は異常な羊水内螢光物質の螢光
スペクトルパターンを示す図、第５図は本発明の羊水混
濁測定装置の他の実施例を示す図である。
１・・・キセノホンフラッシュランプ、２・・・集光レ
ンズ、３・・・分光器、４・・・集光レンズ、５・・・
バンドルファイバー、５１・・・投光用ファイバー、５
２・・・受光用ファイバー、６・・・内視鏡、７・・・
集光レンズ、８・・・ポリクロメータ、９・・・−次元
センサ、１０・・・コンピュータ、１１・・・プリンタ
ー、１２・・・照明光源、１３・・・集光レンズ、１４
・・・ファイバー、１５・・・卵膜、１６・・・ディス
プレイ、２０・・・光学フィルタ、２１・・・光学フィ
ルタ群、２２・・・検出器、２３・・・データ処理・制
御装置。
出 願 人 浜松ホトニクス株式会社（外１名）
代 理 人 弁理士 蛭 川 昌 信第２図
＾
（ロノ
第３図
→を
第４図
（ロノFIG. 1 is a block diagram showing an embodiment of the amniotic fluid turbidity measuring device of the present invention, FIG.
Figure (B) is a sectional view taken along line A-A in Figure 2 (A), Figure 3 is a diagram for explaining the timing of turning on the light source of the present invention, and Figure 4 (
A) is a diagram showing the fluorescence spectrum pattern of a normal fluorescent substance in amniotic fluid, FIG. 4(B) is a diagram showing a fluorescence spectrum pattern of an abnormal fluorescent substance in amniotic fluid, and FIG. It is a figure which shows another Example of a turbidity measuring device. 1... Xenophone flash lamp, 2... Condensing lens, 3... Spectrometer, 4... Condensing lens, 5...
Bundle fiber, 51... Light projection fiber, 5
2... Light receiving fiber, 6... Endoscope, 7...
Condensing lens, 8... Polychromator, 9... -dimensional sensor, 10... Computer, 11... Printer, 12... Illumination light source, 13... Condensing lens, 14
...Fiber, 15... Egg membrane, 16... Display, 20... Optical filter, 21... Optical filter group, 22... Detector, 23... Data processing/control device. Applicant Hamamatsu Photonics Co., Ltd. (1 other person) Agent Patent attorney Masanobu Hirukawa Figure 2 (Rono Figure 3 → Figure 4 (Rono
Claims (3)
、卵膜へ導かれる２分岐バンドルファイバーの投光用フ
ァイバーを通して羊水に特定波長の励起光を照射する手
段と、羊水中の胎便に存在する螢光物質からの螢光を２
分岐バンドルファイバーの受光用ファイバーを通して受
光し分光する手段と、分光された螢光を検出する手段と
、検出出力を解析する手段とからなる羊水混濁測定装置
。(1) means for irradiating amniotic fluid with excitation light of a specific wavelength through a light emitting fiber of a bifurcated bundle fiber that passes through the forceps port of an endoscope into which observation illumination light is introduced and is guided to the uterine membrane; The fluorescence from the fluorescent substances present in the meconium of
An amniotic fluid turbidity measuring device comprising a means for receiving light through a light receiving fiber of a branched bundle fiber and dispersing it, a means for detecting the separated fluorescence, and a means for analyzing the detection output.
点灯される特許請求の範囲第１項記載の羊水混濁測定装
置。(2) The amniotic fluid opacity measuring device according to claim 1, wherein the observation illumination light and the excitation light are turned on alternately in a time-sharing manner.
検出時選択制御される特許請求の範囲第１項記載の羊水
混濁測定装置。(3) The means for spectroscopy consists of a group of optical filters,
The amniotic fluid turbidity measuring device according to claim 1, which is selectively controlled at the time of detection.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62020967A JPH0817770B2 (en) | 1987-01-31 | 1987-01-31 | Amniotic fluid turbidity measuring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62020967A JPH0817770B2 (en) | 1987-01-31 | 1987-01-31 | Amniotic fluid turbidity measuring device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63189125A true JPS63189125A (en) | 1988-08-04 |
| JPH0817770B2 JPH0817770B2 (en) | 1996-02-28 |
Family
ID=12041940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62020967A Expired - Lifetime JPH0817770B2 (en) | 1987-01-31 | 1987-01-31 | Amniotic fluid turbidity measuring device |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0817770B2 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000500378A (en) * | 1995-11-20 | 2000-01-18 | ユタ・メディカル・プロダクツ・インコーポレーテッド | In utero meconium detection system |
| JP2001517518A (en) * | 1997-09-29 | 2001-10-09 | ボストン サイエンティフィック コーポレイション | Internal fluorescence imaging module for endoscope |
| JP2011500196A (en) * | 2007-10-16 | 2011-01-06 | テル ハショマー メディカル リサーチ インフラストラクチャー アンド サーヴィシーズ リミテッド | Apparatus and method for confirming meconium in amniotic fluid |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59173020U (en) * | 1983-05-06 | 1984-11-19 | オムロン株式会社 | Living body fluorescent endoscopy device |
-
1987
- 1987-01-31 JP JP62020967A patent/JPH0817770B2/en not_active Expired - Lifetime
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59173020U (en) * | 1983-05-06 | 1984-11-19 | オムロン株式会社 | Living body fluorescent endoscopy device |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000500378A (en) * | 1995-11-20 | 2000-01-18 | ユタ・メディカル・プロダクツ・インコーポレーテッド | In utero meconium detection system |
| JP2001517518A (en) * | 1997-09-29 | 2001-10-09 | ボストン サイエンティフィック コーポレイション | Internal fluorescence imaging module for endoscope |
| JP4781528B2 (en) * | 1997-09-29 | 2011-09-28 | ボストン サイエンティフィック リミテッド | Internal fluorescence imaging module for endoscope |
| JP2011500196A (en) * | 2007-10-16 | 2011-01-06 | テル ハショマー メディカル リサーチ インフラストラクチャー アンド サーヴィシーズ リミテッド | Apparatus and method for confirming meconium in amniotic fluid |
| US8768425B2 (en) | 2007-10-16 | 2014-07-01 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Device and method for identification of meconium in amniotic fluid |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0817770B2 (en) | 1996-02-28 |
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